GO:0032099

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Name negative regulation of appetite
Categary Process
Go Slim No
Go Link GO:0032099
Unique Molecular Interactions 842
Total Molecular Interactions 1199
Total Single Events 13730
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of appetite. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of appetite. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10161 Binding of Cck and Penk 6 0.53 0.97 11.15
2 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
3 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53
4 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
5 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
6 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78
7 INT1151 Binding of CCK and GAST 7 0.49 0.73 3.08
8 INT28235 Binding of Cck and Gast 5 0.38 0.73 2.96
9 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88
10 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
11 INT30133 Binding of Cck and Penk 1 0.27 2.49 2.71
12 INT151381 St8sia1 Positive_regulation of Cck 1 0.19 0.45 2.7
13 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
14 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
15 INT111789 Cck Regulation of Gene_expression of Penk 1 0.49 1.68 2.57
16 INT111786 Penk Regulation of Gene_expression of Cck 1 0.49 1.66 2.55
17 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39
18 INT214159 Cck Positive_regulation of Nts 1 0.03 0.93 2.34
19 INT14781 Cck Regulation of Gast 3 0.38 0.28 2.3
20 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
21 INT5486 Oprd1 Regulation of Cck 1 0.21 0 2.16
22 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
23 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
24 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
25 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
26 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
27 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
28 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
29 INT82867 Cck Regulation of Localization of Pgc 1 0.05 0 1.83
30 INT90658 Abat Regulation of Localization of Cck 2 0.24 0 1.64
31 INT30743 Cck Regulation of Localization of Acot1 1 0.02 0 1.64
32 INT67966 Cck Positive_regulation of Adarb1 2 0.03 0 1.63
33 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
34 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
35 INT42001 Cck Regulation of Vip 1 0.28 0 1.51
36 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
37 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
38 INT27932 Binding of CCK and NCOR2 1 0.01 0.91 1.47
39 INT118812 Cck Positive_regulation of Rvm 1 0.21 0.65 1.46
40 INT27123 Binding of Pomc and Cck 2 0.31 0 1.38
41 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
42 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
43 INT116102 Cck Positive_regulation of Negative_regulation of Pnoc 1 0.51 0.41 1.33
44 INT91305 Binding of Npff and Npffr2 2 0.31 0.64 1.32
45 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
46 INT57956 LOC365260 Negative_regulation of Cck 1 0.11 0 1.3
47 INT30744 Sst Regulation of Cck 1 0.28 0.43 1.27
48 INT47956 Cck Positive_regulation of Gast 1 0.02 0.09 1.25
49 INT71070 Positive_regulation of Oprl1 Positive_regulation of Gene_expression of Cck 1 0.26 0 1.24
50 INT82754 Cck Positive_regulation of Positive_regulation of Pomc 1 0.39 0.3 1.21
51 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
52 INT203016 CCK Positive_regulation of Localization of PYY 3 0.68 1.19 1.17
53 INT253827 Cck Regulation of Cartpt 1 0.41 0 1.16
