GO:0031702

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Name type 1 angiotensin receptor binding
Categary Function
Go Slim No
Go Link GO:0031702
Unique Molecular Interactions 448
Total Molecular Interactions 607
Total Single Events 3761
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for type 1 angiotensin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for type 1 angiotensin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
2 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
3 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
4 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
5 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
6 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
7 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
8 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
9 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
10 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
11 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
12 INT299985 BDKRB2 Regulation of Gene_expression of BDKRB1 1 0.21 0.75 1.16
13 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
14 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
15 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
16 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
17 INT299986 BDKRB2 Regulation of Gene_expression of SPANXB1 1 0.29 0.51 1.02
18 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
19 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
20 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
21 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
22 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
23 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
24 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
25 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
26 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
27 INT299990 BDKRB2 Positive_regulation of TRPV1 1 0.43 0.74 0.84
28 INT139745 Positive_regulation of Binding of Oprm1 and Arrb2 1 0.28 0.14 0.81
29 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
30 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
31 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
32 INT150643 Binding of Bdkrb2 and Trpa1 1 0.36 0.55 0.78
33 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
34 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
35 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
36 INT140790 Positive_regulation of Ptger3 Negative_regulation of Negative_regulation of Bdkrb2 1 0.00 0.07 0.76
37 INT148909 Binding of GNA13 and TP53INP2 1 0.06 0.31 0.73
38 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
39 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
40 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
41 INT47145 Penk Negative_regulation of Agt 1 0.06 0 0.66
42 INT162878 Agt Regulation of Ang 1 0.21 1.15 0.66
43 INT153921 Positive_regulation of Adra2a Regulation of Ednrb 1 0.01 0 0.66
44 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
45 INT121460 KNG1 Positive_regulation of Bdkrb2 1 0.08 0.44 0.62
46 INT57421 Oprd1 Regulation of Agt 1 0.29 0 0.62
47 INT121459 Bdkrb2 Positive_regulation of KNG1 1 0.09 0.44 0.62
48 INT121453 Bdkrb2 Positive_regulation of Trpv1 1 0.28 0.42 0.6
49 INT56116 Agt Positive_regulation of Lhb 1 0.15 0 0.58
50 INT254637 Bdkrb2 Regulation of Gene_expression of Ccl5 1 0.17 1.22 0.56
51 INT56117 Agt Positive_regulation of Positive_regulation of CGA 1 0.00 0 0.56
52 INT126641 Binding of KNG1 and Bdkrb2 1 0.11 0.42 0.55
53 INT73367 Agt Negative_regulation of Localization of Calca 1 0.43 0.26 0.54
54 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
