GO:0032227

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Name negative regulation of synaptic transmission, dopaminergic
Categary Process
Go Slim No
Go Link GO:0032227
Unique Molecular Interactions 191
Total Molecular Interactions 236
Total Single Events 3941
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of synaptic transmission, dopaminergic. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of synaptic transmission, dopaminergic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
2 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
3 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
4 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
5 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
6 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
7 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
8 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
9 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
10 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
11 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
12 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91
13 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
14 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
15 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
16 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
17 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76
18 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76
19 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
20 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74
21 INT333296 Gtf3a Regulation of Gene_expression of Slc6a4 1 0.01 0 0.74
22 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71
23 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
24 INT74727 Binding of Slc6a4 and Hpic1 1 0.00 0.49 0.68
25 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
26 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
27 INT333305 Zic2 Positive_regulation of Transcription of Slc6a4 1 0.68 0 0.66
28 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62
29 INT71942 Negative_regulation of PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.62
30 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62
31 INT71944 PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.61
32 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 0.19 1.38 0.58
33 INT137248 Slc6a14 Negative_regulation of Gene_expression of Ptgs2 1 0.19 1.32 0.58
34 INT125546 Arsa Negative_regulation of Gene_expression of PTGS2 1 0.00 0.53 0.58
35 INT87294 SERPINA3 Negative_regulation of PTGS2 1 0.25 0.6 0.58
36 INT333302 Zic2 Positive_regulation of Slc6a4 1 0.68 0.11 0.57
37 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
38 INT71943 Regulation of ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.54
39 INT129912 Skiv2l Negative_regulation of Gene_expression of PTGS2 1 0.00 0.87 0.54
40 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
41 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
42 INT71945 ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.53
43 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
44 INT69882 Ptger2 Positive_regulation of Gene_expression of Ptgs2 1 0.19 0.6 0.52
45 INT47745 Binding of Slc6a4 and Htr2a 1 0.33 0.09 0.52
46 INT116541 Binding of Ptgs2 and ZNF398 1 0.00 0.68 0.52
47 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
48 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
49 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
50 INT150205 Tnrc6a Negative_regulation of PTGS2 1 0.00 0.42 0.49
51 INT135584 CSF2 Regulation of PTGS2 1 0.06 1.28 0.49
52 INT150788 ZNF398 Regulation of PTGS2 1 0.02 0.5 0.48
53 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
54 INT62164 Il1b Positive_regulation of PTGS2 1 0.00 0.49 0.47
