GO:0032092

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Name positive regulation of protein binding
Categary Process
Go Slim No
Go Link GO:0032092
Unique Molecular Interactions 525
Total Molecular Interactions 665
Total Single Events 4202
Pain Genes Associated 41

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein binding. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT87267 Binding of BMP8B and KRIT1 1 0.06 0.16 2.69
2 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
3 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
4 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
5 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
6 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
7 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
8 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
9 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38
10 INT50706 Phax Positive_regulation of Localization of Trib3 1 0.04 0.28 1.38
11 INT161185 NMS Regulation of Gene_expression of Trib3 1 0.03 2 1.38
12 INT87266 Negative_regulation of Binding of BMP8B and KRIT1 1 0.05 0.07 1.37
13 INT95406 Trib3 Positive_regulation of Ephb1 2 0.08 0.96 1.29
14 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
15 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
16 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
17 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
18 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
19 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14
20 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
21 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04
22 INT101443 Penk Positive_regulation of Localization of Gcg 1 0.50 1.21 1.04
23 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
24 INT97735 Trib3 Positive_regulation of Mapk3 1 0.05 0.66 0.87
25 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
26 INT261480 Negative_regulation of Trib3 Positive_regulation of Ephb1 1 0.04 0.8 0.84
27 INT186428 Trib3 Regulation of Prkcg 1 0.02 0.09 0.81
28 INT150680 Pomc Negative_regulation of Gene_expression of Eif2ak3 1 0.35 0.07 0.8
29 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
30 INT128041 Bdnf Positive_regulation of Trib3 1 0.10 0.29 0.79
31 INT50708 Phax Positive_regulation of Trib3 1 0.03 0.07 0.77
32 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 0.09 2.05 0.76
33 INT50707 Phax Positive_regulation of Positive_regulation of Trib3 1 0.04 0.16 0.74
34 INT31642 POMC Regulation of GCG 1 0.41 0.62 0.73
35 INT101676 Sst Negative_regulation of Localization of Gcg 1 0.03 0 0.72
36 INT87275 KRIT1 Regulation of Oprd1 1 0.01 0.08 0.72
37 INT101444 Penk Regulation of Localization of Gcg 1 0.45 0.77 0.71
38 INT161298 Ppp1r1b Negative_regulation of Trib3 1 0.05 0.16 0.7
39 INT282665 Binding of Gfap and Ticam1 1 0.01 0 0.69
40 INT82022 Binding of Trib3 and Ngf 1 0.08 0.31 0.68
41 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
42 INT82020 Negative_regulation of Binding of Trib3 and Ngf 1 0.07 0.31 0.68
43 INT134028 Olr696 Regulation of Trib3 1 0.00 0.15 0.68
44 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
45 INT112515 Binding of Ephb1 and Trib3 1 0.06 0.41 0.65