55 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
56 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53
57 INT130157 Pomc Regulation of Gene_expression of Ednrb 1 0.14 0 0.52
58 INT303722 KNG1 Positive_regulation of Bdkrb2 1 0.01 0.7 0.52
59 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
60 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
61 INT254638 Bdkrb2 Positive_regulation of Positive_regulation of Bdkrb1 1 0.09 0.96 0.48
62 INT39078 Binding of Agt and Penk 1 0.24 0.42 0.48
63 INT47144 Negative_regulation of Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
64 INT47146 Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
65 INT80116 Binding of C4orf6 and Bdkrb2 1 0.41 0.18 0.47
66 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
67 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
68 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
69 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
70 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
71 INT39077 Agt Negative_regulation of Prss12 1 0.05 0.44 0.46
72 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
73 INT151958 Negative_regulation of Agt Positive_regulation of Agtrap 1 0.39 0 0.44
74 INT151959 Agt Positive_regulation of Agtrap 1 0.63 0 0.44
75 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
76 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43
77 INT254636 Bdkrb2 Regulation of Gene_expression of Ccl2 1 0.15 1.15 0.43
78 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
79 INT36459 Binding of Agt and Positive_regulation of Localization of Avp 1 0.38 0.19 0.43
80 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
81 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
82 INT85511 Binding of KNG1 and Bdkrb2 1 0.54 0.51 0.4
83 INT36460 Binding of Agt and Avp 1 0.28 0.16 0.4
84 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
85 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
86 INT64384 Agt Negative_regulation of Son 1 0.26 0 0.39
87 INT332701 Binding of BDKRB1 and BDKRB2 1 0.01 0.5 0.39
88 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
89 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
90 INT330120 Bdkrb2 Regulation of Bdkrb1 1 0.19 1.26 0.38
91 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
92 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
93 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
94 INT143914 Binding of Rbm39 and Arrb2 1 0.03 0.07 0.37
95 INT39092 Agt Negative_regulation of Ren 1 0.39 0 0.37
96 INT152315 Ifng Regulation of Ednrb 1 0.19 0.22 0.36
97 INT152313 Il18 Regulation of Ednrb 1 0.30 0.22 0.36
98 INT53257 CALCRL Negative_regulation of Binding of Agt 1 0.00 0 0.36
99 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
100 INT44112 Agt Regulation of Penk 1 0.08 0 0.35
101 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
102 INT4638 Binding of Agt and Adarb1 3 0.01 0 0.34
103 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34
104 INT136008 Binding of BDKRB2 and INSRR 1 0.01 0.17 0.34
105 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34
106 INT162157 Binding of SGCG and Agt 1 0.33 0.35 0.33
107 INT147436 Agt Positive_regulation of Gene_expression of Ros1 1 0.02 0.5 0.33
108 INT242995 Agt Positive_regulation of Spp1 1 0.36 1.82 0.33
109 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
110 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32
111 INT201484 Negative_regulation of Prkcg Negative_regulation of Positive_regulation of Ednrb 1 0.34 0.96 0.32
112 INT44127 Agt Negative_regulation of DSPP 1 0.02 0 0.32
113 INT337327 KNG1 Positive_regulation of BDKRB2 1 0.21 0.4 0.32
