GO:0031965

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Name nuclear membrane
Categary Component
Go Slim No
Go Link GO:0031965
Unique Molecular Interactions 1031
Total Molecular Interactions 1452
Total Single Events 13787
Pain Genes Associated 78

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nuclear membrane. They are ordered first by their pain relevance and then by number of times they were reported for nuclear membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
3 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
4 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
5 INT48162 RIMS3 Regulation of Localization of LTC4S 1 0.10 2.14 3.25
6 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
7 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64
8 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
9 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
10 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79
11 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
12 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65
13 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
14 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
15 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
16 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
17 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
18 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
19 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54
20 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
21 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
22 INT144454 Binding of DMPK and GPM6A 1 0.00 0 1.45
23 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
24 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
25 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
26 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
27 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
28 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
29 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
30 INT21424 Binding of Penk and Gtpbp4 1 0.02 0.16 1.2
31 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2
32 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
33 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 0.03 2.4 1.18
34 INT35399 Binding of Alox5 and Mthfs 1 0.01 0 1.14
35 INT68160 Alox5 Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.13
36 INT110671 Binding of Cnr1 and Alox5 1 0.07 0.2 1.13
37 INT68164 Mthfs Positive_regulation of Positive_regulation of Alox5 1 0.00 0.64 1.13
38 INT68167 Alox5 Positive_regulation of Positive_regulation of Mthfs 1 0.00 0.64 1.13
39 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
40 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13
41 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
42 INT68156 Pla2g1b Positive_regulation of Positive_regulation of Alox5 1 0.03 0.64 1.13
43 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
44 INT142572 D5Pas1 Negative_regulation of Nos1 2 0.02 0.14 1.11
45 INT317527 Binding of Hint1 and Nos1 1 0.27 0.1 1.11
46 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1
47 INT108546 BCL2L10 Regulation of MAPKAPK5 1 0.03 1.22 1.1
48 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05
49 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03
50 INT119914 Olr1714 Negative_regulation of Nos1 1 0.02 0.47 1.01
51 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
52 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
53 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
54 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
55 INT25111 Binding of PTGDS and PLEKHM1 1 0.01 0 0.97
56 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
57 INT203162 PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 1.47 0.94
58 INT126766 Binding of PTGDS and PTGDR2 4 0.40 1.62 0.93
59 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
60 INT123023 Ednra Regulation of Adarb1 1 0.00 0 0.93
61 INT123024 Csf2 Regulation of Ednra 1 0.06 0 0.92
62 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
63 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
64 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9
