GO:0031983

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Name vesicle lumen
Categary Component
Go Slim No
Go Link GO:0031983
Unique Molecular Interactions 68
Total Molecular Interactions 91
Total Single Events 924
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for vesicle lumen. They are ordered first by their pain relevance and then by number of times they were reported for vesicle lumen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
2 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
3 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
4 INT28079 POMC Regulation of ANPEP 1 0.08 0.16 0.66
5 INT259776 Fbn2 Regulation of Negative_regulation of Agtr1a 1 0.00 1.42 0.66
6 INT259768 Positive_regulation of Agtr1a Regulation of Etf1 1 0.00 1.32 0.62
7 INT19690 Enpep Regulation of Negative_regulation of Penk 1 0.28 0 0.54
8 INT79809 Binding of Agtr1a and Adra1a 1 0.02 0.23 0.53
9 INT321045 Anpep Positive_regulation of Protein_catabolism of Ptpn6 1 0.01 0.22 0.48
10 INT321046 Anpep Regulation of Negative_regulation of Hps4 1 0.02 0.25 0.43
11 INT321047 Anpep Regulation of Negative_regulation of Ptpn6 1 0.01 0.25 0.43
12 INT278932 Binding of Agtr1a and H3 1 0.00 0 0.39
13 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
14 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34
15 INT330121 Agtr1a Positive_regulation of Gene_expression of Bdkrb1 1 0.05 0.68 0.34
16 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32
17 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
18 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
19 INT297257 Agtr1a Positive_regulation of Agtr2 1 0.27 0.59 0.22
20 INT229360 Agt Positive_regulation of Agtr1a 2 0.48 1.26 0.2
21 INT230749 Crp Regulation of Agtr1a 1 0.07 1.33 0.19
22 INT224086 Binding of Agtr1a and Hspa8 1 0.00 0.1 0.19
23 INT51034 Slc30a2 Positive_regulation of Enpep 1 0.01 0 0.19
24 INT104702 KNG1 Negative_regulation of Anpep 1 0.11 0.47 0.19
25 INT224126 Binding of Hspa8 and Agtr1a 1 0.00 0.09 0.17
26 INT352290 Binding of Agtr1a and P2ry1 1 0.00 0 0.16
27 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14
28 INT293119 Agtr1a Regulation of Positive_regulation of Crh 1 0.12 0.37 0.14
29 INT293123 Agtr1a Regulation of Negative_regulation of Agt 1 0.14 0.25 0.14
30 INT110176 Nts Regulation of Negative_regulation of Agtr1a 1 0.24 0.09 0.12
31 INT229359 Agt Positive_regulation of Binding of Agtr1a 1 0.25 0.9 0.12
32 INT308585 Binding of APOB and PLA2G7 1 0.07 0.69 0.09
33 INT249994 Binding of Agtr1a and Igkv4-55 1 0.01 0.38 0.08
34 INT200641 Binding of ACE and Agtr1a 1 0.12 0.92 0.06
35 INT231395 Binding of HSD11B1 and Apob 1 0.27 1.18 0.04
36 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04
37 INT240623 Binding of CRP and Apob 1 0.01 0.52 0.04
38 INT290180 Binding of APOB and PLTP 1 0.19 0.6 0.04
39 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03
40 INT194486 Binding of SNRNP70 and Apob 1 0.00 0.64 0.03
41 INT247435 Binding of APOB and SNRNP70 1 0.04 2.2 0
42 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0
43 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0
