GO:0031772

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Name type 2 hypocretin receptor binding
Categary Function
Go Slim No
Go Link GO:0031772
Unique Molecular Interactions 24
Total Molecular Interactions 33
Total Single Events 298
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for type 2 hypocretin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for type 2 hypocretin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130607 Hcrt Positive_regulation of H1 1 0.59 0.39 1.02
2 INT207439 Binding of HCRT and ERAL1 1 0.00 3.06 0.87
3 INT122102 Npy Negative_regulation of Hcrt 1 0.19 0.1 0.47
4 INT93464 Hcrt Negative_regulation of Pomc 1 0.18 0 0.31
5 INT88904 Binding of SCT and Hcrt 1 0.07 0 0.31
6 INT88903 Regulation of Binding of SCT and Hcrt 1 0.06 0 0.31
7 INT93465 Hcrt Negative_regulation of Localization of Gnrh1 1 0.36 0 0.31
8 INT275802 Hcrt Regulation of Rem1 1 0.20 0.95 0.17
9 INT275797 Binding of Hcrt and Pag1 1 0.20 0.14 0.16
10 INT258147 IGFBP3 Negative_regulation of Hcrt 1 0.28 1.87 0.11
11 INT275803 Hcrt Negative_regulation of Rem1 1 0.19 0.35 0.1
12 INT258143 Binding of Hcrt and Atxn3 1 0.15 1.93 0.08
13 INT291467 Binding of Hcrt and Hcrtr1 1 0.53 0.87 0.07
14 INT275799 Binding of Hcrt and Lynx1 1 0.01 0.34 0.07
15 INT258141 Binding of Hcrt and Gopc 1 0.06 0.93 0.06
16 INT275801 Binding of Hcrt and Sh2d1a 1 0.03 0.29 0.06
17 INT258140 Negative_regulation of Binding of Hcrt and Gopc 1 0.07 0.94 0.06
18 INT258148 Gene_expression of IGFBP3 Negative_regulation of Hcrt 1 0.28 0.86 0.04
19 INT258144 IGFBP3 Regulation of Gene_expression of Hcrt 1 0.30 2.23 0.03
20 INT258146 Binding of IGFBP3 and Hcrt 1 0.23 2.04 0
21 INT258145 IGFBP3 Regulation of Hcrt 1 0.16 0.56 0
22 INT258152 IGFBP3 Regulation of Transcription of Hcrt 1 0.40 0.42 0
23 INT258151 IGFBP3 Negative_regulation of Binding of Hcrt 1 0.28 0.49 0
24 INT258149 IGFBP3 Negative_regulation of Gene_expression of Hcrt 1 0.38 1.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for type 2 hypocretin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in type 2 hypocretin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106056 Gene_expression of Hcrt 77 0.76 35.35 8.16
2 INT81153 Gene_expression of Hcrt 31 0.77 6.04 8.16
3 INT84779 Positive_regulation of Hcrt 9 0.70 1.27 6.21
4 INT93463 Localization of Hcrt 13 0.78 1.58 3.51
5 INT106057 Negative_regulation of Hcrt 27 0.57 15.5 3.47
6 INT88748 Binding of Hcrt 7 0.47 0 3.22
7 INT113638 Negative_regulation of Hcrt 5 0.57 0.9 2.63
8 INT110139 Positive_regulation of Hcrt 7 0.67 2.14 2.26
9 INT81154 Gene_expression of HCRT 10 0.75 5.32 2.22
10 INT106055 Negative_regulation of Gene_expression of Hcrt 15 0.46 5.64 2.09
11 INT81152 Regulation of Hcrt 6 0.45 1.27 2.08
12 INT117585 Regulation of Hcrt 10 0.56 6.16 1.77
13 INT140621 Localization of Hcrt 7 0.73 2.6 1.64
14 INT151954 Positive_regulation of HCRT 2 0.67 1.79 1.56
15 INT151955 Regulation of HCRT 1 0.12 1.2 1.39
16 INT128019 Transcription of Hcrt 3 0.41 0.12 1.34
17 INT113635 Positive_regulation of Localization of Hcrt 1 0.49 0.51 1.06
18 INT132833 Positive_regulation of Gene_expression of Hcrt 4 0.55 3.1 1.01
19 INT127709 Positive_regulation of Gene_expression of Hcrt 3 0.45 0.55 0.84
20 INT99281 Negative_regulation of HCRT 3 0.57 2.26 0.71
21 INT213651 Binding of HCRT 2 0.36 1.08 0.56
22 INT109643 Localization of HCRT 2 0.78 0 0.55
23 INT82266 Transcription of Hcrt 4 0.68 2.77 0.46
24 INT129285 Negative_regulation of Localization of Hcrt 1 0.57 0 0.45
25 INT127710 Negative_regulation of Gene_expression of Hcrt 2 0.39 0.34 0.37
26 INT88897 Regulation of Binding of Hcrt 1 0.60 0 0.37
27 INT258092 Regulation of Gene_expression of Hcrt 2 0.44 2.6 0.29
28 INT258096 Binding of Hcrt 5 0.36 3.2 0.18
29 INT266755 Positive_regulation of Positive_regulation of HCRT 1 0.49 0 0.07
30 INT88898 Positive_regulation of Binding of Hcrt 1 0.49 0 0.07
31 INT260015 Regulation of Positive_regulation of Hcrt 1 0.26 0 0.03
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