GO:0031670

From wiki-pain
Jump to: navigation, search
Name cellular response to nutrient
Categary Process
Go Slim No
Go Link GO:0031670
Unique Molecular Interactions 116
Total Molecular Interactions 138
Total Single Events 1432
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to nutrient. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to nutrient. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT138961 Dbi Positive_regulation of Chkb 1 0.00 3.05 3.99
2 INT138959 Dbi Positive_regulation of Penk 1 0.01 3.05 3.99
3 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
4 INT138962 Dbi Positive_regulation of Pomc 1 0.00 1.53 2
5 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2
6 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2
7 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52
8 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44
9 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
10 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
11 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
12 INT41093 Binding of Dbi and Nil 1 0.00 0 0.93
13 INT55204 Prl Positive_regulation of Localization of Dbi 1 0.02 0 0.91
14 INT161048 Nrm Positive_regulation of Prdm4 1 0.56 1.47 0.86
15 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
16 INT87646 Dbi Regulation of Olfr1507 1 0.00 0.69 0.72
17 INT99743 Olr1742 Regulation of Gene_expression of Hmox1 1 0.00 0 0.68
18 INT99744 Calca Positive_regulation of Positive_regulation of Hmox1 1 0.48 0 0.64
19 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
20 INT32479 Gh1 Negative_regulation of Dbi 1 0.01 0 0.51
21 INT145435 Binding of CPOX and HMOX1 1 0.01 0.42 0.49
22 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47
23 INT34982 Trh Regulation of Dbi 1 0.12 0 0.47
24 INT34984 Negative_regulation of Trh Regulation of Dbi 1 0.19 0 0.47
25 INT165677 NFE2L2 Negative_regulation of Positive_regulation of HMOX1 1 0.40 0.32 0.44
26 INT165678 NFE2L2 Negative_regulation of HMOX1 1 0.40 0.31 0.43
27 INT34983 Gene_expression of Dbi Positive_regulation of Localization of Trh 1 0.22 0 0.42
28 INT34981 Gene_expression of Dbi Positive_regulation of Localization of Prl 1 0.23 0 0.41
29 INT164371 Dbi Regulation of Pomc 1 0.19 0.17 0.35
30 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31
31 INT304278 CCNE1 Positive_regulation of IL8 1 0.02 1.93 0.31
32 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31
33 INT260433 Dbi Positive_regulation of Cd8a 1 0.00 0.13 0.3
34 INT91751 Binding of PTGS2 and Hmox1 1 0.00 0.21 0.27
35 INT82194 Dbi Regulation of Oprd1 1 0.12 0.07 0.26
36 INT349652 Positive_regulation of Hmox1 Negative_regulation of Positive_regulation of Itk 1 0.01 0.85 0.25
37 INT43532 Dbi Negative_regulation of Localization of LH 1 0.15 0.75 0.23
38 INT35472 Dbi Regulation of Gnrh1 1 0.06 0.17 0.22
39 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22
40 INT35468 Dbi Regulation of Prl 1 0.05 0.17 0.22
41 INT349647 Eif2ak1 Positive_regulation of Positive_regulation of Hmox1 1 0.00 1.07 0.2
42 INT349646 Eif2ak1 Regulation of Gene_expression of Hmox1 1 0.00 0.78 0.2
43 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19
44 INT35471 Dbi Negative_regulation of Localization of Gnrh1 1 0.05 0.14 0.19
45 INT348059 Dbi Negative_regulation of Binding of Mpo 1 0.08 0.43 0.19
46 INT94355 NOVA2 Positive_regulation of Dbi 1 0.00 0.15 0.18
