GO:0032008

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Name positive regulation of TOR signaling cascade
Categary Process
Go Slim No
Go Link GO:0032008
Unique Molecular Interactions 96
Total Molecular Interactions 150
Total Single Events 697
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of TOR signaling cascade. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of TOR signaling cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
2 INT299311 Binding of RPTOR and RICTOR 1 0.38 0.21 1.4
3 INT299281 Binding of RPTOR and MAPKAP1 1 0.23 0.21 1.3
4 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
5 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
6 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
7 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 1 0.07 0.48 0.67
8 INT45335 Mlst8 Positive_regulation of Localization of Abat 1 0.36 0 0.65
9 INT45334 Mlst8 Regulation of Localization of Abat 1 0.21 0 0.65
10 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52
11 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52
12 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
13 INT117184 GOLPH3 Regulation of CXCR4 1 0.30 0.29 0.37
14 INT117182 GOLPH3 Regulation of Binding of CXCR4 1 0.50 0.29 0.37
15 INT299288 AKT1 Positive_regulation of RPTOR 1 0.34 0.05 0.36
16 INT337156 Kdr Positive_regulation of Gtf3a 1 0.01 0.77 0.35
17 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
18 INT337162 Binding of Kdr and Iqgap1 1 0.32 0.98 0.28
19 INT75989 Regulation of RICTOR Positive_regulation of IK 1 0.00 0.15 0.27
20 INT75988 RICTOR Positive_regulation of IK 1 0.00 0.15 0.27
21 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23
22 INT149791 Binding of Lrp8 and Reln 4 0.36 0.38 0.22
23 INT117183 Binding of CXCR4 and GOLPH3 1 0.53 0.27 0.16
24 INT123180 Bmp6 Positive_regulation of Lamtor1 1 0.01 0.61 0.14
25 INT230761 VEGFA Positive_regulation of Kdr 2 0.02 2.16 0.12
26 INT299310 RPTOR Positive_regulation of AKT1 1 0.30 0 0.12
27 INT101231 Positive_regulation of Gria2 Positive_regulation of Binding of Mlst8 1 0.06 0 0.12
28 INT337155 Binding of Kdr and Ros1 1 0.06 0.46 0.12
29 INT337159 Binding of ecs and Kdr 1 0.04 0.46 0.12
30 INT149792 Binding of Reln and Vldlr 3 0.51 0.35 0.11
31 INT341004 Reln Positive_regulation of Fabp7 1 0.03 0.12 0.08
32 INT320785 Binding of Flt1 and Kdr 1 0.15 0.67 0.08
33 INT302139 LAMTOR1 Regulation of CDKN2A 1 0.08 0.26 0.08
34 INT302160 LAMTOR1 Regulation of CDKN1A 1 0.08 0.26 0.06
35 INT292811 Zfp787 Negative_regulation of Phosphorylation of Kdr 1 0.01 0.45 0.06
36 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06
37 INT298699 Kdr Regulation of Tek 1 0.11 0.28 0.06
38 INT345371 Binding of Flt4 and Kdr 1 0.10 1.12 0.05
39 INT341019 Binding of VLDLR and Reln 1 0.01 0.1 0.05
40 INT299302 Negative_regulation of RPTOR Regulation of AKT1 1 0.30 0.1 0.05
41 INT299304 RPTOR Regulation of AKT1 1 0.19 0.1 0.05
42 INT341011 Reln Positive_regulation of Cp 1 0.00 0.15 0.04
43 INT198917 Lrp8 Negative_regulation of Binding of Reln 1 0.15 0 0.04
44 INT341002 Reln Positive_regulation of Gene_expression of Fabp7 1 0.04 0.32 0.04
45 INT320786 Binding of Eng and Kdr 1 0.04 1.17 0.04
46 INT341016 Reln Positive_regulation of Positive_regulation of PIK3CB 1 0.01 0.15 0.04