55 INT62163 Il1b Positive_regulation of Positive_regulation of PTGS2 1 0.00 0.49 0.47
56 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47
57 INT145436 Binding of HMOX2 and PTGS2 1 0.02 0.41 0.47
58 INT127662 Negative_regulation of PDE4A Negative_regulation of Gene_expression of PTGS2 1 0.15 0.75 0.47
59 INT113248 Olr1259 Negative_regulation of Slc6a4 1 0.00 0.23 0.44
60 INT106505 Binding of Ptgds and Ptgs2 1 0.01 0.93 0.39
61 INT200096 Negative_regulation of Il1a Negative_regulation of Gene_expression of Ptgs2 1 0.00 1.45 0.39
62 INT138938 Agrp Regulation of Pmch 1 0.35 0.1 0.38
63 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
64 INT157171 Binding of PTGS2 and Pla2g1b 1 0.02 0.26 0.37
65 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37
66 INT278766 HOXA9 Positive_regulation of Gene_expression of PTGS2 1 0.43 1.28 0.35
67 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35
68 INT89501 Il6 Positive_regulation of Ptgs2 1 0.01 1.07 0.35
69 INT89505 Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
70 INT134303 Cpox Negative_regulation of PTGS2 1 0.00 0.77 0.34
71 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
72 INT89502 Positive_regulation of Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
73 INT140666 TNF Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
74 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
75 INT52700 Prkcg Positive_regulation of Ptgs2 1 0.12 0.3 0.32
76 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31
77 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
78 INT64859 Negative_regulation of PTGS1 Negative_regulation of PTGS2 1 0.07 0.05 0.31
79 INT235877 Prkaca Regulation of Transcription of Slc6a4 1 0.06 0.13 0.31
80 INT116594 Negative_regulation of PTGS2 Negative_regulation of Gene_expression of IL6 1 0.22 0.45 0.31
81 INT139044 AKR1B1 Regulation of Gene_expression of PTGS2 1 0.09 0.37 0.3
82 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3
83 INT156084 Binding of PTGS2 and AKR1C3 1 0.02 0.31 0.3
84 INT62207 Binding of PTGS1 and PTGS2 3 0.06 0.07 0.29
85 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 0.01 0.84 0.29
86 INT235874 Camk2a Positive_regulation of Slc6a4 1 0.11 0.14 0.28
87 INT243214 Myst2 Negative_regulation of Gene_expression of Ptgs2 1 0.01 1.4 0.28
88 INT91751 Binding of PTGS2 and Hmox1 1 0.00 0.21 0.27
89 INT142447 PTGS2 Regulation of Gene_expression of PTGIS 1 0.30 0.24 0.27
90 INT107392 PTGS2 Positive_regulation of PTGS1 2 0.31 1.01 0.26
91 INT114069 Negative_regulation of Agtr2 Positive_regulation of Ptgs2 1 0.08 0.49 0.26
92 INT69120 MOCS1 Regulation of PTGS2 1 0.00 0.39 0.26
93 INT96402 Binding of PTGS2 and TBXAS1 1 0.02 0.32 0.26
94 INT64860 PTGS1 Negative_regulation of PTGS2 1 0.07 0 0.26
95 INT96401 Binding of PTGER1 and PTGS2 1 0.00 0.32 0.26
96 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25
97 INT102625 IL6 Regulation of Gene_expression of PTGS2 1 0.11 0.29 0.24
98 INT136798 Spp1 Regulation of Gene_expression of PTGS2 1 0.08 0.65 0.24
99 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
100 INT166663 Mpzl2 Negative_regulation of Positive_regulation of Ptgs2 1 0.29 0.3 0.24
101 INT102617 PTAFR Regulation of Gene_expression of PTGS2 1 0.12 0.29 0.24
102 INT132382 Nos2 Positive_regulation of PTGS2 1 0.02 0.1 0.23
103 INT272143 PTAFR Positive_regulation of Gene_expression of PTGS2 1 0.12 1.59 0.23
104 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
105 INT145014 Positive_regulation of GAST Positive_regulation of PTGS2 1 0.31 0.51 0.22
106 INT133164 Ptgs2 Regulation of Tnf 1 0.14 0.98 0.22
107 INT145012 GAST Positive_regulation of PTGS2 1 0.42 0.51 0.22
108 INT112134 Gast Positive_regulation of Gene_expression of Ptgs2 1 0.28 0.19 0.21
109 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
110 INT69318 ST3GAL4 Positive_regulation of Gene_expression of PTGS2 1 0.35 0.09 0.21
111 INT112136 Egf Positive_regulation of Gene_expression of Ptgs2 1 0.21 0.19 0.21
112 INT333298 Zic2 Regulation of Transcription of Slc6a4 1 0.44 0.09 0.2
113 INT283747 Tbs1 Positive_regulation of Ptgs2 1 0.00 0 0.2
114 INT231639 Binding of PTGER2 and PTGS2 1 0.00 0.44 0.19
115 INT117517 PROC Positive_regulation of PTGS2 1 0.01 0.61 0.19
116 INT79651 PTGS2 Positive_regulation of Phosphorylation of NR3C1 1 0.07 0.1 0.19
117 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19
118 INT139015 STAT1 Negative_regulation of Gene_expression of PTGS2 1 0.01 0.36 0.19
119 INT73332 IL1B Positive_regulation of Transcription of PTGS2 1 0.44 0.54 0.18
120 INT73331 PTAFR Positive_regulation of Transcription of PTGS2 1 0.13 0.54 0.18
121 INT119130 Binding of Nos2 and Ptgs2 1 0.33 0.07 0.17
122 INT354819 Binding of Cpox and Ptgs2 1 0.02 0.45 0.16
123 INT69317 PTGS2 Positive_regulation of Gene_expression of PTGS1 1 0.42 0.09 0.16
124 INT141753 Nfkb1 Regulation of Ptgs2 1 0.16 1.18 0.16
125 INT146745 UGCG Positive_regulation of Gene_expression of PTGS2 1 0.23 0.1 0.16
126 INT141754 Nfkb1 Regulation of Positive_regulation of Ptgs2 1 0.16 1.21 0.16
127 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
128 INT176621 PTGS2 Regulation of Gene_expression of PTGER2 1 0.00 0.09 0.15
129 INT87710 MYB Regulation of PTGS2 1 0.28 0.64 0.15
130 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
131 INT92342 Zfp697 Negative_regulation of Ptgs2 1 0.02 0.63 0.15
132 INT138321 PPA1 Positive_regulation of Gene_expression of PTGS2 1 0.02 0.09 0.14
133 INT141111 Sftpa1 Positive_regulation of Ptgs2 1 0.64 0.3 0.14
134 INT328851 Binding of PTGS2 and ZNF434 1 0.00 0.7 0.14
135 INT141112 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.39 0.31 0.14
136 INT144027 Binding of Slc6a4 and Pdgfrb 1 0.23 0.25 0.14
137 INT81983 IL1A Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.27 0.13
138 INT306270 CCL4 Positive_regulation of Transcription of PTGS2 1 0.34 0.31 0.12
139 INT173129 PTGS2 Regulation of IER3 1 0.01 0.36 0.12
140 INT306262 NFKB1 Positive_regulation of Transcription of PTGS2 1 0.42 0.31 0.12
141 INT63521 Negative_regulation of Ptgs2 Negative_regulation of Gene_expression of Fos 1 0.66 0.1 0.12
142 INT117568 Dspp Negative_regulation of Ptgs2 1 0.11 0.13 0.12
143 INT147073 NFKB1 Regulation of PTGS2 1 0.37 0 0.11
144 INT133361 FABP6 Negative_regulation of PTGS2 1 0.01 0.07 0.11
145 INT52701 Slc3a1 Positive_regulation of Ptgs2 1 0.06 0.27 0.11
146 INT52702 Capza2 Positive_regulation of Ptgs2 1 0.00 0.27 0.11
147 INT294454 KLK4 Negative_regulation of PTGS2 1 0.01 0 0.1
148 INT87922 Gm7869 Negative_regulation of Ptgs2 1 0.01 0.56 0.1
149 INT327557 Pla2g4a Positive_regulation of Phosphorylation of Ptgs2 1 0.14 1.03 0.1
150 INT327559 Pla2g4a Positive_regulation of Gene_expression of Ptgs2 1 0.14 1 0.09
151 INT249465 Positive_regulation of Slc6a4 Positive_regulation of Gene_expression of Bdnf 1 0.31 0.3 0.08
152 INT268325 Lep Positive_regulation of Ptgs2 1 0.09 0.39 0.08
153 INT249466 Slc6a4 Positive_regulation of Phosphorylation of Creb1 1 0.09 0.36 0.07
154 INT140895 PTGS2 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.07 0.07
155 INT98715 HGF Positive_regulation of Gene_expression of PTGS2 1 0.02 1.03 0.07
156 INT333304 Zic2 Positive_regulation of Gene_expression of Slc6a4 1 0.68 0.1 0.06
157 INT333297 Gtf3a Positive_regulation of Gene_expression of Slc6a4 1 0.01 0.1 0.06
158 INT341882 Positive_regulation of Oxtr Positive_regulation of Positive_regulation of Ptgs2 1 0.02 0.11 0.05
159 INT321652 Binding of Slc6a3 and Slc6a4 1 0.26 0.07 0.05
160 INT321654 Binding of Slc6a4 and Uts2r 1 0.05 0.07 0.05
161 INT17850 Binding of PTGS2 and Ptgs2 1 0.00 0.08 0.04
162 INT17851 Negative_regulation of Binding of PTGS2 and Ptgs2 1 0.00 0.08 0.04
163 INT333301 Binding of Slc6a4 and Zic2 1 0.47 0 0.03
164 INT331157 Ptgis Positive_regulation of Ptgs2 1 0.04 0.77 0.03
165 INT333307 Gene_expression of Zic2 Positive_regulation of Gene_expression of Slc6a4 1 0.45 0.05 0.03
166 INT322236 Agt Regulation of Gene_expression of Slc6a4 1 0.42 0.63 0
167 INT322251 Slc6a4 Regulation of Gene_expression of Agtrap 1 0.43 0.63 0
168 INT127457 Ccl2 Positive_regulation of Gene_expression of Slc6a4 1 0.13 0 0
169 INT346838 ZNF434 Regulation of PTGS2 1 0.01 0.34 0
170 INT121545 Mif Negative_regulation of Regulation of Ptgs2 1 0.13 0.15 0
171 INT346836 MECP2 Regulation of PTGS2 1 0.00 0.34 0
172 INT352066 Binding of PTGS2 and PTGES2 1 0.04 0 0
173 INT127464 Binding of PAH and Slc6a4 1 0.08 0 0
174 INT322248 Slc6a4 Regulation of Gene_expression of Agt 1 0.42 0.63 0
175 INT149883 Agtr2 Positive_regulation of Gene_expression of Ptgs2 1 0.06 0.31 0
176 INT240685 Binding of DIRAS3 and KCNQ4 1 0.18 0.95 0
177 INT343163 ACSL4 Regulation of Gene_expression of PTGS2 1 0.08 0.5 0
178 INT352064 Binding of PTGS2 and HPGDS 1 0.20 0 0
179 INT165863 Binding of HSPG2 and PTGS2 1 0.01 0.19 0
180 INT322238 Slc6a4 Regulation of Gene_expression of Ace 1 0.37 0.63 0
181 INT352065 Binding of PTGDS and PTGS2 1 0.28 0 0
182 INT322256 Ace Regulation of Gene_expression of Slc6a4 1 0.37 0.63 0
183 INT333306 Ephb1 Regulation of Gene_expression of Slc6a4 1 0.19 0.21 0
184 INT333295 Gtf3a Positive_regulation of Slc6a4 1 0.01 0 0
185 INT322247 Slc6a4 Regulation of Gene_expression of Htr2a 1 0.13 0.63 0
186 INT333300 Positive_regulation of Zic2 Positive_regulation of Slc6a4 1 0.45 0 0
187 INT143293 Negative_regulation of Nfkb1 Negative_regulation of Gene_expression of PTGS2 1 0.00 0 0
188 INT166070 PTGS2 Regulation of VEGFA 1 0.29 0.06 0
189 INT350068 Positive_regulation of Hmox1 Negative_regulation of Gene_expression of Ptgs2 1 0.03 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of synaptic transmission, dopaminergic. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of synaptic transmission, dopaminergic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
2 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
3 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
4 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
5 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
6 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
7 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
8 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
9 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
10 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
11 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
12 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
13 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
14 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
15 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
16 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
17 INT17848 Binding of PTGS2 70 0.46 32.1 20.6
18 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
19 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
20 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44
21 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39
22 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28
23 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
24 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39
25 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
26 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
27 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39
28 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
29 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53
30 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
31 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
32 INT119651 Binding of Slc6a4 12 0.32 4.65 7.07
33 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
34 INT90097 Localization of PTGS2 15 0.69 6.14 6.63
35 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52
36 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
37 INT67656 Positive_regulation of Positive_regulation of PTGS2 12 0.46 4.83 6.17
38 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
39 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86
40 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71
41 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
42 INT119711 Positive_regulation of Slc6a4 16 0.69 4.44 5.21
43 INT122675 Negative_regulation of Gene_expression of Slc6a4 14 0.59 6.4 4.69
44 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5
45 INT52616 Negative_regulation of Positive_regulation of PTGS2 13 0.43 4.95 4.13
46 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05
47 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
48 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81
49 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77
50 INT53200 Binding of Ptgs2 11 0.48 5.08 3.54
51 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28
52 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2
53 INT100190 Regulation of Gene_expression of Slc6a4 5 0.39 1.8 3.14
54 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
55 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97
56 INT68505 Positive_regulation of Negative_regulation of PTGS2 8 0.49 2.26 2.76
57 INT80320 Negative_regulation of Gene_expression of Slc6a4 4 0.42 0.85 2.6
58 INT127176 Transcription of Ptgs2 8 0.58 4.68 2.58
59 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48
60 INT120726 Positive_regulation of Gene_expression of Slc6a4 4 0.68 0.51 2.34
61 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3
62 INT152554 Regulation of Transcription of SLC6A4 3 0.62 1.52 2.18
63 INT97579 Negative_regulation of Localization of PTGS2 2 0.08 2.37 1.99
64 INT195430 Regulation of Positive_regulation of SLC6A4 1 0.42 1.01 1.98
65 INT125974 Localization of Slc6a4 5 0.66 2.27 1.97
66 INT77805 Regulation of Gene_expression of Ptgs2 6 0.51 2.7 1.92
67 INT52691 Positive_regulation of Transcription of Ptgs2 5 0.44 3 1.9
68 INT243017 Negative_regulation of Binding of Slc6a4 1 0.25 0.22 1.89
69 INT141937 Negative_regulation of Regulation of SLC6A4 1 0.41 0.27 1.8
70 INT147808 Positive_regulation of Gene_expression of SLC6A4 4 0.50 1.03 1.57
71 INT149622 Positive_regulation of Transcription of Ptgs2 3 0.28 2.48 1.46
72 INT190768 Regulation of Positive_regulation of Ptgs2 1 0.04 1.2 1.41
73 INT86823 Regulation of Transcription of PTGS2 3 0.19 1.48 1.4
74 INT135658 Phosphorylation of Ptgs2 2 0.23 1.39 1.34
75 INT101026 Positive_regulation of Negative_regulation of Ptgs2 2 0.35 1.01 1.23
76 INT179372 Positive_regulation of Localization of PTGS2 2 0.38 0.35 1.21
77 INT59078 Positive_regulation of Transcription of PTGS2 5 0.69 2.36 1.17
78 INT47839 Localization of Slc6a4 4 0.79 0.96 1.14
79 INT147286 Negative_regulation of Regulation of Slc6a4 1 0.21 0 1.13
80 INT62981 Protein_catabolism of PTGS2 5 0.78 1.09 1.11
81 INT64862 Negative_regulation of Negative_regulation of PTGS2 3 0.36 0.76 1.09
82 INT70505 Positive_regulation of Positive_regulation of Ptgs2 4 0.49 2.22 1.08
83 INT83647 Negative_regulation of Negative_regulation of Ptgs2 1 0.28 1.97 1.05
84 INT64177 Negative_regulation of Transcription of PTGS2 4 0.41 1.99 1.03
85 INT128444 Phosphorylation of SLC6A4 2 0.61 0.49 1.02
86 INT93296 Gene_expression of Pmch 6 0.64 0.48 1
87 INT129674 Regulation of Negative_regulation of Slc6a4 1 0.38 0.46 0.98
88 INT68265 Positive_regulation of Negative_regulation of Ptgs2 3 0.46 0.08 0.92