114 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
115 INT56115 Agt Regulation of Lhb 1 0.16 0 0.32
116 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31
117 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
118 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28
119 INT116853 Chdh Regulation of Positive_regulation of Agt 1 0.11 0.19 0.28
120 INT45541 Agt Positive_regulation of Lnpep 1 0.03 0 0.27
121 INT45545 Agt Positive_regulation of Oxt 1 0.23 0 0.27
122 INT126550 Agt Positive_regulation of Gene_expression of Nsfl1c 1 0.39 1.07 0.26
123 INT242991 Agt Positive_regulation of Gene_expression of Spp1 1 0.21 0.66 0.26
124 INT9528 Agt Positive_regulation of Localization of Pomc 2 0.50 0.14 0.25
125 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
126 INT126547 Agt Positive_regulation of Nfkb1 1 0.46 0.99 0.25
127 INT126548 Negative_regulation of Agt Positive_regulation of Nfkb1 1 0.29 0.99 0.25
128 INT297258 Binding of Agt and Agtr2 1 0.23 0.7 0.25
129 INT126553 Agt Positive_regulation of Nfkb1 1 0.06 0.99 0.25
130 INT256028 Binding of Agt and Lnpep 1 0.19 1.16 0.24
131 INT41588 Binding of AGT and Lhb 1 0.00 0 0.24
132 INT41589 Binding of AGT and Prl 1 0.00 0 0.24
133 INT126551 Agt Positive_regulation of Gene_expression of Ptgs1 1 0.25 0.92 0.24
134 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
135 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
136 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
137 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21
138 INT222566 Agt Positive_regulation of Localization of Prl 1 0.08 0.23 0.21
139 INT229360 Agt Positive_regulation of Agtr1a 2 0.48 1.26 0.2
140 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 0.04 1.44 0.2
141 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
142 INT249993 Binding of Agt and Igkv4-55 1 0.02 0.49 0.2
143 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19
144 INT184540 Agt Regulation of Gene_expression of Ccl2 1 0.08 1.66 0.18
145 INT41978 Binding of Agt and Htr1a 1 0.41 0.54 0.18
146 INT229223 Binding of AGT and FAS 1 0.08 0.91 0.17
147 INT36568 AGT Positive_regulation of FBF1 1 0.39 0.5 0.17
148 INT269333 Binding of BDKRB2 and NOS3 1 0.02 0 0.17
149 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17
150 INT229224 Positive_regulation of Binding of AGT and FAS 1 0.09 0.92 0.17
151 INT36567 Negative_regulation of AGT Positive_regulation of FBF1 1 0.36 0.5 0.17
152 INT111863 Negative_regulation of Binding of AGT and LNPEP 1 0.09 0 0.16
153 INT264276 Binding of Ednrb and P2rx1 1 0.00 0.17 0.16
154 INT111861 Binding of AGT and LNPEP 1 0.07 0 0.16
155 INT21509 Agt Regulation of Edn1 1 0.53 0 0.15
156 INT242400 Binding of Bdkrb2 and Ros1 1 0.02 0.84 0.15
157 INT72817 Agt Negative_regulation of Avp 1 0.07 0.34 0.14
158 INT347071 Negative_regulation of REN Negative_regulation of Positive_regulation of AGT 1 0.35 0.44 0.14
159 INT34430 AGT Positive_regulation of Localization of POMC 1 0.30 0.31 0.14
160 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14
161 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14
162 INT89940 Ednrb Positive_regulation of Positive_regulation of TNF 1 0.01 0.09 0.14
163 INT293115 Agt Regulation of Positive_regulation of Crh 1 0.16 0.37 0.14
164 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14
165 INT293123 Agtr1a Regulation of Negative_regulation of Agt 1 0.14 0.25 0.14
166 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
167 INT33749 Crh Positive_regulation of Localization of Agt 1 0.31 0 0.13
168 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
169 INT89939 Ednrb Regulation of Gene_expression of TNF 1 0.00 0.09 0.13