47 INT81296 Positive_regulation of Pparg Regulation of Gene_expression of Hmox1 1 0.25 0.17 0.17
48 INT42521 Pomc Regulation of Dbi 1 0.06 0 0.17
49 INT32665 Pomc Negative_regulation of Dbi 1 0.06 0 0.17
50 INT5520 Negative_regulation of Dbi Negative_regulation of Gene_expression of Crh 1 0.21 0.44 0.16
51 INT5517 Negative_regulation of Dbi Negative_regulation of Crh 1 0.27 0.44 0.16
52 INT355410 Ins1 Regulation of Gene_expression of Dbi 1 0.07 0.57 0.16
53 INT231757 TLR4 Positive_regulation of Negative_regulation of HMOX1 1 0.26 1.37 0.15
54 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14
55 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14
56 INT355408 Ins1 Regulation of Dbi 1 0.07 0.58 0.14
57 INT231761 TNF Negative_regulation of HMOX1 1 0.19 1.2 0.12
58 INT231764 TLR4 Negative_regulation of HMOX1 1 0.27 1.54 0.11
59 INT231768 Binding of HMOX1 and TLR4 1 0.23 0.95 0.11
60 INT231772 TNF Positive_regulation of Gene_expression of HMOX1 1 0.21 0.96 0.1
61 INT43530 Dbi Negative_regulation of LH 1 0.18 0.3 0.1
62 INT5519 Dbi Negative_regulation of Crh 1 0.31 0.28 0.1
63 INT43529 Dbi Negative_regulation of Gene_expression of LH 1 0.13 0.3 0.1
64 INT231773 IRF6 Negative_regulation of Gene_expression of HMOX1 1 0.06 1.27 0.09
65 INT94353 Crh Negative_regulation of Positive_regulation of Dbi 1 0.03 0.14 0.08
66 INT94354 Crh Negative_regulation of Dbi 1 0.03 0.14 0.08
67 INT245118 RBM45 Negative_regulation of CDKN2B 1 0.01 1.41 0.08
68 INT245119 Negative_regulation of RBM45 Negative_regulation of CDKN2B 1 0.01 1.43 0.08
69 INT43528 Dbi Regulation of Localization of LH 1 0.09 0.21 0.07
70 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07
71 INT244290 Il6 Positive_regulation of Hmox1 1 0.38 0.09 0.07
72 INT244291 Nos2 Positive_regulation of Positive_regulation of Hmox1 1 0.34 0.07 0.07
73 INT231760 TNF Positive_regulation of Protein_catabolism of HMOX1 1 0.31 0.41 0.06
74 INT349645 Eif2ak1 Positive_regulation of Hmox1 1 0.00 0.18 0.05
75 INT231758 IRF6 Regulation of Gene_expression of HMOX1 1 0.08 0.23 0.05
76 INT231766 TLR4 Negative_regulation of Gene_expression of HMOX1 1 0.28 0.71 0.05
77 INT231771 Binding of HMOX1 and TNF 2 0.14 1.41 0.04
78 INT231759 IL10 Positive_regulation of Gene_expression of HMOX1 1 0.06 0.7 0.04
79 INT349648 Eif2ak1 Positive_regulation of Gene_expression of Hmox1 1 0.00 0.17 0.04
80 INT231775 TLR4 Regulation of Gene_expression of HMOX1 1 0.29 0.68 0.04
81 INT231774 Gene_expression of TLR4 Positive_regulation of Gene_expression of HMOX1 1 0.30 0.68 0.04
82 INT231762 TLR4 Positive_regulation of Gene_expression of HMOX1 1 0.30 0.68 0.04
83 INT283720 Id2 Negative_regulation of Transcription of Cdkn2b 1 0.18 0.11 0.03
84 INT280601 Binding of HIVEP1 and Dbi 1 0.00 1.57 0.03
85 INT335492 CREM Positive_regulation of Transcription of HMOX1 1 0.00 0.9 0.03
86 INT269932 Pcna Negative_regulation of Cdkn2b 1 0.09 0.07 0
87 INT215686 Cdkn2b Negative_regulation of Cdkn1c 1 0.01 0 0
88 INT229818 Fos Positive_regulation of Hmox1 1 0.43 0.37 0
89 INT269924 Smad3 Regulation of Gene_expression of Cdkn2b 1 0.23 0.26 0
90 INT269926 Cdkn2b Negative_regulation of Pcna 1 0.08 0.07 0
91 INT215700 Binding of Cdkn2b and Cdk6 1 0.02 0 0
92 INT260395 Positive_regulation of Adipoq Negative_regulation of Gene_expression of Hmox1 1 0.34 1.4 0
93 INT269936 Smad2 Positive_regulation of Cdkn2b 1 0.15 0.07 0
