GO:0031988

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Name membrane-bounded vesicle
Categary Component
Go Slim No
Go Link GO:0031988
Unique Molecular Interactions 684
Total Molecular Interactions 1056
Total Single Events 8580
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for membrane-bounded vesicle. They are ordered first by their pain relevance and then by number of times they were reported for membrane-bounded vesicle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
2 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
3 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
4 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
5 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
6 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
7 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
8 INT150787 ZNF398 Positive_regulation of Gene_expression of SPARC 1 0.13 1.02 1.05
9 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
10 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
11 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
12 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
13 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
14 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
15 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
16 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
17 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
18 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
19 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
20 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
21 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
22 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77
23 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
24 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
25 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
26 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71
27 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
28 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
29 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
30 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
31 INT185802 Binding of MMP7 and SPP1 1 0.33 1.71 0.68
32 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
33 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
34 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
35 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
36 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
37 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
38 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
39 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
40 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
41 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
42 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
43 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
44 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
45 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
46 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
47 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
48 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57
49 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
50 INT263756 Binding of Bmp1 and Neto1 1 0.30 0.11 0.54
51 INT150800 THBS3 Negative_regulation of SPARC 1 0.23 0.51 0.53
52 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
53 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
54 INT235390 HTR1A Regulation of BGLAP 1 0.03 0.23 0.51
55 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
56 INT185800 SPP1 Negative_regulation of Gene_expression of MMP1 1 0.26 1.03 0.49
57 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
58 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
59 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
60 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
61 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
62 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
63 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
64 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
65 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
66 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
67 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
68 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
69 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
70 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
71 INT235389 Binding of BGLAP and HTR1A 1 0.03 0.15 0.45
72 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
73 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
74 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
75 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
76 INT299041 SPARC Regulation of Gene_expression of NPEPPS 1 0.01 0.83 0.42
77 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
78 INT299040 Binding of COL7A1 and SPARC 1 0.02 0.7 0.42
79 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41
80 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