46 INT31418 Positive_regulation of Adra2c Positive_regulation of Gcg 1 0.22 0 0.65
47 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
48 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
49 INT30902 GCG Positive_regulation of Localization of SST 1 0.11 0.05 0.62
50 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
51 INT57246 Crh Positive_regulation of Positive_regulation of Caprin2 1 0.01 0.55 0.6
52 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58
53 INT118003 Trib3 Regulation of Trpv1 1 0.03 0.09 0.58
54 INT282142 Grm1 Positive_regulation of Positive_regulation of Trib3 1 0.01 0.27 0.57
55 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
56 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56
57 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
58 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
59 INT161250 Trib3 Regulation of Mapk14 1 0.04 0.81 0.54
60 INT149321 Amph Positive_regulation of Trib3 1 0.16 0 0.54
61 INT330545 Bcl2l11 Negative_regulation of Trib3 1 0.00 0.38 0.52
62 INT108467 GCG Positive_regulation of Cck 1 0.02 0.16 0.51
63 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
64 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
65 INT7849 Man2a2 Positive_regulation of Localization of Gcg 1 0.08 0 0.51
66 INT25524 Oprd1 Regulation of Localization of GCG 1 0.01 0.52 0.48
67 INT162993 Binding of Trib3 and Fadd 1 0.05 0.1 0.46
68 INT162990 Binding of Trib3 and Pea15a 1 0.04 0.09 0.46
69 INT106001 Binding of PLAUR and VTN 2 0.23 1.5 0.45
70 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
71 INT128043 Positive_regulation of Ntrk2 Positive_regulation of Phosphorylation of Trib3 1 0.07 0.34 0.45
72 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
73 INT283731 Trib3 Positive_regulation of Creb1 2 0.01 0.16 0.44
74 INT313377 Trib3 Regulation of Gene_expression of Gfap 1 0.01 0.37 0.44
75 INT313378 Trib3 Regulation of Phosphorylation of Mapk14 1 0.01 0.37 0.44
76 INT114599 Positive_regulation of Il1rap Positive_regulation of Trib3 1 0.03 0.07 0.43
77 INT95403 Ephb1 Regulation of Positive_regulation of Trib3 1 0.07 0.19 0.41
78 INT95402 Mapk14 Regulation of Positive_regulation of Trib3 1 0.06 0.19 0.41
79 INT241679 EIF2AK3 Positive_regulation of Atf4 1 0.06 0.46 0.4
80 INT114598 Positive_regulation of Il1b Positive_regulation of Trib3 1 0.08 0.08 0.4
81 INT114594 Il1b Positive_regulation of Positive_regulation of Trib3 1 0.08 0.08 0.4
82 INT114596 Il1b Positive_regulation of Trib3 1 0.08 0.08 0.4
83 INT114597 Positive_regulation of Trib3 Regulation of Gene_expression of Tac4 1 0.01 0.09 0.4
84 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
85 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
86 INT113551 Binding of ITGA3 and VTN 1 0.02 1.03 0.38
87 INT43956 GCG Regulation of ALB 1 0.16 0.15 0.38
88 INT113555 Negative_regulation of Binding of FN1 and VTN 1 0.23 0.87 0.37
89 INT113559 Binding of PLAU and VTN 1 0.28 0.82 0.37
90 INT113554 Negative_regulation of Binding of PLAU and VTN 1 0.32 0.87 0.37
91 INT140869 Binding of Gdnf and Trib3 1 0.04 0.15 0.37
92 INT113547 Negative_regulation of Binding of PLAUR and VTN 1 0.26 0.87 0.37
93 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