94 INT259670 CSE Positive_regulation of Hmox1 1 0.06 0.97 0
95 INT262746 Binding of Dbi and RN7SL2 1 0.00 0 0
96 INT269950 Sox17 Negative_regulation of Gene_expression of Cdkn2b 1 0.27 0.24 0
97 INT330735 GSTK1 Regulation of HMOX1 1 0.08 0.25 0
98 INT260398 Dclk2 Regulation of Gene_expression of Hmox1 1 0.01 1.02 0
99 INT314688 Binding of CCNE1 and CDK2 1 0.04 1.41 0
100 INT314678 Binding of CCNE1 and CCNE2 1 0.03 1.41 0
101 INT269929 Binding of Cdkn2b and Smad3 1 0.18 0.89 0
102 INT284915 Binding of CDKN2B and HIST2H3C 1 0.05 0.43 0
103 INT169485 Dbi Regulation of Prkca 1 0.02 0.08 0
104 INT35470 Binding of Prl and Dbi 1 0.05 0.17 0
105 INT215688 Cdkn2b Negative_regulation of Kras 1 0.00 0 0
106 INT169484 Dbi Regulation of Oprk1 1 0.01 0.07 0
107 INT285042 Dbi Regulation of Gene_expression of Rho 1 0.01 0 0
108 INT262747 Binding of CHN1 and Dbi 1 0.01 0 0
109 INT215694 Cdkn2b Negative_regulation of Cdkn1b 1 0.01 0 0
110 INT260393 Hmox1 Regulation of Positive_regulation of Bcl2 1 0.22 0.86 0
111 INT183740 Dbi Negative_regulation of A230066D03Rik 1 0.00 0.69 0
112 INT301906 Binding of HMOX1 and HSD11B1 1 0.05 2.41 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to nutrient. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to nutrient. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2
2 INT5989 Positive_regulation of Dbi 79 0.49 24.38 32.56
3 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
4 INT5988 Localization of Dbi 74 0.81 17.52 24.09
5 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
6 INT11762 Regulation of Dbi 40 0.62 7.83 14.48
7 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
8 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
9 INT5512 Negative_regulation of Dbi 32 0.36 7.33 9.1
10 INT30638 Positive_regulation of Gene_expression of Dbi 17 0.69 4.63 8.28
11 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12
12 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25
13 INT20343 Positive_regulation of Localization of Dbi 21 0.63 5.01 6.61
14 INT19779 Binding of Dbi 41 0.36 8.8 5.87
15 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74
16 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87
17 INT97096 Regulation of Hmox1 18 0.61 6.42 3.9
18 INT27642 Regulation of Gene_expression of Dbi 10 0.44 2.55 3.66
19 INT135773 Negative_regulation of Gene_expression of HMOX1 31 0.53 28.31 3.32
20 INT20344 Regulation of Localization of Dbi 8 0.49 1.97 3.31
21 INT81291 Regulation of Gene_expression of Hmox1 11 0.60 8.78 2.46
22 INT99742 Negative_regulation of Gene_expression of Hmox1 12 0.58 9.94 1.77
23 INT32543 Negative_regulation of Gene_expression of Dbi 6 0.42 2.46 1.67
24 INT91232 Regulation of Positive_regulation of Hmox1 5 0.45 2.43 1.55
25 INT103305 Positive_regulation of Positive_regulation of Hmox1 8 0.49 4.81 1.49
26 INT100420 Regulation of HMOX1 10 0.35 6.68 1.48
27 INT165680 Transcription of HMOX1 7 0.71 11.2 1.41
28 INT127283 Regulation of Gene_expression of HMOX1 14 0.61 11.8 1.28
29 INT91320 Localization of Hmox1 8 0.81 4.06 1.28
30 INT115831 Transcription of Hmox1 16 0.66 5.31 1.14
31 INT32541 Positive_regulation of Positive_regulation of Dbi 2 0.39 0.5 1.14
32 INT123554 Transcription of Dbi 5 0.72 1.13 1.13
33 INT116529 Binding of HMOX1 10 0.47 15.38 1.04
34 INT105445 Localization of HMOX1 5 0.71 3.11 0.98
35 INT30942 Regulation of Regulation of Dbi 2 0.07 0.12 0.98
