GO:0031781

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Name type 3 melanocortin receptor binding
Categary Function
Go Slim No
Go Link GO:0031781
Unique Molecular Interactions 864
Total Molecular Interactions 1464
Total Single Events 13886
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for type 3 melanocortin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for type 3 melanocortin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69872 Binding of MC1R and POMC 52 0.54 8.87 18.3
2 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49
3 INT10268 Binding of PDYN and POMC 11 0.39 0.08 10.36
4 INT6079 Pomc Positive_regulation of Penk 9 0.43 0 9.46
5 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18
6 INT91538 Pomc Positive_regulation of P9Ehs1 6 0.11 1.47 6.23
7 INT92466 Pomc Positive_regulation of Binding of Crygs 8 0.06 0 5.56
8 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
9 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96
10 INT211710 Binding of Mc1r and a 7 0.44 0.37 4.78
11 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
12 INT32444 Binding of Cpe and Pomc 2 0.22 0 4.47
13 INT113223 POMC Regulation of MC1R 6 0.68 0.39 4.24
14 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19
15 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06
16 INT34220 Binding of POMC and Oprl1 4 0.01 0.25 4.05
17 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93
18 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4
19 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35
20 INT7436 CFP Positive_regulation of Binding of POMC 1 0.02 0.18 3.35
21 INT17456 Binding of CSF2 and POMC 3 0.32 4.06 3.15
22 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 0.31 0 3.14
23 INT81708 POMC Regulation of Gene_expression of ITGAM 1 0.53 0.72 3.1
24 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9
25 INT32656 Pomc Positive_regulation of Rbm39 1 0.08 0.42 2.84
26 INT107723 POMC Positive_regulation of MC1R 7 0.68 0.71 2.82
27 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
28 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61
29 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
30 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
31 INT56726 Cpe Negative_regulation of Pomc 1 0.07 0 2.41
32 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39
33 INT51317 Binding of POMC and OR5D2P 1 0.00 0.6 2.23
34 INT34310 CRH Positive_regulation of POMC 3 0.42 0.62 2.21
35 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19
36 INT1315 Pomc Positive_regulation of Localization of Gnrhr 3 0.38 0.16 2.16
37 INT49242 Binding of Mc1r and Pomc 10 0.38 3.79 2.15
38 INT28387 Pomc Positive_regulation of Localization of LH 2 0.40 0.28 2.07
39 INT138962 Dbi Positive_regulation of Pomc 1 0.00 1.53 2
40 INT32585 H2-Ab1 Negative_regulation of Pomc 1 0.03 0.13 2
41 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
42 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
43 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
44 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
45 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
46 INT31438 Penk Positive_regulation of Localization of Pomc 1 0.18 0 1.9
47 INT19496 Pomc Regulation of Localization of Ins1 1 0.55 0.33 1.82
48 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73
49 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
50 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
51 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
52 INT32412 Penk Regulation of Pomc 3 0.21 0.36 1.62
53 INT86637 POMC Regulation of Gene_expression of KRT16 2 0.47 1.22 1.61