47 INT149793 Binding of LRP8 and Reln 1 0.03 0.17 0.04
48 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03
49 INT343476 Epo Positive_regulation of Kdr 1 0.11 0.31 0.03
50 INT343474 Epo Positive_regulation of Gene_expression of Kdr 1 0.11 0.32 0.03
51 INT341003 Reln Positive_regulation of Positive_regulation of Lrp8 1 0.03 0.11 0
52 INT312330 Binding of Kdr and Flt1 1 0.12 0.37 0
53 INT215698 Lamtor1 Negative_regulation of Kras 1 0.00 0 0
54 INT265562 Gla Positive_regulation of Gene_expression of Kdr 1 0.05 0.51 0
55 INT300447 Kdr Regulation of VEGFA 1 0.07 0.25 0
56 INT296960 Binding of NRIP1 and MLST8 1 0.03 2.65 0
57 INT341006 Reln Regulation of Gene_expression of Fabp7 1 0.03 0 0
58 INT345375 VEGFA Positive_regulation of Gene_expression of Kdr 1 0.02 1.2 0
59 INT215706 Binding of Cdk6 and Lamtor1 1 0.04 0 0
60 INT299292 RPTOR Negative_regulation of PI3 1 0.25 0 0
61 INT299296 SRC Regulation of RPTOR 1 0.32 0 0
62 INT299306 Binding of QPCT and RICTOR 1 0.02 0 0
63 INT302364 Binding of Arx and Reln 1 0.32 1.25 0
64 INT324662 Negative_regulation of Kdr Positive_regulation of Vash1 1 0.51 0.55 0
65 INT265563 Gla Positive_regulation of Transcription of Kdr 1 0.04 0.51 0
66 INT215697 Lamtor1 Negative_regulation of Cdkn1b 1 0.02 0 0
67 INT300437 Kdr Regulation of Gene_expression of Flt1 1 0.42 0.26 0
68 INT300443 VEGFA Positive_regulation of Phosphorylation of Kdr 1 0.08 0.64 0
69 INT296955 Binding of CIDEA and MLST8 1 0.02 0.97 0
70 INT299284 RICTOR Negative_regulation of PI3 1 0.18 0 0
71 INT298702 Tek Regulation of Kdr 1 0.03 0.33 0
72 INT300438 Efna1 Negative_regulation of Phosphorylation of Kdr 1 0.42 0.66 0
73 INT300436 Flt1 Negative_regulation of Kdr 1 0.35 0.4 0
74 INT299280 VEGFA Positive_regulation of RPTOR 1 0.29 0 0
75 INT353125 Negative_regulation of Binding of VEGFA and Kdr 1 0.04 5.92 0
76 INT302634 Rac1 Regulation of Gene_expression of Kdr 1 0.36 0 0
77 INT299283 Binding of VEGFA and RPTOR 1 0.19 0 0
78 INT205614 Gm6668 Negative_regulation of Kdr 1 0.01 1.5 0
79 INT296958 NRIP1 Regulation of Gene_expression of MLST8 1 0.04 0.76 0
80 INT341001 Binding of Reln and Vim 1 0.02 0.14 0
81 INT299290 Binding of VEGFA and RICTOR 1 0.16 0 0
82 INT345372 Col18a1 Positive_regulation of Kdr 1 0.20 1.42 0
83 INT215695 Lamtor1 Negative_regulation of Cdkn1c 1 0.02 0 0
84 INT299293 Binding of QPCT and RPTOR 1 0.02 0 0
85 INT341024 VLDLR Positive_regulation of Reln 1 0.02 0 0
86 INT213745 Binding of Kdr and Epc1 1 0.17 0 0
87 INT298700 Kdr Regulation of Manea 1 0.01 0.33 0
88 INT331701 Fgf4 Positive_regulation of Gene_expression of Kdr 1 0.11 0.54 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of TOR signaling cascade. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of TOR signaling cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09
2 INT213741 Gene_expression of Kdr 60 0.75 44.24 5.35
3 INT96748 Gene_expression of GOLPH3 7 0.58 5.13 4.42
4 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33
5 INT299340 Negative_regulation of RPTOR 1 0.53 1.68 2.6
6 INT134626 Positive_regulation of Gene_expression of Kdr 20 0.63 14.63 2.29
7 INT12965 Negative_regulation of RICTOR 3 0.37 0.32 2
8 INT265064 Binding of Reln 1 0.02 2.7 1.83