94 INT118000 Trpv1 Regulation of Phosphorylation of Trib3 1 0.01 0.08 0.36
95 INT117999 Trpv1 Positive_regulation of Phosphorylation of Trib3 1 0.02 0.08 0.36
96 INT224285 BDNF Positive_regulation of Trib3 1 0.06 0.22 0.36
97 INT122757 Helt Positive_regulation of Trib3 1 0.00 0.2 0.35
98 INT263383 Abl1 Regulation of Trib3 1 0.01 0.28 0.35
99 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
100 INT304495 Trib3 Positive_regulation of Mapk1 1 0.02 1.4 0.35
101 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
102 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33
103 INT88252 Binding of RAP1A and Krit1 1 0.36 2.25 0.33
104 INT20468 Ran Negative_regulation of Localization of Prl 1 0.30 0 0.33
105 INT309132 Edc4 Negative_regulation of Positive_regulation of Trib3 1 0.00 0.69 0.33
106 INT306323 Tlr4 Positive_regulation of Ticam1 3 0.25 0.55 0.3
107 INT356288 Egf Positive_regulation of Trib3 1 0.00 0.17 0.3
108 INT169612 OGFR Regulation of RAN 1 0.23 0.14 0.3
109 INT186430 Creb1 Positive_regulation of Trib3 1 0.04 0.17 0.3
110 INT356283 Ngf Positive_regulation of Trib3 1 0.00 0.17 0.3
111 INT356282 Gdnf Positive_regulation of Trib3 1 0.00 0.17 0.3
112 INT207823 SSTR2 Negative_regulation of Localization of GCG 1 0.06 0 0.29
113 INT26175 POMC Positive_regulation of GCG 2 0.47 0.57 0.28
114 INT174311 Binding of Krit1 and Rap1a 1 0.04 1.08 0.28
115 INT283733 Trib3 Positive_regulation of Creb1 1 0.00 0 0.28
116 INT246689 Zglp1 Positive_regulation of Ide 1 0.06 0.28 0.27
117 INT7850 Adra2c Regulation of Localization of Gcg 1 0.08 0 0.27
118 INT233784 Binding of GCG and SCT 1 0.06 0 0.27
119 INT238632 Binding of EPB41 and Cask 1 0.44 0.78 0.27
120 INT246693 Zglp1 Positive_regulation of Localization of Ide 1 0.08 0.34 0.27
121 INT37309 Ins1 Negative_regulation of Localization of Gcg 1 0.12 0 0.27
122 INT36292 GCG Positive_regulation of MIA3 1 0.01 1.06 0.26
123 INT53951 Negative_regulation of Trib3 Negative_regulation of Gene_expression of Ptgs1 1 0.01 0.43 0.26
124 INT149357 Trib3 Negative_regulation of Raf1 1 0.01 0.08 0.25
125 INT51432 Gria1 Positive_regulation of Trib3 1 0.04 0 0.25
126 INT246692 Zglp1 Regulation of Gene_expression of Ros1 1 0.04 0.38 0.24
127 INT177661 Binding of Trib3 and Myo1f 1 0.00 0.54 0.24
128 INT130691 CA2 Positive_regulation of EIF2AK3 1 0.16 0.59 0.24
129 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
130 INT115875 Col5a1 Positive_regulation of Localization of Gcg 1 0.08 0 0.23
131 INT260835 NRP2 Positive_regulation of Eif2ak3 1 0.00 0.73 0.23
132 INT169611 Binding of RAN and OGFR 1 0.24 0.19 0.23
133 INT187485 Trib3 Positive_regulation of Prkag1 1 0.00 0.97 0.22
134 INT339903 Binding of SCN5A and ZGLP1 1 0.01 0.18 0.22
135 INT29257 Pomc Positive_regulation of Gcg 1 0.17 0.23 0.21
136 INT285979 Ros1 Positive_regulation of Trib3 2 0.02 2.18 0.2
137 INT51345 Binding of Vtn and Pomc 1 0.03 0 0.2
138 INT179937 Trib3 Regulation of TNF 1 0.00 0.59 0.2
139 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
140 INT343837 TICAM1 Positive_regulation of IRF3 1 0.03 0.19 0.19
141 INT343831 TICAM1 Positive_regulation of Gene_expression of TLR4 1 0.11 0.19 0.19
142 INT23585 Binding of KRIT1 and CCR1 1 0.40 0.97 0.19