54 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
55 INT66408 Pomc Positive_regulation of Regulation of HRH1 1 0.01 0 1.58
56 INT41652 Binding of Pomc and Oprl1 3 0.16 0 1.57
57 INT94271 Pomc Regulation of Avp 1 0.20 0.67 1.57
58 INT81710 POMC Regulation of Gene_expression of FCGR3B 1 0.50 0.34 1.57
59 INT81709 POMC Regulation of Gene_expression of ITGB2 1 0.40 0.34 1.57
60 INT81719 POMC Regulation of Gene_expression of ITGAL 1 0.35 0.34 1.57
61 INT81712 POMC Regulation of FCGR3B 1 0.16 0.34 1.56
62 INT81715 POMC Regulation of ITGB2 1 0.40 0.34 1.55
63 INT81721 POMC Regulation of ITGAM 1 0.39 0.34 1.55
64 INT81714 POMC Regulation of ITGAL 1 0.15 0.34 1.54
65 INT32152 POMC Positive_regulation of Gene_expression of IFNA1 2 0.67 0 1.53
66 INT145072 ASIP Negative_regulation of MC1R 1 0.29 0 1.52
67 INT23548 Negative_regulation of CNDP2 Negative_regulation of Localization of POMC 1 0.03 0 1.52
68 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52
69 INT69709 NPL Positive_regulation of Localization of POMC 2 0.36 1.22 1.51
70 INT32657 Positive_regulation of Pomc Positive_regulation of Rbm39 1 0.08 0.22 1.51
71 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
72 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51
73 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
74 INT40209 TNS3 Regulation of POMC 1 0.16 0.27 1.47
75 INT12691 SST Negative_regulation of Localization of POMC 3 0.24 1.24 1.45
76 INT1314 Pomc Regulation of Localization of Gnrhr 2 0.16 0.14 1.45
77 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
78 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
79 INT154111 POMC Positive_regulation of Localization of PENK 1 0.34 0.05 1.41
80 INT28992 Tmpo Positive_regulation of Pomc 1 0.36 3.18 1.41
81 INT154110 PENK Positive_regulation of Localization of POMC 1 0.34 0.05 1.41
82 INT154113 POMC Positive_regulation of YY1 1 0.70 0.06 1.41
83 INT27123 Binding of Pomc and Cck 2 0.31 0 1.38
84 INT66569 Pomc Positive_regulation of Atxn2l 1 0.03 0 1.36
85 INT38453 Binding of Pomc and Penk 1 0.17 0 1.33
86 INT2641 Binding of Pomc and Lct 2 0.31 0.57 1.32
87 INT59446 Rbm39 Positive_regulation of Negative_regulation of Pomc 1 0.03 0.19 1.32
88 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
89 INT86636 POMC Positive_regulation of Gene_expression of KRT16 2 0.39 0.83 1.28
90 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
91 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
92 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
93 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
94 INT46853 POMC Regulation of GAST 1 0.11 0.07 1.26
95 INT45269 POMC Negative_regulation of Penk 1 0.01 0 1.24
96 INT34471 Negative_regulation of Pomc Regulation of Slc3a1 1 0.05 0.12 1.24
97 INT123453 Binding of POMC and Penk 1 0.01 0.31 1.23
98 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
99 INT34473 Pomc Regulation of Slc3a1 1 0.03 0.07 1.23
100 INT40900 PDYN Regulation of Localization of POMC 2 0.07 0.56 1.22
101 INT82754 Cck Positive_regulation of Positive_regulation of Pomc 1 0.39 0.3 1.21
102 INT17601 Binding of POMC and Oprl1 1 0.01 0 1.2
103 INT35459 POMC Negative_regulation of Gene_expression of IL16 1 0.45 0 1.19
104 INT34661 Abat Positive_regulation of Localization of Pomc 1 0.04 0 1.18
105 INT43509 Avp Positive_regulation of Localization of POMC 2 0.13 1.26 1.16
106 INT105240 POMC Positive_regulation of Gene_expression of CXCL10 1 0.07 1.18 1.16
107 INT88778 Binding of Oprm1 and Pomc 3 0.21 0.56 1.14
108 INT13098 POMC Regulation of Localization of CGA 1 0.58 0 1.14
109 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13
110 INT59035 Binding of CPB1 and POMC 1 0.00 0 1.12