9 INT162725 Binding of Kdr 13 0.42 8.86 1.79
10 INT265066 Positive_regulation of Reln 1 0.02 1.59 1.72
11 INT28735 Localization of Reln 2 0.12 1.49 1.7
12 INT299331 Positive_regulation of RPTOR 1 0.63 0.9 1.62
13 INT2498 Positive_regulation of Mlst8 2 0.47 0.73 1.56
14 INT26579 Regulation of RICTOR 2 0.23 0.09 1.51
15 INT163523 Regulation of GOLPH3 2 0.08 1.57 1.41
16 INT159312 Regulation of Reln 4 0.43 1.79 1.4
17 INT199567 Binding of Kdr 18 0.47 13.81 1.34
18 INT299333 Gene_expression of RPTOR 1 0.61 0.25 1.18
19 INT104872 Positive_regulation of GOLPH3 3 0.18 1.34 1.15
20 INT123643 Gene_expression of Reln 19 0.75 1.85 1.13
21 INT299342 Regulation of RPTOR 1 0.41 1.06 1.1
22 INT200556 Regulation of Kdr 8 0.28 6.04 1.01
23 INT260471 Positive_regulation of Gene_expression of Kdr 9 0.61 8.37 0.99
24 INT140720 Negative_regulation of Reln 5 0.57 2.43 0.95
25 INT99287 Binding of GOLPH3 6 0.35 2.87 0.85
26 INT299350 Phosphorylation of RPTOR 1 0.75 0.26 0.82
27 INT297469 Regulation of Binding of Kdr 1 0.54 2.01 0.8
28 INT200855 Positive_regulation of Kdr 14 0.45 11.14 0.77
29 INT296992 Gene_expression of MLST8 19 0.07 18.39 0.73
30 INT60503 Positive_regulation of RICTOR 4 0.36 0.14 0.71
31 INT127684 Negative_regulation of Kdr 6 0.37 3.19 0.7
32 INT178489 Negative_regulation of Kdr 31 0.42 25.65 0.66
33 INT149788 Binding of Reln 4 0.37 1.41 0.6
34 INT312653 Negative_regulation of GOLPH3 1 0.06 1.08 0.59
35 INT312652 Protein_catabolism of GOLPH3 1 0.09 0.9 0.56
36 INT45333 Localization of Mlst8 1 0.63 0 0.52
37 INT45338 Gene_expression of RICTOR 4 0.52 0.89 0.48
38 INT45845 Negative_regulation of Gene_expression of Mlst8 1 0.43 0 0.44
39 INT45331 Regulation of Mlst8 1 0.40 0 0.43
40 INT292795 Regulation of Kdr 5 0.40 3.86 0.42
41 INT126389 Binding of RICTOR 1 0.01 0.08 0.38
42 INT126390 Positive_regulation of Binding of RICTOR 1 0.01 0.08 0.38
43 INT288109 Localization of Kdr 4 0.46 2.84 0.33
44 INT37205 Localization of LAMTOR1 1 0.02 0 0.31
45 INT149790 Localization of Reln 2 0.79 1.38 0.29
46 INT298809 Localization of MLST8 2 0.07 2.17 0.26
47 INT291184 Regulation of Gene_expression of Kdr 3 0.54 4.81 0.25
48 INT125027 Positive_regulation of Kdr 15 0.50 7.73 0.24
49 INT45844 Gene_expression of Mlst8 2 0.67 0.09 0.22
50 INT236499 Negative_regulation of Gene_expression of GOLPH3 1 0.05 0.09 0.2
51 INT159314 Positive_regulation of Gene_expression of Reln 1 0.44 0.47 0.2
52 INT267833 Phosphorylation of MLST8 1 0.01 1.68 0.2
53 INT200555 Negative_regulation of Gene_expression of Kdr 8 0.38 3.78 0.19
54 INT203894 Localization of Lamtor3 1 0.10 0.65 0.19
55 INT296978 Negative_regulation of MLST8 3 0.04 5.26 0.18
56 INT244270 Localization of GOLPH3 2 0.68 0.29 0.17
57 INT244269 Regulation of Localization of GOLPH3 1 0.16 0.3 0.17
58 INT299349 Localization of RPTOR 1 0.68 0 0.16
59 INT343138 Gene_expression of Mlst8 1 0.03 0 0.15
60 INT297468 Transcription of Kdr 6 0.63 1.85 0.14
61 INT123184 Negative_regulation of Lamtor1 2 0.13 0.59 0.14
62 INT298811 Transcription of MLST8 1 0.06 0.77 0.14
63 INT123186 Positive_regulation of Negative_regulation of Lamtor1 1 0.03 0.6 0.14
64 INT298818 Negative_regulation of Transcription of MLST8 1 0.04 0.78 0.14
65 INT299315 Regulation of Gene_expression of RPTOR 1 0.41 0 0.14
