GO:0031698

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Name beta-2 adrenergic receptor binding
Categary Function
Go Slim No
Go Link GO:0031698
Unique Molecular Interactions 91
Total Molecular Interactions 139
Total Single Events 1206
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for beta-2 adrenergic receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for beta-2 adrenergic receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
2 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
3 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
4 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
5 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
6 INT281089 Binding of Gria1 and Ltp 1 0.25 0.6 0.9
7 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83
8 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
9 INT232621 Binding of Gria1 and Psd 1 0.10 0.29 0.77
10 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73
11 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71
12 INT51433 Gria1 Positive_regulation of Eif3g 1 0.03 0 0.7
13 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
14 INT281083 Binding of Gria1 and Gipc1 1 0.01 0 0.65
15 INT296463 Binding of Gria1 and Pick1 1 0.16 0.32 0.59
16 INT296456 Gria1 Negative_regulation of Rbm39 1 0.00 0.45 0.57
17 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
18 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
19 INT281087 Binding of Gria1 and Hmmr 1 0.04 0 0.55
20 INT312751 Phosphorylation of Gria1 Positive_regulation of GRIA1 1 0.18 0.22 0.55
21 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54
22 INT311521 Gnrhr Positive_regulation of Gene_expression of Gria1 1 0.00 0.54 0.54
23 INT311522 Gnrhr Positive_regulation of Transcription of Gria1 1 0.00 0.54 0.54
24 INT232618 Gene_expression of Grid2ip Regulation of Localization of Gria1 1 0.28 0.86 0.52
25 INT349130 Phosphorylation of Gria1 Positive_regulation of Shisa9 1 0.00 0.49 0.52
26 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
27 INT296457 Camk2a Positive_regulation of Phosphorylation of Gria1 1 0.19 0.28 0.49
28 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
29 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49
30 INT232619 Binding of Gria1 and Grid2ip 1 0.23 0.51 0.48
31 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
32 INT168699 Binding of Nedd4 and Tyr 1 0.02 0.45 0.46
33 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
34 INT86069 Positive_regulation of Gria1 Positive_regulation of Gene_expression of Fos 1 0.11 0.3 0.42
35 INT127543 Gria1 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42
36 INT74713 Binding of Gria1 and Olr1868 1 0.00 0 0.42
37 INT127546 Gria1 Positive_regulation of Gene_expression of Kcnab3 1 0.02 0.35 0.42
38 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
39 INT296459 Binding of Dlg1 and Gria1 1 0.02 0.23 0.31
40 INT296453 Binding of Gria1 and Mpdz 1 0.02 0.23 0.31
41 INT103482 RARB Positive_regulation of Gene_expression of Gria1 1 0.00 0 0.27
42 INT103483 BDNF Positive_regulation of Gene_expression of Gria1 1 0.03 0 0.26
43 INT51432 Gria1 Positive_regulation of Trib3 1 0.04 0 0.25
44 INT273109 Bdnf Positive_regulation of Gene_expression of Gria1 1 0.66 0.07 0.24
45 INT296467 Binding of Cacng2 and Gria1 1 0.12 0.25 0.23
46 INT218832 Ppp1r9a Regulation of Phosphorylation of Gria1 1 0.15 0.66 0.23
