GO:0031748

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Name D1 dopamine receptor binding
Categary Function
Go Slim No
Go Link GO:0031748
Unique Molecular Interactions 30
Total Molecular Interactions 35
Total Single Events 241
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for D1 dopamine receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for D1 dopamine receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
2 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
3 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
4 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
5 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
6 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
7 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
8 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
9 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
10 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
11 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
12 INT139745 Positive_regulation of Binding of Oprm1 and Arrb2 1 0.28 0.14 0.81
13 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
14 INT104110 Negative_regulation of Adrbk2 Negative_regulation of Oprm1 1 0.00 0 0.71
15 INT104102 Negative_regulation of Adrbk2 Negative_regulation of Oprl1 1 0.06 0 0.7
16 INT96282 Cav2 Regulation of Positive_regulation of Gabrg1 1 0.25 0 0.48
17 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
18 INT143914 Binding of Rbm39 and Arrb2 1 0.03 0.07 0.37
19 INT83568 Adrbk2 Regulation of Oprk1 1 0.02 0 0.29
20 INT131963 Binding of CAV2 and ATXN2 1 0.04 1.39 0.21
21 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
22 INT121806 PHF21A Regulation of CAV2 1 0.00 0.24 0.2
23 INT343644 Grm5 Positive_regulation of Cav2 1 0.05 0 0.19
24 INT224125 Adrbk2 Positive_regulation of Phosphorylation of Adora3 1 0.04 0 0.13
25 INT72848 RT1-EC2 Positive_regulation of Adrbk2 1 0.00 0.33 0.1
26 INT72847 Adrbk2 Positive_regulation of Adrbk1 1 0.02 0.33 0.1
27 INT214980 Binding of Cav2 and Sigmar1 1 0.02 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for D1 dopamine receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in D1 dopamine receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
2 INT100079 Positive_regulation of Gene_expression of Arrb2 7 0.63 2.26 6.77
3 INT94979 Regulation of Arrb2 6 0.54 0.51 6.45
4 INT94986 Positive_regulation of Arrb2 5 0.61 1.3 6.24
5 INT54713 Gene_expression of Adrbk2 12 0.65 0.08 5.92
6 INT85685 Gene_expression of Arrb2 5 0.74 0.66 5.13
7 INT85681 Negative_regulation of Arrb2 5 0.47 0.79 4.71
8 INT108935 Transcription of Arrb2 5 0.59 0.5 4.38
9 INT92797 Regulation of Arrb2 4 0.44 0.81 4.28
10 INT94985 Regulation of Gene_expression of Arrb2 2 0.40 0.43 4.2
11 INT85679 Binding of Arrb2 4 0.39 0.79 3.82
12 INT94983 Negative_regulation of Arrb2 2 0.52 0.26 3.47
13 INT85682 Positive_regulation of Arrb2 4 0.46 0.22 3.05
14 INT292058 Positive_regulation of Cav2 7 0.67 3.43 2.89
15 INT149314 Negative_regulation of CAV2 5 0.42 1.21 2.76
16 INT282270 Gene_expression of Cav2 11 0.57 3.53 2.72
17 INT108937 Negative_regulation of Transcription of Arrb2 1 0.38 0.31 2.31
18 INT151878 Gene_expression of CAV2 18 0.66 9.26 2.17
19 INT108939 Regulation of Transcription of Arrb2 1 0.24 0.19 2.1
20 INT287525 Localization of CAV2 5 0.47 5.32 2
21 INT292051 Negative_regulation of Cav2 6 0.41 2.52 1.9
22 INT125844 Positive_regulation of Gene_expression of Arrb2 2 0.48 0.45 1.66
23 INT83563 Positive_regulation of Gene_expression of Adrbk2 2 0.58 0 1.57
24 INT54711 Regulation of Adrbk2 1 0.59 0 1.57
25 INT104106 Localization of Adrbk2 3 0.19 0.35 1.53
26 INT108936 Positive_regulation of Positive_regulation of Arrb2 1 0.41 0.25 1.4
27 INT54712 Positive_regulation of Adrbk2 3 0.66 0.34 1.35
28 INT302068 Phosphorylation of Arrb2 1 0.01 0.27 1.19
29 INT83566 Negative_regulation of Adrbk2 2 0.23 0 1.03
30 INT108943 Positive_regulation of Negative_regulation of Arrb2 1 0.61 0.06 0.97
31 INT292059 Positive_regulation of Gene_expression of Cav2 3 0.42 0.88 0.92
32 INT152326 Regulation of Gene_expression of CAV2 2 0.36 0.44 0.74
33 INT151877 Positive_regulation of Gene_expression of CAV2 2 0.40 0.39 0.72
34 INT104103 Positive_regulation of Localization of Adrbk2 1 0.08 0 0.69
35 INT147679 Binding of Arrb2 1 0.24 0.22 0.58
36 INT121810 Positive_regulation of CAV2 2 0.28 0.55 0.57
37 INT315028 Regulation of Cav2 2 0.43 0.86 0.54
38 INT298539 Binding of CAV2 2 0.39 0.95 0.48
39 INT168112 Phosphorylation of Arrb2 1 0.00 0 0.41
40 INT343628 Regulation of Positive_regulation of Cav2 1 0.19 0 0.4
41 INT150812 Regulation of Regulation of Arrb2 1 0.26 0 0.38
42 INT83561 Negative_regulation of Negative_regulation of Adrbk2 1 0.23 0 0.34
43 INT292064 Positive_regulation of Positive_regulation of Cav2 1 0.49 0.5 0.28
44 INT121809 Regulation of Positive_regulation of CAV2 1 0.25 0.26 0.2
45 INT329386 Positive_regulation of Localization of CAV2 1 0.17 0.19 0.16
46 INT224123 Transcription of Adrbk2 1 0.24 0 0.15
47 INT72844 Phosphorylation of Adrbk2 1 0.16 0.33 0.12
48 INT214973 Binding of Cav2 2 0.03 0.57 0.08
49 INT214968 Localization of Cav2 1 0.05 0.08 0.05
50 INT161736 Negative_regulation of Gene_expression of Arrb2 1 0.50 0 0
51 INT282279 Regulation of Gene_expression of Cav2 1 0.05 0.39 0
52 INT332316 Negative_regulation of Positive_regulation of Cav2 1 0.22 0 0
53 INT332317 Negative_regulation of Gene_expression of Cav2 1 0.25 0 0
54 INT332315 Positive_regulation of Negative_regulation of Cav2 1 0.26 0 0
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