111 INT102421 POMC Regulation of Gene_expression of Fos 1 0.12 0.34 1.11
112 INT29874 OXTR Negative_regulation of POMC 1 0.22 0 1.1
113 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 0.42 1.09 1.07
114 INT69874 POMC Negative_regulation of TYRP1 1 0.13 0 1.07
115 INT69871 ASIP Negative_regulation of TYRP1 1 0.36 0 1.07
116 INT30575 SST Negative_regulation of Localization of Pomc 1 0.00 0.71 1.06
117 INT57508 Pomc Negative_regulation of Adarb1 1 0.01 0.22 1.05
118 INT58807 Pomc Negative_regulation of Localization of LH 2 0.06 0 1.02
119 INT19494 Pomc Positive_regulation of Localization of Ins1 2 0.62 0.38 1.02
120 INT101381 POMC Regulation of Localization of IL8 1 0.28 1.49 1.02
121 INT160879 POMC Positive_regulation of DECR1 1 0.04 0.08 1.02
122 INT106706 POMC Negative_regulation of Binding of FN1 1 0.19 0.79 1.02
123 INT6930 Binding of Oprk1 and Pomc 1 0.08 0.16 1.01
124 INT21415 POMC Positive_regulation of Gene_expression of IL2 1 0.00 0.27 1
125 INT32327 POMC Positive_regulation of Localization of PRL 4 0.45 0 0.99
126 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99
127 INT22109 Positive_regulation of Pomc Positive_regulation of Penk 1 0.35 0 0.99
128 INT38579 Binding of POMC and Hps4 1 0.00 0.32 0.99
129 INT1415 Binding of OPRM1 and POMC 3 0.16 0.3 0.98
130 INT31494 Pomc Regulation of Crh 2 0.12 0.13 0.97
131 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
132 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
133 INT43454 Pomc Regulation of Localization of Avp 2 0.24 0.89 0.94
134 INT106707 POMC Regulation of Binding of LAMB2 1 0.03 0.7 0.94
135 INT1654 Pomc Regulation of DSP 1 0.03 0 0.94
136 INT20888 POMC Positive_regulation of Localization of PDYN 1 0.40 0 0.92
137 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
138 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
139 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
140 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
141 INT86589 Oprd1 Regulation of Localization of Pomc 1 0.18 0 0.9
142 INT56779 Pomc Negative_regulation of Gene_expression of Odc1 2 0.31 0 0.89
143 INT161916 Binding of POMC and Oprd1 1 0.01 0 0.89
144 INT161917 Negative_regulation of Binding of POMC and Oprd1 1 0.01 0 0.89
145 INT264944 Binding of POMC and BOC 1 0.07 0.44 0.89
146 INT26991 Pomc Negative_regulation of Localization of Ins1 1 0.38 0 0.89
147 INT97184 Oprm1 Regulation of Gene_expression of Pomc 1 0.31 0 0.89
148 INT66371 Pomc Regulation of Gene_expression of Crh 2 0.49 0 0.88
149 INT161915 Negative_regulation of Binding of POMC and YY1 1 0.33 0 0.88
150 INT26987 Pomc Regulation of Ins1 1 0.40 0 0.87
151 INT31495 Pomc Regulation of Localization of Gnrh1 2 0.04 0 0.86
152 INT40742 Pomc Regulation of Localization of Gh1 1 0.37 0 0.86
153 INT59497 Adh1 Regulation of POMC 1 0.03 0 0.86
154 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
155 INT5451 CRH Regulation of POMC 2 0.28 0.39 0.85
156 INT161306 POMC Negative_regulation of Transcription of IL2 1 0.24 0.27 0.85
157 INT100283 TXN Negative_regulation of Gene_expression of POMC 1 0.54 0.5 0.85
158 INT32441 POMC Positive_regulation of ELANE 1 0.13 0.09 0.83
159 INT1582 Binding of PENK and POMC 1 0.16 0 0.83
160 INT79617 Htr1a Positive_regulation of Localization of POMC 1 0.38 0 0.83
161 INT120149 Positive_regulation of Pomc Positive_regulation of Localization of Ins1 1 0.03 0.09 0.82
162 INT128943 Pomc Regulation of Npy 1 0.23 0.61 0.81
163 INT12883 Binding of IL2 and POMC 1 0.01 0 0.81
164 INT107937 POMC Regulation of Gene_expression of TGFBR2 1 0.28 0.82 0.81
165 INT150681 Pomc Positive_regulation of Camk2a 1 0.47 0.07 0.8