44 INT171598 Binding of APOB and Lipg 1 0.01 0.63 0
45 INT340504 Agtr1a Negative_regulation of Phosphorylation of Pik3cb 1 0.06 1.16 0
46 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0
47 INT344880 Binding of ANPEP and Mapt 1 0.08 0.15 0
48 INT205393 MME Regulation of Gene_expression of ANPEP 1 0.26 1.49 0
49 INT298849 Binding of APOB and MCC 1 0.00 0.38 0
50 INT353802 Binding of APOE and Apob 1 0.05 0.83 0
51 INT210417 APOB Negative_regulation of CYP2D6 1 0.01 0 0
52 INT292135 Binding of Anpep and Rtn4r 1 0.01 0.91 0
53 INT298856 Binding of APOB and MTG1 1 0.00 0.38 0
54 INT70122 NAGLU Positive_regulation of Localization of Anpep 1 0.10 0 0
55 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0
56 INT277047 Binding of APOB and LDLR 1 0.25 0.82 0
57 INT205389 Binding of ANPEP and DCLK1 1 0.09 1.42 0
58 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0
59 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0
60 INT247438 Binding of APOB and SACM1L 1 0.28 2 0
61 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0
62 INT205392 Binding of ANPEP and PCSK1 1 0.06 1.4 0
63 INT229362 Negative_regulation of Agtr1a Positive_regulation of Positive_regulation of Agtr2 1 0.05 1 0
64 INT205391 MME Regulation of ANPEP 1 0.26 1.36 0
65 INT247440 Binding of APOA1 and APOB 1 0.28 1.02 0
66 INT352794 Binding of APOB and FGF21 1 0.01 1.98 0
67 INT298861 Binding of APOB and RAB7A 1 0.00 0.32 0
68 INT85010 Apo Regulation of Apob 1 0.00 0.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for vesicle lumen. They are ordered first by their pain relevance and then by number of times they were reported in vesicle lumen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5232 Negative_regulation of Enpep 56 0.57 3.25 26.7
2 INT79703 Gene_expression of Agtr1a 46 0.76 14.18 13.77
3 INT53038 Positive_regulation of Agtr1a 35 0.67 23.76 11.68
4 INT7350 Negative_regulation of Anpep 30 0.59 2.89 11.28
5 INT10982 Negative_regulation of Agtr1a 42 0.58 22.42 10.29
6 INT18941 Regulation of Enpep 17 0.55 2.56 9.38
7 INT11441 Negative_regulation of Anpep 18 0.59 3.73 7.51
8 INT24504 Localization of Anpep 19 0.80 3.44 6.23
9 INT3768 Negative_regulation of ANPEP 16 0.59 4.96 5.52
10 INT33291 Protein_catabolism of Enpep 15 0.85 0.51 5.41
11 INT9456 Gene_expression of Anpep 9 0.78 1.69 4.26
12 INT48518 Gene_expression of ANPEP 51 0.78 22.88 4.18
13 INT53040 Binding of Agtr1a 22 0.47 7.36 4.15
14 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
15 INT30238 Positive_regulation of Anpep 14 0.66 2.77 3.38
16 INT18477 Protein_catabolism of ANPEP 7 0.79 0.41 3.26
17 INT29333 Positive_regulation of Enpep 8 0.70 3.22 3.25
18 INT22492 Binding of Enpep 10 0.47 0.7 3.2
19 INT111195 Negative_regulation of Gene_expression of Agtr1a 7 0.58 3.2 3.16
20 INT30228 Protein_catabolism of Anpep 3 0.42 0.82 2.87
21 INT63418 Regulation of Agtr1a 8 0.44 3.67 2.43
22 INT24997 Protein_catabolism of Anpep 6 0.96 0 2.34
23 INT31796 Gene_expression of Enpep 5 0.65 0.42 2.32
24 INT18480 Positive_regulation of ANPEP 9 0.59 5.18 2.13
25 INT51570 Regulation of Anpep 6 0.43 1.7 2
26 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