65 INT317530 Negative_regulation of Binding of Nos1 and Oprm1 1 0.21 0.06 0.9
66 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
67 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
68 INT57746 Il1 Regulation of Gene_expression of Ltc4s 1 0.36 0.33 0.88
69 INT116107 CDK4 Positive_regulation of Phosphorylation of EID1 1 0.01 0.32 0.86
70 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
71 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
72 INT120825 Adcyap1 Positive_regulation of Localization of Nos1 1 0.26 0.62 0.85
73 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
74 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
75 INT128702 Ednra Regulation of EDNRA 1 0.00 0.58 0.84
76 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
77 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
78 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
79 INT352201 Negative_regulation of ALOX5 Negative_regulation of Cpox 1 0.02 0.89 0.81
80 INT349657 Nos2 Regulation of Regulation of Nos1 1 0.24 0.9 0.8
81 INT142454 Npff Positive_regulation of Gtpbp4 1 0.56 0 0.78
82 INT203164 PTGER2 Regulation of ALOX5 1 0.00 0.9 0.78
83 INT142455 Binding of Npff and Gtpbp4 1 0.40 0 0.78
84 INT203171 PTGER2 Negative_regulation of ALOX5 1 0.01 0.89 0.77
85 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
86 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
87 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 0.17 0.39 0.76
88 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 0.32 0.39 0.76
89 INT108611 Adra2a Regulation of Gene_expression of Nos1 1 0.10 0 0.75
90 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
91 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
92 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
93 INT159569 Negative_regulation of Alox5 Negative_regulation of Gene_expression of Fos 1 0.37 0.4 0.7
94 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
95 INT121697 IL4I1 Positive_regulation of Gene_expression of MMP3 1 0.06 0.27 0.7
96 INT106154 Calca Positive_regulation of Nos1 1 0.29 0.2 0.68
97 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
98 INT347962 Cpox Negative_regulation of Positive_regulation of Nos1 1 0.02 0.59 0.67
99 INT113931 Mors1 Positive_regulation of Gtpbp4 1 0.02 0 0.67
100 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
101 INT169213 Binding of EGFR and CARTPT 1 0.00 0.22 0.67
102 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66
103 INT220035 Nos1 Positive_regulation of Nos2 1 0.29 0.45 0.66
104 INT153921 Positive_regulation of Adra2a Regulation of Ednrb 1 0.01 0 0.66
105 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
106 INT78663 Dlst Regulation of Nos1 1 0.19 0.91 0.65
107 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
108 INT219921 EDNRA Negative_regulation of Trpv1 1 0.13 0.36 0.63
109 INT38905 Ptgfr Regulation of Ptgds 1 0.20 0 0.63
110 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
111 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
112 INT164286 Alox5ap Positive_regulation of Cysltr2 1 0.19 1.11 0.61
113 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
114 INT164285 Ltc4s Positive_regulation of Cysltr2 1 0.20 1.11 0.61
115 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
116 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
117 INT164283 Ltb4r Positive_regulation of Ltc4s 1 0.37 1.1 0.6
118 INT164284 Ltb4r Positive_regulation of Alox5ap 1 0.34 1.1 0.6
119 INT270100 Negative_regulation of Binding of ALOX5 and PLA2G2A 1 0.01 0.51 0.59
120 INT161387 Binding of PNOC and GTPBP4 1 0.03 1.05 0.59
121 INT35398 Fnd3c2 Negative_regulation of Binding of Alox5 1 0.00 0 0.58
122 INT335432 Ltc4s Regulation of Cysltr2 1 0.11 0.38 0.58
123 INT335436 Ltc4s Regulation of Gene_expression of Cysltr2 1 0.18 0.38 0.58
124 INT169286 CNR1 Positive_regulation of Phosphorylation of EGFR 1 0.45 0.18 0.57
125 INT270102 ALOX5 Negative_regulation of PLA2G2A 1 0.01 0.49 0.57
126 INT142571 Pnoc Positive_regulation of Nos1 1 0.52 0.06 0.57
127 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53
128 INT97425 Prkcg Regulation of Regulation of Nos1 1 0.06 0 0.53
129 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52