47 INT296449 Binding of Gria1 and Tinagl1 1 0.08 0.25 0.23
48 INT311527 Binding of Grin2a and Gria1 1 0.01 0 0.21
49 INT170366 Gria1 Regulation of Phosphorylation of Camk2a 1 0.23 0.07 0.18
50 INT256987 Binding of Cd81 and Slc9a3r1 1 0.43 0.06 0.17
51 INT243772 Safb Negative_regulation of Gria1 1 0.23 0.84 0.17
52 INT168700 Positive_regulation of Binding of Nedd4 and Tyr 1 0.03 0.19 0.17
53 INT273097 Binding of Bdnf and Gria1 1 0.39 0.17 0.16
54 INT311526 Gria1 Regulation of Gene_expression of Grin2a 1 0.01 0.32 0.15
55 INT204497 Fmr1 Regulation of Positive_regulation of Gria1 1 0.04 1.75 0.14
56 INT263752 Binding of Gria1 and Igh-Lev 1 0.00 0 0.11
57 INT273108 Gria1 Regulation of Positive_regulation of Gria2 1 0.04 0.09 0.1
58 INT255289 Snap25 Regulation of Gene_expression of Gnas 1 0.00 0 0.09
59 INT284303 Mir155 Negative_regulation of Gnas 1 0.00 0.49 0.08
60 INT273104 Mtor Negative_regulation of Gene_expression of Gria1 1 0.46 0.15 0.08
61 INT273115 Bdnf Negative_regulation of Gene_expression of Gria1 1 0.47 0.15 0.08
62 INT218834 Ppp1cc Regulation of Phosphorylation of Gria1 1 0.19 0.66 0.07
63 INT218829 Ppp1cc Regulation of Phosphorylation of Gria1 1 0.20 0.63 0.07
64 INT346752 Binding of Dlg1 and Gria1 1 0.02 0 0.06
65 INT218830 Camk2a Regulation of Phosphorylation of Gria1 1 0.36 0.63 0.06
66 INT273102 Bdnf Regulation of Gria1 1 0.30 0.08 0.03
67 INT273095 Rbm14 Regulation of Gria1 1 0.00 0.07 0.03
68 INT273105 Mtor Regulation of Gria1 1 0.29 0.07 0.03
69 INT256997 Binding of RLBP1 and Slc9a3r1 1 0.44 0 0
70 INT284304 Binding of Adrb3 and Gnas 1 0.00 0.23 0
71 INT329013 Binding of LITAF and Nedd4 1 0.15 1.4 0
72 INT284302 Mir155 Regulation of Gnas 1 0.00 0.64 0
73 INT256979 Binding of Slc9a3r1 and Rlbp1 1 0.03 0 0
74 INT329012 Binding of MPZ and Nedd4 1 0.03 0.7 0
75 INT256980 Binding of Slc9a3r1 and Rpe 1 0.08 0.13 0
76 INT256992 Binding of Slc9a3r1 and Hspb6 1 0.09 0 0
77 INT231169 Gnas Positive_regulation of Gene_expression of Dmd 1 0.00 0.19 0
78 INT256981 Binding of Dlg1 and Slc9a3r1 1 0.22 0 0
79 INT283201 Gm4658 Regulation of Gnas 1 0.00 0.56 0
80 INT256989 Binding of Ezr and Slc9a3r1 1 0.10 0 0
81 INT325836 Binding of Dnm2 and Gnas 1 0.00 0.22 0
82 INT325839 Binding of Dnm1 and Gnas 1 0.00 0.11 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for beta-2 adrenergic receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in beta-2 adrenergic receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
2 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
3 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
4 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
5 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78
6 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
7 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02
8 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
9 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
10 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
11 INT49538 Binding of Gria1 22 0.47 2.66 13.35
12 INT111948 Positive_regulation of Gria1 23 0.61 7.55 12.03
13 INT8072 Localization of Gria1 17 0.75 2.62 10.04
14 INT96298 Negative_regulation of Gria1 25 0.57 10.61 9.7
15 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
16 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
17 INT139149 Binding of Gria1 22 0.37 5.71 6.88
18 INT120298 Negative_regulation of Phosphorylation of Gria1 6 0.57 8.99 6.68