27 INT48357 Positive_regulation of Anpep 7 0.39 2.04 1.75
28 INT9466 Binding of APOB 27 0.41 19.36 1.56
29 INT54366 Gene_expression of Anpep 6 0.77 1.38 1.52
30 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
31 INT83553 Positive_regulation of Positive_regulation of Agtr1a 3 0.59 4.12 1.37
32 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36
33 INT20238 Regulation of APOB 9 0.61 11.52 1.26
34 INT37330 Regulation of Binding of Enpep 1 0.27 0 1.26
35 INT32786 Localization of Enpep 4 0.68 0 1.16
36 INT148072 Gene_expression of Agtr1a 5 0.75 9.41 1.13
37 INT130814 Binding of ANPEP 8 0.48 4.83 1.05
38 INT31314 Positive_regulation of Negative_regulation of Enpep 3 0.35 0.18 1.02
39 INT84325 Regulation of Gene_expression of Anpep 2 0.62 0.06 1.02
40 INT79862 Negative_regulation of Gene_expression of ANPEP 3 0.38 1.67 0.98
41 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9
42 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
43 INT79861 Localization of ANPEP 4 0.62 0.54 0.86
44 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85
45 INT229710 Localization of Agtr1a 3 0.60 0.57 0.84
46 INT10828 Regulation of Apob 7 0.39 7.55 0.83
47 INT213960 Localization of Anpep 1 0.09 0.28 0.83
48 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78
49 INT45661 Negative_regulation of Protein_catabolism of Enpep 2 0.36 0 0.76
50 INT18479 Negative_regulation of Protein_catabolism of ANPEP 1 0.34 0 0.69
51 INT111196 Negative_regulation of Negative_regulation of Agtr1a 2 0.42 0.49 0.65
52 INT147323 Transcription of Anpep 1 0.42 0.19 0.56
53 INT147321 Negative_regulation of Transcription of Anpep 1 0.34 0.2 0.56
54 INT159150 Negative_regulation of Positive_regulation of Agtr1a 1 0.38 0.72 0.56
55 INT52780 Positive_regulation of Protein_catabolism of Anpep 1 0.17 0 0.55
56 INT65215 Negative_regulation of Protein_catabolism of Anpep 1 0.36 0 0.53
57 INT124614 Transcription of ANPEP 3 0.52 1.1 0.51
58 INT28507 Regulation of ANPEP 4 0.26 1.84 0.5
59 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48
60 INT29334 Positive_regulation of Positive_regulation of Enpep 2 0.47 1.12 0.44
61 INT61867 Positive_regulation of Regulation of Anpep 1 0.36 0.33 0.44
62 INT46042 Positive_regulation of Protein_catabolism of Enpep 1 0.28 0 0.43
63 INT48356 Binding of Anpep 1 0.32 0 0.4
64 INT130815 Regulation of Gene_expression of ANPEP 3 0.62 1.88 0.37
65 INT48355 Transcription of Anpep 1 0.40 0 0.37
66 INT48358 Positive_regulation of Transcription of Anpep 1 0.35 0 0.37
67 INT224111 Phosphorylation of Agtr1a 1 0.01 0 0.35
68 INT339386 Negative_regulation of Gene_expression of Apob 3 0.43 1.91 0.34
69 INT83352 Positive_regulation of Negative_regulation of APOB 1 0.01 0.69 0.31
70 INT31740 Positive_regulation of Localization of Anpep 1 0.16 0 0.27
71 INT31741 Positive_regulation of Positive_regulation of Anpep 1 0.15 0 0.27
72 INT62618 Positive_regulation of Negative_regulation of Anpep 1 0.14 0 0.27
73 INT63417 Regulation of Negative_regulation of Agtr1a 1 0.26 0.1 0.25
74 INT147324 Positive_regulation of Gene_expression of Anpep 1 0.40 0.09 0.24