143 INT28562 SOD1 Negative_regulation of Pacs1 1 0.03 2.63 0.19
144 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
145 INT23586 Binding of CALCR and KRIT1 1 0.40 0.97 0.19
146 INT345209 Repin1 Positive_regulation of Positive_regulation of Trib3 1 0.00 0.88 0.18
147 INT280052 Negative_regulation of Dpp4 Positive_regulation of Zglp1 1 0.03 0.72 0.18
148 INT75355 Negative_regulation of GCG Regulation of Gh 1 0.01 1.26 0.18
149 INT140870 Binding of Trib3 and Gtf3a 1 0.00 0.07 0.18
150 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18
151 INT75356 GCG Regulation of Gh 1 0.01 1.25 0.18
152 INT98775 Abhd5 Regulation of Localization of Gcg 1 0.24 0 0.17
153 INT343852 Binding of TRAF1 and TICAM1 1 0.03 0.19 0.17
154 INT164790 Cdk5r1 Positive_regulation of Trib3 1 0.02 0.25 0.17
155 INT343850 Binding of TRAF4 and TICAM1 1 0.03 0.19 0.17
156 INT343915 Binding of Traf1 and TICAM1 1 0.08 0.19 0.17
157 INT71547 ADRA2C Positive_regulation of Localization of GCG 1 0.01 0.14 0.17
158 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
159 INT125770 GLP1R Negative_regulation of Localization of GCG 2 0.29 0.65 0.16
160 INT146841 Tnf Positive_regulation of Trib3 1 0.03 0.77 0.16
161 INT309125 Trib3 Positive_regulation of Rorb 1 0.00 0.16 0.16
162 INT158613 Binding of Serpine1 and Vtn 1 0.02 0.95 0.16
163 INT15524 GCG Negative_regulation of FFAR1 1 0.07 0.35 0.16
164 INT146845 Tnf Positive_regulation of Positive_regulation of Trib3 1 0.03 0.77 0.16
165 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15
166 INT106009 Binding of VTN and Plaur 1 0.05 1.37 0.15
167 INT260059 AKTIP Positive_regulation of TRPA1 1 0.02 0 0.15
168 INT153185 Prok2 Regulation of Trib3 1 0.02 0 0.15
169 INT136605 Binding of OPRD1 and RAN 1 0.37 0.54 0.15
170 INT136606 Binding of RAN and DLL1 1 0.33 0.45 0.15
171 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
172 INT1233 Gcg Positive_regulation of Pdpk1 1 0.27 0 0.14
173 INT300512 Binding of Plau and Vtn 1 0.06 2.28 0.13
174 INT300511 Binding of Plaur and Vtn 1 0.10 2.28 0.13
175 INT352450 Tnc Regulation of Trib3 1 0.00 0.22 0.13
176 INT300513 Binding of Serpine1 and Vtn 1 0.17 2.27 0.13
177 INT133349 Positive_regulation of Trib3 Positive_regulation of Gene_expression of Qrfp 1 0.02 0 0.12
178 INT177675 Binding of CALM1 and Positive_regulation of Trib3 1 0.00 0.27 0.12
179 INT324831 Binding of TRIM63 and Ticam1 1 0.01 0.09 0.12
180 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12
181 INT254229 Binding of Ticam1 and Positive_regulation of Binding of IFNA1 1 0.02 0.3 0.12
182 INT254207 Ticam1 Positive_regulation of Ik 1 0.00 0.14 0.12
183 INT246687 Binding of Ros1 and Zglp1 1 0.05 0.18 0.12
184 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
185 INT177674 CALM1 Positive_regulation of Trib3 1 0.00 0.27 0.12
186 INT332685 Trib3 Positive_regulation of Binding of Ros1 1 0.01 0.74 0.12
187 INT285981 Ros1 Regulation of Positive_regulation of Trib3 1 0.01 0.95 0.12
188 INT254227 Binding of Ripk1 and Ticam1 3 0.07 0.18 0.11
189 INT254215 Binding of Tlr4 and Ticam1 2 0.09 0.76 0.11
190 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
191 INT334264 Binding of Gtf3a and Ticam1 1 0.00 0.18 0.11
192 INT254220 Binding of Ticam1 and Sarm1 1 0.09 0.22 0.11