166 INT40743 Binding of Gh1 and Pomc 1 0.22 0 0.8
167 INT150680 Pomc Negative_regulation of Gene_expression of Eif2ak3 1 0.35 0.07 0.8
168 INT150679 Pomc Regulation of Gene_expression of Camk2a 1 0.30 0.07 0.79
169 INT9527 Avp Positive_regulation of Localization of Pomc 7 0.58 0.29 0.77
170 INT18099 POMC Positive_regulation of Binding of Prl 1 0.00 0 0.76
171 INT42929 Pomc Negative_regulation of Localization of Oxt 1 0.11 0 0.76
172 INT29913 Binding of FANCB and Pomc 1 0.01 0 0.76
173 INT113222 POMC Regulation of Gene_expression of MC1R 1 0.06 0 0.76
174 INT32163 Binding of CALM1 and POMC 4 0.46 0 0.75
175 INT164055 POMC Regulation of Agrp 1 0.29 0.3 0.75
176 INT164057 POMC Regulation of Pomc 1 0.09 0.3 0.75
177 INT26982 Cpe Regulation of Localization of Pomc 1 0.01 0 0.75
178 INT41455 Binding of Pomc and Pdyn 1 0.04 0 0.75
179 INT113224 Binding of ASIP and MC1R 1 0.00 0 0.75
180 INT124404 Binding of POMC and Oprm1 1 0.00 0.25 0.75
181 INT164056 Agrp Regulation of POMC 1 0.29 0.3 0.75
182 INT131468 Positive_regulation of POMC Positive_regulation of MC1R 1 0.00 0 0.74
183 INT40826 Pomc Negative_regulation of Binding of Sstr1 1 0.05 0 0.74
184 INT113225 POMC Regulation of Transcription of MC1R 1 0.03 0 0.74
185 INT288371 Binding of Atrn and a 1 0.39 0 0.74
186 INT31642 POMC Regulation of GCG 1 0.41 0.62 0.73
187 INT164052 Agrp Regulation of Pomc 1 0.16 0.29 0.73
188 INT26986 Cpe Regulation of Pomc 1 0.01 0 0.73
189 INT31643 POMC Regulation of INS 1 0.59 0.62 0.73
190 INT45305 Pomc Positive_regulation of Localization of Avp 1 0.12 0 0.73
191 INT26990 Pomc Regulation of Cpe 1 0.01 0 0.73
192 INT9290 Pomc Regulation of Prl 2 0.09 0.69 0.71
193 INT26872 ABAT Positive_regulation of Localization of POMC 1 0.03 0 0.71
194 INT29324 Trmt2a Negative_regulation of Binding of Pomc 1 0.00 0 0.71
195 INT81735 Binding of Ins1 and Pomc 1 0.20 2.24 0.71
196 INT110577 MME Positive_regulation of Protein_catabolism of POMC 1 0.49 0.06 0.71
197 INT1312 Pomc Positive_regulation of Gnrhr 2 0.11 0.22 0.7
198 INT82378 Sst Regulation of Localization of Pomc 1 0.23 0.6 0.7
199 INT29875 OXTR Negative_regulation of Positive_regulation of POMC 1 0.31 0 0.7
200 INT12711 POMC Regulation of Prl 1 0.04 1.25 0.7

Single Events

The table below shows the top 100 pain related interactions that have been reported for type 3 melanocortin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in type 3 melanocortin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT443 Localization of POMC 1020 0.81 284.52 443.17
2 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16
3 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83
4 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98
5 INT738 Regulation of POMC 459 0.62 111.19 243.74
6 INT1308 Localization of Pomc 457 0.81 66.83 217.5
7 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24
8 INT1652 Regulation of Pomc 387 0.62 61.01 186.51
9 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77
10 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63
11 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37
12 INT695 Binding of POMC 304 0.48 56.66 126.85
13 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64
14 INT1438 Localization of Pomc 360 0.81 101.26 116.47
15 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84
16 INT462 Regulation of Pomc 157 0.62 41.67 67.27
17 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97
18 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48
19 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34
20 INT1463 Binding of Pomc 129 0.48 15.89 56.27
21 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3
22 INT1197 Negative_regulation of Localization of POMC 109 0.59 28.29 48.02
