GO:0031838

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Name haptoglobin-hemoglobin complex
Categary Component
Go Slim No
Go Link GO:0031838
Unique Molecular Interactions 37
Total Molecular Interactions 49
Total Single Events 820
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for haptoglobin-hemoglobin complex. They are ordered first by their pain relevance and then by number of times they were reported for haptoglobin-hemoglobin complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
2 INT143323 Binding of HLA-B and HP 1 0.04 0.95 0.93
3 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
4 INT82767 Binding of HP and MLRG 1 0.00 0 0.71
5 INT18231 Binding of ADRA1D and HP 2 0.14 0.17 0.64
6 INT26648 Binding of CEL and HP 1 0.04 0 0.58
7 INT117309 HP Positive_regulation of Gast 1 0.00 0.9 0.51
8 INT102214 ENG Negative_regulation of HP 1 0.01 0 0.49
9 INT102213 Binding of ENG and HP 1 0.01 0 0.47
10 INT117310 HP Regulation of Gbf1 1 0.00 0.86 0.46
11 INT159755 HP Regulation of OXA1L 1 0.01 0 0.44
12 INT29292 POMC Negative_regulation of HP 1 0.01 0 0.34
13 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
14 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
15 INT273130 Negative_regulation of Binding of Drd2 and Hp 1 0.05 0 0.28
16 INT273129 Binding of Drd2 and Hp 1 0.04 0 0.28
17 INT145542 HP Negative_regulation of Positive_regulation of TRPV1 1 0.00 0.07 0.27
18 INT206427 Binding of HP and SULT1A3 1 0.03 0 0.27
19 INT308551 Binding of HP and VPS45 1 0.04 0.44 0.15
20 INT295273 STAT1 Regulation of Transcription of Hp 1 0.00 0.63 0.15
21 INT31697 Binding of HP and PTGER1 1 0.01 0 0.15
22 INT295272 STAT1 Regulation of Hp 1 0.00 0.63 0.14
23 INT178351 Binding of Il6 and Hp 1 0.00 0.61 0.14
24 INT18230 Binding of HP and WWOX 1 0.19 0.17 0.13
25 INT344947 IPP Regulation of HP 1 0.03 0.81 0.12
26 INT344965 Phc1 Regulation of HP 1 0.02 0.95 0.09
27 INT304189 Binding of HP and ADHD1 1 0.02 2.59 0.07
28 INT285402 HP Positive_regulation of Gene_expression of ROS1 1 0.00 0.51 0.05
29 INT204079 HP Positive_regulation of Gene_expression of Cdkn1b 1 0.00 0.6 0.05
30 INT47870 Hpd Regulation of Hbb 1 0.20 0.06 0.03
31 INT304190 Binding of HP and ZFP91 1 0.00 2.74 0.03
32 INT344964 Phc1 Positive_regulation of HP 1 0.04 1.36 0
33 INT213176 Binding of HP and SHBG 1 0.02 1.07 0
34 INT204076 HP Positive_regulation of Gene_expression of Fas 1 0.00 1.81 0
35 INT213175 Binding of DBP and HP 1 0.03 1.08 0
36 INT318329 Binding of HBA1 and HBB 1 0.02 1 0
37 INT320054 Binding of C2 and Hbb 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for haptoglobin-hemoglobin complex. They are ordered first by their pain relevance and then by number of times they were reported in haptoglobin-hemoglobin complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89
2 INT8548 Gene_expression of HP 86 0.77 47.62 11.94
3 INT192967 Gene_expression of Hp 14 0.43 8.06 11.01
4 INT273123 Binding of Hp 1 0.25 3.56 10.9
5 INT4159 Gene_expression of Hp 33 0.72 12.49 8.39
6 INT3401 Positive_regulation of Hp 22 0.69 16.33 7.97
7 INT14043 Binding of HP 52 0.30 26.56 7.76
8 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97
9 INT63177 Regulation of HP 71 0.44 39.48 5.86
10 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75
11 INT23045 Positive_regulation of Hbb 31 0.64 19.35 4.54
12 INT44578 Binding of Hbb 19 0.48 3.12 4.2
13 INT192970 Negative_regulation of Hp 7 0.22 6.99 4.06
14 INT23044 Gene_expression of Hbb 13 0.43 5.77 3.1
15 INT21299 Negative_regulation of Hp 14 0.44 10.97 2.97
16 INT15288 Regulation of Hp 11 0.60 3.68 2.89
17 INT192964 Positive_regulation of Hp 7 0.28 2 2.75
18 INT4647 Regulation of Hbb 10 0.60 5.28 2.66
19 INT33243 Localization of HP 17 0.12 9.7 2.2
20 INT130392 Positive_regulation of Gene_expression of HP 7 0.69 7.34 1.9