193 INT324869 Binding of Jun and Ticam1 1 0.01 0.76 0.11
194 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
195 INT321983 Glp1r Negative_regulation of Localization of Gcg 1 0.09 1.36 0.11
196 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
197 INT324870 Binding of Ticam1 and Tlr3 1 0.03 0.76 0.11
198 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1
199 INT278156 Negative_regulation of Trib3 Negative_regulation of Akt1 1 0.00 0.45 0.1
200 INT245185 Binding of RRAD and TCF7L2 1 0.00 6.88 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein binding. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01
2 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48
3 INT1473 Localization of Gcg 95 0.80 17.35 30.31
4 INT12681 Regulation of Trib3 76 0.53 23.92 26.58
5 INT17625 Localization of GCG 210 0.80 55.69 24.97
6 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27
7 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58
8 INT38253 Localization of Trib3 35 0.63 10.28 15.42
9 INT109031 Positive_regulation of Eif2ak3 44 0.69 21.11 14.72
10 INT109034 Gene_expression of Eif2ak3 37 0.77 17.11 14.19
11 INT6575 Positive_regulation of Localization of Gcg 33 0.69 3.48 13.31
12 INT2586 Positive_regulation of Gcg 35 0.70 9.25 11.75
13 INT33127 Positive_regulation of Phosphorylation of Trib3 26 0.17 14.04 10
14 INT8740 Localization of Gcg 65 0.78 19 9.81
15 INT4494 Regulation of GCG 41 0.45 18.38 9.68
16 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48
17 INT10533 Positive_regulation of Positive_regulation of Trib3 24 0.42 6.59 9.2
18 INT63701 Localization of KRIT1 11 0.78 2.02 9.17
19 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
20 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
21 INT150678 Positive_regulation of Gene_expression of Eif2ak3 17 0.69 6.64 8.99
22 INT3658 Regulation of Gcg 28 0.53 12.89 8.58
23 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35
24 INT2587 Regulation of Localization of Gcg 22 0.60 1.73 7.59
25 INT3659 Negative_regulation of Gcg 26 0.51 10.08 7.39
26 INT38254 Positive_regulation of Localization of Trib3 14 0.45 6.14 6.99
27 INT15528 Positive_regulation of GCG 38 0.63 20.47 6.14
28 INT36757 Gene_expression of Eif2ak3 4 0.74 0.15 6.06
29 INT3894 Negative_regulation of Localization of Gcg 18 0.52 2.7 5.77
30 INT31227 Regulation of Localization of GCG 28 0.48 4.86 5.72
31 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68
32 INT50704 Binding of Trib3 13 0.31 6.33 5.46
33 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98
34 INT51734 Negative_regulation of Localization of Trib3 10 0.19 2.53 4.97
35 INT137336 Phosphorylation of Eif2ak3 14 0.79 4.72 4.78
36 INT2213 Regulation of EP300 10 0.54 4.72 4.5
37 INT24813 Negative_regulation of Positive_regulation of Trib3 10 0.16 1.3 4.48
38 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46
39 INT8743 Positive_regulation of Gcg 19 0.65 10.63 4.43
40 INT1634 Gene_expression of Gcg 25 0.75 14.98 4.42
41 INT8744 Regulation of Localization of Gcg 14 0.60 2.06 4.3
42 INT32205 Regulation of Positive_regulation of Trib3 9 0.11 2.82 4.1
43 INT17626 Positive_regulation of Localization of GCG 36 0.69 13.94 4.06
44 INT5602 Positive_regulation of Eif2ak3 9 0.66 0 4.04