54 INT34422 Cck Positive_regulation of Negative_regulation of Npepo 1 0.31 0 1.14
55 INT21267 Cck Negative_regulation of Binding of Oprd1 1 0.50 0 1.12
56 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
57 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11
58 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11
59 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
60 INT40451 Cck Regulation of Prl 1 0.49 0 1.09
61 INT60783 Binding of Oprd1 and Cck 1 0.26 0.47 1.09
62 INT60584 Positive_regulation of Htr3a Positive_regulation of Localization of Cck 1 0.52 0.43 1.09
63 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04
64 INT101443 Penk Positive_regulation of Localization of Gcg 1 0.50 1.21 1.04
65 INT56743 LIF Positive_regulation of Cck 1 0.08 0.18 1.02
66 INT83903 Penk Positive_regulation of Npff 1 0.49 0 1.02
67 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
68 INT11251 Negative_regulation of Cck Positive_regulation of Fos 2 0.48 0 1
69 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
70 INT5612 Cck Positive_regulation of Localization of Crh 1 0.65 0.16 1
71 INT6077 Cck Negative_regulation of Localization of Penk 1 0.06 0 0.99
72 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
73 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
74 INT11392 Cck Positive_regulation of Cckbr 1 0.52 0 0.96
75 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
76 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95
77 INT53823 Cck Regulation of Localization of Pdyn 1 0.09 0 0.95
78 INT53822 Cck Regulation of Pdyn 1 0.02 0 0.95
79 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
80 INT253826 Cck Regulation of Nts 1 0.21 0.36 0.94
81 INT161769 Cck Regulation of Cckar 1 0.27 0.53 0.92
82 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91
83 INT85485 Phax Regulation of Gene_expression of Cck 1 0.07 0.61 0.91
84 INT41863 Avp Regulation of Cck 1 0.00 0 0.84
85 INT41859 Agtr2 Regulation of Cck 1 0.00 0 0.84
86 INT2881 SST Negative_regulation of Positive_regulation of CCK 1 0.32 0.1 0.84
87 INT41869 GRP Regulation of Cck 1 0.00 0 0.84
88 INT2880 SST Negative_regulation of CCK 1 0.32 0.1 0.84
89 INT41866 Nts Regulation of Cck 1 0.01 0 0.84
90 INT41861 Vip Regulation of Cck 1 0.02 0 0.84
91 INT67908 Binding of Cck and Plxna3 1 0.04 0.54 0.84
92 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82
93 INT73032 Cck Negative_regulation of Localization of Oxt 1 0.44 0 0.82
94 INT101439 Cck Positive_regulation of Agtr2 1 0.24 0.33 0.8
95 INT131650 Cck Positive_regulation of Fosl1 1 0.17 0 0.8
96 INT142454 Npff Positive_regulation of Gtpbp4 1 0.56 0 0.78
97 INT142455 Binding of Npff and Gtpbp4 1 0.40 0 0.78
98 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
99 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
100 INT224403 Binding of CCK and GYPC 1 0.04 0.83 0.77
101 INT139409 Cck Negative_regulation of Abat 1 0.14 0.5 0.76
102 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
103 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
104 INT31642 POMC Regulation of GCG 1 0.41 0.62 0.73
105 INT253828 Creb1 Positive_regulation of Gene_expression of Cartpt 1 0.19 0.15 0.72
106 INT101676 Sst Negative_regulation of Localization of Gcg 1 0.03 0 0.72
107 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72
108 INT72318 Adarb1 Positive_regulation of Positive_regulation of Cck 1 0.04 0 0.72
109 INT253829 Atf6b Positive_regulation of Gene_expression of Cartpt 1 0.24 0.15 0.72
110 INT253833 Positive_regulation of Atf6b Positive_regulation of Gene_expression of Cartpt 1 0.24 0.15 0.72
111 INT101444 Penk Regulation of Localization of Gcg 1 0.45 0.77 0.71