130 INT130157 Pomc Regulation of Gene_expression of Ednrb 1 0.14 0 0.52
131 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52
132 INT317537 Oprm1 Positive_regulation of Phosphorylation of Nos1 1 0.16 0 0.5
133 INT81004 Htr1a Positive_regulation of Gtpbp4 1 0.20 0 0.5
134 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
135 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
136 INT90121 Nos1 Regulation of Fos 1 0.27 0.25 0.49
137 INT251163 Gene_expression of Alox5 Positive_regulation of Trpv1 1 0.02 0.11 0.48
138 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
139 INT136141 Hsd11b1 Positive_regulation of Gene_expression of Agrp 1 0.64 0.2 0.47
140 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
141 INT257220 Binding of Nos1 and Flvcr2 1 0.00 0.17 0.47
142 INT312112 ELANE Regulation of Transcription of ALOX5 1 0.09 0.82 0.47
143 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
144 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
145 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
146 INT193219 Binding of LTC4S and CYSLTR2 2 0.28 2.2 0.44
147 INT94093 Pnoc Positive_regulation of EDNRA 1 0.03 0.1 0.44
148 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
149 INT158267 Olr1745 Negative_regulation of Alox5 1 0.05 0.94 0.43
150 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
151 INT159349 Zfp956 Negative_regulation of Nos1 1 0.03 0.61 0.43
152 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
153 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
154 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
155 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
156 INT111410 Nos1 Regulation of Vip 1 0.00 0 0.41
157 INT146273 Binding of Nos1 and Rasd1 1 0.34 0.18 0.41
158 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
159 INT203163 LTB4R Regulation of Gene_expression of ALOX5 1 0.00 0.98 0.41
160 INT111409 Nos1 Regulation of Gene_expression of Vip 1 0.01 0 0.41
161 INT159571 Trpv1 Positive_regulation of Gene_expression of Alox5 1 0.37 0.58 0.4
162 INT264522 Binding of GPER and PTGDS 1 0.03 1.22 0.4
163 INT334763 Ednra Positive_regulation of Gabrg1 1 0.01 0 0.4
164 INT56876 Regulation of Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
165 INT312123 ELANE Positive_regulation of ALOX5 1 0.09 0.74 0.4
166 INT56875 Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
167 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
168 INT264525 Binding of PTGDS and PTGFR 1 0.02 1.22 0.39
169 INT146272 Binding of Nos1 and Nos1ap 1 0.28 0.2 0.39
170 INT77683 Ednra Negative_regulation of LH 1 0.03 0.23 0.39
171 INT203167 Gene_expression of PTGER2 Positive_regulation of Gene_expression of ALOX5AP 1 0.03 0.67 0.38
172 INT201274 Car2 Regulation of Gene_expression of Nos1 1 0.05 1.15 0.38
173 INT272751 EGFR Regulation of Negative_regulation of Prkca 1 0.01 0 0.38
174 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
175 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
176 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
177 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
178 INT264527 IL1B Positive_regulation of Gene_expression of PTGDS 1 0.07 0.75 0.38
179 INT339506 Binding of Irak1 and Traf6 1 0.03 0.12 0.37
180 INT117184 GOLPH3 Regulation of CXCR4 1 0.30 0.29 0.37
181 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
182 INT117182 GOLPH3 Regulation of Binding of CXCR4 1 0.50 0.29 0.37
183 INT320591 Ca2 Positive_regulation of Nos1 1 0.07 0.09 0.37
184 INT80444 Binding of EDNRA and SPR 1 0.05 0.1 0.36
185 INT152315 Ifng Regulation of Ednrb 1 0.19 0.22 0.36
186 INT152313 Il18 Regulation of Ednrb 1 0.30 0.22 0.36
187 INT312102 Binding of ALOX5 and ALOX5AP 1 0.10 0.65 0.36
188 INT241072 Tpr Positive_regulation of Regulation of Oprm1 1 0.01 0.08 0.36
189 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
190 INT277985 Epo Positive_regulation of Epc1 1 0.03 1.36 0.36
191 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
192 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
193 INT126767 Positive_regulation of Binding of PTGDS and PTGDR2 1 0.54 0.3 0.35
194 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35
195 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
