GO:0031687

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Name A2A adenosine receptor binding
Categary Function
Go Slim No
Go Link GO:0031687
Unique Molecular Interactions 25
Total Molecular Interactions 53
Total Single Events 392
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for A2A adenosine receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for A2A adenosine receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
2 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
3 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
4 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
5 INT162250 Binding of TRPV1 and Grm5 1 0.01 0.8 1.03
6 INT157522 GRM5 Regulation of Gene_expression of OPRM1 1 0.28 0 0.97
7 INT210979 Grm5 Positive_regulation of Cysltr1 1 0.00 0.76 0.75
8 INT168911 Grm5 Regulation of Mapk3 1 0.17 0.78 0.71
9 INT282141 Grm5 Regulation of Grip2 1 0.00 0.61 0.69
10 INT148173 Positive_regulation of Grm5 Positive_regulation of Phosphorylation of Mapk1 1 0.01 0.45 0.65
11 INT107523 Negative_regulation of Grm5 Negative_regulation of Gene_expression of Fos 1 0.37 0.09 0.58
12 INT159774 Binding of GRM5 and TRPV1 1 0.40 0.5 0.51
13 INT8181 Grm5 Positive_regulation of Gh 1 0.00 0 0.44
14 INT343640 Positive_regulation of Grm5 Positive_regulation of Adp 1 0.01 0 0.4
15 INT150196 Grm5 Regulation of Grin2b 1 0.45 0 0.36
16 INT170727 Binding of Grm5 and Calm2 1 0.01 0.13 0.28
17 INT170719 Binding of Grm5 and Siah1a 1 0.01 1.1 0.28
18 INT264841 NAMPT Positive_regulation of GRM5 1 0.01 0.72 0.27
19 INT343641 Grm5 Positive_regulation of Adp 1 0.01 0 0.19
20 INT343644 Grm5 Positive_regulation of Cav2 1 0.05 0 0.19
21 INT265982 Homer1 Regulation of Grm5 1 0.04 0.38 0.12
22 INT347802 Grm5 Positive_regulation of Oss1 1 0.12 0.67 0.11
23 INT265981 Homer1 Regulation of Localization of Grm5 1 0.04 0.06 0.09
24 INT343645 Positive_regulation of Grm5 Positive_regulation of Localization of Car2 1 0.03 0 0
25 INT170726 Negative_regulation of Binding of Grm5 and Calm2 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for A2A adenosine receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in A2A adenosine receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95789 Positive_regulation of Grm5 42 0.55 20.1 33.72
2 INT51602 Gene_expression of Grm5 59 0.75 17.29 26.99
3 INT78571 Positive_regulation of Grm5 35 0.69 11.81 22.45
4 INT94650 Gene_expression of Grm5 32 0.77 11.26 14.82
5 INT107522 Regulation of Grm5 9 0.44 6.42 11.46
6 INT78570 Negative_regulation of Grm5 15 0.57 5.45 9.17
7 INT107657 Positive_regulation of Positive_regulation of Grm5 6 0.69 1.83 8.92
8 INT147498 Gene_expression of GRM5 10 0.75 3.16 7.12
9 INT119132 Regulation of Grm5 8 0.48 2.66 5.46
10 INT107655 Positive_regulation of Gene_expression of Grm5 6 0.67 5.09 5.06
11 INT107390 Negative_regulation of Grm5 11 0.45 6 4.42
12 INT74815 Binding of Grm5 11 0.36 3.62 4.25
13 INT95784 Positive_regulation of Positive_regulation of Grm5 8 0.11 3.48 4.01
14 INT140206 Binding of GRM5 6 0.36 1.85 2.52
15 INT123713 Binding of Grm5 7 0.31 2.96 2.38
16 INT107656 Regulation of Gene_expression of Grm5 4 0.26 0.84 2.38
17 INT157529 Positive_regulation of GRM5 3 0.48 0.59 2.07
18 INT152025 Negative_regulation of Positive_regulation of Grm5 4 0.14 2.21 2.06
19 INT101945 Regulation of Gene_expression of Grm5 2 0.48 0.96 1.98
20 INT51603 Localization of Grm5 5 0.73 0.33 1.87
21 INT147384 Regulation of Positive_regulation of Grm5 2 0.11 0.41 1.65
22 INT117607 Localization of Grm5 12 0.50 1.31 1.56
23 INT100523 Regulation of GRM5 2 0.26 0.49 1.51
24 INT128391 Positive_regulation of Regulation of Grm5 1 0.37 0 1.49
25 INT168906 Positive_regulation of Gene_expression of Grm5 4 0.39 1.75 1.38
26 INT107658 Regulation of Positive_regulation of Grm5 1 0.26 0.84 1.17
27 INT157528 Regulation of Gene_expression of GRM5 1 0.43 0 0.96
28 INT223653 Transcription of Grm5 4 0.69 1.4 0.83
29 INT157526 Regulation of Binding of GRM5 1 0.43 0 0.73
30 INT168907 Negative_regulation of Negative_regulation of Grm5 1 0.14 1.01 0.65
31 INT210972 Positive_regulation of Localization of Grm5 3 0.06 0.24 0.48
32 INT163205 Transcription of Grm5 1 0.00 0.73 0.47
33 INT128595 Negative_regulation of Gene_expression of Grm5 2 0.38 0.51 0.43
34 INT347792 Regulation of Regulation of Grm5 1 0.35 0.12 0.42
35 INT147500 Positive_regulation of Gene_expression of GRM5 1 0.67 0.25 0.33
36 INT147499 Negative_regulation of Gene_expression of GRM5 1 0.41 0.29 0.26
37 INT170678 Negative_regulation of Gene_expression of Grm5 1 0.41 0.07 0.09
38 INT223648 Negative_regulation of Transcription of Grm5 1 0.41 0.65 0.08
39 INT347712 Positive_regulation of Binding of Grm5 1 0.13 0 0.05
40 INT170708 Protein_catabolism of Grm5 1 0.02 0.08 0
41 INT170703 Positive_regulation of Regulation of Grm5 1 0.01 0 0
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