GO:0031994

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Name insulin-like growth factor I binding
Categary Function
Go Slim No
Go Link GO:0031994
Unique Molecular Interactions 157
Total Molecular Interactions 248
Total Single Events 2781
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for insulin-like growth factor I binding. They are ordered first by their pain relevance and then by number of times they were reported for insulin-like growth factor I binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
2 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
3 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
4 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
5 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
6 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
7 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
8 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
9 INT64127 Igfbp2 Regulation of Localization of Avp 1 0.39 0.19 0.9
10 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
11 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
12 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
13 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
14 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
15 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
16 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
17 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
18 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
19 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
20 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
21 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
22 INT114070 Agtr2 Positive_regulation of Gene_expression of Insr 1 0.13 0.34 0.52
23 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
24 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
25 INT133002 Mmp9 Regulation of Negative_regulation of Igfbp3 1 0.26 0.39 0.42
26 INT285725 Binding of IGF1R and INS 1 0.27 0.07 0.4
27 INT114067 Ace Regulation of Insr 1 0.09 0.31 0.39
28 INT336573 Ptpn2 Regulation of INSR 1 0.00 1.36 0.36
29 INT242403 INSR Positive_regulation of Gene_expression of Bdkrb1 1 0.45 0.88 0.35
30 INT277656 Igf1 Positive_regulation of Igfbp3 1 0.01 0.4 0.34
31 INT41406 Binding of Insr and Thtpa 1 0.05 0 0.25
32 INT92581 IGF1R Positive_regulation of Gene_expression of PTGER2 1 0.09 0.79 0.24
33 INT87750 IGFBP3 Negative_regulation of INS 1 0.11 0.86 0.23
34 INT89158 Grpr Positive_regulation of Localization of Insr 1 0.02 0 0.23
35 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18
36 INT185516 Binding of Igfbp2 and Csf2 1 0.14 0.29 0.17
37 INT269758 Negative_regulation of IGF1 Negative_regulation of Positive_regulation of IGFBP2 1 0.10 2.15 0.16
38 INT168941 Irs2 Regulation of Gene_expression of Igf1r 1 0.39 0.91 0.16
39 INT334634 Binding of Igf1 and Igf1r 1 0.14 0.45 0.15
40 INT92582 IGF1R Positive_regulation of Transcription of PTGER2 1 0.09 0.43 0.15
41 INT215902 Igfbp2 Positive_regulation of Igfals 1 0.15 0.8 0.15
42 INT220147 IGFBP3 Positive_regulation of IGF1 1 0.10 0.53 0.13
43 INT312218 INPP5K Positive_regulation of Protein_catabolism of IGFBP3 1 0.17 0.39 0.11
44 INT258147 IGFBP3 Negative_regulation of Hcrt 1 0.28 1.87 0.11