21 INT192968 Positive_regulation of Gene_expression of Hp 2 0.28 1.34 1.44
22 INT273128 Protein_catabolism of Hp 3 0.47 2.2 1.39
23 INT49978 Localization of Hbb 4 0.39 1.11 1.29
24 INT3402 Positive_regulation of Positive_regulation of Hp 2 0.49 1.05 1
25 INT273124 Positive_regulation of Negative_regulation of Hp 1 0.26 0.54 0.91
26 INT110548 Regulation of Gene_expression of Hbb 2 0.16 0.65 0.81
27 INT273125 Positive_regulation of Localization of Hp 1 0.26 0.45 0.78
28 INT273127 Localization of Hp 1 0.39 0.45 0.77
29 INT35804 Regulation of Gene_expression of Hp 3 0.34 0.68 0.75
30 INT295416 Regulation of Positive_regulation of Hbb 1 0.04 1.92 0.73
31 INT295417 Negative_regulation of Positive_regulation of Hbb 1 0.04 1.92 0.72
32 INT192963 Transcription of Hp 2 0.39 1.32 0.67
33 INT192969 Negative_regulation of Gene_expression of Hp 1 0.32 1.06 0.59
34 INT273122 Positive_regulation of Positive_regulation of Hp 1 0.26 0.08 0.58
35 INT273126 Positive_regulation of Binding of Hp 1 0.26 0.08 0.58
36 INT164537 Negative_regulation of Gene_expression of Hbb 2 0.06 1.47 0.55
37 INT192966 Positive_regulation of Transcription of Hp 1 0.38 0.82 0.55
38 INT19212 Positive_regulation of Gene_expression of Hp 5 0.15 1.47 0.46
39 INT128793 Gene_expression of HBB 16 0.78 10.69 0.42
40 INT206454 Positive_regulation of Localization of HP 2 0.05 0.82 0.39
41 INT101790 Positive_regulation of Positive_regulation of Hbb 2 0.25 1.82 0.38
42 INT183920 Localization of Hp 1 0.29 0.93 0.33
43 INT45869 Negative_regulation of Gene_expression of Hp 1 0.42 0.65 0.31
44 INT183911 Negative_regulation of Phosphorylation of Hp 1 0.17 0.86 0.3
45 INT46932 Positive_regulation of Binding of HP 1 0.36 1.67 0.28
46 INT183919 Positive_regulation of Phosphorylation of Hp 1 0.20 0.8 0.28
47 INT183914 Phosphorylation of Hp 1 0.32 0.78 0.27
48 INT103580 Negative_regulation of Negative_regulation of HP 1 0.01 0.71 0.24
49 INT103581 Negative_regulation of Regulation of HP 1 0.02 0.77 0.22
50 INT213242 Negative_regulation of Gene_expression of HP 3 0.04 0.88 0.17
51 INT189236 Transcription of HP 4 0.28 3.07 0.16
52 INT66444 Regulation of Gene_expression of HP 4 0.45 3.48 0.15
53 INT156610 Negative_regulation of HBB 2 0.37 1.25 0.15
54 INT213241 Regulation of Regulation of HP 2 0.03 1.26 0.12
55 INT344957 Regulation of Negative_regulation of HP 1 0.07 2.9 0.08
56 INT304199 Negative_regulation of Positive_regulation of HP 1 0.04 1.72 0.08
57 INT166835 Regulation of HBB 1 0.02 1.08 0.08
58 INT107290 Regulation of Positive_regulation of HP 1 0.33 0.07 0.07
59 INT164958 Regulation of Gene_expression of HBB 1 0.44 0.59 0.07
60 INT230731 Positive_regulation of Negative_regulation of Hbb 1 0.01 0.52 0.07
61 INT128794 Negative_regulation of Gene_expression of HBB 1 0.59 5.98 0.06
62 INT38615 Positive_regulation of Negative_regulation of HP 1 0.01 0.64 0.04
63 INT204158 Positive_regulation of Gene_expression of Hbb 1 0.02 0.57 0.04
64 INT308562 Regulation of Localization of HP 2 0.07 2.11 0.03
65 INT207238 Binding of HBB 4 0.36 1.13 0
66 INT206452 Negative_regulation of Binding of HP 2 0.04 0.84 0
67 INT213240 Positive_regulation of Regulation of HP 2 0.02 1.05 0
68 INT157703 Positive_regulation of Positive_regulation of HP 2 0.42 0.76 0
69 INT206443 Phosphorylation of HP 1 0.06 0 0
70 INT189276 Positive_regulation of HBB 1 0.42 0 0
71 INT50455 Positive_regulation of Regulation of Hp 1 0.08 0.08 0
72 INT207234 Transcription of HBB 1 0.28 0 0
73 INT247471 Negative_regulation of Binding of Hbb 1 0.03 0.95 0
74 INT320049 Regulation of Binding of Hbb 1 0.02 0 0
75 INT279986 Protein_catabolism of HP 1 0.18 0.23 0
76 INT318136 Positive_regulation of Gene_expression of HBB 1 0.04 2.65 0
77 INT210076 Localization of HBB 1 0.15 0 0
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