23 INT1295 Binding of Pomc 85 0.48 12.92 42.8
24 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97
25 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67
26 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09
27 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01
28 INT5505 Regulation of Localization of Pomc 54 0.61 6.96 30.77
29 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58
30 INT6174 Regulation of Gene_expression of POMC 49 0.61 9.75 27.69
31 INT7565 Transcription of Pomc 69 0.72 14.46 27.41
32 INT2290 Protein_catabolism of POMC 41 0.99 4.86 23.36
33 INT9526 Negative_regulation of Localization of Pomc 41 0.58 6.93 23.3
34 INT55251 Gene_expression of a 142 0.67 81.21 23.03
35 INT5511 Negative_regulation of Gene_expression of Pomc 47 0.59 12.08 23.02
36 INT636 Binding of MRAP 54 0.48 40.36 18.77
37 INT11628 Regulation of Localization of Pomc 44 0.61 10.46 18.66
38 INT3118 Negative_regulation of Positive_regulation of POMC 33 0.59 9.42 18.07
39 INT1416 Transcription of POMC 40 0.72 10.71 15.38
40 INT15643 Positive_regulation of Positive_regulation of Pomc 30 0.65 4.59 15.34
41 INT6278 Negative_regulation of Gene_expression of Pomc 35 0.59 11.07 14.8
42 INT27266 Regulation of Gene_expression of Pomc 41 0.62 6.74 14.59
43 INT6947 Negative_regulation of Gene_expression of POMC 37 0.59 10.32 14.14
44 INT1873 Gene_expression of MRAP 51 0.76 31.75 13.92
45 INT5515 Negative_regulation of Positive_regulation of Pomc 25 0.58 8.73 11.88
46 INT1436 Negative_regulation of Localization of Pomc 41 0.58 10.85 11.26
47 INT637 Positive_regulation of MRAP 23 0.67 21.13 9.97
48 INT1591 Negative_regulation of Binding of POMC 18 0.59 1.74 7.91
49 INT93507 Gene_expression of ASIP 14 0.60 3.98 7.55
50 INT11839 Protein_catabolism of Pomc 15 0.98 0.77 6.99
51 INT26181 Positive_regulation of Negative_regulation of POMC 12 0.70 1.03 6.14
52 INT32532 Regulation of Positive_regulation of Pomc 11 0.61 3.2 5.93
53 INT27408 Phosphorylation of POMC 9 0.80 2.18 5.88
54 INT6276 Negative_regulation of Positive_regulation of Pomc 12 0.57 3.65 5.49
55 INT94652 Binding of a 15 0.48 4.18 5.4
56 INT21254 Regulation of Positive_regulation of POMC 12 0.61 3.64 4.67
57 INT14580 Regulation of Regulation of POMC 8 0.44 1.49 4.63
58 INT24820 Positive_regulation of Binding of POMC 9 0.67 2.98 4.6
59 INT7575 Regulation of Transcription of Pomc 8 0.60 1.57 4.59
60 INT10806 Positive_regulation of Transcription of Pomc 13 0.50 1.74 4.58
61 INT24420 Transcription of Pomc 13 0.69 3.32 4.54
62 INT30444 Negative_regulation of Protein_catabolism of POMC 4 0.51 2.11 4.53
63 INT22337 Negative_regulation of Transcription of Pomc 12 0.59 2.17 4.32
64 INT178261 Positive_regulation of Gene_expression of a 23 0.55 14.67 4.07
65 INT14499 Regulation of Regulation of Pomc 7 0.61 0.15 4.06
66 INT30074 Positive_regulation of Negative_regulation of Pomc 7 0.50 0.99 3.58
67 INT20408 Regulation of Negative_regulation of Pomc 3 0.45 0.38 3.51
68 INT34678 Regulation of Negative_regulation of Pomc 8 0.62 1.24 3.47
69 INT5508 Negative_regulation of Negative_regulation of Pomc 10 0.53 1.57 3.22
70 INT211708 Regulation of a 4 0.42 1.92 3.15
71 INT17883 Regulation of MRAP 8 0.44 3.59 3.12
72 INT25611 Negative_regulation of Binding of Pomc 6 0.56 1.05 2.74
73 INT1586 Regulation of Binding of POMC 7 0.45 1.14 2.61
74 INT33697 Regulation of Positive_regulation of Pomc 5 0.45 0.83 2.5
75 INT13748 Negative_regulation of Regulation of Pomc 4 0.41 0.63 2.5
76 INT25438 Positive_regulation of Positive_regulation of Pomc 6 0.48 4 2.37
77 INT178246 Negative_regulation of Gene_expression of a 8 0.43 4.27 2.19