19 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
20 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
21 INT94927 Transcription of Gria1 12 0.69 3.14 5.94
22 INT98357 Binding of Gnas 11 0.41 1.87 4.35
23 INT92902 Negative_regulation of Positive_regulation of Gria1 6 0.57 1.06 4.1
24 INT88156 Regulation of Gria1 12 0.54 2.5 4.06
25 INT129990 Positive_regulation of Phosphorylation of Gria1 11 0.61 3.44 3.87
26 INT84564 Regulation of Positive_regulation of Gria1 2 0.33 1.86 3.3
27 INT51427 Positive_regulation of Positive_regulation of Gria1 11 0.45 1.33 3.28
28 INT170343 Positive_regulation of Gene_expression of Gria1 10 0.61 2.77 3.09
29 INT131973 Positive_regulation of Transcription of Gria1 3 0.49 0.35 2.62
30 INT139148 Negative_regulation of Gene_expression of Gria1 6 0.51 0.89 2.56
31 INT170350 Localization of Gria1 7 0.65 2.36 2.51
32 INT218827 Negative_regulation of Phosphorylation of Gria1 6 0.36 3.61 1.67
33 INT9953 Positive_regulation of Gnas 10 0.34 3.21 1.51
34 INT312743 Regulation of Phosphorylation of Gria1 2 0.51 2.01 1.5
35 INT123880 Positive_regulation of Positive_regulation of Gria1 3 0.15 0.7 1.48
36 INT65179 Regulation of Regulation of Gria1 2 0.07 0.37 1.39
37 INT232603 Positive_regulation of Binding of Gria1 2 0.50 0.23 1.34
38 INT129988 Regulation of Phosphorylation of Gria1 3 0.28 1.94 1.25
39 INT170347 Positive_regulation of Localization of Gria1 3 0.44 0.33 1.22
40 INT129989 Negative_regulation of Positive_regulation of Gria1 2 0.35 0.82 1.21
41 INT170355 Regulation of Gene_expression of Gria1 4 0.54 0.98 0.82
42 INT215783 Localization of Gnas 1 0.12 1.64 0.76
43 INT296440 Regulation of Binding of Gria1 1 0.16 1.14 0.66
44 INT257798 Transcription of Gria1 1 0.18 0.4 0.61
45 INT130971 Binding of Slc9a3r1 2 0.39 0.32 0.59
46 INT200893 Negative_regulation of Transcription of Gria1 2 0.08 0.6 0.58
47 INT259171 Protein_catabolism of Gria1 1 0.76 0.48 0.58
48 INT81357 Regulation of Negative_regulation of Gnas 1 0.02 0.1 0.47
49 INT130969 Positive_regulation of Binding of Slc9a3r1 1 0.09 0.26 0.43
50 INT168697 Binding of Nedd4 1 0.26 0.48 0.38
51 INT130972 Gene_expression of Slc9a3r1 2 0.63 0.36 0.37
52 INT316938 Negative_regulation of Regulation of Gria1 1 0.32 0.23 0.24
53 INT200897 Negative_regulation of Localization of Gria1 1 0.07 0 0.22
54 INT168693 Negative_regulation of Binding of Nedd4 1 0.31 0.29 0.21
55 INT168696 Positive_regulation of Binding of Nedd4 1 0.34 0.29 0.21
56 INT208539 Positive_regulation of Gene_expression of Gnas 4 0.08 2.76 0.18
57 INT257804 Regulation of Localization of Gria1 1 0.15 0.7 0.16
58 INT313103 Positive_regulation of Regulation of Gria1 1 0.02 0.29 0.13
59 INT107569 Transcription of Gnas 1 0.01 0 0.08
60 INT354954 Negative_regulation of Regulation of Gria1 1 0.27 0.16 0.06
61 INT277277 Regulation of Gene_expression of Gnas 2 0.00 0.33 0.04
62 INT354956 Negative_regulation of Localization of Gria1 1 0.26 0 0
63 INT256965 Positive_regulation of Slc9a3r1 1 0.38 0 0
64 INT202870 Negative_regulation of Negative_regulation of Gnas 1 0.01 0.53 0
65 INT202861 Positive_regulation of Negative_regulation of Gnas 1 0.01 0.39 0
66 INT256950 Negative_regulation of Gene_expression of Slc9a3r1 1 0.35 0 0
67 INT256962 Positive_regulation of Gene_expression of Slc9a3r1 1 0.38 0 0
68 INT256968 Localization of Slc9a3r1 1 0.57 0 0
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