112 INT12238 CCK Positive_regulation of CDH2 1 0.02 0 0.7
113 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
114 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
115 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
116 INT253831 Cck Positive_regulation of Gene_expression of Cartpt 1 0.48 0.23 0.69
117 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
118 INT209859 IL4 Positive_regulation of PPARA 1 0.22 1.66 0.69
119 INT253825 Cck Positive_regulation of Crh 1 0.74 0 0.69
120 INT22922 Penk Negative_regulation of Negative_regulation of Cck 1 0.48 0 0.68
121 INT253830 Cck Positive_regulation of Crh 1 0.38 0 0.68
122 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
123 INT169215 Binding of OPRM1 and CARTPT 1 0.00 0.22 0.67
124 INT11611 Cck Positive_regulation of Localization of Avp 1 0.09 0 0.67
125 INT84213 Cck Regulation of Cckbr 1 0.41 0 0.67
126 INT11612 Cck Positive_regulation of Avp 1 0.10 0 0.67
127 INT169213 Binding of EGFR and CARTPT 1 0.00 0.22 0.67
128 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
129 INT15322 Binding of Npy and Cck 1 0.26 0.45 0.66
130 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
131 INT31418 Positive_regulation of Adra2c Positive_regulation of Gcg 1 0.22 0 0.65
132 INT40450 Cck Regulation of Gnrhr 1 0.23 0 0.65
133 INT89757 SST Regulation of Regulation of CCK 1 0.21 0.37 0.64
134 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
135 INT356329 Crhr1 Regulation of Cea 1 0.09 0.31 0.64
136 INT114950 YY1 Positive_regulation of Positive_regulation of PPARA 1 0.52 0.25 0.64
137 INT356314 Binding of Crhr1 and ORF61 1 0.00 0 0.63
138 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62
139 INT45638 Cck Positive_regulation of Localization of Melm1 1 0.02 0 0.62
140 INT30902 GCG Positive_regulation of Localization of SST 1 0.11 0.05 0.62
141 INT45637 Cck Positive_regulation of Melm1 1 0.02 0 0.62
142 INT5614 Cck Regulation of Localization of Pomc 1 0.12 0.08 0.62
143 INT133707 Npff Positive_regulation of Npffr1 1 0.73 0.73 0.61
144 INT37905 Cck Negative_regulation of Binding of Nts 1 0.64 0 0.61
145 INT37906 Cck Negative_regulation of Nts 1 0.64 0 0.61
146 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
147 INT91306 Binding of Npff and Npffr1 1 0.23 0.17 0.6
148 INT75092 Cck Regulation of Localization of Sst 1 0.01 0 0.59
149 INT30742 Cck Regulation of Sst 1 0.10 0 0.59
150 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
151 INT98815 Binding of Crhr2 and Ucn 3 0.32 0.5 0.56
152 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
153 INT82869 Gast Positive_regulation of Localization of Cck 1 0.30 0 0.56
154 INT28119 Atm Negative_regulation of Cck 1 0.42 0 0.56
155 INT356321 Positive_regulation of Crhr1 Positive_regulation of Cea 1 0.19 0.37 0.56
156 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
157 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
158 INT82868 Cck Regulation of Pgc 1 0.05 0 0.55
159 INT356322 Positive_regulation of Crhr1 Positive_regulation of ORF61 1 0.00 0 0.54
160 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
161 INT211993 Binding of Ppara and Rorb 1 0.00 1.13 0.54
162 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54
163 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
164 INT80834 Oxt Regulation of Cck 1 0.13 0 0.53
165 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
166 INT56390 CCK Positive_regulation of Localization of POMC 1 0.14 0.06 0.52
167 INT90067 Binding of Oprd1 and Npff 1 0.20 0.09 0.52
168 INT130161 IgG-2a Positive_regulation of Gene_expression of Crhr1 1 0.01 0 0.52
169 INT130158 Pomc Regulation of Gene_expression of Crhr1 1 0.20 0 0.52
170 INT130163 Pomc Positive_regulation of Gene_expression of Crhr1 1 0.15 0 0.52
171 INT130159 IgG-2a Regulation of Gene_expression of Crhr1 1 0.01 0 0.52
172 INT165043 Drd2 Regulation of Cck 1 0.20 0 0.52
173 INT205030 Crh Positive_regulation of Crhr1 2 0.54 1.33 0.51
174 INT108466 RCBTB1 Positive_regulation of Cck 1 0.01 0.16 0.51
175 INT108467 GCG Positive_regulation of Cck 1 0.02 0.16 0.51
176 INT7849 Man2a2 Positive_regulation of Localization of Gcg 1 0.08 0 0.51
177 INT2462 CCK Regulation of Localization of GAST 1 0.09 0.21 0.51
178 INT56744 CNTF Positive_regulation of Cck 1 0.08 0.09 0.51
179 INT9169 Pomc Positive_regulation of Localization of Cck 1 0.29 0 0.5
180 INT58249 CCK Positive_regulation of Regulation of GAST 1 0.48 0.86 0.5
181 INT285688 Cpox Positive_regulation of PPARA 1 0.02 1 0.5
182 INT43275 Cck Negative_regulation of Binding of Sct 1 0.01 0.18 0.5
183 INT21371 pcp Negative_regulation of Localization of Cck 1 0.05 0 0.49
184 INT110300 Cartpt Regulation of Adarb1 1 0.14 0 0.49
185 INT89225 Calca Regulation of Localization of Cck 1 0.44 0 0.48
186 INT25524 Oprd1 Regulation of Localization of GCG 1 0.01 0.52 0.48
187 INT89224 Calca Regulation of Cck 1 0.44 0 0.48
188 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
189 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
190 INT61848 Npff Regulation of Localization of Avp 1 0.26 0.3 0.48
191 INT240441 Ltb4r1 Positive_regulation of PPARA 1 0.03 1.01 0.47
192 INT26009 Cck Negative_regulation of Positive_regulation of Cckbr 1 0.26 0 0.47
193 INT240442 Binding of PPARA and Ltb4r1 1 0.02 0.94 0.46
194 INT17603 Cck Negative_regulation of Positive_regulation of Pomc 1 0.35 0 0.46
195 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
196 INT55260 Cck Positive_regulation of Positive_regulation of Calm2 1 0.62 0 0.45
197 INT55261 Cck Regulation of Positive_regulation of Cckbr 1 0.18 0 0.45
198 INT56723 Sst Negative_regulation of Cck 1 0.48 0 0.43
199 INT40446 Cck Regulation of Gh1 1 0.36 0 0.43
200 INT203017 Binding of CCK and PYY 1 0.38 0.62 0.43

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of appetite. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of appetite. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT287 Localization of Cck 518 0.81 86.84 364.04
2 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41
3 INT3948 Regulation of Cck 291 0.62 58.07 255.88
4 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92
5 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78
6 INT2366 Binding of Cck 192 0.48 30.64 163.46
7 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
8 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25
9 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
10 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
11 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
12 INT8153 Regulation of Localization of Cck 52 0.62 11.22 54.83
13 INT122041 Binding of Ppara 308 0.48 189.17 51.48
14 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
15 INT2463 Localization of CCK 101 0.81 37.54 47.59
16 INT6544 Negative_regulation of Localization of Cck 67 0.59 8.05 47.23
17 INT5025 Positive_regulation of Gene_expression of Cck 63 0.70 10.96 47.11
18 INT2406 Gene_expression of CCK 85 0.78 28.04 46.67
19 INT7824 Regulation of Cck 39 0.62 5.31 39.28
20 INT12159 Transcription of Cck 46 0.72 9.36 37.58
21 INT4843 Gene_expression of Npff 50 0.78 12.92 36.37
22 INT103094 Binding of PPARA 308 0.47 177.26 34.75
23 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21
24 INT9796 Gene_expression of Cck 63 0.78 11.44 32.09