45 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
46 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
47 INT10535 Positive_regulation of Gene_expression of Trib3 13 0.59 4.93 3.74
48 INT8748 Positive_regulation of Localization of Gcg 24 0.67 9.74 3.46
49 INT31414 Gene_expression of Gcg 25 0.73 7.28 3.25
50 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
51 INT24821 Binding of VTN 14 0.47 5.83 3
52 INT15327 Negative_regulation of Phosphorylation of Trib3 7 0.30 4.95 2.99
53 INT219564 Positive_regulation of Zglp1 18 0.46 5.19 2.87
54 INT33492 Negative_regulation of Negative_regulation of Trib3 5 0.30 0.51 2.67
55 INT203819 Binding of Eif2ak3 9 0.37 5.94 2.57
56 INT15695 Positive_regulation of EIF2AK3 12 0.67 7.01 2.56
57 INT57244 Positive_regulation of Caprin2 5 0.13 3.44 2.39
58 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
59 INT36758 Positive_regulation of Gene_expression of Eif2ak3 1 0.48 0 2.21
60 INT43282 Binding of Gcg 5 0.32 0.61 2.18
61 INT249563 Positive_regulation of Trib3 1 0.45 0.94 2.18
62 INT249555 Localization of Trib3 1 0.73 0.94 2.18
63 INT56705 Negative_regulation of Positive_regulation of Gcg 1 0.51 0 2.17
64 INT15983 Regulation of Gcg 6 0.58 1.67 2.16
65 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
66 INT171514 Binding of EP300 13 0.32 4.32 2.01
67 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97
68 INT36755 Positive_regulation of Localization of Eif2ak3 1 0.48 0 1.97
69 INT36756 Localization of Eif2ak3 1 0.71 0 1.96
70 INT134919 Binding of Ticam1 6 0.18 1.12 1.94
71 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
72 INT150675 Regulation of Gene_expression of Eif2ak3 3 0.40 1.11 1.93
73 INT8745 Negative_regulation of Gcg 13 0.40 4.84 1.91
74 INT48218 Gene_expression of KRIT1 16 0.75 7.59 1.8
75 INT63029 Gene_expression of Vtn 4 0.14 2.8 1.8
76 INT36759 Regulation of Gene_expression of Eif2ak3 1 0.59 0 1.74
77 INT172622 Localization of EP300 8 0.65 2.56 1.72
78 INT127524 Localization of Zglp1 9 0.53 4.28 1.7
79 INT32469 Regulation of Gene_expression of Trib3 5 0.07 2.33 1.7
80 INT28954 Binding of GCG 7 0.36 3.14 1.68
81 INT48752 Regulation of Negative_regulation of Trib3 3 0.39 0.89 1.65
82 INT26180 Regulation of Regulation of GCG 3 0.39 1.43 1.65
83 INT6438 Positive_regulation of RAN 6 0.42 2.09 1.59
84 INT109033 Positive_regulation of Positive_regulation of Eif2ak3 2 0.45 2.36 1.59
85 INT98773 Negative_regulation of Localization of Gcg 10 0.53 9.59 1.5
86 INT87272 Binding of KRIT1 4 0.47 1.2 1.48
87 INT150677 Negative_regulation of Eif2ak3 9 0.58 6.24 1.46
88 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
89 INT246677 Gene_expression of Zglp1 10 0.51 4.26 1.39
90 INT99639 Regulation of Phosphorylation of Trib3 6 0.14 0.44 1.36
91 INT215864 Localization of Eif2ak3 5 0.75 3.26 1.36
92 INT18337 Transcription of Eif2ak3 3 0.68 0 1.36
93 INT57245 Negative_regulation of Positive_regulation of Caprin2 1 0.01 1.03 1.27
94 INT118682 Positive_regulation of KRIT1 4 0.67 1.25 1.24
95 INT24819 Positive_regulation of VTN 8 0.49 3.52 1.23
96 INT127900 Phosphorylation of EIF2AK3 14 0.80 7.99 1.22
97 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