196 INT105768 Binding of Nos1 and Nqo1 1 0.00 0.26 0.34
197 INT144448 Nqo1 Regulation of Nos1 1 0.11 0.09 0.34
198 INT144450 Regulation of Nqo1 Regulation of Nos1 1 0.11 0.1 0.34
199 INT39208 ALOX5 Regulation of Gene_expression of IL2 1 0.04 0.06 0.34
200 INT264521 PTGDS Negative_regulation of Positive_regulation of MMP1 1 0.06 1.42 0.34

Single Events

The table below shows the top 100 pain related interactions that have been reported for nuclear membrane. They are ordered first by their pain relevance and then by number of times they were reported in nuclear membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76
2 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
3 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61
4 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87
5 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
6 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64
7 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
8 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97
9 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
10 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
11 INT5418 Negative_regulation of Alox5 108 0.57 42.09 31.17
12 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
13 INT9053 Negative_regulation of ALOX5 97 0.58 40.34 29.94
14 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
15 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
16 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
17 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
18 INT4809 Gene_expression of PTGDS 103 0.76 52.94 24.01
19 INT49172 Regulation of Nos1 43 0.52 27.53 23.66
20 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
21 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
22 INT17442 Gene_expression of ALOX5 110 0.75 51.55 18.29
23 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53
24 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38
25 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
26 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
27 INT114025 Transcription of Nos1 20 0.70 16.48 15.63
28 INT195414 Gene_expression of ALOX5AP 65 0.72 31.22 15.25
29 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
30 INT64112 Regulation of Gene_expression of Nos1 22 0.62 21.45 14.76
31 INT23344 Gene_expression of Alox5 60 0.75 28.2 13.82
32 INT7997 Gene_expression of Ltc4s 51 0.76 34.28 13.8
33 INT21421 Regulation of Gtpbp4 15 0.30 2.7 13.49
34 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
35 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
36 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79
37 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
38 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
39 INT80251 Binding of Nos1 21 0.30 8.24 11.31
40 INT4804 Positive_regulation of Gene_expression of PTGDS 10 0.68 21.43 11.14
41 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
42 INT110017 Phosphorylation of Nos1 12 0.60 1.64 10.3
43 INT67915 Negative_regulation of Gtpbp4 18 0.33 6.31 10.17
44 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
45 INT139443 Positive_regulation of GCH1 9 0.69 8.2 10.14
46 INT17421 Negative_regulation of Alox5 41 0.57 15.23 10.05
47 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68
48 INT4808 Gene_expression of LTC4S 37 0.73 18.36 9.62
49 INT9889 Gene_expression of Alox5 34 0.63 20.83 8.85
50 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71
51 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
52 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
53 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
54 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
55 INT84672 Negative_regulation of Positive_regulation of Nos1 12 0.48 3.76 8.27
56 INT30382 Negative_regulation of Ednra 21 0.42 12.06 8.19
57 INT114023 Positive_regulation of Transcription of Nos1 7 0.60 5.35 8.06
58 INT71381 Localization of Nos1 33 0.79 11.46 8.05
59 INT77804 Regulation of Ednra 9 0.39 2.71 7.94
60 INT68434 Gene_expression of Gtpbp4 15 0.54 5.5 7.91
61 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
62 INT54978 Binding of EDNRA 36 0.41 14.97 7.86