81 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
82 INT185811 SPP1 Positive_regulation of MMP3 1 0.14 0.83 0.38
83 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38
84 INT185814 Binding of MMP3 and SPP1 1 0.15 0.83 0.38
85 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
86 INT185804 MMP2 Positive_regulation of SPP1 1 0.15 0.88 0.37
87 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
88 INT185795 MMP7 Positive_regulation of SPP1 1 0.38 0.81 0.37
89 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
90 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37
91 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
92 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37
93 INT296306 Binding of BGLAP and SPIN1 1 0.05 1.69 0.37
94 INT185798 SPP1 Positive_regulation of Gene_expression of MMP2 1 0.26 0.87 0.37
95 INT185807 SPP1 Positive_regulation of MMP7 1 0.56 0.79 0.36
96 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
97 INT133307 Binding of CD44 and SPP1 5 0.26 2.6 0.35
98 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
99 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
100 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
101 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
102 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
103 INT242995 Agt Positive_regulation of Spp1 1 0.36 1.82 0.33
104 INT110691 Lta Positive_regulation of Gene_expression of VEGFA 1 0.24 0.48 0.33
105 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33
106 INT311997 Regulation of STAM Regulation of BGLAP 1 0.00 0.61 0.32
107 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
108 INT282420 Spp1 Positive_regulation of Ins1 1 0.20 1.25 0.32
109 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
110 INT311991 STAM Regulation of BGLAP 1 0.00 0.61 0.31
111 INT127974 RAX2 Positive_regulation of SPP1 1 0.03 1.49 0.31
112 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3
113 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
114 INT140386 Spp1 Positive_regulation of NFKB1 1 0.21 1.29 0.3
115 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3
116 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
117 INT140385 Spp1 Negative_regulation of FOXO3 1 0.04 1.29 0.3
118 INT179842 Sparc Regulation of Negative_regulation of Il11 1 0.15 0 0.29
119 INT185799 Binding of EGFR and SPP1 1 0.19 0.64 0.29
120 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29
121 INT185813 Binding of MMP7 and Positive_regulation of SPP1 1 0.46 0.85 0.28
122 INT185818 SPP1 Positive_regulation of Gene_expression of COL7A1 1 0.10 0.82 0.28
123 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
124 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28
125 INT344402 Binding of Crp and Spp1 1 0.05 2.92 0.28
126 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27
127 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27
128 INT103156 Tnf Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.94 0.27
129 INT287699 TNF Regulation of Binding of VEGFA 1 0.02 0.46 0.27
130 INT318551 Binding of VEGFA and Adamts1 1 0.13 1.13 0.27
131 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
132 INT248318 RETN Regulation of VEGFA 1 0.00 0.43 0.26
133 INT109538 Lox Negative_regulation of Transcription of VEGFA 1 0.30 0.69 0.26
134 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26
135 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26
136 INT103152 TNF Positive_regulation of Positive_regulation of VEGFA 1 0.09 0.93 0.26
137 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
138 INT126887 Protein_catabolism of SP4 Negative_regulation of Gene_expression of VEGFA 1 0.15 0.49 0.26
139 INT242991 Agt Positive_regulation of Gene_expression of Spp1 1 0.21 0.66 0.26
140 INT266803 Dlst Positive_regulation of VEGFA 1 0.01 0.96 0.25
141 INT109539 Lox Negative_regulation of VEGFA 1 0.40 0.68 0.25
142 INT145660 Zfp329 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.51 0.25
143 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25
144 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
145 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
146 INT98631 Negative_regulation of VEGFA Positive_regulation of EGR1 1 0.44 0.18 0.24
147 INT316815 Ctgf Negative_regulation of Gene_expression of Sparc 1 0.47 0.64 0.24
148 INT136798 Spp1 Regulation of Gene_expression of PTGS2 1 0.08 0.65 0.24
149 INT98630 VEGFA Positive_regulation of EGR1 1 0.52 0.18 0.24
150 INT329311 Spp1 Positive_regulation of IFN1@ 1 0.20 1.2 0.23
151 INT304323 VEGFA Positive_regulation of Gene_expression of Ptger2 1 0.27 0.16 0.23
152 INT118840 VEGFA Regulation of Positive_regulation of Mb 1 0.05 0.36 0.23
153 INT163403 VEGFA Positive_regulation of MMP2 1 0.52 0.13 0.23
154 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23
155 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23
156 INT329306 Spp1 Positive_regulation of Il12a 1 0.08 1.19 0.23
157 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23
158 INT299155 Smcp Negative_regulation of Spp1 1 0.00 0.7 0.22
159 INT245866 Binding of VEGFA and Fgf1 1 0.07 0.52 0.22
