GO:0031826

From wiki-pain
Jump to: navigation, search
Name type 2A serotonin receptor binding
Categary Function
Go Slim No
Go Link GO:0031826
Unique Molecular Interactions 36
Total Molecular Interactions 45
Total Single Events 247
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for type 2A serotonin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for type 2A serotonin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
2 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
3 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
4 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
5 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
6 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
7 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
8 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
9 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
10 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
11 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
12 INT139745 Positive_regulation of Binding of Oprm1 and Arrb2 1 0.28 0.14 0.81
13 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
14 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
15 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
16 INT143914 Binding of Rbm39 and Arrb2 1 0.03 0.07 0.37
17 INT173356 Gnaq Positive_regulation of CDK20 1 0.06 0 0.37
18 INT173358 Gnaq Positive_regulation of SMPD1 1 0.01 0.13 0.23
19 INT173357 Gnaq Positive_regulation of PRKCA 1 0.01 0 0.22
20 INT72019 Binding of Gnaq and Ptprg 1 0.01 0 0.21
21 INT227593 Gnaq Negative_regulation of GLUL 1 0.01 0 0.06

Single Events

The table below shows the top 100 pain related interactions that have been reported for type 2A serotonin receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in type 2A serotonin receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
2 INT100079 Positive_regulation of Gene_expression of Arrb2 7 0.63 2.26 6.77
3 INT94979 Regulation of Arrb2 6 0.54 0.51 6.45
4 INT94986 Positive_regulation of Arrb2 5 0.61 1.3 6.24
5 INT72000 Gene_expression of Gnaq 17 0.75 3.12 5.48
6 INT85685 Gene_expression of Arrb2 5 0.74 0.66 5.13
7 INT85681 Negative_regulation of Arrb2 5 0.47 0.79 4.71
8 INT108935 Transcription of Arrb2 5 0.59 0.5 4.38
9 INT92797 Regulation of Arrb2 4 0.44 0.81 4.28
10 INT94985 Regulation of Gene_expression of Arrb2 2 0.40 0.43 4.2
11 INT85679 Binding of Arrb2 4 0.39 0.79 3.82
12 INT94983 Negative_regulation of Arrb2 2 0.52 0.26 3.47
13 INT85682 Positive_regulation of Arrb2 4 0.46 0.22 3.05
14 INT108937 Negative_regulation of Transcription of Arrb2 1 0.38 0.31 2.31
15 INT108939 Regulation of Transcription of Arrb2 1 0.24 0.19 2.1
16 INT112880 Positive_regulation of Gnaq 17 0.49 1.97 1.95
17 INT125844 Positive_regulation of Gene_expression of Arrb2 2 0.48 0.45 1.66
18 INT110189 Regulation of Gnaq 3 0.02 0.26 1.63
19 INT71999 Negative_regulation of Gene_expression of Gnaq 3 0.41 0.08 1.56
20 INT108936 Positive_regulation of Positive_regulation of Arrb2 1 0.41 0.25 1.4
21 INT110188 Regulation of Gene_expression of Gnaq 2 0.25 0.85 1.22
22 INT302068 Phosphorylation of Arrb2 1 0.01 0.27 1.19
23 INT72002 Negative_regulation of Gnaq 7 0.35 0.2 1.02
24 INT108943 Positive_regulation of Negative_regulation of Arrb2 1 0.61 0.06 0.97
25 INT110187 Regulation of Regulation of Gnaq 1 0.00 0.07 0.82
26 INT141915 Positive_regulation of Gene_expression of Gnaq 3 0.19 1.31 0.76
27 INT147679 Binding of Arrb2 1 0.24 0.22 0.58
28 INT112881 Positive_regulation of Positive_regulation of Gnaq 2 0.49 0.86 0.54
29 INT141919 Positive_regulation of Transcription of Gnaq 1 0.21 1.05 0.49
30 INT141912 Negative_regulation of Transcription of Gnaq 1 0.18 1.07 0.49
31 INT141917 Transcription of Gnaq 1 0.29 1.05 0.49
32 INT168112 Phosphorylation of Arrb2 1 0.00 0 0.41
33 INT150812 Regulation of Regulation of Arrb2 1 0.26 0 0.38
34 INT149315 Binding of Gnaq 2 0.04 0 0.26
35 INT272710 Phosphorylation of Gnaq 1 0.09 0.12 0.12
36 INT227570 Localization of Gnaq 1 0.07 0 0.04
37 INT227569 Negative_regulation of Positive_regulation of Gnaq 1 0.04 0.08 0.04
38 INT161736 Negative_regulation of Gene_expression of Arrb2 1 0.50 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox