GO:0031904

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Name endosome lumen
Categary Component
Go Slim No
Go Link GO:0031904
Unique Molecular Interactions 307
Total Molecular Interactions 396
Total Single Events 6107
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endosome lumen. They are ordered first by their pain relevance and then by number of times they were reported for endosome lumen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT42728 Binding of PRLR and Cpe 1 0.00 0 2.91
2 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
3 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
4 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
5 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
6 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
7 INT70028 LTA Regulation of PRF1 1 0.02 1.42 1.21
8 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
9 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 0.04 1.42 1.21
10 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
11 INT70042 LTA Regulation of Negative_regulation of PRF1 1 0.02 1.42 1.21
12 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
13 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
14 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
15 INT70044 IL12A Regulation of PRF1 1 0.04 1.42 1.21
16 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
17 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
18 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
19 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
20 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
21 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
22 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
23 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
24 INT41165 Gtf3a Regulation of INS 1 0.00 0.15 0.74
25 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
26 INT31643 POMC Regulation of INS 1 0.59 0.62 0.73
27 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
28 INT29847 INS Regulation of Localization of AVP 1 0.23 0.24 0.59
29 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
30 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
31 INT103165 NGF Positive_regulation of Localization of INS 1 0.05 0 0.58
32 INT29252 Regulation of INS Positive_regulation of GH1 1 0.26 0.08 0.54
33 INT29253 INS Positive_regulation of GH1 1 0.44 0.08 0.53
34 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
35 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
36 INT101001 GHRH Regulation of Localization of INS 1 0.28 0 0.47
37 INT151890 Binding of PRLR and Adarb1 1 0.00 0 0.45
38 INT188564 IRF6 Positive_regulation of Gene_expression of PRF1 1 0.01 0.44 0.44
39 INT188562 IRF6 Regulation of Gene_expression of PRF1 1 0.01 0.7 0.43
40 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4
41 INT285725 Binding of IGF1R and INS 1 0.27 0.07 0.4
42 INT29052 Binding of INS and INSRR 1 0.02 0.23 0.4
43 INT29053 Regulation of Binding of INS and INSRR 1 0.01 0.24 0.4
44 INT78621 PRL Positive_regulation of Localization of INS 2 0.06 0.5 0.39
45 INT291256 INS Negative_regulation of Positive_regulation of Mdk 1 0.01 1.65 0.39
46 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
47 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37
48 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
49 INT89386 INS Positive_regulation of Phosphorylation of AKT1 3 0.43 1.48 0.36
50 INT4382 RIPK2 Regulation of INS 1 0.12 0.58 0.36
51 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36
52 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
53 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35
54 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34
55 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34
56 INT183793 INS Negative_regulation of Binding of Ros1 1 0.16 1.66 0.34
57 INT183785 INS Positive_regulation of Gene_expression of NFKBIB 1 0.03 1.83 0.34
58 INT183780 INS Negative_regulation of Gene_expression of CYBB 1 0.02 1.74 0.34
59 INT4381 RIPK2 Positive_regulation of Localization of INS 1 0.13 0.53 0.34
60 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34
61 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33
62 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32
63 INT238895 Binding of CRP and INS 1 0.00 0.93 0.32
64 INT62616 Regulation of Binding of PRLR and ST14 1 0.00 0 0.31
65 INT62615 Binding of PRLR and ST14 1 0.00 0 0.31
66 INT191240 SAE1 Regulation of Localization of INS 1 0.08 1.15 0.3
67 INT51275 IGF1 Negative_regulation of INS 2 0.35 0.98 0.29
68 INT291202 Positive_regulation of INS Positive_regulation of AKT1 1 0.01 0.76 0.29
69 INT71550 GTPBP4 Regulation of Localization of INS 1 0.00 0.16 0.28
70 INT291201 Regulation of INS Positive_regulation of GOPC 1 0.00 0.35 0.28
71 INT291200 INS Positive_regulation of GOPC 1 0.01 0.3 0.28
72 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27
73 INT224406 INS Regulation of Localization of PYY 1 0.11 0.27 0.27
74 INT224405 INS Regulation of Localization of CCK 1 0.12 0.27 0.27
75 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
76 INT74433 Binding of INS and Cpe 2 0.03 0 0.25
77 INT291261 INS Positive_regulation of Phosphorylation of Mdk 1 0.01 0.28 0.25
78 INT309888 INS Positive_regulation of Gene_expression of FAAH 1 0.04 1.19 0.25
79 INT242875 INS Negative_regulation of Gene_expression of TLR4 1 0.11 1.41 0.24
80 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23
81 INT87750 IGFBP3 Negative_regulation of INS 1 0.11 0.86 0.23
82 INT63196 INS Positive_regulation of IL2 1 0.10 0.3 0.23
83 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
84 INT63195 INS Positive_regulation of CD8A 1 0.19 0.3 0.23
85 INT63199 INS Positive_regulation of PGR 1 0.11 0.3 0.23
86 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23
87 INT108808 Binding of IAPP and INS 1 0.32 1.36 0.23
88 INT25907 Binding of PRLR and Cish 1 0.00 0 0.23
89 INT151884 Binding of PRLR and YY1 1 0.01 0 0.23
90 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22
91 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22
92 INT214481 ROS1 Negative_regulation of Gene_expression of INS 1 0.00 0.37 0.22
93 INT39263 POMC Negative_regulation of INS 1 0.23 0.6 0.22
94 INT257397 Binding of FGD1 and INS 1 0.07 0.27 0.21
95 INT74437 Negative_regulation of Cpe Positive_regulation of Localization of INS 1 0.06 0 0.2
96 INT78622 POMC Positive_regulation of Localization of INS 1 0.07 0 0.2
97 INT3592 INS Positive_regulation of AVP 1 0.05 0.28 0.2
98 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2
99 INT3591 Negative_regulation of INS Positive_regulation of AVP 1 0.04 0.28 0.2
100 INT74439 Negative_regulation of Cpe Positive_regulation of INS 1 0.06 0 0.2
101 INT188566 TLR4 Regulation of Gene_expression of PRF1 1 0.01 0.2 0.2
102 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
103 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19
104 INT110717 CGA Positive_regulation of Localization of INS 1 0.03 0.5 0.19
105 INT68510 Binding of ATM and PRLR 1 0.01 0 0.19
106 INT32395 POMC Positive_regulation of INS 1 0.41 0.52 0.19
107 INT15523 INS Negative_regulation of FFAR1 1 0.02 0.35 0.16
108 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16
109 INT311227 INS Negative_regulation of HBA1 1 0.01 0.52 0.16
110 INT71548 ADRA2C Negative_regulation of Localization of INS 1 0.04 0.13 0.16
111 INT240620 Binding of INS and SHBG 4 0.12 3.35 0.15
112 INT207253 INS Negative_regulation of TXNIP 1 0.45 1.2 0.15
113 INT194136 Binding of HLA-E and INS 1 0.01 0.95 0.15
114 INT31641 POMC Regulation of Gene_expression of INS 1 0.26 0.25 0.15
115 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
116 INT141001 Negative_regulation of CPOX Regulation of Localization of INS 1 0.17 0.07 0.14
117 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
118 INT321408 INS Positive_regulation of EGR1 1 0.03 2.36 0.13
119 INT117371 SUCLA2 Positive_regulation of Localization of INS 1 0.03 0 0.13
120 INT117372 SUCLA2 Regulation of Localization of INS 1 0.02 0 0.13
121 INT321414 INS Positive_regulation of Transcription of EGR1 1 0.03 2.36 0.13
122 INT255710 Binding of INS and LOC691138 1 0.00 0.51 0.12
123 INT352501 PRKAB1 Positive_regulation of INS 1 0.04 1.36 0.12
124 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11
125 INT164923 INS Positive_regulation of GIP 1 0.43 0.18 0.11
126 INT188587 Trav6-3 Positive_regulation of Gene_expression of PRF1 1 0.00 0.21 0.11
127 INT267124 IGF1 Negative_regulation of Gene_expression of INS 2 0.14 0.18 0.1
128 INT26176 POMC Negative_regulation of Localization of INS 1 0.36 0.06 0.1
129 INT352500 Binding of FAT1 and INS 1 0.01 1.38 0.1
130 INT102248 INS Positive_regulation of Binding of HIF1A 1 0.13 0.96 0.1
131 INT350820 INS Regulation of SELS 1 0.13 1.11 0.1
132 INT27844 Binding of INS and Gh 1 0.03 0.1 0.1
133 INT262996 ADIPOQ Regulation of INS 1 0.13 1.25 0.1
134 INT102246 Binding of HIF1A and INS 1 0.07 0.96 0.1
135 INT27841 Binding of INS and GAL 1 0.04 0.1 0.1
136 INT267684 Binding of INS and ARID1B 3 0.10 6.08 0.09
137 INT164925 GIP Positive_regulation of Localization of INS 2 0.59 0.86 0.09
138 INT308585 Binding of APOB and PLA2G7 1 0.07 0.69 0.09
139 INT341235 Negative_regulation of INS Positive_regulation of Phosphorylation of Eif4ebp1 1 0.01 0.24 0.09
140 INT114414 TF Regulation of INS 1 0.18 0.09 0.09
141 INT109959 INS Positive_regulation of FBF1 1 0.27 0.24 0.09
142 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08
143 INT173130 Binding of INS and PPARA 2 0.04 1.8 0.08
144 INT172836 Binding of INS and T2dm2 1 0.00 1.65 0.08
145 INT291040 Binding of CFH and INS 1 0.25 1.32 0.08
146 INT273374 Binding of JAK2 and STAT3 1 0.24 0 0.07
147 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07
148 INT273368 Negative_regulation of Binding of JAK2 and STAT3 1 0.28 0 0.07
149 INT328306 GH1 Positive_regulation of Localization of INS 1 0.01 0.12 0.07
150 INT58648 Binding of HSD11B1 and INS 1 0.04 1.65 0.07
151 INT207824 KCNJ5 Regulation of Localization of INS 1 0.01 0 0.07
152 INT58649 Binding of INS and Serpine1 1 0.01 1.64 0.07
153 INT207552 Binding of GH1 and INS 1 0.23 0.55 0.07
154 INT273371 JAK2 Regulation of Protein_catabolism of SOCS1 1 0.01 0 0.06
155 INT311225 GLP1R Positive_regulation of Gene_expression of INS 1 0.49 0.33 0.06
156 INT202244 Igfbp1 Regulation of Localization of INS 1 0.06 0 0.06
157 INT325769 Binding of EPOR and Positive_regulation of Phosphorylation of JAK2 1 0.66 0 0.06
158 INT273365 JAK2 Regulation of SOCS1 1 0.01 0 0.06
159 INT328305 GHS Positive_regulation of Localization of INS 1 0.02 0.07 0.05
160 INT218614 INS Positive_regulation of Binding of IGF1 1 0.39 0.79 0.05
161 INT298733 INS Regulation of ACSBG1 1 0.00 0.97 0.05
162 INT238117 Positive_regulation of STAT3 Positive_regulation of Gene_expression of JAK2 1 0.11 0 0.05
163 INT328387 INS Negative_regulation of Gene_expression of Ghrl 1 0.01 0.6 0.05
164 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05
165 INT258084 Binding of IL6 and Regulation of Gene_expression of INS 1 0.11 0.62 0.05
166 INT280057 Zglp1 Positive_regulation of Transcription of INS 1 0.04 0.52 0.05
167 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05
168 INT218616 Binding of IGFBP3 and INS 1 0.07 0.68 0.05
169 INT238116 STAT3 Positive_regulation of Gene_expression of JAK2 1 0.16 0 0.05
170 INT112644 INS Negative_regulation of OVGP1 1 0.43 0 0.05
171 INT89384 Negative_regulation of INS Positive_regulation of AKT1 2 0.36 1.37 0.04
172 INT213263 INS Positive_regulation of EDN1 1 0.12 0.54 0.04
173 INT207846 Hypism Regulation of INS 1 0.06 1.14 0.04
174 INT350015 ARID1B Regulation of Localization of INS 1 0.03 2.6 0.04
175 INT341231 INS Positive_regulation of Phosphorylation of Eif4ebp1 1 0.01 0.13 0.04
176 INT314622 Binding of INS and Ex 1 0.08 0.44 0.04
177 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04
178 INT267155 Binding of INS and SUGT1 1 0.02 0.81 0.04