45 INT234626 IGFBP3 Regulation of IGF2 1 0.15 1.31 0.1
46 INT78446 Binding of GH1 and IGFBP3 1 0.11 0.48 0.1
47 INT349660 Binding of INSR and PYCARD 1 0.01 0 0.09
48 INT354120 Binding of IGF2 and IGFBP5 1 0.01 0.45 0.09
49 INT354124 Binding of IGF2 and IGFBP3 1 0.01 0.45 0.09
50 INT165157 Gli1 Regulation of Igfbp5 1 0.24 0.07 0.09
51 INT325059 Insr Positive_regulation of Ang 1 0.02 1.4 0.08
52 INT115258 Insr Positive_regulation of Phosphorylation of Irs1 1 0.19 0.26 0.08
53 INT124732 Gh Regulation of Positive_regulation of IGFBP3 1 0.00 0.24 0.08
54 INT268925 Igfbp2 Negative_regulation of Phosphorylation of Mapk14 1 0.01 0.35 0.08
55 INT49372 Gh Positive_regulation of Gene_expression of IGFBP3 1 0.00 0.51 0.08
56 INT312219 Binding of IGF1 and IGFBP5 1 0.02 0.13 0.08
57 INT354113 Binding of IGFBP3 and MIR524 1 0.01 0.69 0.07
58 INT354125 Binding of IGFBP3 and MIR15B 1 0.00 0.7 0.07
59 INT354111 Binding of IGFBP3 and MIR125A 1 0.11 0.7 0.07
60 INT51273 IGF1 Positive_regulation of IGFBP2 1 0.37 0.13 0.06
61 INT17920 Penk Positive_regulation of Insr 1 0.05 0.14 0.06
62 INT234619 IGF1 Regulation of IGF1R 1 0.11 0.39 0.05
63 INT234624 Binding of IGF1 and IGF1R 1 0.09 0.39 0.05
64 INT184123 Socs3 Positive_regulation of Protein_catabolism of Insr 1 0.03 0.41 0.05
65 INT234620 Regulation of Binding of IGF1 and IGF1R 1 0.07 0.39 0.05
66 INT325060 Binding of Insr and Hand1 1 0.00 0.16 0.05
67 INT312226 INPP5K Positive_regulation of IGFBP5 1 0.12 0.07 0.05
68 INT218616 Binding of IGFBP3 and INS 1 0.07 0.68 0.05
69 INT184085 Socs1 Positive_regulation of Protein_catabolism of Insr 1 0.04 0.41 0.05
70 INT275758 Binding of xn and Igfbp3 1 0.03 5.39 0.04
71 INT258148 Gene_expression of IGFBP3 Negative_regulation of Hcrt 1 0.28 0.86 0.04
72 INT342170 Insr Regulation of Localization of Cd320 1 0.08 0.92 0.04
73 INT275754 Regulation of Binding of xn and Igfbp3 1 0.02 0.79 0.04
74 INT225800 Binding of Insr and Enpp1 1 0.05 0.67 0.04
75 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03
76 INT258144 IGFBP3 Regulation of Gene_expression of Hcrt 1 0.30 2.23 0.03
77 INT144761 Binding of INSR and Insr 1 0.05 0 0
78 INT275760 Binding of Igfbp3 and xn 1 0.00 1.32 0
79 INT289672 Binding of GNRH1 and INSR 1 0.02 0 0
80 INT234622 IGFBP3 Positive_regulation of TNFSF10 1 0.56 1.08 0
81 INT258150 IGFBP3 Regulation of Gene_expression of Gopc 1 0.05 1.22 0
82 INT235623 Binding of INS and INSR 1 0.14 0.47 0
83 INT258146 Binding of IGFBP3 and Hcrt 1 0.23 2.04 0
84 INT278495 IGFBP2 Positive_regulation of Gene_expression of IGF1 1 0.20 0 0
85 INT144754 Negative_regulation of Binding of Insr and Slc2a2 1 0.01 0 0
86 INT275733 Igfbp3 Regulation of Ins1 1 0.03 0.16 0
87 INT277315 Binding of Insr and Mbnl1 1 0.18 1.1 0
88 INT278498 IGFBP3 Regulation of GH1 1 0.06 0 0
89 INT234621 CDX2 Negative_regulation of IGFBP3 1 0.38 0.8 0
90 INT114712 SRC Positive_regulation of Gene_expression of IGF1R 1 0.63 0.51 0
91 INT315065 IGF1R Regulation of Gene_expression of PAR4 1 0.37 0.53 0
92 INT258086 Binding of CSF2 and IGFBP3 1 0.05 1.18 0
93 INT258145 IGFBP3 Regulation of Hcrt 1 0.16 0.56 0
94 INT315049 IGF1R Regulation of MT1X 1 0.29 0.52 0
95 INT235624 INS Regulation of Phosphorylation of INSR 1 0.08 0.26 0