25 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6
26 INT1473 Localization of Gcg 95 0.80 17.35 30.31
27 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
28 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
29 INT2408 Regulation of CCK 37 0.61 10.01 26.66
30 INT7832 Localization of Cck 39 0.81 6.81 26.54
31 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
32 INT19986 Negative_regulation of Cck 31 0.59 4.32 24.99
33 INT17625 Localization of GCG 210 0.80 55.69 24.97
34 INT7827 Binding of Cck 32 0.48 4.66 23.73
35 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
36 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
37 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
38 INT1156 Binding of CCK 27 0.48 8.71 20.58
39 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
40 INT4841 Localization of Npff 26 0.80 4.36 19.91
41 INT9128 Regulation of Gene_expression of Cck 27 0.62 6.55 19.45
42 INT10286 Positive_regulation of Positive_regulation of Cck 20 0.70 4.05 18.46
43 INT16155 Positive_regulation of Npff 25 0.70 6.21 17.58
44 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
45 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
46 INT9751 Localization of Crhr1 26 0.78 10.47 15.69
47 INT1154 Negative_regulation of CCK 24 0.59 9.3 15.32
48 INT75908 Regulation of LEP 77 0.60 60.16 15.19
49 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
50 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
51 INT46582 Binding of Npff 20 0.48 1.49 13.99
52 INT4842 Regulation of Npff 13 0.54 4.59 13.62
53 INT6575 Positive_regulation of Localization of Gcg 33 0.69 3.48 13.31
54 INT122037 Regulation of Ppara 93 0.62 56.28 12.89
55 INT7852 Negative_regulation of Gene_expression of Cck 15 0.59 2.02 12.85
56 INT73641 Regulation of Lep 45 0.62 26.2 12.59
57 INT194462 Localization of Ppara 94 0.78 68.33 12.09
58 INT21467 Negative_regulation of Binding of Cck 18 0.57 2.84 11.91
59 INT2586 Positive_regulation of Gcg 35 0.70 9.25 11.75
60 INT82984 Gene_expression of Cartpt 27 0.78 3.93 11.55
61 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
62 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
63 INT12158 Regulation of Transcription of Cck 5 0.60 0.99 11.03
64 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99
65 INT14780 Regulation of Binding of Cck 9 0.49 4.33 10.83
66 INT173159 Localization of PPARA 96 0.74 64.55 10.26
67 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
68 INT8740 Localization of Gcg 65 0.78 19 9.81
69 INT10041 Protein_catabolism of Cck 18 0.96 2.71 9.81
70 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76
71 INT4494 Regulation of GCG 41 0.45 18.38 9.68
72 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48
73 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
74 INT2885 Positive_regulation of Localization of CCK 19 0.70 9.92 8.94
75 INT7572 Regulation of Crhr1 8 0.45 5.6 8.93
76 INT3658 Regulation of Gcg 28 0.53 12.89 8.58
77 INT82082 Localization of Lep 63 0.81 26.41 8.56
78 INT81597 Transcription of Npff 10 0.69 5.52 8.53
79 INT75907 Binding of LEP 53 0.46 46.65 8.44
80 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35
81 INT214106 Gene_expression of Cartpt 21 0.73 3.68 7.84
82 INT181817 Negative_regulation of Gene_expression of Ppara 58 0.58 43.24 7.67
83 INT7570 Transcription of Crhr1 7 0.66 6.6 7.6
84 INT2587 Regulation of Localization of Gcg 22 0.60 1.73 7.59
85 INT74326 Gene_expression of Crhr1 25 0.66 9.7 7.48
86 INT3659 Negative_regulation of Gcg 26 0.51 10.08 7.39
87 INT80161 Positive_regulation of Crhr1 13 0.67 9.66 7.33
88 INT17969 Negative_regulation of Regulation of Cck 9 0.43 1.03 7.04
89 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89
90 INT46276 Regulation of Positive_regulation of Cck 9 0.45 0.86 6.82
91 INT170922 Binding of Ppara 59 0.45 28.45 6.7
92 INT4840 Positive_regulation of Localization of Npff 7 0.69 0.79 6.69
93 INT12239 Regulation of Localization of CCK 11 0.62 6.03 6.61
94 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6
95 INT9753 Positive_regulation of Localization of Crhr1 8 0.49 1.72 6.55
96 INT85655 Gene_expression of Crhr1 17 0.68 9.34 6.31
97 INT15528 Positive_regulation of GCG 38 0.63 20.47 6.14
98 INT81596 Positive_regulation of Gene_expression of Npff 6 0.69 3.41 6.1
99 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96
100 INT7825 Positive_regulation of Localization of Cck 7 0.47 0.89 5.92
101 INT22630 Positive_regulation of Binding of Cck 4 0.48 2.27 5.92
102 INT3894 Negative_regulation of Localization of Gcg 18 0.52 2.7 5.77
103 INT86025 Positive_regulation of Positive_regulation of PPARA 34 0.52 22.89 5.74
104 INT31227 Regulation of Localization of GCG 28 0.48 4.86 5.72
105 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
106 INT86023 Transcription of PPARA 60 0.66 25.8 5.7
107 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
108 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56
109 INT65356 Localization of LEP 46 0.79 41.17 5.43
110 INT91338 Binding of Lep 31 0.48 26.86 5.39
111 INT102935 Regulation of Lep 31 0.60 18.47 5.24
112 INT122038 Transcription of Ppara 35 0.71 20.5 5.12
113 INT170927 Negative_regulation of Ppara 27 0.54 13.58 5.12
114 INT18857 Negative_regulation of Positive_regulation of Cck 8 0.59 2.62 5.06
115 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98
116 INT53959 Negative_regulation of Npff 6 0.57 0.55 4.86
117 INT6103 Positive_regulation of Negative_regulation of Cck 5 0.50 0.61 4.83
118 INT18245 Negative_regulation of Localization of Crhr1 4 0.17 0.28 4.81
119 INT7568 Negative_regulation of Crhr1 8 0.43 4.63 4.77
120 INT53442 Gene_expression of Npff 12 0.76 0.57 4.75
121 INT128069 Localization of Cartpt 6 0.81 0.65 4.75
122 INT85403 Transcription of Cck 3 0.68 3.07 4.72
123 INT97391 Binding of Lep 18 0.48 8.97 4.47
124 INT8743 Positive_regulation of Gcg 19 0.65 10.63 4.43
125 INT1634 Gene_expression of Gcg 25 0.75 14.98 4.42
126 INT197171 Negative_regulation of Binding of Ppara 15 0.43 11.51 4.41
127 INT78328 Positive_regulation of Gene_expression of CCK 5 0.70 3.84 4.38
128 INT46277 Positive_regulation of Regulation of Cck 5 0.70 1.35 4.31
129 INT8744 Regulation of Localization of Gcg 14 0.60 2.06 4.3
130 INT7826 Positive_regulation of Positive_regulation of Cck 3 0.50 0.15 4.28
131 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22
132 INT163581 Localization of Lep 27 0.79 18.99 4.08
133 INT17626 Positive_regulation of Localization of GCG 36 0.69 13.94 4.06
134 INT15673 Positive_regulation of Transcription of Cck 4 0.69 1.62 3.84
135 INT34476 Regulation of Regulation of Cck 3 0.34 0.71 3.78
136 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
137 INT18630 Transcription of CCK 9 0.71 3 3.73
138 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
139 INT114957 Positive_regulation of Transcription of PPARA 18 0.62 10.36 3.65
140 INT85537 Regulation of Crhr1 4 0.45 1.64 3.53
141 INT49203 Regulation of Protein_catabolism of Cck 2 0.38 1.33 3.52
142 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
143 INT253819 Negative_regulation of Cartpt 1 0.40 0.34 3.49
144 INT56864 Negative_regulation of Positive_regulation of Cck 4 0.43 1.03 3.47
145 INT8748 Positive_regulation of Localization of Gcg 24 0.67 9.74 3.46