160 INT118838 Gene_expression of Vegfa Positive_regulation of Gene_expression of Mb 1 0.44 0.4 0.22
161 INT207456 LGALS3 Negative_regulation of Gene_expression of BGLAP 1 0.13 0.5 0.22
162 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22
163 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21
164 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
165 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21
166 INT316810 Sparc Regulation of Col1a1 1 0.13 0.48 0.21
167 INT114837 Il1b Negative_regulation of Vegfa 1 0.26 3.04 0.21
168 INT163096 Tlr2 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.16 0.21
169 INT242994 Adipoq Negative_regulation of Spp1 1 0.19 0.59 0.21
170 INT116469 VEGFA Positive_regulation of Amfr 1 0.01 1.39 0.21
171 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
172 INT116466 Vegfa Positive_regulation of Amfr 1 0.07 1.41 0.21
173 INT137610 Crh Positive_regulation of Localization of Vegfa 1 0.43 0.49 0.21
174 INT345196 Lpar2 Positive_regulation of Gene_expression of VEGFA 1 0.08 2.14 0.2
175 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2
176 INT236405 Mthfs Regulation of Gene_expression of VEGFA 1 0.00 0.25 0.2
177 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
178 INT189553 DCN Negative_regulation of Transcription of VEGFA 1 0.06 0.78 0.2
179 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19
180 INT175727 IL1B Regulation of VEGFA 2 0.04 0.7 0.19
181 INT329310 Spp1 Positive_regulation of Gene_expression of IFN1@ 1 0.48 0.88 0.19
182 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
183 INT282866 Bpifa2 Negative_regulation of Gene_expression of VEGFA 1 0.11 1.14 0.19
184 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
185 INT336892 Positive_regulation of Epc2 Positive_regulation of Localization of Spp1 1 0.00 0.62 0.19
186 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
187 INT336890 Positive_regulation of Epc2 Positive_regulation of Spp1 1 0.00 0.62 0.19
188 INT110692 Lta Regulation of Gene_expression of VEGFA 1 0.14 0.28 0.19
189 INT185805 SPP1 Regulation of MMP7 1 0.25 0.38 0.19
190 INT329309 Spp1 Regulation of Gene_expression of IFN1@ 1 0.26 0.82 0.19
191 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
192 INT304325 Positive_regulation of Ptger2 Positive_regulation of Gene_expression of VEGFA 1 0.25 0.23 0.19
193 INT337697 FGF2 Regulation of VEGFA 1 0.03 0.51 0.18
194 INT113809 Negative_regulation of Cpox Negative_regulation of Gene_expression of VEGFA 1 0.02 0.97 0.18
195 INT185816 SPP1 Positive_regulation of Positive_regulation of MMP7 1 0.46 0.36 0.18
196 INT337698 VEGFA Regulation of FGFR1 1 0.09 0.51 0.18
197 INT242993 Positive_regulation of Ppara Positive_regulation of Gene_expression of Spp1 1 0.24 0.66 0.18
198 INT330514 Vegfa Positive_regulation of VEGFA 1 0.18 0.5 0.18
199 INT185803 Binding of MMP11 and SPP1 1 0.06 0.34 0.17
200 INT185815 Binding of MMP1 and SPP1 1 0.21 0.34 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for membrane-bounded vesicle. They are ordered first by their pain relevance and then by number of times they were reported in membrane-bounded vesicle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
5 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
6 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
7 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
8 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31
9 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
10 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
11 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
12 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
13 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35
14 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81
15 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9
16 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26
17 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49
18 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
19 INT122902 Positive_regulation of Gene_expression of Spp1 54 0.70 56.3 6.33
20 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
21 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
22 INT88935 Positive_regulation of SPP1 36 0.70 31.07 5.49
23 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07
24 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
25 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
26 INT68260 Localization of BGLAP 34 0.78 16.04 4.63
27 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
28 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
29 INT97128 Localization of SPP1 32 0.80 21.75 4.02
30 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96
31 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
32 INT136791 Negative_regulation of Spp1 24 0.59 23.6 3.33
33 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
34 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
35 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
36 INT88130 Gene_expression of Spp1 13 0.74 12.96 3.07
37 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