170 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
171 INT59810 ADRA1D Positive_regulation of AGT 1 0.01 0 0.13
172 INT351974 Agt Positive_regulation of Gene_expression of Stk11 1 0.51 11.1 0.12
173 INT107226 Agt Positive_regulation of AFF1 1 0.01 0 0.12
174 INT44974 Agt Positive_regulation of Gene_expression of Ptger2 1 0.02 0.42 0.12
175 INT33750 Apoa2 Regulation of Agt 1 0.07 0 0.12
176 INT182496 AGT Positive_regulation of Phosphorylation of STAT3 1 0.03 0.79 0.12
177 INT345290 AGT Positive_regulation of NOX1 1 0.00 1.11 0.12
178 INT229359 Agt Positive_regulation of Binding of Agtr1a 1 0.25 0.9 0.12
179 INT119157 Agt Positive_regulation of Positive_regulation of Agtr2 1 0.06 0 0.11
180 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11
181 INT222503 Agt Positive_regulation of Localization of Gh1 1 0.02 0.23 0.11
182 INT188358 Binding of Csf2 and Positive_regulation of Jak2 1 0.34 0.19 0.11
183 INT169340 Binding of UGT8 and Jak2 1 0.36 0.15 0.11
184 INT300306 Agt Positive_regulation of Mapk14 1 0.14 1.51 0.11
185 INT256023 Lnpep Regulation of Gene_expression of Agt 1 0.18 0.14 0.1
186 INT46502 Agt Positive_regulation of Odc1 1 0.18 0 0.1
187 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1
188 INT336990 Binding of AGTR1 and BDKRB2 1 0.03 0 0.1
189 INT148102 AGT Positive_regulation of Gene_expression of STK24 1 0.37 0.96 0.1
190 INT10906 Agt Regulation of Localization of Nppb 1 0.10 0.19 0.1
191 INT171164 Agt Regulation of Positive_regulation of Rorb 1 0.02 0.64 0.1
192 INT256029 Lnpep Regulation of Agt 1 0.18 0.14 0.1
193 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1
194 INT257870 Agt Positive_regulation of Akt1 2 0.18 1.5 0.09
195 INT256018 Agt Positive_regulation of Oxt 1 0.12 0.31 0.09
196 INT254641 CGA Positive_regulation of AGT 1 0.17 1.51 0.08
197 INT354753 Ren Regulation of Agt 1 0.14 0.98 0.08
198 INT137632 Rasa1 Regulation of Ednrb 1 0.05 0 0.08
199 INT267969 Binding of AGT and TRPV1 1 0.00 0.44 0.08
200 INT267970 Negative_regulation of Binding of AGT and TRPV1 1 0.00 0.44 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for type 1 angiotensin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in type 1 angiotensin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
2 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
3 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
4 INT1158 Regulation of Agt 106 0.61 29.4 30.29
5 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
6 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
7 INT6848 Gene_expression of BDKRB2 40 0.75 17.19 20.04
8 INT67975 Gene_expression of Bdkrb2 38 0.68 21.69 17.94
9 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
10 INT2066 Localization of Agt 56 0.80 9.95 16.25
11 INT37803 Positive_regulation of Bdkrb2 18 0.68 14.21 13.99
12 INT3962 Regulation of AGT 50 0.62 20.96 13.01
13 INT85510 Positive_regulation of Bdkrb2 23 0.70 12.08 12.68
14 INT4199 Binding of Agt 76 0.48 21.06 12.66
15 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
16 INT66718 Positive_regulation of BDKRB2 21 0.64 9.89 11.6
17 INT398 Localization of AGT 45 0.78 16.97 11.54
18 INT88223 Gene_expression of Bdkrb2 17 0.69 13.94 11.44
19 INT8065 Binding of AGT 54 0.48 20.54 10.85
20 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68
21 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
22 INT9573 Regulation of Bdkrb2 9 0.43 6.04 8.41
23 INT100079 Positive_regulation of Gene_expression of Arrb2 7 0.63 2.26 6.77
24 INT65295 Negative_regulation of Bdkrb2 9 0.37 6.36 6.49
25 INT94979 Regulation of Arrb2 6 0.54 0.51 6.45
26 INT78178 Gene_expression of Ednrb 21 0.75 7.1 6.37
27 INT94986 Positive_regulation of Arrb2 5 0.61 1.3 6.24
28 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
29 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
30 INT83095 Regulation of Gene_expression of BDKRB2 2 0.59 4.06 5.39
31 INT85685 Gene_expression of Arrb2 5 0.74 0.66 5.13
32 INT48277 Regulation of BDKRB2 9 0.59 2.69 5.05
33 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
34 INT85681 Negative_regulation of Arrb2 5 0.47 0.79 4.71
35 INT70137 Regulation of Bdkrb2 10 0.27 5.45 4.62
36 INT29519 Gene_expression of Ednrb 8 0.66 1.99 4.55
37 INT92133 Negative_regulation of Ednrb 8 0.42 1.7 4.44
38 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
39 INT108935 Transcription of Arrb2 5 0.59 0.5 4.38
40 INT92797 Regulation of Arrb2 4 0.44 0.81 4.28
41 INT94985 Regulation of Gene_expression of Arrb2 2 0.40 0.43 4.2
42 INT152312 Positive_regulation of Ednrb 7 0.49 1.46 4.04
43 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
44 INT88221 Positive_regulation of Gene_expression of Bdkrb2 5 0.36 3.35 3.91
45 INT85679 Binding of Arrb2 4 0.39 0.79 3.82
46 INT114750 Negative_regulation of Gene_expression of Bdkrb2 4 0.17 2.68 3.64
47 INT128679 Negative_regulation of Bdkrb2 7 0.35 6.78 3.54
48 INT94983 Negative_regulation of Arrb2 2 0.52 0.26 3.47
49 INT53347 Localization of BDKRB2 5 0.75 4.96 3.39
50 INT84222 Regulation of Ednrb 4 0.45 2.24 3.25
51 INT88220 Transcription of Bdkrb2 6 0.65 3.08 3.21
52 INT66720 Negative_regulation of BDKRB2 5 0.57 1.92 3.11
53 INT85682 Positive_regulation of Arrb2 4 0.46 0.22 3.05
54 INT53348 Binding of BDKRB2 7 0.37 2.85 3
55 INT126636 Binding of Bdkrb2 3 0.33 2.18 2.78
56 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
57 INT128774 Regulation of Gene_expression of Ednrb 3 0.46 1 2.56
58 INT88222 Positive_regulation of Transcription of Bdkrb2 3 0.47 1.32 2.51
59 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
60 INT148071 Gene_expression of Agt 42 0.74 44.9 2.43
61 INT4270 Negative_regulation of Negative_regulation of Agt 10 0.43 1.08 2.43
62 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
63 INT108937 Negative_regulation of Transcription of Arrb2 1 0.38 0.31 2.31
64 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
65 INT10201 Positive_regulation of Localization of Agt 8 0.50 0.97 2.21
66 INT78177 Negative_regulation of Gene_expression of Ednrb 4 0.41 1.04 2.16
67 INT108939 Regulation of Transcription of Arrb2 1 0.24 0.19 2.1
68 INT12005 Negative_regulation of Localization of Agt 6 0.57 1.49 2.06
69 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
70 INT79915 Positive_regulation of Agt 27 0.56 12.97 1.96
71 INT12801 Negative_regulation of Regulation of Agt 4 0.43 1.2 1.96
72 INT43944 Negative_regulation of Positive_regulation of Agt 4 0.42 1.44 1.93
73 INT15980 Positive_regulation of Positive_regulation of Agt 6 0.50 2.99 1.76
74 INT3152 Transcription of Agt 7 0.72 5.09 1.68
75 INT201475 Negative_regulation of Positive_regulation of Ednrb 6 0.42 3.74 1.66
76 INT125844 Positive_regulation of Gene_expression of Arrb2 2 0.48 0.45 1.66
77 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
78 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42
79 INT114298 Positive_regulation of Gene_expression of Ednrb 4 0.36 0.79 1.42
80 INT108936 Positive_regulation of Positive_regulation of Arrb2 1 0.41 0.25 1.4
81 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39
82 INT60772 Negative_regulation of Ednrb 8 0.41 4.56 1.39
83 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
84 INT239215 Binding of Agt 9 0.38 6.75 1.35
85 INT11306 Regulation of Gene_expression of Agt 7 0.45 3.29 1.31
86 INT133958 Localization of Bdkrb2 2 0.79 0.65 1.29
