GO:0032232

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Name negative regulation of actin filament bundle assembly
Categary Process
Go Slim No
Go Link GO:0032232
Unique Molecular Interactions 39
Total Molecular Interactions 56
Total Single Events 193
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of actin filament bundle assembly. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of actin filament bundle assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95404 Map3k1 Positive_regulation of Phosphorylation of Ephb1 1 0.12 0.16 0.46
2 INT95408 Map3k1 Positive_regulation of Ephb1 1 0.12 0.16 0.46
3 INT354704 Binding of MAP3K1 and Pick1 1 0.00 0.76 0.41
4 INT255934 Tauph Positive_regulation of Map3k1 1 0.00 0.1 0.32
5 INT255946 MAPK14 Positive_regulation of Map3k1 1 0.04 0.1 0.32
6 INT274932 Binding of Insrr and Map3k1 1 0.00 0 0.28
7 INT274947 Binding of Map3k1 and Grip1 1 0.00 0 0.27
8 INT354968 Shank3 Positive_regulation of Gene_expression of Gria2 1 0.05 0 0.15
9 INT177916 PRKG1 Positive_regulation of Positive_regulation of MAP3K1 1 0.05 1.07 0.14
10 INT280488 Bdnf Positive_regulation of Gene_expression of Map3k1 1 0.01 1.49 0.11
11 INT303179 Binding of Dlgap1 and Shank1 1 0.22 0.31 0.1
12 INT92389 ALK Positive_regulation of Gene_expression of Map3k1 1 0.01 1.14 0.09
13 INT232559 Map3k1 Positive_regulation of Esr1 1 0.19 0.26 0.09
14 INT303180 Trim3 Negative_regulation of Shank1 1 0.40 0 0.09
15 INT354962 Gene_expression of Shank3 Positive_regulation of Gusb 1 0.10 0.45 0.08
16 INT303176 Gene_expression of Trim3 Positive_regulation of Protein_catabolism of Shank1 1 0.44 0 0.07
17 INT354963 Binding of Cttn and Shank1 1 0.12 0 0.04
18 INT354971 Binding of HOMER1 and Shank1 1 0.01 0 0.04
19 INT342726 Binding of Laptm5 and Park2 1 0.03 0.64 0.04
20 INT250025 Map3k1 Positive_regulation of Regulation of Bcl2 1 0.01 1.1 0.04
21 INT303170 Gene_expression of Trim3 Negative_regulation of Shank1 1 0.40 0.12 0.04
22 INT272594 Binding of Dlg4 and Shank1 1 0.20 0 0.03
23 INT317301 Binding of Park2 and Park7 1 0.36 0.62 0
24 INT303159 Trim3 Negative_regulation of Gene_expression of Shank1 1 0.40 0 0
25 INT342725 Pink1 Positive_regulation of Phosphorylation of Park2 1 0.29 0.62 0
26 INT215413 ITC1 Negative_regulation of MAP3K1 1 0.04 0.23 0
27 INT303185 Binding of Shank1 and Trim3 1 0.35 0 0
28 INT348521 TRAF2 Positive_regulation of MAP3K1 1 0.03 0.46 0
29 INT317300 Binding of Park2 and Pink1 1 0.48 1.23 0
30 INT342727 Pink1 Positive_regulation of Park2 1 0.29 0.62 0
31 INT348689 Fgf2 Regulation of Map3k1 1 0.09 0 0
32 INT303161 Gene_expression of Trim3 Positive_regulation of Shank1 1 0.44 0 0
33 INT317302 Binding of Park2 and Mul1 1 0.01 0.62 0
34 INT303169 Trim3 Regulation of Gene_expression of Shank1 1 0.42 0 0
35 INT215416 MAP3K1 Regulation of MAPK9 1 0.14 0.64 0
36 INT215412 Binding of MAP3K1 and ITC1 1 0.03 0 0
37 INT215415 MAP3K1 Regulation of MAPK8 1 0.62 0.64 0
38 INT303163 Shank1 Positive_regulation of Trim3 1 0.47 0 0
39 INT303173 Negative_regulation of Trim3 Negative_regulation of Shank1 1 0.40 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of actin filament bundle assembly. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of actin filament bundle assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT159121 Positive_regulation of Map3k1 10 0.45 8.79 2.6
2 INT95400 Negative_regulation of Map3k1 3 0.15 0.78 1.92
