GO:0032129

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Name histone deacetylase activity (H3-K9 specific)
Categary Function
Go Slim No
Go Link GO:0032129
Unique Molecular Interactions 38
Total Molecular Interactions 48
Total Single Events 199
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for histone deacetylase activity (H3-K9 specific). They are ordered first by their pain relevance and then by number of times they were reported for histone deacetylase activity (H3-K9 specific). Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28722 Binding of T2 and Hdac11 1 0.11 0.14 0.18
2 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
3 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
4 INT200326 Hdac1 Negative_regulation of Lhcgr 1 0.03 0 0.12
5 INT200304 Hdac2 Negative_regulation of Rorb 1 0.00 0 0.12
6 INT200318 Hdac1 Negative_regulation of Transcription of Lhcgr 1 0.03 0 0.12
7 INT200346 Hdac2 Negative_regulation of Lhcgr 1 0.04 0 0.12
8 INT200306 Hdac1 Negative_regulation of Rorb 1 0.00 0 0.12
9 INT200332 Binding of Rcor2 and Hdac1 1 0.15 0.3 0.12
10 INT200347 Hdac2 Negative_regulation of Transcription of Lhcgr 1 0.04 0 0.12
11 INT28723 Negative_regulation of Binding of T2 and Hdac11 1 0.10 0.08 0.1
12 INT331790 Binding of gr and Hdac2 1 0.01 0.74 0.07
13 INT331791 Akt1 Negative_regulation of Hdac2 1 0.03 0.8 0.07
14 INT331798 Regulation of Binding of gr and Hdac2 1 0.02 0.75 0.07
15 INT277615 Positive_regulation of Binding of ZNF238 and Hdac3 1 0.38 0.06 0.07
16 INT277614 Binding of ZNF238 and Hdac3 1 0.29 0.06 0.07
17 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
18 INT319171 Binding of Cgn and Hdac1 1 0.00 0 0
19 INT196948 Hmga2 Positive_regulation of Hdac1 1 0.36 0.23 0
20 INT332881 Negative_regulation of Binding of Hdac3 and Ncor1 1 0.28 0.18 0
21 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
22 INT311398 Positive_regulation of Celf1 Positive_regulation of Hdac1 1 0.12 0.19 0
23 INT196946 Binding of E2f1 and Hdac1 1 0.26 0.65 0
24 INT235166 Binding of Hdac3 and Atxn1 1 0.02 0.28 0
25 INT332894 Binding of Ahrr and Hdac3 1 0.01 0.08 0
26 INT332896 Binding of Hdac3 and Ncor1 1 0.31 1.38 0
27 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0
28 INT332878 Hdac3 Negative_regulation of Gene_expression of Arntl 1 0.42 0.17 0
29 INT196956 Binding of Hmga2 and Hdac1 1 0.25 0.23 0
30 INT235167 Binding of Hdac3 and Ncor2 1 0.01 0.28 0
31 INT196941 Hdac1 Negative_regulation of Rb1 1 0.27 0.44 0
32 INT196944 Binding of Rb1 and Hdac1 1 0.24 0.4 0
33 INT301470 Binding of Smyd2 and Hdac1 1 0.35 0.31 0
34 INT319170 Casp3 Regulation of Hdac1 1 0.01 0.27 0
35 INT332892 Ncor1 Positive_regulation of Hdac3 1 0.45 0.18 0
36 INT332879 Negative_regulation of Ncor1 Positive_regulation of Hdac3 1 0.28 0.18 0
37 INT333684 Binding of Hr and Hdac1 1 0.19 0.56 0
38 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for histone deacetylase activity (H3-K9 specific). They are ordered first by their pain relevance and then by number of times they were reported in histone deacetylase activity (H3-K9 specific). Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT277591 Gene_expression of Hdac4 22 0.77 7.77 1.79