63 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
64 INT4807 Localization of LTC4S 23 0.58 6.89 7.59
65 INT67170 Gene_expression of Ednra 22 0.65 9.35 7.57
66 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
67 INT152347 Binding of GCH1 8 0.37 6.13 7.36
68 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33
69 INT6341 Binding of Gtpbp4 11 0.44 1.54 7.3
70 INT77756 Positive_regulation of GTPBP4 16 0.11 2.6 7.29
71 INT4810 Localization of PTGDS 20 0.81 4.19 6.97
72 INT167049 Binding of Ednra 3 0.07 3.47 6.84
73 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
74 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
75 INT92741 Positive_regulation of Positive_regulation of Nos1 8 0.47 1.44 6.58
76 INT78178 Gene_expression of Ednrb 21 0.75 7.1 6.37
77 INT103723 Regulation of Positive_regulation of Gtpbp4 5 0.22 1.56 6.35
78 INT11154 Binding of EGFR 149 0.48 96.23 6.29
79 INT69499 Binding of Nos1 15 0.36 2.56 6.23
80 INT93658 Transcription of Nos1 16 0.72 6.85 6.16
81 INT163776 Regulation of GCH1 7 0.27 4.58 6.16
82 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
83 INT64111 Negative_regulation of Gene_expression of Nos1 22 0.57 8.96 6.02
84 INT677 Positive_regulation of CST3 20 0.67 17.47 6
85 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
86 INT257199 Positive_regulation of Phosphorylation of Nos1 2 0.45 0.68 5.78
87 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
88 INT84673 Localization of Nos1 19 0.80 5.01 5.62
89 INT7996 Gene_expression of Ptgds 18 0.64 6.47 5.51
90 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49
91 INT28164 Regulation of ALOX5 25 0.60 12.76 5.47
92 INT28165 Positive_regulation of ALOX5 38 0.47 10.8 5.37
93 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36
94 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32
95 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
96 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
97 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16
98 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
99 INT6577 Regulation of Alox5 18 0.47 9.19 5.06
100 INT10606 Localization of Ltc4s 16 0.75 10.14 5.05
101 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
102 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
103 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93
104 INT92858 Negative_regulation of Ednra 6 0.57 1.25 4.81
105 INT10605 Positive_regulation of Ltc4s 21 0.68 17.22 4.8
106 INT30355 Positive_regulation of Gene_expression of Alox5 10 0.67 14.61 4.69
107 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
108 INT246315 Localization of Ednra 22 0.15 2.73 4.64
109 INT15995 Positive_regulation of Alox5 18 0.49 3.94 4.63
110 INT21953 Binding of Ednra 12 0.33 4.72 4.56
111 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
112 INT29519 Gene_expression of Ednrb 8 0.66 1.99 4.55
113 INT92133 Negative_regulation of Ednrb 8 0.42 1.7 4.44
114 INT96748 Gene_expression of GOLPH3 7 0.58 5.13 4.42
115 INT148901 Binding of Sort1 2 0.39 3.65 4.32
116 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
117 INT27758 Positive_regulation of PTGDS 20 0.67 10.74 4.22
118 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
119 INT74203 Positive_regulation of Positive_regulation of Gtpbp4 6 0.50 0.33 4.13
120 INT74365 Positive_regulation of Alox5 19 0.47 11.03 4.04
121 INT152312 Positive_regulation of Ednrb 7 0.49 1.46 4.04
122 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95
123 INT20743 Positive_regulation of Gene_expression of Ltc4s 13 0.60 12.3 3.86
124 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
125 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
126 INT44254 Regulation of Gene_expression of ALOX5 12 0.43 7.06 3.65
127 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
128 INT148899 Regulation of Sort1 2 0.50 2.72 3.46
129 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45
130 INT134875 Phosphorylation of Nos1 5 0.70 1.21 3.44
131 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
132 INT115203 Negative_regulation of Positive_regulation of Ednra 5 0.33 1.27 3.32
133 INT135815 Transcription of Gch1 1 0.60 0 3.32
134 INT142568 Negative_regulation of Positive_regulation of Nos1 2 0.37 0.25 3.3