98 INT83061 Regulation of Localization of Trib3 2 0.07 0.11 1.17
99 INT137338 Regulation of Eif2ak3 8 0.45 5.5 1.07
100 INT10264 Regulation of Regulation of Gcg 2 0.39 0 1.05
101 INT152404 Regulation of PKD1 2 0.45 2.02 1.04
102 INT87273 Positive_regulation of Localization of KRIT1 1 0.67 0.1 1.02
103 INT167650 Binding of Ep300 1 0.09 0.14 1
104 INT134917 Localization of Ticam1 2 0.51 0.6 0.99
105 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
106 INT230251 Binding of FKBP1A 6 0.28 2.24 0.94
107 INT238448 Binding of Zglp1 4 0.24 2.07 0.93
108 INT273038 Regulation of Vtn 3 0.08 2.26 0.91
109 INT48931 Regulation of Regulation of Trib3 2 0.04 0.06 0.89
110 INT240368 Positive_regulation of Localization of Eif2ak3 1 0.34 0.66 0.87
111 INT134912 Positive_regulation of Localization of Ticam1 1 0.24 0.32 0.87
112 INT109032 Negative_regulation of Positive_regulation of Eif2ak3 1 0.38 0.94 0.85
113 INT219590 Negative_regulation of Zglp1 4 0.39 1.93 0.83
114 INT127899 Gene_expression of EIF2AK3 8 0.75 2.89 0.8
115 INT154053 Negative_regulation of Gene_expression of Eif2ak3 2 0.43 1.28 0.79
116 INT85678 Binding of Arrb1 1 0.20 0.09 0.78
117 INT127901 Positive_regulation of Gene_expression of EIF2AK3 3 0.49 1.8 0.77
118 INT246674 Protein_catabolism of Zglp1 3 0.66 1.21 0.76
119 INT43857 Regulation of Gene_expression of GCG 2 0.25 0.64 0.76
120 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74
121 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
122 INT31413 Regulation of Regulation of Gcg 1 0.25 0 0.73
123 INT71599 Phosphorylation of KRIT1 1 0.79 0 0.73
124 INT246666 Negative_regulation of Protein_catabolism of Zglp1 1 0.28 0.51 0.69
125 INT127898 Positive_regulation of Phosphorylation of EIF2AK3 3 0.49 2.03 0.67
126 INT87717 Negative_regulation of Regulation of Gcg 1 0.02 0 0.67
127 INT51336 Binding of Vtn 3 0.12 1.5 0.66
128 INT246665 Regulation of Zglp1 1 0.30 0.71 0.64
129 INT197832 Localization of MEN1 1 0.80 11.01 0.63
130 INT346193 Positive_regulation of Gene_expression of VTN 1 0.25 1.54 0.63
131 INT238450 Transcription of Gcg 2 0.52 0.37 0.62
132 INT314618 Binding of ZGLP1 2 0.16 1.7 0.59
133 INT18168 Protein_catabolism of Gcg 4 0.99 1.17 0.56
134 INT280038 Negative_regulation of Localization of Zglp1 3 0.10 1.13 0.55
135 INT15526 Positive_regulation of Gene_expression of GCG 3 0.38 1.64 0.53
136 INT63028 Positive_regulation of Gene_expression of Vtn 1 0.03 1.01 0.53
137 INT5601 Regulation of Eif2ak3 1 0.43 0 0.53
138 INT83550 Negative_regulation of Gene_expression of Gcg 2 0.42 1.52 0.52
139 INT306058 Positive_regulation of ZGLP1 5 0.21 2.1 0.51
140 INT246670 Positive_regulation of Localization of Zglp1 3 0.46 0.98 0.5
141 INT102336 Gene_expression of Krit1 3 0.69 2.54 0.49
142 INT18336 Positive_regulation of Positive_regulation of Eif2ak3 1 0.33 0 0.49
143 INT238453 Positive_regulation of Gene_expression of Gcg 5 0.38 1.99 0.48
144 INT219592 Positive_regulation of Positive_regulation of Zglp1 3 0.31 0.1 0.46
145 INT83548 Negative_regulation of Positive_regulation of GCG 1 0.42 1.06 0.46
146 INT238452 Binding of Gcg 1 0.32 0.38 0.46
147 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
148 INT43909 Positive_regulation of Gene_expression of Gcg 3 0.48 1.45 0.45