2 INT272884 Gene_expression of Hdac2 19 0.43 14.55 1.48
3 INT277581 Positive_regulation of Hdac4 4 0.50 1.47 1.25
4 INT272879 Negative_regulation of Hdac2 8 0.37 5.96 1.17
5 INT200250 Binding of Hdac2 6 0.22 2.97 0.76
6 INT272883 Positive_regulation of Gene_expression of Hdac2 5 0.30 4.64 0.7
7 INT272886 Negative_regulation of Gene_expression of Hdac2 4 0.23 4.63 0.69
8 INT272868 Positive_regulation of Hdac2 3 0.27 2.15 0.5
9 INT277579 Binding of Hdac4 1 0.37 3.84 0.38
10 INT196927 Binding of Hdac1 9 0.36 2.31 0.36
11 INT277604 Negative_regulation of Hdac4 4 0.51 2.89 0.36
12 INT277598 Regulation of Gene_expression of Hdac4 1 0.45 0.91 0.36
13 INT272882 Positive_regulation of Binding of Hdac2 2 0.20 1.12 0.32
14 INT196917 Gene_expression of Hdac1 15 0.71 3.66 0.28
15 INT277584 Negative_regulation of Gene_expression of Hdac4 1 0.43 0.85 0.21
16 INT277594 Positive_regulation of Localization of Hdac4 1 0.50 1.71 0.21
17 INT277593 Localization of Hdac4 1 0.75 2.07 0.2
18 INT277600 Positive_regulation of Gene_expression of Hdac4 1 0.60 0.48 0.2
19 INT298778 Phosphorylation of Hdac3 1 0.44 0.67 0.17
20 INT277601 Positive_regulation of Positive_regulation of Hdac4 1 0.50 0.18 0.16
21 INT266991 Regulation of Hdac2 2 0.07 0.74 0.15
22 INT277582 Regulation of Hdac4 1 0.45 0.36 0.14
23 INT265376 Gene_expression of Hdac3 4 0.51 1.8 0.13
24 INT196934 Negative_regulation of Hdac1 4 0.39 1.41 0.11
25 INT331783 Regulation of Negative_regulation of Hdac1 1 0.04 0.98 0.11
26 INT331785 Negative_regulation of Gene_expression of Hdac3 1 0.04 0.86 0.1
27 INT28720 Binding of Hdac11 1 0.26 0.07 0.09
28 INT331786 Negative_regulation of Binding of Hdac2 1 0.11 1.2 0.08
29 INT331784 Negative_regulation of Positive_regulation of Hdac2 1 0.11 0.52 0.05
30 INT277599 Phosphorylation of Hdac4 1 0.82 3.24 0.05
31 INT265372 Localization of Hdac3 3 0.55 0.6 0.04
32 INT265373 Regulation of Hdac3 2 0.17 1.1 0.03
33 INT331778 Regulation of Phosphorylation of Hdac2 1 0.11 0.49 0.03
34 INT331787 Phosphorylation of Hdac2 1 0.20 0.49 0.03
35 INT277595 Localization of Hdac1 4 0.73 0.81 0
36 INT265371 Binding of Hdac3 2 0.27 0.94 0
37 INT261751 Regulation of Hdac1 2 0.41 0 0
38 INT265375 Negative_regulation of Hdac3 1 0.36 0.78 0
39 INT319154 Transcription of Hdac1 1 0.66 0 0
40 INT319156 Negative_regulation of Gene_expression of Hdac1 1 0.39 0.22 0
41 INT277580 Regulation of Localization of Hdac4 1 0.39 0 0
42 INT277596 Phosphorylation of Hdac1 1 0.61 0.59 0
43 INT319169 Negative_regulation of Transcription of Hdac1 1 0.54 0 0
44 INT277577 Transcription of Hdac4 1 0.69 0 0
45 INT355198 Positive_regulation of Localization of Hdac1 1 0.19 0.48 0
46 INT350933 Gene_expression of Hdac11 1 0.33 0.12 0
47 INT319162 Regulation of Gene_expression of Hdac1 1 0.56 0 0
48 INT319152 Positive_regulation of Gene_expression of Hdac1 1 0.46 0 0
49 INT277603 Negative_regulation of Phosphorylation of Hdac4 1 0.43 0.39 0
50 INT311329 Positive_regulation of Hdac1 1 0.19 0.14 0
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