179 INT350121 INS Negative_regulation of Positive_regulation of SHBG 1 0.09 1.48 0.04
180 INT290180 Binding of APOB and PLTP 1 0.19 0.6 0.04
181 INT199212 Binding of IGFBP1 and INS 1 0.05 1.77 0.04
182 INT350118 INS Negative_regulation of SHBG 1 0.09 1.42 0.04
183 INT89385 INS Positive_regulation of Phosphorylation of PTK2B 1 0.15 0.59 0.04
184 INT202231 Binding of IGF1 and INS 2 0.28 1.38 0.03
185 INT352519 INS Positive_regulation of Localization of Slc2a4 1 0.07 0.97 0.03
186 INT207554 GH1 Negative_regulation of Phosphorylation of INS 1 0.26 0.28 0.03
187 INT230854 INS Regulation of Positive_regulation of SNAP47 1 0.09 1.03 0.03
188 INT230851 INS Regulation of VCAM1 1 0.07 1.02 0.03
189 INT230423 INS Negative_regulation of Lipg 1 0.03 0.74 0.03
190 INT181618 NOS3 Positive_regulation of INS 1 0.02 0.59 0.03
191 INT285726 Binding of ALB and INS 1 0.22 0.61 0.03
192 INT242884 INS Regulation of SPI1 1 0.03 0.3 0.03
193 INT337728 ADAMTS2 Positive_regulation of Gene_expression of INS 1 0.02 0 0.03
194 INT228522 Tmem170b Positive_regulation of Localization of INS 1 0.01 0.66 0.03
195 INT207553 GH1 Negative_regulation of INS 1 0.27 0.28 0.03
196 INT235626 Binding of IARS and INS 1 0.08 0.15 0
197 INT247435 Binding of APOB and SNRNP70 1 0.04 2.2 0
198 INT246152 INS Regulation of S1PR2 1 0.02 0 0
199 INT246151 INS Negative_regulation of TXLNB 1 0.01 0 0
200 INT253085 NPPA Positive_regulation of INS 1 0.32 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for endosome lumen. They are ordered first by their pain relevance and then by number of times they were reported in endosome lumen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT812 Localization of INS 1026 0.81 515.6 145.31
2 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
3 INT251 Regulation of INS 398 0.62 232.47 55.04
4 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
5 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
6 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
7 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
8 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
9 INT14572 Binding of INS 205 0.48 175.43 13.38
10 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
11 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
12 INT53590 Gene_expression of PRF1 33 0.58 23.46 10.02
13 INT12367 Binding of PRLR 17 0.03 2.05 9.69
14 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
15 INT13313 Regulation of PRLR 7 0.07 1.65 4.77
16 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
17 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9
18 INT18825 Gene_expression of PRLR 8 0.40 2 3.47
19 INT78912 Positive_regulation of Prf1 6 0.49 1.26 3.45
20 INT20082 Positive_regulation of PRLR 6 0.29 4.27 3.03
21 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91
22 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9
23 INT70053 Positive_regulation of Gene_expression of PRF1 2 0.12 3.41 2.73
24 INT25646 Negative_regulation of PRLR 5 0.08 0.08 2.62
25 INT70052 Transcription of PRF1 4 0.41 3.1 2.58
26 INT113339 Binding of JAK2 6 0.40 5.31 2.4
27 INT34266 Negative_regulation of Binding of PRLR 3 0.01 0 2.35
28 INT3315 Negative_regulation of Positive_regulation of INS 31 0.57 14.73 2.27
29 INT14384 Gene_expression of Prf1 9 0.60 3.03 2.22
30 INT26177 Regulation of Regulation of INS 19 0.44 11.32 2.18
31 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
32 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
33 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86
34 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
35 INT9466 Binding of APOB 27 0.41 19.36 1.56
36 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
37 INT116900 Positive_regulation of PRF1 5 0.49 4 1.39
38 INT41595 Protein_catabolism of Prf1 1 0.11 0.89 1.35
39 INT20238 Regulation of APOB 9 0.61 11.52 1.26
40 INT109104 Positive_regulation of Protein_catabolism of INS 4 0.50 4.44 1.24
41 INT70055 Negative_regulation of PRF1 1 0.11 1.38 1.17