149 INT61102 Gene_expression of MEN1 12 0.78 17.7 0.43
150 INT43910 Regulation of Gene_expression of Gcg 3 0.27 3.71 0.41
151 INT142598 Negative_regulation of KRIT1 3 0.57 0.57 0.4
152 INT340606 Positive_regulation of Wnt3a 1 0.61 0.49 0.4
153 INT15696 Regulation of EIF2AK3 2 0.26 1.1 0.39
154 INT156120 Localization of Arrb1 1 0.00 0 0.38
155 INT156119 Positive_regulation of Localization of Arrb1 1 0.00 0 0.38
156 INT238449 Negative_regulation of Gene_expression of Gcg 5 0.37 1.94 0.37
157 INT250167 Negative_regulation of Ticam1 3 0.29 2.03 0.37
158 INT71598 Positive_regulation of Gene_expression of KRIT1 1 0.49 0 0.37
159 INT77416 Localization of ZGLP1 3 0.79 1.79 0.36
160 INT51340 Binding of Vtn 2 0.22 1.38 0.36
161 INT45708 Positive_regulation of Positive_regulation of GCG 1 0.48 0.76 0.35
162 INT187587 Binding of Ep300 11 0.35 2.37 0.34
163 INT207064 Gene_expression of Fkbp1a 2 0.32 1.52 0.34
164 INT47340 Regulation of Positive_regulation of GCG 1 0.45 0 0.34
165 INT15697 Negative_regulation of EIF2AK3 1 0.41 0 0.33
166 INT207065 Localization of Fkbp1a 1 0.36 0.82 0.33
167 INT235610 Negative_regulation of Caprin2 1 0.07 1.12 0.32
168 INT113894 Positive_regulation of Protein_catabolism of Gcg 1 0.25 0.32 0.32
169 INT15698 Transcription of EIF2AK3 1 0.52 0 0.32
170 INT238585 Binding of EPB41 1 0.47 0.06 0.31
171 INT127902 Negative_regulation of Gene_expression of EIF2AK3 1 0.42 0.47 0.3
172 INT118046 Regulation of RAN 2 0.34 0.14 0.29
173 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28
174 INT202802 Regulation of Fkbp1a 4 0.26 0.96 0.28
175 INT51514 Positive_regulation of Wnt3a 3 0.04 3.32 0.28
176 INT35283 Negative_regulation of Vtn 2 0.21 0.34 0.27
177 INT50750 Transcription of Gcg 1 0.53 0.85 0.25
178 INT254195 Gene_expression of Ticam1 3 0.29 0.46 0.24
179 INT230957 Positive_regulation of CALD1 3 0.45 1.88 0.24
180 INT310936 Phosphorylation of GCG 1 0.10 1 0.24
181 INT238584 Positive_regulation of Binding of EPB41 1 0.49 0 0.24
182 INT280035 Regulation of Gene_expression of Zglp1 1 0.07 1.29 0.24
183 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
184 INT246668 Regulation of Positive_regulation of Zglp1 1 0.30 0.38 0.24
185 INT317236 Regulation of Localization of Zglp1 1 0.11 0 0.23
186 INT336382 Protein_catabolism of ZGLP1 1 0.08 0.76 0.23
187 INT303671 Negative_regulation of Regulation of GCG 1 0.13 1.44 0.22
188 INT210859 Gene_expression of EPB41 8 0.75 1.46 0.21
189 INT235611 Regulation of Caprin2 3 0.08 1.32 0.21
190 INT213438 Gene_expression of CALD1 2 0.31 0.39 0.21
191 INT264796 Regulation of Binding of GCG 1 0.04 0.16 0.21
192 INT169619 Negative_regulation of RAN 1 0.28 0.2 0.21
193 INT146414 Binding of Pacs1 2 0.30 0.06 0.2
194 INT310369 Protein_catabolism of Trib3 2 0.01 0.43 0.2
195 INT182647 Positive_regulation of EPB41 2 0.01 0.77 0.2
196 INT212787 Negative_regulation of Binding of EP300 1 0.13 0.53 0.2
197 INT114371 Negative_regulation of Tcf7l2 1 0.05 0.7 0.2
198 INT256666 Regulation of Gene_expression of EP300 1 0.14 0.07 0.2
199 INT146413 Positive_regulation of Binding of Pacs1 1 0.40 0.06 0.2
200 INT256661 Regulation of Positive_regulation of EP300 1 0.23 0.07 0.2
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