66 INT296990 Positive_regulation of MLST8 2 0.05 2.89 0.13
67 INT296995 Regulation of MLST8 2 0.03 3.1 0.13
68 INT323422 Regulation of Regulation of Kdr 1 0.17 0.5 0.13
69 INT340963 Positive_regulation of Positive_regulation of Reln 1 0.08 0.75 0.13
70 INT292809 Phosphorylation of Kdr 3 0.72 1.99 0.12
71 INT292807 Negative_regulation of Phosphorylation of Kdr 3 0.37 1.56 0.12
72 INT155189 Regulation of Reln 2 0.44 0.94 0.12
73 INT101227 Positive_regulation of Binding of Mlst8 1 0.07 0 0.12
74 INT101228 Binding of Mlst8 1 0.07 0 0.12
75 INT340975 Positive_regulation of Reln 1 0.08 0.78 0.12
76 INT200557 Regulation of Gene_expression of Kdr 6 0.44 2.72 0.11
77 INT127803 Negative_regulation of Positive_regulation of LAMTOR1 1 0.24 0.94 0.1
78 INT127804 Positive_regulation of LAMTOR1 1 0.39 0.92 0.1
79 INT299328 Localization of RICTOR 1 0.57 0 0.09
80 INT265068 Transcription of Reln 1 0.03 0.07 0.09
81 INT298820 Negative_regulation of Positive_regulation of MLST8 1 0.03 0.68 0.08
82 INT299343 Negative_regulation of Gene_expression of RPTOR 1 0.39 0 0.08
83 INT123644 Negative_regulation of Gene_expression of Reln 2 0.41 0.95 0.07
84 INT123646 Transcription of Reln 1 0.52 0.66 0.07
85 INT200853 Negative_regulation of Binding of Kdr 2 0.11 0.93 0.06
86 INT179116 Localization of Kdr 1 0.58 4.65 0.06
87 INT299341 Positive_regulation of Phosphorylation of RPTOR 1 0.46 0.1 0.06
88 INT299322 Positive_regulation of Gene_expression of RICTOR 1 0.38 0 0.05
89 INT299321 Positive_regulation of Gene_expression of RPTOR 1 0.46 0 0.05
90 INT340952 Positive_regulation of Localization of Reln 1 0.09 0.24 0.04
91 INT339762 Gene_expression of LAMTOR1 1 0.09 0.67 0.04
92 INT339757 Positive_regulation of Gene_expression of LAMTOR1 1 0.07 0.74 0.04
93 INT296974 Regulation of Gene_expression of MLST8 1 0.03 1.11 0.03
94 INT255669 Regulation of Positive_regulation of Kdr 1 0.08 1.1 0.03
95 INT199552 Phosphorylation of Kdr 4 0.38 1.27 0
96 INT265544 Transcription of Kdr 4 0.50 3.14 0
97 INT291191 Negative_regulation of Gene_expression of Kdr 4 0.24 4.46 0
98 INT300429 Negative_regulation of Transcription of Kdr 2 0.38 0.49 0
99 INT324642 Positive_regulation of Protein_catabolism of Kdr 1 0.61 0.64 0
100 INT281251 Negative_regulation of LAMTOR1 1 0.12 1.42 0
101 INT302619 Regulation of Transcription of Kdr 1 0.32 0.47 0
102 INT353123 Negative_regulation of Negative_regulation of Kdr 1 0.05 0.78 0
103 INT240133 Phosphorylation of Lamtor3 1 0.01 0.1 0
104 INT223679 Protein_catabolism of RICTOR 1 0.02 0.92 0
105 INT281253 Negative_regulation of Negative_regulation of LAMTOR1 1 0.09 1.49 0
106 INT324652 Protein_catabolism of Kdr 1 0.87 0.64 0
107 INT300433 Positive_regulation of Phosphorylation of Kdr 1 0.61 1.1 0
108 INT179106 Positive_regulation of Localization of Kdr 1 0.33 0.44 0
109 INT296993 Positive_regulation of Gene_expression of MLST8 1 0.04 1.04 0
110 INT199564 Negative_regulation of Phosphorylation of Kdr 1 0.27 1.12 0
111 INT179113 Negative_regulation of Localization of Kdr 1 0.31 0.41 0
112 INT324653 Positive_regulation of Transcription of Kdr 1 0.41 0.64 0
113 INT296985 Binding of MLST8 1 0.02 1.31 0
114 INT225967 Regulation of Negative_regulation of Lamtor1 1 0.13 0 0
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