87 INT120406 Positive_regulation of Positive_regulation of BDKRB2 2 0.27 1.48 1.28
88 INT11241 Transcription of AGT 4 0.52 1.83 1.27
89 INT170031 Positive_regulation of Positive_regulation of Bdkrb2 1 0.09 0.94 1.27
90 INT19319 Negative_regulation of Binding of Agt 9 0.42 3.42 1.24
91 INT79916 Negative_regulation of Agt 14 0.47 6 1.22
92 INT47644 Positive_regulation of Localization of AGT 4 0.45 1.24 1.2
93 INT302068 Phosphorylation of Arrb2 1 0.01 0.27 1.19
94 INT28594 Positive_regulation of Transcription of Agt 2 0.47 1.3 1.15
95 INT115621 Positive_regulation of Binding of AGT 1 0.02 0 1.15
96 INT254634 Positive_regulation of Positive_regulation of Bdkrb2 2 0.32 1.64 1.13
97 INT67974 Positive_regulation of Gene_expression of Bdkrb2 3 0.37 1.13 1.12
98 INT242390 Regulation of Gene_expression of Bdkrb2 3 0.31 1.37 1.06
99 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
100 INT37802 Regulation of Positive_regulation of Bdkrb2 1 0.23 0.17 1.01
101 INT111048 Binding of Bdkrb2 2 0.47 2.54 1
102 INT108943 Positive_regulation of Negative_regulation of Arrb2 1 0.61 0.06 0.97
103 INT58291 Protein_catabolism of Bdkrb2 3 0.08 1.19 0.94
104 INT58292 Negative_regulation of Protein_catabolism of Bdkrb2 1 0.04 0.82 0.94
105 INT169336 Binding of Jak2 2 0.42 1.31 0.93
106 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
107 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
108 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
109 INT230806 Positive_regulation of Gene_expression of Agt 11 0.55 16.08 0.83
110 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
111 INT290271 Negative_regulation of Binding of BDKRB2 1 0.37 0.99 0.76
112 INT21943 Positive_regulation of Positive_regulation of AGT 6 0.46 3.29 0.75
113 INT34715 Regulation of Regulation of AGT 2 0.37 0.96 0.75
114 INT254632 Transcription of Bdkrb2 1 0.36 0.54 0.75
115 INT271462 Protein_catabolism of Bdkrb2 1 0.58 0.71 0.72
116 INT148074 Regulation of Agt 9 0.49 5.42 0.7
117 INT38735 Protein_catabolism of Agt 7 0.99 2.79 0.7
118 INT160461 Phosphorylation of Agt 1 0.31 0.4 0.7
119 INT160463 Positive_regulation of Phosphorylation of Agt 1 0.19 0.41 0.7
120 INT143814 Regulation of Localization of Bdkrb2 1 0.16 0.38 0.69
121 INT148911 Positive_regulation of Positive_regulation of GNA13 1 0.08 0.28 0.68
122 INT148912 Positive_regulation of GNA13 1 0.12 0.28 0.68
123 INT34769 Regulation of Gene_expression of AGT 3 0.19 1.39 0.67
124 INT133957 Positive_regulation of Localization of Bdkrb2 1 0.46 0.28 0.63
125 INT114299 Transcription of Ednrb 2 0.19 0.32 0.59
126 INT147679 Binding of Arrb2 1 0.24 0.22 0.58
127 INT49236 Localization of Bdkrb2 4 0.52 1.6 0.56
128 INT143813 Regulation of Negative_regulation of Bdkrb2 1 0.16 0.14 0.55
129 INT40021 Regulation of Binding of Agt 4 0.59 1.53 0.53
130 INT32618 Regulation of Positive_regulation of Agt 2 0.43 0.42 0.52
131 INT47645 Negative_regulation of Localization of AGT 2 0.11 1.09 0.49
132 INT184062 Binding of Jak2 5 0.37 3.13 0.47
133 INT99588 Positive_regulation of Binding of Agt 2 0.69 0.23 0.45
134 INT14039 Regulation of Regulation of Agt 1 0.30 0 0.44
135 INT201478 Regulation of Positive_regulation of Ednrb 1 0.35 0.68 0.44
136 INT205890 Transcription of Jak2 1 0.41 0.22 0.43
137 INT33017 Negative_regulation of Protein_catabolism of AGT 3 0.37 0 0.42
138 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41
139 INT168112 Phosphorylation of Arrb2 1 0.00 0 0.41
140 INT107462 Localization of Jak2 2 0.60 0.78 0.4
141 INT131106 Positive_regulation of Positive_regulation of Ednrb 1 0.15 0.91 0.4
142 INT271458 Regulation of Regulation of Bdkrb2 1 0.40 0.36 0.39
143 INT229697 Negative_regulation of Phosphorylation of Jak2 1 0.15 0.54 0.39