96 INT271281 Gene_expression of Stat1 Positive_regulation of Insr 1 0.19 0.51 0
97 INT215209 Binding of Igf1 and Igfbp3 1 0.11 0 0
98 INT271287 Gene_expression of IFNA1 Positive_regulation of Insr 1 0.03 0.51 0
99 INT308664 Akt1 Positive_regulation of Phosphorylation of Insr 1 0.02 0.43 0
100 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
101 INT319320 Binding of EGI and IGF1R 1 0.02 0.85 0
102 INT258152 IGFBP3 Regulation of Transcription of Hcrt 1 0.40 0.42 0
103 INT215205 Binding of Igf2 and Igfbp3 1 0.04 0 0
104 INT258087 Negative_regulation of ANTXR2 Negative_regulation of Gene_expression of IGFBP3 1 0.04 0.29 0
105 INT141959 Binding of IGFBP3 and Igf2 1 0.01 0.09 0
106 INT234623 Binding of CDX2 and IGFBP3 1 0.32 1.71 0
107 INT258151 IGFBP3 Negative_regulation of Binding of Hcrt 1 0.28 0.49 0
108 INT114713 Binding of IGF1R and SRC 1 0.33 0.6 0
109 INT132069 Binding of Igf1 and Igfbp3 1 0.38 0.08 0
110 INT180858 TGFB1 Regulation of Transcription of IGFBP3 1 0.24 0.77 0
111 INT218307 Grb10 Positive_regulation of Protein_catabolism of INSR 1 0.03 0 0
112 INT144753 Binding of Insr and Slc2a2 1 0.01 0 0
113 INT332159 Gh Positive_regulation of Gene_expression of Igfbp3 1 0.07 1.11 0
114 INT311383 Mbnl1 Regulation of Insr 1 0.00 0.24 0
115 INT144762 Negative_regulation of Binding of INSR and Insr 1 0.06 0 0
116 INT311386 Celf1 Regulation of Insr 1 0.00 0.24 0
117 INT307584 Binding of EGFR and IGF1R 1 0.03 0.52 0
118 INT258149 IGFBP3 Negative_regulation of Gene_expression of Hcrt 1 0.38 1.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for insulin-like growth factor I binding. They are ordered first by their pain relevance and then by number of times they were reported in insulin-like growth factor I binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
2 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
3 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
4 INT8691 Localization of Insr 85 0.80 9.27 30.32
5 INT5300 Regulation of Insr 54 0.60 11.33 29.26
6 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
7 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
8 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19
9 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
10 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
11 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
12 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
13 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
14 INT9325 Gene_expression of Igf1r 14 0.77 8.74 5.48
15 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
16 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
17 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
18 INT49130 Positive_regulation of IGFBP3 49 0.63 27.55 4.78
19 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
20 INT51084 Binding of Insr 13 0.30 4.25 4.23
21 INT83035 Binding of INSR 16 0.47 9.29 4.11
22 INT10116 Localization of INSR 11 0.57 5.43 3.48
23 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
24 INT124736 Positive_regulation of Gene_expression of Insr 6 0.31 7.55 3.12
25 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
26 INT51279 Regulation of IGFBP3 17 0.49 15.89 2.45
27 INT147417 Positive_regulation of Gene_expression of Igf1r 3 0.46 1.69 2.2