38 INT91341 Negative_regulation of Gene_expression of BGLAP 17 0.55 4.91 3.02
39 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
40 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
41 INT91342 Negative_regulation of Negative_regulation of BGLAP 2 0.55 1.39 2.88
42 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
43 INT179791 Negative_regulation of Sparc 21 0.58 15.1 2.61
44 INT179788 Gene_expression of Sparc 42 0.77 19.96 2.57
45 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
46 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
47 INT176517 Negative_regulation of Gene_expression of Spp1 18 0.59 15.31 2.28
48 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
49 INT91340 Regulation of Localization of BGLAP 5 0.58 2.82 2.14
50 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
51 INT186893 Binding of BGLAP 10 0.37 6.19 2.02
52 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
53 INT176510 Binding of Spp1 21 0.42 22.1 2
54 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
55 INT176516 Localization of Spp1 28 0.76 19.39 1.9
56 INT89971 Localization of Sparc 10 0.80 10.25 1.85
57 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
58 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
59 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
60 INT133311 Binding of SPP1 10 0.37 9.47 1.65
61 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
62 INT97318 Gene_expression of SPARC 11 0.67 5.07 1.59
63 INT88136 Positive_regulation of Gene_expression of Spp1 8 0.66 4.5 1.57
64 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
65 INT88934 Regulation of SPP1 9 0.54 6.94 1.47
66 INT104250 Positive_regulation of Gene_expression of SPP1 17 0.69 13.22 1.44
67 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
68 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
69 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
70 INT88133 Positive_regulation of Spp1 8 0.66 10.07 1.33
71 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
72 INT52212 Gene_expression of Bmp6 6 0.64 2.38 1.27
73 INT119671 Gene_expression of IBSP 10 0.58 4.31 1.26
74 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
75 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
76 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
77 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
78 INT184547 Localization of Spp1 4 0.58 4.44 1.02
79 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
80 INT115987 Positive_regulation of SPARC 4 0.44 1.52 0.99
81 INT52213 Regulation of Localization of Bmp6 1 0.44 0.39 0.93
82 INT242988 Positive_regulation of Transcription of Spp1 4 0.28 3.28 0.92
83 INT114664 Binding of BMP2 12 0.37 6.54 0.91
84 INT52215 Localization of Bmp6 1 0.73 0.37 0.88
85 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
86 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83
87 INT89969 Positive_regulation of Sparc 7 0.67 4.14 0.82
88 INT294824 Positive_regulation of Gene_expression of Sparc 10 0.69 7.64 0.81
89 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
90 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79
91 INT176528 Regulation of Spp1 9 0.45 9.05 0.77
92 INT187418 Positive_regulation of Gene_expression of MTTP 5 0.18 4.83 0.76
93 INT312011 Negative_regulation of Binding of BGLAP 1 0.11 1.04 0.76
94 INT185838 Protein_catabolism of SPP1 1 0.65 1.68 0.74
95 INT150165 Gene_expression of MTTP 21 0.75 10.1 0.73
96 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72
97 INT12443 Regulation of Localization of Vegfa 2 0.20 0 0.72
98 INT176513 Transcription of Spp1 5 0.63 4.32 0.67
99 INT340625 Protein_catabolism of Vegfa 1 0.05 1.61 0.64
100 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
101 INT174868 Regulation of Negative_regulation of VEGFA 4 0.43 4.51 0.63
102 INT100294 Positive_regulation of Gene_expression of Bmp7 8 0.46 5.41 0.61
103 INT235398 Regulation of Gene_expression of BGLAP 3 0.27 1.03 0.61
104 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
105 INT88933 Regulation of Gene_expression of SPP1 7 0.45 6.05 0.59
106 INT242987 Positive_regulation of Localization of Spp1 3 0.60 7.04 0.59
107 INT127975 Negative_regulation of SPP1 15 0.42 11.25 0.56
108 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55
109 INT150807 Positive_regulation of Gene_expression of SPARC 1 0.43 0.53 0.55
110 INT172964 Binding of Vegfa 14 0.47 10.62 0.53
111 INT150806 Localization of SPARC 4 0.53 2.64 0.53
112 INT165537 Negative_regulation of Bmp7 2 0.43 0.55 0.52
113 INT133314 Positive_regulation of Binding of SPP1 2 0.22 2.38 0.52
114 INT105677 Binding of Vegfa 7 0.37 5.22 0.51
115 INT85808 Localization of BMP2 7 0.77 1.94 0.51
116 INT264716 Negative_regulation of Gene_expression of Sparc 6 0.43 3.16 0.51
117 INT145301 Regulation of Gene_expression of Bmp2 1 0.32 1.16 0.48
118 INT129620 Regulation of Gene_expression of Bmp7 3 0.42 3.2 0.47
119 INT263670 Binding of Bmp1 2 0.22 0.91 0.46
120 INT52214 Regulation of Gene_expression of Bmp6 1 0.37 0.19 0.46
121 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
122 INT224428 Positive_regulation of Localization of BGLAP 5 0.30 2.34 0.44
123 INT247568 Negative_regulation of Negative_regulation of VEGFA 5 0.41 5.35 0.43
124 INT120086 Gene_expression of Bmp2 5 0.27 2.34 0.43
125 INT268877 Regulation of Gene_expression of Vegfa 2 0.58 4.73 0.42
126 INT152023 Regulation of Vegfa 4 0.52 3.99 0.41
127 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
128 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
129 INT43720 Regulation of Positive_regulation of Vegfa 1 0.03 0.41 0.41
130 INT127976 Negative_regulation of Regulation of SPP1 1 0.37 1.62 0.41
131 INT43722 Positive_regulation of Regulation of Vegfa 1 0.06 0.41 0.41
132 INT118460 Binding of Bmp7 3 0.46 1.3 0.4
133 INT289704 Protein_catabolism of Spp1 5 0.27 2.42 0.39
134 INT129849 Positive_regulation of Localization of Vegfa 1 0.46 0.35 0.39
135 INT121141 Transcription of Spp1 6 0.34 5.02 0.38
136 INT180595 Regulation of IBSP 2 0.09 1.29 0.38
137 INT123185 Positive_regulation of Gene_expression of Bmp6 2 0.24 1.28 0.38
138 INT57118 Transcription of BGLAP 4 0.56 1.65 0.37
139 INT84945 Transcription of BMP2 5 0.61 1.8 0.36
140 INT196026 Positive_regulation of Gene_expression of Bmp2 14 0.69 3.19 0.35
141 INT176519 Regulation of Gene_expression of Spp1 7 0.58 8.54 0.35
142 INT329301 Phosphorylation of Spp1 1 0.62 1.71 0.34
143 INT185830 Positive_regulation of Localization of SPP1 2 0.50 3.39 0.33
144 INT179802 Regulation of Sparc 4 0.41 0.57 0.32
145 INT88134 Negative_regulation of Gene_expression of Spp1 2 0.41 1.94 0.32
146 INT196032 Positive_regulation of Gene_expression of Bmp7 10 0.17 1.31 0.31
147 INT280944 Gene_expression of Bmp1 1 0.22 0.91 0.31
148 INT196024 Gene_expression of Bmp7 20 0.26 1.88 0.3
149 INT176518 Positive_regulation of Positive_regulation of Spp1 5 0.47 3.36 0.28
150 INT224619 Regulation of Positive_regulation of Vegfa 1 0.05 0.57 0.27
151 INT224638 Positive_regulation of Positive_regulation of Vegfa 1 0.06 0.57 0.27
152 INT148796 Regulation of Phosphorylation of VEGFA 3 0.35 1.66 0.26
153 INT109537 Transcription of Vegfa 2 0.44 1.32 0.26
154 INT185828 Phosphorylation of SPP1 1 0.62 1.36 0.26
155 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24
156 INT145305 Positive_regulation of Bmp2 12 0.69 8.65 0.24
157 INT248262 Negative_regulation of Positive_regulation of Spp1 1 0.04 0.65 0.24
158 INT137608 Regulation of Localization of Vegfa 1 0.25 0.56 0.24
159 INT109699 Regulation of BMP2 5 0.43 2.21 0.23
160 INT97129 Transcription of SPP1 4 0.51 0.67 0.23
161 INT185826 Negative_regulation of Gene_expression of SPP1 1 0.42 0.8 0.23
162 INT88131 Negative_regulation of Spp1 3 0.56 0.7 0.21
163 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
164 INT180584 Positive_regulation of IBSP 1 0.16 0.37 0.21
165 INT340249 Positive_regulation of Positive_regulation of BGLAP 1 0.04 0.95 0.21
166 INT206159 Negative_regulation of Regulation of VEGFA 3 0.24 2.38 0.2
167 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
168 INT176522 Negative_regulation of Localization of Spp1 3 0.37 2.65 0.17
169 INT148064 Localization of Bmp2 2 0.29 0.14 0.17
170 INT180586 Transcription of IBSP 1 0.16 0.27 0.17
171 INT316803 Negative_regulation of Negative_regulation of Sparc 2 0.43 1.13 0.16
172 INT118459 Regulation of Bmp7 3 0.43 0.25 0.15
173 INT106010 Positive_regulation of Bmp2 2 0.26 0.91 0.15
174 INT201968 Positive_regulation of Bmp7 2 0.43 1.11 0.14
175 INT302444 Negative_regulation of Binding of Vegfa 2 0.57 4.08 0.12
176 INT246872 Negative_regulation of Localization of Vegfa 2 0.41 2.16 0.12
177 INT260740 Negative_regulation of Localization of Vegfa 1 0.10 0.19 0.12
178 INT254992 Negative_regulation of Gene_expression of BMP2 3 0.34 0.56 0.11
179 INT238044 Positive_regulation of Transcription of BMP2 2 0.43 0.83 0.11
180 INT88936 Positive_regulation of Regulation of SPP1 1 0.40 1.1 0.11
181 INT316809 Phosphorylation of Sparc 1 0.63 0.49 0.1
182 INT326976 Regulation of Localization of BMP2 1 0.59 0.08 0.1
183 INT184511 Positive_regulation of Negative_regulation of VEGFA 5 0.46 2.86 0.09
184 INT179820 Binding of Sparc 5 0.37 2.07 0.09
185 INT196035 Localization of Bmp2 3 0.63 0.23 0.09
186 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
187 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09
188 INT57117 Negative_regulation of Transcription of BGLAP 1 0.35 0.83 0.09
189 INT114663 Regulation of Binding of BMP2 1 0.38 0.19 0.09
190 INT248596 Regulation of Binding of BGLAP 1 0.27 0.39 0.09
191 INT207433 Positive_regulation of MTTP 5 0.14 2.47 0.08
192 INT163072 Regulation of Binding of Bmp2 1 0.30 0.52 0.08
193 INT144708 Regulation of Gene_expression of Spp1 1 0.04 0.32 0.08
194 INT355332 Localization of Bmp7 1 0.09 1.92 0.08
195 INT184552 Regulation of Spp1 1 0.17 1.55 0.08
196 INT247569 Positive_regulation of Regulation of VEGFA 6 0.48 4.15 0.07
197 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
198 INT175644 Positive_regulation of Gene_expression of IBSP 6 0.23 3.95 0.06
199 INT207722 Localization of IBSP 4 0.22 2.19 0.06
200 INT320271 Positive_regulation of Localization of IBSP 1 0.02 1.06 0.06
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