78 INT178260 Positive_regulation of a 6 0.50 3.09 2.08
79 INT91608 Negative_regulation of ASIP 3 0.40 0.51 2.04
80 INT13294 Negative_regulation of Regulation of Pomc 5 0.38 2.83 2.01
81 INT42497 Regulation of Negative_regulation of POMC 4 0.44 0.63 1.99
82 INT25952 Negative_regulation of Regulation of POMC 4 0.36 0.76 1.96
83 INT88269 Binding of ASIP 4 0.19 0.41 1.82
84 INT41580 Negative_regulation of Negative_regulation of POMC 5 0.50 0.46 1.79
85 INT6246 Negative_regulation of Negative_regulation of Pomc 3 0.43 1.34 1.78
86 INT6722 Regulation of Binding of Pomc 4 0.45 0.17 1.75
87 INT6130 Positive_regulation of Regulation of POMC 6 0.69 3.57 1.7
88 INT2016 Negative_regulation of MRAP 6 0.41 3.21 1.59
89 INT33245 Negative_regulation of Binding of Pomc 6 0.52 0 1.52
90 INT32575 Negative_regulation of Protein_catabolism of Pomc 1 0.41 0.18 1.42
91 INT178249 Regulation of Gene_expression of a 4 0.35 2.3 1.39
92 INT32805 Regulation of Regulation of Pomc 2 0.42 0.1 1.35
93 INT23693 Positive_regulation of Protein_catabolism of Pomc 1 0.38 0 1.35
94 INT39580 Positive_regulation of Regulation of Pomc 3 0.49 0 1.33
95 INT40102 Positive_regulation of Phosphorylation of POMC 3 0.44 0.57 1.3
96 INT178255 Localization of a 4 0.65 0.72 1.1
97 INT33048 Positive_regulation of Protein_catabolism of POMC 1 0.04 0 1.02
98 INT178252 Transcription of a 3 0.67 0.73 0.9
99 INT162073 Negative_regulation of Transcription of POMC 1 0.34 0.34 0.88
100 INT131007 Positive_regulation of Transcription of Pomc 2 0.49 1.68 0.86
101 INT172055 Positive_regulation of Binding of MRAP 1 0.33 1.69 0.84
102 INT145073 Regulation of Gene_expression of ASIP 1 0.27 0 0.83
103 INT118986 Positive_regulation of Gene_expression of ASIP 1 0.39 0.97 0.8
104 INT18229 Positive_regulation of Regulation of Pomc 2 0.44 0.15 0.76
105 INT30280 Phosphorylation of Pomc 2 0.16 0.13 0.73
106 INT3690 Protein_catabolism of Pomc 6 0.96 0.6 0.6
107 INT46231 Regulation of Protein_catabolism of POMC 1 0.05 0 0.6
108 INT718 Localization of MRAP 1 0.68 1.03 0.59
109 INT23561 Positive_regulation of Negative_regulation of Pomc 1 0.47 0.25 0.57
110 INT163222 Protein_catabolism of a 2 1.00 1.17 0.56
111 INT211707 Positive_regulation of Transcription of a 2 0.51 0.27 0.55
112 INT178248 Negative_regulation of a 4 0.43 1 0.46
113 INT128792 Transcription of MRAP 1 0.38 0.39 0.39
114 INT21405 Regulation of Binding of Pomc 1 0.10 0 0.34
115 INT39579 Regulation of Transcription of Pomc 1 0.26 0 0.33
116 INT128288 Negative_regulation of Phosphorylation of POMC 1 0.37 0.17 0.33
117 INT281025 Positive_regulation of Phosphorylation of Pomc 1 0.10 0.14 0.3
118 INT132532 Positive_regulation of Gene_expression of MRAP 1 0.49 0.63 0.28
119 INT1115 Regulation of Positive_regulation of MRAP 1 0.45 0.44 0.25
120 INT54039 Positive_regulation of Transcription of POMC 2 0.67 3.24 0.23
121 INT40143 Positive_regulation of Binding of Pomc 1 0.50 0 0.17
122 INT120321 Regulation of Transcription of POMC 1 0.18 0.95 0.17
123 INT178256 Negative_regulation of Binding of a 1 0.33 0.94 0.15
124 INT294483 Negative_regulation of Transcription of Pomc 1 0.42 0.9 0.1
125 INT56836 Regulation of Binding of MRAP 1 0.02 0.2 0.1
126 INT276280 Regulation of Localization of a 1 0.37 0.33 0.09
127 INT3374 Positive_regulation of Positive_regulation of MRAP 1 0.49 0.7 0.07
128 INT11697 Positive_regulation of Negative_regulation of MRAP 1 0.49 0.08 0.04
129 INT178259 Positive_regulation of Binding of a 1 0.39 0.39 0
130 INT130598 Negative_regulation of Gene_expression of MRAP 1 0.35 0.19 0
131 INT178254 Regulation of Transcription of a 1 0.35 0.47 0
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