28 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
29 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
30 INT64125 Positive_regulation of Localization of Igfbp2 1 0.38 0.18 2.02
31 INT9336 Negative_regulation of Gene_expression of Igf1r 4 0.42 3.53 1.92
32 INT49371 Positive_regulation of Gene_expression of IGFBP3 27 0.70 23.13 1.9
33 INT114059 Localization of Insr 10 0.46 3.49 1.87
34 INT78938 Binding of IGFBP3 40 0.45 27.95 1.73
35 INT218303 Protein_catabolism of INSR 3 0.29 0.67 1.73
36 INT232645 Transcription of INSR 2 0.09 1.19 1.71
37 INT114061 Regulation of Gene_expression of Insr 4 0.27 2.03 1.56
38 INT19342 Regulation of Insr 12 0.24 6.11 1.54
39 INT61068 Gene_expression of Igfbp3 15 0.75 8.48 1.41
40 INT49128 Gene_expression of IGF1R 35 0.63 23.48 1.39
41 INT61066 Gene_expression of Igfbp2 55 0.77 2.01 1.35
42 INT124738 Negative_regulation of Positive_regulation of Insr 5 0.23 3.73 1.24
43 INT9323 Transcription of Igf1r 2 0.63 1.08 1.23
44 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22
45 INT48728 Negative_regulation of IGFBP3 28 0.59 14.84 1.21
46 INT9319 Localization of Igfbp2 6 0.80 1.13 1.17
47 INT106339 Positive_regulation of Phosphorylation of Insr 1 0.49 0 1.12
48 INT147416 Positive_regulation of Transcription of Igf1r 1 0.46 0.72 1.1
49 INT147415 Positive_regulation of Igf1r 2 0.43 0.97 1.09
50 INT32354 Negative_regulation of Regulation of Insr 3 0.33 0.13 1.08
51 INT171382 Phosphorylation of Insr 6 0.51 3.41 0.94
52 INT215202 Localization of Igfbp3 3 0.62 2.5 0.91
53 INT41911 Regulation of Positive_regulation of Insr 2 0.21 0.32 0.88
54 INT171376 Positive_regulation of Phosphorylation of Insr 3 0.31 3.05 0.86
55 INT91908 Regulation of Negative_regulation of Insr 1 0.03 0.81 0.86
56 INT132068 Gene_expression of Igfbp3 10 0.64 3.73 0.83
57 INT64126 Negative_regulation of Igfbp2 2 0.33 0.46 0.8
58 INT114714 Binding of IGF1R 8 0.36 5.26 0.78
59 INT144759 Regulation of Gene_expression of INSR 2 0.44 3.09 0.77
60 INT117849 Negative_regulation of Gene_expression of IGFBP3 8 0.39 8.75 0.75
61 INT277652 Negative_regulation of Localization of Igfbp3 1 0.11 0.74 0.72
62 INT49370 Localization of IGFBP3 21 0.81 9.85 0.71
63 INT117392 Binding of Insr 8 0.23 4.88 0.68
64 INT171366 Positive_regulation of Localization of Insr 3 0.18 0.63 0.66
65 INT18445 Regulation of Transcription of Insr 1 0.12 0.84 0.63
66 INT18446 Transcription of Insr 2 0.18 0.84 0.62
67 INT277647 Negative_regulation of Igfbp3 1 0.15 0.94 0.62
68 INT335991 Positive_regulation of Localization of Igfbp3 1 0.42 1.57 0.61
69 INT67341 Transcription of IGFBP3 27 0.72 30.46 0.57
70 INT145859 Regulation of Gene_expression of Igf1r 1 0.59 1.58 0.55
71 INT277649 Localization of Igfbp3 1 0.20 0.69 0.55
72 INT63364 Positive_regulation of Igfbp3 9 0.64 1.92 0.53
73 INT308979 Regulation of Localization of Insr 1 0.24 0.44 0.53
74 INT199342 Regulation of Igfbp2 5 0.60 3.3 0.5
75 INT132996 Positive_regulation of Gene_expression of Igfbp3 4 0.49 3.2 0.5
76 INT61067 Positive_regulation of Igfbp3 3 0.41 1.21 0.5
77 INT199332 Binding of Igfbp2 2 0.36 1.46 0.41
78 INT139668 Binding of Igfbp2 3 0.18 0.98 0.39
79 INT114062 Negative_regulation of Localization of Insr 1 0.19 0.31 0.39
80 INT124719 Regulation of Regulation of IGFBP3 3 0.36 2.02 0.38