36 INT82568 Protein_catabolism of Hmox1 5 0.86 1.03 0.79
37 INT5504 Negative_regulation of Negative_regulation of Dbi 2 0.25 0.43 0.63
38 INT32542 Negative_regulation of Positive_regulation of Dbi 2 0.17 0 0.63
39 INT287003 Negative_regulation of Positive_regulation of Hmox1 2 0.34 3.1 0.63
40 INT58987 Positive_regulation of Ccne1 1 0.49 0 0.59
41 INT58988 Positive_regulation of Gene_expression of Ccne1 1 0.67 0 0.59
42 INT58989 Gene_expression of Ccne1 2 0.75 0.79 0.58
43 INT21882 Negative_regulation of Localization of Dbi 3 0.45 0.28 0.55
44 INT165681 Positive_regulation of Transcription of HMOX1 2 0.69 4.29 0.53
45 INT100191 Gene_expression of Cdkn2b 1 0.65 0.06 0.51
46 INT225223 Localization of Cdkn2b 2 0.62 1.29 0.37
47 INT42288 Negative_regulation of Binding of Dbi 1 0.13 0 0.37
48 INT157157 Negative_regulation of Localization of HMOX1 1 0.37 0.74 0.37
49 INT281659 Regulation of Transcription of HMOX1 2 0.27 2.12 0.33
50 INT304298 Positive_regulation of CCNE1 2 0.46 2.95 0.31
51 INT196426 Gene_expression of Cdkn2b 6 0.67 4.29 0.29
52 INT135772 Regulation of Positive_regulation of HMOX1 3 0.39 1.52 0.29
53 INT91231 Binding of Hmox1 4 0.36 0.29 0.27
54 INT123541 Regulation of Gene_expression of Cdkn2b 1 0.26 0.06 0.26
55 INT42569 Binding of Ccne1 1 0.21 0.38 0.19
56 INT19780 Protein_catabolism of Dbi 3 0.29 0.43 0.17
57 INT115829 Regulation of Transcription of Hmox1 1 0.35 1.03 0.17
58 INT201467 Protein_catabolism of HMOX1 2 0.77 0.83 0.13
59 INT302244 Negative_regulation of CCNE1 1 0.01 1.03 0.1
60 INT245123 Gene_expression of CDKN2B 6 0.68 3.62 0.07
61 INT184989 Positive_regulation of CDKN2B 3 0.47 2.77 0.07
62 INT185030 Binding of CDKN2B 3 0.35 2.6 0.07
63 INT115824 Positive_regulation of Transcription of Hmox1 3 0.45 0.43 0.06
64 INT173183 Regulation of CCNE1 1 0.05 0.4 0.06
65 INT293311 Positive_regulation of Positive_regulation of HMOX1 3 0.69 1.99 0.04
66 INT314842 Phosphorylation of Cdkn2b 1 0.71 0.61 0.03
67 INT302266 Negative_regulation of Phosphorylation of CCNE1 1 0.02 0.29 0.03
68 INT283688 Transcription of Cdkn2b 1 0.28 0.11 0.03
69 INT314725 Gene_expression of CCNE1 3 0.52 2.45 0
70 INT284972 Negative_regulation of CDKN2B 3 0.44 1.13 0
71 INT196419 Negative_regulation of Cdkn2b 2 0.12 0.55 0
72 INT196429 Negative_regulation of Gene_expression of Cdkn2b 2 0.27 0.8 0
73 INT123553 Positive_regulation of Transcription of Dbi 2 0.69 0.52 0
74 INT284937 Negative_regulation of Positive_regulation of CDKN2B 1 0.37 0.31 0
75 INT269911 Positive_regulation of Cdkn2b 1 0.31 0 0
76 INT19781 Negative_regulation of Protein_catabolism of Dbi 1 0.18 0 0
77 INT337766 Phosphorylation of Hmox1 1 0.79 0.08 0
78 INT284941 Transcription of CDKN2B 1 0.63 1.59 0
79 INT284970 Positive_regulation of Gene_expression of CDKN2B 1 0.61 0.55 0
80 INT204068 Negative_regulation of Gene_expression of Ccne1 1 0.03 0.47 0
81 INT269886 Binding of Cdkn2b 1 0.23 0.2 0
82 INT147085 Binding of Cdkn2b 1 0.10 0.07 0
83 INT314716 Positive_regulation of Gene_expression of CCNE1 1 0.16 1.48 0
84 INT284988 Positive_regulation of Transcription of CDKN2B 1 0.44 1.1 0
85 INT337767 Positive_regulation of Phosphorylation of Hmox1 1 0.49 0.08 0
86 INT302253 Phosphorylation of CCNE1 1 0.03 0.29 0
87 INT280597 Positive_regulation of Negative_regulation of Dbi 1 0.03 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox