GO:0031681

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Name G-protein beta-subunit binding
Categary Function
Go Slim No
Go Link GO:0031681
Unique Molecular Interactions 500
Total Molecular Interactions 730
Total Single Events 6187
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for G-protein beta-subunit binding. They are ordered first by their pain relevance and then by number of times they were reported for G-protein beta-subunit binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
3 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29
4 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
5 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
6 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
7 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
8 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
9 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
10 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
11 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03
12 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
13 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
14 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68
15 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
16 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
17 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
18 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
19 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
20 INT154226 Positive_regulation of Oprk1 Negative_regulation of Negative_regulation of Oprm1 1 0.28 0.07 2.32
21 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
22 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
23 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14
24 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
25 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
26 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
27 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
28 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
29 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95
30 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
31 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
32 INT169498 Binding of Oprm1 and Mirlet7a-1 1 0.32 0 1.9
33 INT153582 Binding of Oprm1 and Hint1 1 0.01 0 1.87
34 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86
35 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
36 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84
37 INT169502 Mirlet7a-1 Regulation of Oprm1 1 0.53 0 1.81
38 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
39 INT168925 Binding of Oprm1 and Imraq2 1 0.04 0.13 1.78
40 INT168924 Positive_regulation of Binding of Oprm1 and Imraq2 1 0.06 0.13 1.78
41 INT211746 Binding of Oprm1 and Mors1 1 0.08 0 1.78
42 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
43 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
44 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
45 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
46 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
47 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
48 INT315180 Gene_expression of Mors1 Positive_regulation of Gene_expression of Oprm1 1 0.03 0.48 1.64
49 INT315181 Gene_expression of Mors1 Positive_regulation of Oprm1 1 0.03 0.48 1.64
50 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63
51 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63
52 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
53 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
54 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59
55 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
56 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
57 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
58 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55
59 INT111828 UPB1 Positive_regulation of Oprm1 1 0.00 0.85 1.53
60 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
61 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
62 INT8735 Oprm1 Positive_regulation of Scn4a 1 0.00 0 1.49
63 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46
64 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
65 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
66 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
67 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
68 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
69 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
70 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43
71 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
72 INT43814 Binding of Cpe and Oprm1 1 0.08 0 1.41
73 INT142852 Oprm1 Positive_regulation of Oprd1 1 0.41 0.06 1.41
74 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
75 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
76 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
77 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31
78 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
79 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 0.27 0.9 1.31
80 INT168229 Oprm1 Regulation of Cea 1 0.10 0.26 1.3
81 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29
82 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
83 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
84 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
85 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
86 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
87 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
88 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
89 INT207548 U Negative_regulation of Gene_expression of Oprm1 1 0.01 0.46 1.26
90 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
91 INT87375 Binding of Gabrg1 and Oprm1 1 0.00 0.83 1.25
92 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25
93 INT151444 Binding of Oprm1 and Pag1 1 0.00 1.5 1.24
94 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
95 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24
96 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
97 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
98 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23
99 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22
100 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
101 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
102 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21
103 INT124157 Oprm1 Negative_regulation of Gnb5 1 0.25 0.4 1.19
104 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
105 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
106 INT153588 Binding of HINT1 and Oprm1 1 0.06 0 1.17
107 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
108 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
109 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
110 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
111 INT88778 Binding of Oprm1 and Pomc 3 0.21 0.56 1.14
112 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
113 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
114 INT110522 Oprm1 Positive_regulation of Oprk1 1 0.11 0 1.12
115 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
116 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11
117 INT133497 Binding of Oprm1 and Cckbr 1 0.03 0 1.1
118 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
119 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
120 INT114007 Binding of Crygs and Oprm1 1 0.03 0 1.09
121 INT156238 Binding of F2rl1 and Tnfsf14 1 0.08 2.85 1.08
122 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
123 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
124 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
125 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
126 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
127 INT150621 Binding of Oprm1 and Oprd1 1 0.00 0.08 1.02
128 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02
129 INT106956 Oprm1 Positive_regulation of Positive_regulation of P9Ehs1 1 0.08 0.54 1.02
130 INT116751 Positive_regulation of Oprm1 Positive_regulation of Pik3cd 1 0.28 0.38 1.01
131 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
132 INT98002 Positive_regulation of Oprm1 Positive_regulation of P9Ehs1 1 0.10 0 1
133 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
134 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
135 INT70105 SCD Positive_regulation of Oprm1 1 0.01 0 1
136 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
137 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
138 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1
139 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
140 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
141 INT169500 Negative_regulation of Mirlet7a-1 Regulation of Oprm1 1 0.37 0 0.99
142 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
143 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
144 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97
145 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
146 INT317543 Pag1 Positive_regulation of Oprm1 1 0.12 0.73 0.97
147 INT137919 Binding of Oprm1 and Stat3 1 0.30 0 0.97
148 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
149 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
150 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
151 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
152 INT146096 Positive_regulation of Binding of Oprm1 and Rgs9 1 0.44 0 0.94
153 INT65024 Binding of Oprm1 and Penk 1 0.03 0 0.93
154 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92
155 INT79123 Binding of Pnoc and Oprm1 3 0.14 0 0.91
156 INT317530 Negative_regulation of Binding of Nos1 and Oprm1 1 0.21 0.06 0.9
157 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
158 INT281089 Binding of Gria1 and Ltp 1 0.25 0.6 0.9
159 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89
160 INT83417 Binding of OPRL1 and Oprm1 1 0.01 0 0.89
161 INT97184 Oprm1 Regulation of Gene_expression of Pomc 1 0.31 0 0.89
162 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89
163 INT126268 Tpsab1 Positive_regulation of F2rl1 2 0.35 1.65 0.88
164 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88
165 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88
166 INT112153 Regulation of Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.87
167 INT63859 Oprm1 Negative_regulation of Oprm1 1 0.10 0.08 0.86
168 INT63858 Oprm1 Negative_regulation of Penk 1 0.05 0.08 0.86
169 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86
170 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
171 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
172 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86
173 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85
174 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
175 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
176 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84
177 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
178 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83
179 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
180 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
181 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
182 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
183 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
184 INT139745 Positive_regulation of Binding of Oprm1 and Arrb2 1 0.28 0.14 0.81
185 INT156239 Tnfsf14 Positive_regulation of F2rl1 1 0.09 2.4 0.81
186 INT124292 Binding of Trpv1 and F2rl1 1 0.46 1.1 0.81
187 INT112154 Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.81
188 INT6409 Binding of NFKBIL1 and Oprm1 1 0.00 0 0.8
189 INT106838 Lyar Regulation of Oprm1 1 0.04 0.28 0.8
190 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
191 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 0.46 0.44 0.79
192 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
193 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
194 INT199495 Il4 Positive_regulation of Positive_regulation of Oprm1 1 0.00 0.98 0.78
195 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
196 INT55923 Penk Regulation of Transcription of Oprm1 1 0.26 0 0.78
197 INT55922 Penk Regulation of Oprm1 1 0.26 0 0.78
198 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
199 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77
200 INT302119 Positive_regulation of Binding of Oprm1 and Ppp1r9b 1 0.02 0 0.77

Single Events

The table below shows the top 100 pain related interactions that have been reported for G-protein beta-subunit binding. They are ordered first by their pain relevance and then by number of times they were reported in G-protein beta-subunit binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29
2 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71
3 INT6406 Binding of Oprm1 280 0.48 40.54 226.26
4 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
5 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85
6 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1
7 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
8 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
9 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
10 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
11 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
12 INT8733 Localization of Oprm1 61 0.75 7.55 64.61
13 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83
14 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65
15 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
16 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
17 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45
18 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5
19 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
20 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22
21 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
22 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95
23 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
24 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
25 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66
26 INT94658 Positive_regulation of F2rl1 51 0.70 33.65 27.46
27 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75
28 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
29 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78
30 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67
31 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
32 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02
33 INT90849 Gene_expression of F2rl1 55 0.78 31.31 20.65
34 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11
35 INT100732 Gene_expression of F2RL1 55 0.78 38.89 19.45
36 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
37 INT118512 Gene_expression of F2r 33 0.63 26.56 18.26
38 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
39 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
40 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
41 INT33915 Regulation of Positive_regulation of Oprm1 22 0.60 2.44 16.43
42 INT68811 Regulation of Transcription of Oprm1 19 0.61 3.67 15.15
43 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
44 INT12658 Regulation of Binding of Oprm1 9 0.57 2.44 14.95
45 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
46 INT104674 Positive_regulation of F2rl1 35 0.65 27.76 14.16
47 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57
48 INT49538 Binding of Gria1 22 0.47 2.66 13.35
49 INT62523 Positive_regulation of Phosphorylation of Oprm1 11 0.53 0.75 12.51
50 INT111948 Positive_regulation of Gria1 23 0.61 7.55 12.03
51 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11
52 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08
53 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37
54 INT8072 Localization of Gria1 17 0.75 2.62 10.04
55 INT96298 Negative_regulation of Gria1 25 0.57 10.61 9.7
56 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
57 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4
58 INT20835 Negative_regulation of Negative_regulation of Oprm1 10 0.43 0.56 8.96
59 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72
60 INT98835 Positive_regulation of Transcription of Oprm1 15 0.65 2.47 8.67
61 INT18021 Positive_regulation of Binding of Oprm1 16 0.70 2.53 8.38
62 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36
63 INT117497 Positive_regulation of F2r 18 0.57 14.45 8.13
64 INT91238 Regulation of Negative_regulation of Oprm1 6 0.45 1.4 7.85
65 INT62372 Positive_regulation of Localization of Oprm1 8 0.50 0.46 7.71
66 INT103791 Positive_regulation of Positive_regulation of F2rl1 10 0.50 11.24 7.41
67 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
68 INT16628 Negative_regulation of Positive_regulation of Oprm1 9 0.43 0.89 6.92
69 INT62524 Negative_regulation of Phosphorylation of Oprm1 7 0.59 0.08 6.92
70 INT75228 Positive_regulation of Negative_regulation of Oprm1 8 0.49 0.95 6.9
71 INT139149 Binding of Gria1 22 0.37 5.71 6.88
72 INT120298 Negative_regulation of Phosphorylation of Gria1 6 0.57 8.99 6.68
73 INT5932 Regulation of Regulation of Oprm1 7 0.61 0.44 6.47
74 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
75 INT118516 Positive_regulation of Positive_regulation of F2RL1 7 0.49 4.63 6.33
76 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
77 INT53135 Positive_regulation of Localization of Oprm1 2 0.50 0 6.12
78 INT94927 Transcription of Gria1 12 0.69 3.14 5.94
79 INT112927 Negative_regulation of Localization of Oprm1 4 0.39 0.31 5.59
80 INT90848 Localization of F2rl1 23 0.80 3.15 5.2
81 INT105256 Positive_regulation of Gene_expression of F2rl1 6 0.68 10.09 4.83
82 INT90852 Gene_expression of F2r 26 0.78 5.5 4.66
83 INT98357 Binding of Gnas 11 0.41 1.87 4.35
84 INT92902 Negative_regulation of Positive_regulation of Gria1 6 0.57 1.06 4.1
85 INT105998 Protein_catabolism of Oprm1 5 0.95 0.88 4.08
86 INT88156 Regulation of Gria1 12 0.54 2.5 4.06
87 INT107860 Positive_regulation of Gene_expression of F2RL1 10 0.68 6.36 3.88
88 INT129990 Positive_regulation of Phosphorylation of Gria1 11 0.61 3.44 3.87
89 INT5929 Positive_regulation of Regulation of Oprm1 4 0.50 0.56 3.48
90 INT8731 Regulation of Localization of Oprm1 3 0.43 0.25 3.4
91 INT100729 Localization of F2RL1 7 0.75 5.29 3.37
92 INT84564 Regulation of Positive_regulation of Gria1 2 0.33 1.86 3.3
93 INT51427 Positive_regulation of Positive_regulation of Gria1 11 0.45 1.33 3.28
94 INT68812 Regulation of Regulation of Oprm1 5 0.40 0.16 3.28
95 INT46754 Localization of F2r 7 0.78 2.36 3.24
96 INT170343 Positive_regulation of Gene_expression of Gria1 10 0.61 2.77 3.09
97 INT58433 Negative_regulation of F2r 9 0.59 2.77 3.08
98 INT70377 Regulation of Transcription of Oprm1 3 0.47 0.93 2.78
99 INT224481 Regulation of F2RL1 4 0.37 5.07 2.74
100 INT161942 Regulation of Gene_expression of F2RL1 12 0.62 4.84 2.73
101 INT82653 Regulation of F2r 8 0.36 3.78 2.62
102 INT131973 Positive_regulation of Transcription of Gria1 3 0.49 0.35 2.62
103 INT111017 Regulation of F2rl1 3 0.22 0 2.61
104 INT139148 Negative_regulation of Gene_expression of Gria1 6 0.51 0.89 2.56
105 INT170350 Localization of Gria1 7 0.65 2.36 2.51
106 INT150339 Gene_expression of F2R 10 0.73 3.59 2.46
107 INT111016 Gene_expression of F2rl1 11 0.73 3.58 2.37
108 INT138331 Binding of F2rl1 4 0.36 1.92 2.32
109 INT114433 Positive_regulation of Positive_regulation of F2rl1 4 0.49 3.5 2.29
110 INT224480 Binding of F2RL1 5 0.36 5.2 2.19
111 INT82652 Negative_regulation of F2r 4 0.37 3.5 2.19
112 INT71952 Regulation of Negative_regulation of Oprm1 3 0.43 0.09 2.18
113 INT111018 Binding of F2rl1 5 0.30 3.11 2.02
114 INT224496 Negative_regulation of F2RL1 3 0.48 1.85 1.97
115 INT62522 Regulation of Phosphorylation of Oprm1 3 0.13 0 1.96
116 INT218827 Negative_regulation of Phosphorylation of Gria1 6 0.36 3.61 1.67
117 INT156231 Binding of F2r 9 0.23 3.78 1.57
118 INT130552 Negative_regulation of Localization of Oprm1 2 0.31 0.37 1.53
119 INT9953 Positive_regulation of Gnas 10 0.34 3.21 1.51
120 INT312743 Regulation of Phosphorylation of Gria1 2 0.51 2.01 1.5
121 INT123880 Positive_regulation of Positive_regulation of Gria1 3 0.15 0.7 1.48
122 INT105997 Positive_regulation of Protein_catabolism of Oprm1 2 0.66 0.41 1.45
123 INT21106 Regulation of Phosphorylation of Oprm1 3 0.61 0 1.43
124 INT96651 Negative_regulation of F2rl1 4 0.37 2.26 1.4
125 INT65179 Regulation of Regulation of Gria1 2 0.07 0.37 1.39
126 INT232603 Positive_regulation of Binding of Gria1 2 0.50 0.23 1.34
127 INT85667 Negative_regulation of Negative_regulation of Oprm1 3 0.37 0.54 1.31
128 INT119743 Negative_regulation of Positive_regulation of F2rl1 3 0.43 1.97 1.3
129 INT327936 Regulation of Gene_expression of F2rl1 1 0.61 2.62 1.26
130 INT129988 Regulation of Phosphorylation of Gria1 3 0.28 1.94 1.25
131 INT117498 Regulation of Positive_regulation of F2r 1 0.18 0.91 1.24
132 INT14138 Regulation of Localization of Oprm1 1 0.28 0 1.23
133 INT98976 Regulation of F2r 7 0.60 0.71 1.22
134 INT170347 Positive_regulation of Localization of Gria1 3 0.44 0.33 1.22
135 INT129989 Negative_regulation of Positive_regulation of Gria1 2 0.35 0.82 1.21
136 INT338033 Localization of F2r 1 0.41 0.62 1.2
137 INT129374 Negative_regulation of Regulation of Oprm1 3 0.43 0.58 1.18
138 INT224494 Regulation of Positive_regulation of F2RL1 4 0.37 1.67 1.11
139 INT159330 Positive_regulation of Localization of F2rl1 1 0.49 0.34 1.02
140 INT21108 Negative_regulation of Phosphorylation of Oprm1 2 0.43 0 0.98
141 INT112311 Regulation of F2rl1 2 0.27 0.73 0.97
142 INT224489 Negative_regulation of Gene_expression of F2RL1 3 0.57 1.51 0.96
143 INT195105 Negative_regulation of Gene_expression of F2r 3 0.37 1.41 0.91
144 INT101495 Regulation of Positive_regulation of F2rl1 1 0.26 0.88 0.91
145 INT170355 Regulation of Gene_expression of Gria1 4 0.54 0.98 0.82
146 INT123412 Negative_regulation of Transcription of Oprm1 2 0.56 0.06 0.79
147 INT195099 Positive_regulation of Gene_expression of F2r 7 0.57 5.31 0.78
148 INT215783 Localization of Gnas 1 0.12 1.64 0.76
149 INT353325 Positive_regulation of Localization of F2r 1 0.49 1.31 0.76
150 INT55921 Negative_regulation of Transcription of Oprm1 1 0.43 0 0.76
151 INT62192 Regulation of Localization of F2r 2 0.60 0.59 0.7
152 INT129375 Negative_regulation of Regulation of Oprm1 1 0.28 0.49 0.68
153 INT296440 Regulation of Binding of Gria1 1 0.16 1.14 0.66
154 INT292595 Negative_regulation of Positive_regulation of F2RL1 3 0.40 1.29 0.63
155 INT100730 Positive_regulation of Localization of F2RL1 2 0.49 0.99 0.62
156 INT207089 Regulation of Negative_regulation of F2r 1 0.17 1.49 0.62
157 INT353321 Regulation of Positive_regulation of F2r 1 0.60 0.6 0.62
158 INT257798 Transcription of Gria1 1 0.18 0.4 0.61
159 INT297831 Protein_catabolism of F2rl1 2 0.10 0.5 0.6
160 INT123672 Positive_regulation of F2R 9 0.47 0.77 0.58
161 INT200893 Negative_regulation of Transcription of Gria1 2 0.08 0.6 0.58
162 INT259171 Protein_catabolism of Gria1 1 0.76 0.48 0.58
163 INT191777 Binding of F2r 2 0.02 0.89 0.54
164 INT124290 Negative_regulation of Gene_expression of F2rl1 3 0.42 1.48 0.52
165 INT338026 Regulation of Localization of F2r 1 0.25 0.05 0.52
166 INT111019 Negative_regulation of Binding of F2rl1 1 0.35 0 0.48
167 INT81357 Regulation of Negative_regulation of Gnas 1 0.02 0.1 0.47
168 INT149198 Positive_regulation of Regulation of Oprm1 2 0.47 0.23 0.42
169 INT156226 Transcription of F2rl1 1 0.23 1.25 0.41
170 INT166066 Negative_regulation of Localization of F2rl1 1 0.43 0.47 0.4
171 INT156230 Positive_regulation of Binding of F2rl1 1 0.21 1.11 0.4
172 INT112310 Negative_regulation of Regulation of F2rl1 1 0.03 0 0.39
173 INT292591 Negative_regulation of Negative_regulation of F2RL1 1 0.35 0 0.36
174 INT144981 Binding of F2R 3 0.36 1.66 0.35
175 INT353324 Negative_regulation of Positive_regulation of F2r 1 0.41 0.24 0.35
176 INT18041 Protein_catabolism of Oprm1 1 0.87 0 0.31
177 INT224491 Transcription of F2RL1 1 0.68 0.31 0.26
178 INT94657 Transcription of F2rl1 1 0.69 0.5 0.26
179 INT105257 Regulation of Localization of F2rl1 1 0.23 0 0.26
180 INT62191 Negative_regulation of Localization of F2r 1 0.35 0 0.26
181 INT195091 Negative_regulation of Positive_regulation of F2r 1 0.48 1.69 0.25
182 INT316938 Negative_regulation of Regulation of Gria1 1 0.32 0.23 0.24
183 INT305682 Positive_regulation of Positive_regulation of F2r 1 0.03 0 0.24
184 INT200897 Negative_regulation of Localization of Gria1 1 0.07 0 0.22
185 INT208539 Positive_regulation of Gene_expression of Gnas 4 0.08 2.76 0.18
186 INT195112 Positive_regulation of Positive_regulation of F2r 1 0.41 0.97 0.18
187 INT207129 Localization of F2rl1 1 0.22 0.72 0.18
188 INT257804 Regulation of Localization of Gria1 1 0.15 0.7 0.16
189 INT261745 Regulation of F2R 1 0.43 0.22 0.16
190 INT261739 Regulation of Gene_expression of F2R 1 0.26 0.22 0.16
191 INT98700 Regulation of Gene_expression of F2r 1 0.45 0 0.15
192 INT292590 Positive_regulation of Negative_regulation of F2RL1 1 0.38 0 0.15
193 INT207087 Negative_regulation of Binding of F2r 1 0.27 0.06 0.14
194 INT313103 Positive_regulation of Regulation of Gria1 1 0.02 0.29 0.13
195 INT341581 Positive_regulation of Transcription of F2RL1 1 0.44 0 0.11
196 INT307530 Negative_regulation of Binding of F2R 1 0.03 0 0.09
197 INT107569 Transcription of Gnas 1 0.01 0 0.08
198 INT145503 Protein_catabolism of F2r 1 0.66 0.46 0.07
199 INT195082 Regulation of Gene_expression of F2r 1 0.37 0.67 0.07
200 INT292586 Phosphorylation of F2RL1 1 0.51 0 0.07
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