42 INT3486 Positive_regulation of Regulation of INS 9 0.47 5.65 1.15
43 INT183046 Transcription of INS 25 0.70 11.14 1.13
44 INT20080 Localization of PRLR 2 0.03 0.42 1.12
45 INT58470 Negative_regulation of Binding of INS 14 0.43 7.2 1.01
46 INT41593 Negative_regulation of Protein_catabolism of Prf1 1 0.05 0.54 0.99
47 INT71376 Positive_regulation of Gene_expression of Prf1 1 0.03 1.08 0.98
48 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96
49 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
50 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81
51 INT12057 Regulation of Negative_regulation of INS 7 0.40 3.92 0.76
52 INT113342 Positive_regulation of Phosphorylation of JAK2 2 0.66 2.58 0.72
53 INT188585 Regulation of Gene_expression of PRF1 1 0.04 1.06 0.67
54 INT183789 Positive_regulation of Phosphorylation of INS 5 0.50 4.87 0.64
55 INT14570 Regulation of Positive_regulation of INS 8 0.45 4.97 0.62
56 INT215752 Negative_regulation of Positive_regulation of Prf1 1 0.06 0.86 0.57
57 INT188581 Negative_regulation of Gene_expression of PRF1 1 0.04 1.07 0.57
58 INT14571 Regulation of Binding of INS 2 0.23 2.44 0.53
59 INT95375 Regulation of Transcription of PRLR 1 0.00 0 0.49
60 INT95377 Regulation of Gene_expression of PRLR 1 0.00 0 0.49
61 INT95376 Transcription of PRLR 1 0.00 0 0.49
62 INT213286 Positive_regulation of Binding of INS 6 0.50 4.85 0.45
63 INT213272 Negative_regulation of Phosphorylation of INS 7 0.40 9.13 0.44
64 INT80754 Localization of PRF1 6 0.78 2.78 0.42
65 INT14569 Positive_regulation of Negative_regulation of INS 4 0.36 3.52 0.37
66 INT183066 Positive_regulation of Transcription of INS 8 0.49 5.31 0.34
67 INT83352 Positive_regulation of Negative_regulation of APOB 1 0.01 0.69 0.31
68 INT109451 Binding of PRF1 2 0.35 2.25 0.27
69 INT20081 Positive_regulation of Localization of PRLR 1 0.03 0.07 0.27
70 INT207293 Negative_regulation of Negative_regulation of INS 12 0.49 6 0.26
71 INT298428 Regulation of Positive_regulation of PRF1 1 0.26 1.55 0.26
72 INT303972 Positive_regulation of Gene_expression of JAK2 2 0.63 1.3 0.24
73 INT83230 Negative_regulation of Prf1 2 0.35 0.29 0.23
74 INT62617 Positive_regulation of Positive_regulation of PRLR 1 0.01 0 0.19
75 INT62274 Negative_regulation of Gene_expression of APOB 4 0.32 5.9 0.16
76 INT277049 Regulation of Binding of APOB 1 0.27 0.91 0.16
77 INT189998 Regulation of Prf1 2 0.22 0.44 0.1
78 INT312354 Regulation of Gene_expression of JAK2 1 0.25 1.17 0.1
79 INT228295 Negative_regulation of Transcription of INS 2 0.43 1.1 0.07
80 INT239409 Transcription of APOB 3 0.65 1.86 0.06
81 INT310747 Regulation of JAK2 2 0.33 1.58 0.05
82 INT255451 Positive_regulation of Positive_regulation of APOB 2 0.37 1.91 0.05
83 INT238202 Negative_regulation of Localization of JAK2 1 0.09 0 0.05
84 INT238200 Localization of JAK2 1 0.16 0 0.05
85 INT239411 Localization of APOB 10 0.76 5.71 0.04
86 INT246579 Negative_regulation of Localization of APOB 1 0.05 0.23 0.04
87 INT238199 Positive_regulation of Positive_regulation of JAK2 1 0.10 0 0.03
88 INT252743 Protein_catabolism of APOB 1 0.01 1.68 0.03
89 INT252758 Positive_regulation of Protein_catabolism of APOB 1 0.01 0.98 0.03
90 INT116901 Positive_regulation of Transcription of PRF1 2 0.36 0.4 0
91 INT183060 Regulation of Transcription of INS 2 0.44 0.34 0
92 INT255450 Positive_regulation of Binding of APOB 1 0.37 2.88 0
93 INT229627 Negative_regulation of Negative_regulation of APOB 1 0.31 0.26 0
94 INT238196 Negative_regulation of Binding of JAK2 1 0.09 0 0
95 INT219797 Localization of Prf1 1 0.61 0.1 0
96 INT219795 Regulation of Gene_expression of Prf1 1 0.37 0.06 0
97 INT350506 Protein_catabolism of JAK2 1 0.48 1.55 0
98 INT320539 Negative_regulation of Phosphorylation of JAK2 1 0.26 0.46 0
99 INT239410 Regulation of Localization of APOB 1 0.25 0.52 0
100 INT306793 Negative_regulation of Positive_regulation of APOB 1 0.27 0.33 0
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