81 INT294079 Protein_catabolism of IGFBP3 3 0.27 1.89 0.38
82 INT168940 Phosphorylation of Igf1r 1 0.77 2.18 0.38
83 INT132995 Negative_regulation of Igfbp3 1 0.44 0.36 0.38
84 INT144755 Negative_regulation of INSR 5 0.41 2.09 0.36
85 INT210766 Gene_expression of Igf1r 6 0.65 2.15 0.31
86 INT83030 Positive_regulation of Binding of INSR 2 0.49 2.35 0.31
87 INT61065 Positive_regulation of Igfbp2 9 0.69 1.13 0.3
88 INT277650 Negative_regulation of Transcription of Igfbp3 1 0.11 0.24 0.3
89 INT277654 Transcription of Igfbp3 1 0.18 0.24 0.3
90 INT9326 Regulation of Igfbp2 4 0.61 0.99 0.29
91 INT199343 Positive_regulation of Igfbp2 8 0.67 7.85 0.28
92 INT48727 Gene_expression of IGFBP2 7 0.46 1.94 0.28
93 INT278530 Regulation of Positive_regulation of Insr 1 0.01 1.96 0.28
94 INT145860 Negative_regulation of Gene_expression of Igfbp3 2 0.35 1.52 0.27
95 INT268924 Negative_regulation of Gene_expression of Igfbp2 1 0.02 0.8 0.27
96 INT124720 Regulation of Gene_expression of IGFBP3 2 0.39 3.1 0.26
97 INT132992 Negative_regulation of Gene_expression of Igfbp3 1 0.37 0.84 0.26
98 INT268478 Negative_regulation of Positive_regulation of Igfbp5 1 0.26 0.64 0.26
99 INT268477 Positive_regulation of Igfbp5 1 0.31 0.63 0.25
100 INT124735 Positive_regulation of Positive_regulation of Insr 1 0.08 0 0.25
101 INT115253 Negative_regulation of Phosphorylation of Insr 1 0.27 0.56 0.25
102 INT258095 Binding of Igfbp3 4 0.29 2.86 0.23
103 INT199333 Gene_expression of Igfbp2 8 0.65 9.3 0.21
104 INT192958 Negative_regulation of IGF1R 8 0.30 6.35 0.21
105 INT250517 Phosphorylation of Igf1r 5 0.79 1.21 0.21
106 INT213792 Positive_regulation of Igf1r 3 0.45 1 0.2
107 INT132067 Binding of Igfbp3 7 0.33 2.51 0.19
108 INT168938 Negative_regulation of Phosphorylation of Igf1r 1 0.40 1.1 0.19
109 INT215200 Regulation of Igfbp3 3 0.35 0.71 0.18
110 INT312242 Binding of IGFBP5 2 0.08 0.69 0.18
111 INT165152 Gene_expression of Igfbp5 1 0.70 0.13 0.18
112 INT275741 Positive_regulation of Gene_expression of Igfbp3 2 0.25 1.3 0.17
113 INT9322 Transcription of Igfbp2 2 0.44 0.44 0.17
114 INT171022 Binding of IGFBP2 1 0.19 0.62 0.16
115 INT51278 Positive_regulation of IGFBP2 2 0.32 1.17 0.15
116 INT168939 Negative_regulation of Igf1r 1 0.40 1.01 0.15
117 INT294084 Regulation of Negative_regulation of IGFBP3 1 0.08 0.81 0.14
118 INT9320 Regulation of Transcription of Igf1r 1 0.04 0.36 0.13
119 INT9333 Regulation of Igf1r 1 0.07 0.36 0.13
120 INT285623 Regulation of Binding of Igfbp2 1 0.34 0.56 0.13
121 INT285629 Regulation of Binding of Igfbp3 1 0.35 0.56 0.13
122 INT268476 Protein_catabolism of Igfbp5 1 0.40 0.25 0.13
123 INT92590 Positive_regulation of Gene_expression of IGF1R 3 0.57 2.31 0.12
124 INT92634 Negative_regulation of Binding of Insr 1 0.25 0.08 0.12
125 INT92589 Positive_regulation of IGF1R 4 0.38 0.98 0.11
126 INT308981 Positive_regulation of Negative_regulation of Insr 1 0.27 0.95 0.11
127 INT323945 Positive_regulation of Binding of Insr 1 0.08 0.94 0.11
128 INT312954 Regulation of Binding of IGF1R 1 0.13 0 0.1
129 INT250519 Negative_regulation of Igf1r 5 0.42 2.7 0.09
130 INT75111 Negative_regulation of Positive_regulation of IGFBP3 2 0.40 3.44 0.09
131 INT199348 Negative_regulation of Igfbp2 1 0.41 0.2 0.09