144 INT150812 Regulation of Regulation of Arrb2 1 0.26 0 0.38
145 INT201476 Positive_regulation of Negative_regulation of Ednrb 1 0.49 0.62 0.36
146 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35
147 INT205910 Negative_regulation of Positive_regulation of Jak2 1 0.33 0.26 0.35
148 INT95605 Regulation of Binding of AGT 3 0.44 0.2 0.34
149 INT27928 Phosphorylation of AGT 1 0.52 0.15 0.34
150 INT27929 Negative_regulation of Phosphorylation of AGT 1 0.27 0.15 0.34
151 INT4636 Positive_regulation of Regulation of Agt 4 0.50 1.3 0.3
152 INT43398 Regulation of Localization of Agt 1 0.28 0 0.3
153 INT3331 Positive_regulation of Protein_catabolism of AGT 1 0.33 0 0.27
154 INT164617 Protein_catabolism of Agt 2 0.79 5.3 0.25
155 INT239213 Localization of Agt 6 0.64 3.26 0.22
156 INT316230 Negative_regulation of Localization of BDKRB2 1 0.21 0.92 0.21
157 INT230802 Positive_regulation of Positive_regulation of Agt 2 0.40 0.41 0.2
158 INT55013 Localization of Ednrb 2 0.16 0.98 0.18
159 INT1770 Positive_regulation of Negative_regulation of Agt 2 0.49 1.09 0.17
160 INT256015 Negative_regulation of Regulation of Agt 1 0.18 0.16 0.17
161 INT328811 Negative_regulation of Localization of Jak2 1 0.34 0.13 0.17
162 INT79914 Positive_regulation of Negative_regulation of Agt 1 0.50 0.19 0.17
163 INT200802 Regulation of Jak2 5 0.61 2.86 0.16
164 INT8094 Positive_regulation of Gene_expression of BDKRB2 1 0.12 1.02 0.15
165 INT242342 Regulation of Ednrb 1 0.09 2.03 0.15
166 INT256004 Negative_regulation of Gene_expression of Agt 2 0.34 8.07 0.13
167 INT239214 Positive_regulation of Localization of Agt 2 0.55 1.89 0.13
168 INT119156 Positive_regulation of Protein_catabolism of Agt 1 0.49 0 0.13
169 INT214619 Positive_regulation of Negative_regulation of AGT 1 0.04 0.98 0.13
170 INT256008 Regulation of Gene_expression of Agt 4 0.36 5.03 0.11
171 INT278143 Positive_regulation of Negative_regulation of Jak2 1 0.16 0.54 0.11
172 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09
173 INT316232 Positive_regulation of Transcription of BDKRB2 1 0.23 0.7 0.09
174 INT316235 Transcription of BDKRB2 1 0.26 0.7 0.09
175 INT50849 Negative_regulation of Regulation of AGT 2 0.42 1.26 0.08
176 INT88135 Negative_regulation of Transcription of Agt 1 0.34 0.16 0.08
177 INT184018 Negative_regulation of Protein_catabolism of Jak2 1 0.36 1.76 0.08
178 INT173351 Binding of GNA13 1 0.08 0.05 0.08
179 INT184023 Protein_catabolism of Jak2 1 0.61 1.75 0.08
180 INT288915 Regulation of Positive_regulation of AGT 1 0.41 0.82 0.08
181 INT324892 Binding of Ednrb 1 0.06 0.32 0.06
182 INT354748 Negative_regulation of Protein_catabolism of Agt 1 0.43 0.58 0.04
183 INT230800 Positive_regulation of Regulation of Agt 1 0.40 1.1 0.04
184 INT264273 Localization of Ednrb 1 0.01 0 0.03
185 INT351640 Positive_regulation of Protein_catabolism of Agt 1 0.40 0.85 0.03
186 INT333025 Negative_regulation of Positive_regulation of Agt 3 0.34 0.74 0
187 INT27724 Regulation of Negative_regulation of Agt 2 0.35 0.32 0
188 INT241004 Transcription of Agt 2 0.42 7.14 0
189 INT333008 Regulation of Localization of Agt 1 0.10 0 0
190 INT161736 Negative_regulation of Gene_expression of Arrb2 1 0.50 0 0
191 INT307800 Negative_regulation of Transcription of Agt 1 0.25 4.61 0
192 INT202420 Transcription of Jak2 1 0.56 0.91 0
193 INT230797 Regulation of Negative_regulation of Agt 1 0.36 0.68 0
194 INT351641 Negative_regulation of Protein_catabolism of Agt 1 0.34 0.8 0
195 INT333023 Negative_regulation of Localization of Agt 1 0.09 0 0
196 INT351642 Negative_regulation of Binding of Agt 1 0.34 0.88 0
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