75 INT194472 Positive_regulation of Gene_expression of Apob 2 0.15 1.71 0.22
76 INT247022 Transcription of Agtr1a 2 0.46 1.47 0.21
77 INT230740 Regulation of Agtr1a 2 0.15 3.5 0.19
78 INT203836 Negative_regulation of Negative_regulation of Apob 1 0.18 0.45 0.19
79 INT62274 Negative_regulation of Gene_expression of APOB 4 0.32 5.9 0.16
80 INT277049 Regulation of Binding of APOB 1 0.27 0.91 0.16
81 INT209796 Positive_regulation of Agtr1a 1 0.15 0.56 0.15
82 INT203827 Localization of Apob 3 0.32 1.81 0.13
83 INT240040 Protein_catabolism of Apob 1 0.01 1.79 0.13
84 INT240041 Negative_regulation of Protein_catabolism of Apob 1 0.01 1.8 0.13
85 INT39824 Regulation of Protein_catabolism of Enpep 1 0.16 0 0.13
86 INT31309 Binding of Anpep 1 0.36 0 0.13
87 INT355657 Negative_regulation of Transcription of Agtr1a 1 0.38 1.17 0.13
88 INT355655 Regulation of Transcription of Agtr1a 1 0.29 1.15 0.13
89 INT99725 Negative_regulation of Agtr1a 5 0.57 1.03 0.12
90 INT194469 Positive_regulation of Apob 3 0.15 2.29 0.12
91 INT229356 Negative_regulation of Binding of Agtr1a 1 0.36 0.89 0.12
92 INT235511 Transcription of Apob 1 0.13 0.45 0.1
93 INT247024 Positive_regulation of Transcription of Agtr1a 1 0.19 0.33 0.09
94 INT209797 Regulation of Positive_regulation of Agtr1a 1 0.10 0.29 0.08
95 INT213136 Binding of Apob 2 0.03 2.76 0.07
96 INT213138 Negative_regulation of Binding of Apob 1 0.03 0.86 0.07
97 INT213137 Positive_regulation of Binding of Apob 1 0.04 0.87 0.07
98 INT179763 Localization of Apob 6 0.66 4.72 0.06
99 INT239409 Transcription of APOB 3 0.65 1.86 0.06
100 INT235517 Positive_regulation of Positive_regulation of Apob 1 0.10 0.58 0.06
101 INT183389 Regulation of Apob 4 0.01 5.17 0.05
102 INT255451 Positive_regulation of Positive_regulation of APOB 2 0.37 1.91 0.05
103 INT239411 Localization of APOB 10 0.76 5.71 0.04
104 INT182487 Positive_regulation of Gene_expression of Agtr1a 2 0.19 1.32 0.04
105 INT240615 Binding of Apob 2 0.07 0.85 0.04
106 INT341318 Positive_regulation of Gene_expression of ANPEP 1 0.45 1.97 0.04
107 INT36995 Negative_regulation of Negative_regulation of Enpep 1 0.37 0 0.04
108 INT341317 Positive_regulation of Binding of ANPEP 1 0.45 0.98 0.04
109 INT246579 Negative_regulation of Localization of APOB 1 0.05 0.23 0.04
110 INT325018 Regulation of Gene_expression of Apob 2 0.16 1.59 0.03
111 INT252743 Protein_catabolism of APOB 1 0.01 1.68 0.03
112 INT252758 Positive_regulation of Protein_catabolism of APOB 1 0.01 0.98 0.03
113 INT37798 Positive_regulation of Positive_regulation of Apob 1 0.06 1 0.03
114 INT146789 Regulation of Anpep 2 0.20 0 0
115 INT179761 Negative_regulation of Localization of Apob 2 0.40 2.9 0
116 INT255450 Positive_regulation of Binding of APOB 1 0.37 2.88 0
117 INT229627 Negative_regulation of Negative_regulation of APOB 1 0.31 0.26 0
118 INT241542 Regulation of Gene_expression of Apob 1 0.00 1.8 0
119 INT317658 Positive_regulation of Gene_expression of Apob 1 0.17 1.59 0
120 INT239410 Regulation of Localization of APOB 1 0.25 0.52 0
121 INT306793 Negative_regulation of Positive_regulation of APOB 1 0.27 0.33 0
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