89 INT131649 Positive_regulation of Negative_regulation of Slc6a4 2 0.44 0.32 0.91
90 INT286694 Positive_regulation of Localization of Slc6a4 1 0.26 0 0.9
91 INT152101 Regulation of Transcription of Slc6a4 1 0.14 0 0.89
92 INT149624 Regulation of Transcription of Ptgs2 1 0.16 0.84 0.84
93 INT115770 Negative_regulation of Positive_regulation of Ptgs2 4 0.43 0.94 0.79
94 INT120057 Regulation of Localization of PTGS2 1 0.28 0.14 0.78
95 INT243015 Regulation of Binding of Slc6a4 1 0.16 0.43 0.75
96 INT147809 Localization of SLC6A4 5 0.71 1.69 0.74
97 INT71950 Positive_regulation of Binding of PTGS2 2 0.31 0.31 0.74
98 INT78957 Regulation of Transcription of Ptgs2 1 0.17 0.49 0.72
99 INT82544 Regulation of Positive_regulation of PTGS2 4 0.39 1.41 0.71
100 INT127175 Negative_regulation of Transcription of Ptgs2 3 0.47 2.11 0.7
101 INT92341 Localization of Ptgs2 5 0.75 2.04 0.64
102 INT286687 Phosphorylation of Slc6a4 1 0.46 0 0.58
103 INT286690 Positive_regulation of Phosphorylation of Slc6a4 1 0.28 0 0.58
104 INT115772 Positive_regulation of Localization of Ptgs2 1 0.46 0.5 0.55
105 INT115771 Positive_regulation of Positive_regulation of Ptgs2 1 0.46 0.5 0.54
106 INT106568 Regulation of Regulation of Slc6a4 1 0.22 0.07 0.52
107 INT271164 Negative_regulation of Transcription of Slc6a4 1 0.04 0.47 0.52
108 INT142835 Regulation of Localization of Ptgs2 2 0.25 0.26 0.5
109 INT129524 Regulation of Regulation of SLC6A4 1 0.26 0.16 0.5
110 INT352021 Negative_regulation of Negative_regulation of SLC6A4 1 0.08 0.2 0.5
111 INT150168 Negative_regulation of Transcription of SLC6A4 1 0.42 0.16 0.47
112 INT150167 Positive_regulation of Transcription of SLC6A4 1 0.45 0.16 0.46
113 INT94036 Negative_regulation of Transcription of Ptgs2 1 0.30 0.52 0.43
114 INT333278 Negative_regulation of Transcription of Slc6a4 2 0.37 0.56 0.36
115 INT140668 Positive_regulation of Negative_regulation of SLC6A4 1 0.56 0.23 0.36
116 INT82545 Positive_regulation of Regulation of PTGS2 1 0.19 0.15 0.35
117 INT148455 Positive_regulation of Negative_regulation of Slc6a4 1 0.50 0.18 0.34
118 INT124930 Positive_regulation of Binding of SLC6A4 1 0.40 0.06 0.33
119 INT341784 Positive_regulation of Phosphorylation of SLC6A4 1 0.29 0.07 0.26
120 INT148299 Negative_regulation of KCNQ4 2 0.11 0.37 0.24
121 INT79350 Positive_regulation of Binding of Slc6a4 1 0.34 0 0.24
122 INT340198 Regulation of Transcription of Slc6a4 1 0.36 0.66 0.22
123 INT103022 Positive_regulation of Transcription of Slc6a4 2 0.44 0.52 0.21
124 INT17849 Negative_regulation of Binding of PTGS2 2 0.38 0.16 0.2
125 INT148274 Negative_regulation of Regulation of PTGS2 1 0.01 0.47 0.19
126 INT87715 Negative_regulation of Negative_regulation of Ptgs2 1 0.16 0.68 0.17
127 INT247598 Regulation of Binding of Ptgs2 1 0.10 1.69 0.16
128 INT129433 Regulation of Binding of PTGS2 1 0.25 1.01 0.14
129 INT52697 Regulation of Positive_regulation of Ptgs2 2 0.27 0.34 0.13
130 INT254929 Gene_expression of KCNQ4 1 0.14 0 0.13
131 INT212801 Phosphorylation of Ptgs2 2 0.22 1.03 0.1
132 INT283729 Protein_catabolism of Ptgs2 1 0.01 0.09 0.08
133 INT332749 Positive_regulation of Binding of Slc6a4 1 0.23 0.19 0.07
134 INT254934 Negative_regulation of Gene_expression of KCNQ4 1 0.09 0 0.06
135 INT17845 Negative_regulation of Binding of Ptgs2 1 0.09 0.08 0.04
136 INT121544 Positive_regulation of Regulation of Ptgs2 1 0.14 0.15 0
137 INT333286 Negative_regulation of Positive_regulation of Slc6a4 1 0.50 0 0
138 INT333280 Regulation of Localization of Slc6a4 1 0.38 0.18 0
139 INT101927 Negative_regulation of Binding of Slc6a4 1 0.59 0 0
140 INT96041 Positive_regulation of Localization of Ptgs2 1 0.17 0.07 0
141 INT127454 Negative_regulation of Positive_regulation of Slc6a4 1 0.32 0 0
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