3 INT71788 Gene_expression of MAP3K1 13 0.70 4.9 1.66
4 INT50785 Gene_expression of Map3k1 6 0.44 4.22 1.32
5 INT128413 Positive_regulation of Shank1 2 0.70 0.61 1.16
6 INT128411 Regulation of Shank1 2 0.45 0.81 0.95
7 INT71784 Positive_regulation of Gene_expression of MAP3K1 4 0.34 4.8 0.82
8 INT50784 Positive_regulation of Gene_expression of Map3k1 2 0.06 0.94 0.8
9 INT177933 Positive_regulation of MAP3K1 6 0.42 4.13 0.76
10 INT354944 Negative_regulation of Shank3 1 0.59 1.18 0.59
11 INT111602 Negative_regulation of Gene_expression of MAP3K1 1 0.06 0.58 0.58
12 INT95401 Phosphorylation of Map3k1 1 0.21 0.16 0.46
13 INT354955 Gene_expression of Shank3 1 0.78 3.23 0.45
14 INT303211 Gene_expression of Shank1 1 0.64 0.48 0.4
15 INT102721 Negative_regulation of MAP3K1 2 0.53 8.03 0.3
16 INT354948 Regulation of Shank3 1 0.45 0.69 0.26
17 INT177941 Phosphorylation of MAP3K1 2 0.20 1.31 0.24
18 INT98785 Negative_regulation of Gene_expression of Map3k1 1 0.03 0.69 0.21
19 INT154200 Binding of Map3k1 1 0.06 0.32 0.16
20 INT303216 Protein_catabolism of Shank1 1 0.83 0 0.15
21 INT303217 Binding of Shank1 1 0.36 0 0.11
22 INT303233 Negative_regulation of Gene_expression of Shank1 1 0.49 0.07 0.1
23 INT173169 Regulation of MAP3K1 2 0.41 1.81 0.09
24 INT92387 Gene_expression of Map3k1 1 0.02 1.13 0.09
25 INT354949 Positive_regulation of Gene_expression of Shank3 1 0.70 0.45 0.08
26 INT354958 Localization of Shank3 1 0.80 0.4 0.08
27 INT342696 Gene_expression of Park2 1 0.65 1.19 0.08
28 INT303212 Positive_regulation of Protein_catabolism of Shank1 1 0.42 0 0.08
29 INT272574 Gene_expression of Shank1 2 0.61 0.22 0.06
30 INT303195 Positive_regulation of Gene_expression of Shank1 1 0.42 0.08 0.06
31 INT354959 Regulation of Gene_expression of Shank3 1 0.27 1.11 0.06
32 INT250022 Regulation of Map3k1 2 0.18 1.02 0.04
33 INT317299 Binding of Park2 1 0.36 0.61 0.04
34 INT303204 Negative_regulation of Shank1 1 0.42 0.11 0.04
35 INT202475 Positive_regulation of Positive_regulation of Map3k1 2 0.33 1.54 0
36 INT342695 Phosphorylation of Park2 1 0.79 0.62 0
37 INT303227 Regulation of Negative_regulation of Shank1 1 0.26 0 0
38 INT215426 Negative_regulation of Negative_regulation of MAP3K1 1 0.39 0.32 0
39 INT354953 Negative_regulation of Gene_expression of Shank3 1 0.59 0.36 0
40 INT354960 Binding of Shank3 1 0.32 0 0
41 INT189990 Negative_regulation of Map3k1 1 0.01 1.48 0
42 INT333617 Transcription of MAP3K1 1 0.23 0.09 0
43 INT215425 Positive_regulation of Negative_regulation of MAP3K1 1 0.45 0.78 0
44 INT303202 Negative_regulation of Protein_catabolism of Shank1 1 0.49 0 0
45 INT303209 Positive_regulation of Positive_regulation of Shank1 1 0.34 0 0
46 INT215419 Regulation of Localization of MAP3K1 1 0.41 0.22 0
47 INT303193 Localization of Shank1 1 0.62 0.19 0
48 INT215423 Localization of MAP3K1 1 0.68 0.22 0
49 INT303199 Regulation of Gene_expression of Shank1 1 0.23 0 0
50 INT354939 Positive_regulation of Gene_expression of Shank1 1 0.45 0.14 0
51 INT333621 Positive_regulation of Transcription of MAP3K1 1 0.16 0.09 0
52 INT215428 Binding of MAP3K1 1 0.44 0.05 0
53 INT303232 Regulation of Protein_catabolism of Shank1 1 0.38 0 0
54 INT202470 Negative_regulation of Positive_regulation of Map3k1 1 0.38 0.62 0
55 INT354946 Positive_regulation of Shank3 1 0.50 0 0
56 INT354938 Transcription of Shank3 1 0.69 0 0
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