135 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
136 INT84222 Regulation of Ednrb 4 0.45 2.24 3.25
137 INT16159 Regulation of Ltc4s 11 0.38 2.52 3.21
138 INT10476 Binding of ALOX5 26 0.36 7.69 3.2
139 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
140 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
141 INT195415 Regulation of Gene_expression of ALOX5AP 10 0.45 6.43 3.13
142 INT117348 Regulation of EGFR 75 0.61 47.73 3.09
143 INT49971 Regulation of Ednra 10 0.35 2.4 3.06
144 INT30435 Gene_expression of Ei24 6 0.58 1.5 3.05
145 INT35448 Negative_regulation of Gene_expression of ALOX5 11 0.57 5.28 3.03
146 INT105884 Binding of Bcl2 19 0.35 15.67 3
147 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
148 INT4811 Positive_regulation of Gene_expression of LTC4S 5 0.65 3.29 2.92
149 INT93058 Positive_regulation of Gene_expression of Ednra 8 0.28 4.11 2.88
150 INT76342 Positive_regulation of Gene_expression of Alox5 9 0.56 5.29 2.87
151 INT172678 Gene_expression of NUPL2 20 0.75 5.06 2.85
152 INT195421 Positive_regulation of Gene_expression of ALOX5AP 12 0.49 5.17 2.82
153 INT150933 Negative_regulation of Positive_regulation of GCH1 3 0.58 1.8 2.77
154 INT76836 Positive_regulation of Ednra 6 0.55 2.65 2.72
155 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71
156 INT49169 Regulation of Negative_regulation of Nos1 3 0.45 4.67 2.7
157 INT209889 Gene_expression of TRAF6 13 0.63 6.85 2.67
158 INT156016 Binding of BCL2L1 10 0.36 7.42 2.64
159 INT108608 Positive_regulation of Positive_regulation of Nos1 8 0.49 1.66 2.58
160 INT150932 Positive_regulation of Gene_expression of GCH1 3 0.70 2.07 2.57
161 INT128774 Regulation of Gene_expression of Ednrb 3 0.46 1 2.56
162 INT25119 Binding of PTGDS 9 0.35 3.86 2.54
163 INT34905 Positive_regulation of Gene_expression of ALOX5 18 0.50 7.46 2.46
164 INT163544 Binding of Psen1 40 0.36 15.28 2.42
165 INT283973 Transcription of GCH1 1 0.61 1.99 2.33
166 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
167 INT117336 Gene_expression of Nek1 2 0.02 8.56 2.31
168 INT16089 Gene_expression of Ltc4s 11 0.77 3.37 2.29
169 INT144792 Negative_regulation of Transcription of Nos1 2 0.43 1.74 2.27
170 INT283975 Negative_regulation of Localization of GCH1 1 0.38 1.99 2.27
171 INT97748 Positive_regulation of BCL2L1 12 0.67 9.83 2.26
172 INT640 Regulation of CST3 9 0.60 4.04 2.26
173 INT91836 Negative_regulation of Gene_expression of BCL2L1 9 0.49 8.59 2.25
174 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
175 INT135827 Positive_regulation of Transcription of Gch1 1 0.58 0 2.2
176 INT102752 Positive_regulation of Gene_expression of BCL2L1 14 0.67 13.8 2.19
177 INT78177 Negative_regulation of Gene_expression of Ednrb 4 0.41 1.04 2.16
178 INT110016 Negative_regulation of Phosphorylation of Nos1 3 0.28 0.47 2.16
179 INT66881 Positive_regulation of Sort1 2 0.57 0.99 2.16
180 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
181 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
182 INT30436 Negative_regulation of Ei24 4 0.56 3.8 2.15
183 INT121884 Regulation of Binding of Nos1 2 0.33 1.63 2.15
184 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
185 INT138605 Negative_regulation of Phosphorylation of BCL2L10 3 0.26 2.28 2.13
186 INT138607 Phosphorylation of BCL2L10 3 0.36 2.27 2.1
187 INT26736 Localization of Alox5 7 0.49 3.72 2.09
188 INT83744 Gene_expression of SULT1E1 9 0.75 3.12 2.07
189 INT108982 Regulation of Gene_expression of Ptgds 6 0.51 1.64 2.07
190 INT101645 Regulation of Gene_expression of Bcl2l1 8 0.36 5.27 2.05
191 INT156677 Regulation of Gene_expression of Ednra 4 0.15 0.25 2.05
192 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
193 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
194 INT258637 Regulation of Gene_expression of GCH1 1 0.62 1.77 2.02
195 INT66882 Gene_expression of Sort1 3 0.73 0.64 1.97
196 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
197 INT20251 Binding of Alox5 7 0.32 5.33 1.93
198 INT68435 Regulation of Gene_expression of Gtpbp4 4 0.34 0.96 1.89
199 INT9297 Localization of Gtpbp4 4 0.17 0.88 1.89
200 INT65545 Localization of EGFR 35 0.79 20.8 1.88
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