146 INT12388 Negative_regulation of Crhr1 17 0.59 9.47 3.33
147 INT31414 Gene_expression of Gcg 25 0.73 7.28 3.25
148 INT89337 Negative_regulation of Gene_expression of CCK 4 0.58 3.14 3.21
149 INT127336 Positive_regulation of Transcription of Crhr1 3 0.48 3.37 3.19
150 INT147522 Positive_regulation of Gene_expression of Ppara 28 0.47 15.82 3.18
151 INT10869 Regulation of Npff 3 0.45 0.37 3.15
152 INT9794 Regulation of Gene_expression of Cck 5 0.43 1.49 3.1
153 INT187618 Localization of Ppara 13 0.70 6.91 3.09
154 INT2883 Negative_regulation of Localization of CCK 9 0.59 3.25 3.08
155 INT82913 Regulation of Ppara 15 0.61 10.66 3.03
156 INT38504 Negative_regulation of Regulation of Cck 2 0.42 0.17 2.89
157 INT9752 Regulation of Localization of Crhr1 3 0.44 0.36 2.82
158 INT78327 Positive_regulation of Positive_regulation of CCK 3 0.47 1.74 2.82
159 INT222961 Negative_regulation of Binding of PPARA 22 0.41 10.76 2.72
160 INT7853 Negative_regulation of Negative_regulation of Cck 5 0.42 0.81 2.7
161 INT100144 Negative_regulation of Positive_regulation of PPARA 17 0.49 12.71 2.68
162 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
163 INT57811 Regulation of Localization of Cck 3 0.60 2.17 2.62
164 INT112962 Regulation of Positive_regulation of Ppara 17 0.45 10.63 2.58
165 INT118374 Negative_regulation of Npff 2 0.42 0.59 2.56
166 INT147517 Negative_regulation of Gene_expression of Ppara 12 0.37 3.46 2.55
167 INT199798 Positive_regulation of BBS2 2 0.50 5.85 2.55
168 INT124746 Positive_regulation of Npff 2 0.50 1.13 2.44
169 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
170 INT215379 Positive_regulation of Binding of Ppara 15 0.66 8.04 2.36
171 INT53960 Negative_regulation of Localization of Npff 3 0.38 0.31 2.34
172 INT9795 Positive_regulation of Gene_expression of Cck 6 0.50 0.34 2.26
173 INT300587 Negative_regulation of Gene_expression of Cartpt 3 0.36 0.58 2.19
174 INT85464 Positive_regulation of Cartpt 5 0.70 0.62 2.18
175 INT43282 Binding of Gcg 5 0.32 0.61 2.18
176 INT56705 Negative_regulation of Positive_regulation of Gcg 1 0.51 0 2.17
177 INT15983 Regulation of Gcg 6 0.58 1.67 2.16
178 INT215378 Protein_catabolism of Ppara 12 0.86 5.12 2.14
179 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
180 INT23120 Regulation of Regulation of CCK 3 0.61 1.13 2.06
181 INT83392 Transcription of Lep 6 0.54 5.07 2.04
182 INT253822 Binding of Cartpt 1 0.35 0.16 1.92
183 INT8745 Negative_regulation of Gcg 13 0.40 4.84 1.91
184 INT173180 Positive_regulation of Binding of PPARA 14 0.49 3.66 1.88
185 INT258135 Gene_expression of CARTPT 3 0.40 5.25 1.88
186 INT211984 Regulation of Binding of Ppara 11 0.45 9.55 1.87
187 INT168269 Negative_regulation of Positive_regulation of Ppara 3 0.38 0.57 1.87
188 INT82983 Transcription of Cartpt 2 0.66 0.17 1.86
189 INT31148 Negative_regulation of Gene_expression of Cck 6 0.43 0.14 1.82
190 INT214096 Localization of Cartpt 3 0.76 0.62 1.8
191 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
192 INT173177 Positive_regulation of Localization of PPARA 21 0.49 12.61 1.74
193 INT7823 Negative_regulation of Binding of Cck 2 0.43 0.07 1.69
194 INT28954 Binding of GCG 7 0.36 3.14 1.68
195 INT40228 Regulation of Positive_regulation of Cck 2 0.17 0.31 1.68
196 INT81598 Regulation of Transcription of Npff 1 0.44 0.78 1.68
197 INT80162 Localization of Ucn 6 0.80 0.6 1.66
198 INT26180 Regulation of Regulation of GCG 3 0.39 1.43 1.65
199 INT214126 Negative_regulation of Gene_expression of Cartpt 5 0.35 0.66 1.57
200 INT20804 Regulation of Gene_expression of CCK 5 0.45 1.33 1.56
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