132 INT165155 Regulation of Igfbp5 1 0.55 0.07 0.09
133 INT92587 Positive_regulation of Positive_regulation of IGF1R 1 0.38 0.38 0.08
134 INT312250 Protein_catabolism of IGFBP5 1 0.22 0.24 0.08
135 INT349623 Negative_regulation of Binding of Igf1r 1 0.39 0.51 0.08
136 INT250508 Negative_regulation of Gene_expression of Igf1r 1 0.42 2.01 0.08
137 INT349620 Binding of Igf1r 1 0.34 0.51 0.08
138 INT124721 Regulation of Localization of IGFBP3 1 0.10 0.23 0.07
139 INT234462 Phosphorylation of IGF1R 2 0.42 0.99 0.06
140 INT234630 Negative_regulation of Transcription of IGFBP3 1 0.43 2.1 0.06
141 INT132066 Regulation of Igfbp3 1 0.56 0.09 0.06
142 INT67340 Localization of IGFBP5 1 0.55 0.17 0.06
143 INT67338 Localization of IGFBP2 1 0.54 0.17 0.06
144 INT234629 Regulation of Transcription of IGFBP3 3 0.40 3.29 0.05
145 INT275737 Positive_regulation of Binding of Igfbp3 1 0.18 0 0.05
146 INT315099 Localization of IGF1R 2 0.55 0.36 0.04
147 INT231433 Positive_regulation of Binding of IGFBP3 2 0.34 0.6 0.04
148 INT269760 Positive_regulation of Gene_expression of IGFBP2 1 0.23 0.54 0.04
149 INT184013 Protein_catabolism of Insr 1 0.05 0.4 0.04
150 INT312249 Gene_expression of IGFBP5 1 0.18 0.07 0.04
151 INT234471 Negative_regulation of Phosphorylation of IGF1R 1 0.04 0.76 0.03
152 INT117362 Positive_regulation of Positive_regulation of INSR 1 0.22 0.1 0.03
153 INT278502 Positive_regulation of Positive_regulation of IGFBP3 1 0.26 0.4 0.03
154 INT210311 Regulation of Gene_expression of Igfbp2 1 0.61 0 0.03
155 INT334692 Localization of Igf1r 1 0.09 0.89 0.03
156 INT235634 Phosphorylation of INSR 24 0.70 3.64 0
157 INT222308 Regulation of IGF1R 3 0.12 2.18 0
158 INT339214 Negative_regulation of Gene_expression of IGF1R 2 0.22 0.4 0
159 INT282728 Regulation of Igf1r 2 0.18 0.92 0
160 INT215947 Positive_regulation of Gene_expression of INSR 2 0.14 0.25 0
161 INT180890 Positive_regulation of Transcription of IGFBP3 2 0.47 2.18 0
162 INT199356 Positive_regulation of Gene_expression of Igfbp2 1 0.48 2.86 0
163 INT321694 Positive_regulation of Phosphorylation of Igf1r 1 0.27 0.2 0
164 INT338259 Positive_regulation of Binding of IGF1R 1 0.27 1.38 0
165 INT210310 Positive_regulation of Gene_expression of Igfbp2 1 0.69 0.07 0
166 INT199344 Negative_regulation of Positive_regulation of Igfbp2 1 0.41 0.87 0
167 INT210309 Regulation of Positive_regulation of Igfbp2 1 0.45 0 0
168 INT144758 Negative_regulation of Negative_regulation of INSR 1 0.41 0 0
169 INT319333 Transcription of IGF1R 1 0.31 0.85 0
170 INT321704 Positive_regulation of Positive_regulation of Igf1r 1 0.18 0.17 0
171 INT307056 Positive_regulation of Localization of IGFBP3 1 0.39 0.99 0
172 INT235628 Negative_regulation of Phosphorylation of INSR 1 0.16 0.25 0
173 INT230481 Positive_regulation of Regulation of Insr 1 0.01 0.24 0
174 INT144756 Positive_regulation of Negative_regulation of INSR 1 0.49 0 0
175 INT144757 Negative_regulation of Gene_expression of INSR 1 0.41 0 0
176 INT67335 Transcription of IGFBP5 1 0.37 0 0
177 INT275743 Negative_regulation of Binding of Igfbp3 1 0.16 0.2 0
178 INT67343 Transcription of IGFBP2 1 0.36 0 0
179 INT307062 Negative_regulation of Localization of IGFBP3 1 0.24 0.05 0
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