GO:0032137

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Name guanine/thymine mispair binding
Categary Function
Go Slim No
Go Link GO:0032137
Unique Molecular Interactions 44
Total Molecular Interactions 59
Total Single Events 363
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for guanine/thymine mispair binding. They are ordered first by their pain relevance and then by number of times they were reported for guanine/thymine mispair binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21
2 INT29207 Msh2 Regulation of POMC 1 0.02 0.1 0.14
3 INT182607 Binding of MLH1 and MSH3 1 0.04 0.81 0.11
4 INT190044 Binding of Msh2 and Msh6 2 0.32 0.77 0.05
5 INT190050 Binding of Msh2 and Pms2 2 0.32 0.49 0.04
6 INT290556 Binding of MLH1 and MSH2 3 0.34 2.74 0
7 INT190061 Binding of MLH1 and Mlh1 1 0.01 0.92 0
8 INT57107 Binding of Msh2 and Nts 1 0.22 0.22 0
9 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0
10 INT300616 Binding of MLH1 and PMS2 1 0.36 0.53 0
11 INT277136 Ebp Positive_regulation of Gene_expression of Mlh1 1 0.01 1.45 0
12 INT190049 Binding of Mlh1 and Msh3 1 0.24 0.22 0
13 INT190048 Binding of Mlh1 and Msh2 1 0.31 0.22 0
14 INT212525 MSH6 Positive_regulation of Binding of C1qa 1 0.00 0.38 0
15 INT190062 Binding of MLH1 and Msh2 1 0.01 0.91 0
16 INT300617 Binding of MSH6 and MLH1 1 0.28 0.53 0
17 INT190047 Binding of Msh2 and Msh3 1 0.24 0.23 0
18 INT212528 Binding of MSH6 and Apcs 1 0.00 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for guanine/thymine mispair binding. They are ordered first by their pain relevance and then by number of times they were reported in guanine/thymine mispair binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7
2 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6
3 INT107985 Gene_expression of MLH1 29 0.67 31.31 1.46
4 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12
5 INT92139 Binding of MLH1 12 0.42 15.62 1
6 INT86907 Negative_regulation of MSH6 8 0.33 6.76 0.93
7 INT92142 Binding of MSH2 5 0.46 5.64 0.75
8 INT25176 Regulation of Msh2 3 0.37 0.48 0.68
9 INT25175 Gene_expression of Msh2 2 0.55 0.4 0.52
10 INT146545 Negative_regulation of Gene_expression of MSH2 17 0.56 18.87 0.51
11 INT107983 Gene_expression of MSH6 6 0.51 5.57 0.27
12 INT181920 Gene_expression of MSH3 2 0.50 2.54 0.18
13 INT182627 Regulation of MSH2 1 0.26 2.27 0.18
14 INT182621 Localization of MLH1 9 0.64 9.31 0.12
15 INT181744 Negative_regulation of Gene_expression of MLH1 3 0.05 7.67 0.12
16 INT147244 Regulation of MLH1 3 0.08 2.64 0.12
17 INT182623 Localization of MSH2 3 0.77 5.49 0.12
18 INT182626 Localization of MSH3 1 0.22 0.77 0.12
19 INT182622 Regulation of MSH3 1 0.08 0.77 0.12
20 INT181745 Positive_regulation of MSH2 4 0.48 5.73 0.11
21 INT15504 Positive_regulation of Msh2 1 0.33 0.15 0.09
22 INT190022 Positive_regulation of Mlh1 2 0.38 3.16 0.03
23 INT190039 Gene_expression of Mlh1 3 0.68 6.14 0
24 INT107991 Positive_regulation of Gene_expression of MSH6 3 0.38 1.35 0
25 INT190020 Gene_expression of Msh2 2 0.69 0.69 0
26 INT190038 Binding of Mlh1 2 0.28 3.11 0
27 INT212518 Localization of MSH6 2 0.10 2.66 0
28 INT190035 Binding of Msh6 2 0.28 2.72 0
29 INT211582 Transcription of Mlh1 1 0.41 0.34 0
30 INT206928 Transcription of MSH2 1 0.52 0.4 0
31 INT268375 Positive_regulation of Positive_regulation of MLH1 1 0.12 0.76 0
32 INT190012 Regulation of Mlh1 1 0.34 0.34 0
33 INT182625 Positive_regulation of Localization of MSH2 1 0.45 2.47 0
34 INT190058 Positive_regulation of Localization of MLH1 1 0.02 0.84 0
35 INT185286 Transcription of MLH1 1 0.06 1.12 0
36 INT350584 Negative_regulation of Gene_expression of Mlh1 1 0.51 2.21 0
37 INT190015 Binding of Msh2 1 0.27 1.41 0
38 INT305347 Negative_regulation of Gene_expression of Msh6 1 0.25 2.22 0
39 INT211715 Negative_regulation of Gene_expression of MSH6 1 0.06 1.09 0
40 INT268369 Positive_regulation of Negative_regulation of MLH1 1 0.11 0.76 0
41 INT107990 Positive_regulation of Gene_expression of MLH1 1 0.15 0 0
42 INT107984 Positive_regulation of Gene_expression of MSH2 1 0.11 0 0
43 INT182624 Positive_regulation of Positive_regulation of MSH2 1 0.45 1.24 0
44 INT211583 Regulation of Transcription of Mlh1 1 0.27 0.34 0
45 INT268359 Positive_regulation of MLH1 1 0.12 0.76 0
46 INT175425 Negative_regulation of Negative_regulation of MLH1 1 0.19 0.73 0
47 INT304071 Binding of MSH6 1 0.28 1.11 0
48 INT350588 Negative_regulation of Mlh1 1 0.38 3.05 0
49 INT305349 Gene_expression of Msh6 1 0.46 2.21 0
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