GO:0032233

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Name positive regulation of actin filament bundle assembly
Categary Process
Go Slim No
Go Link GO:0032233
Unique Molecular Interactions 23
Total Molecular Interactions 28
Total Single Events 425
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of actin filament bundle assembly. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of actin filament bundle assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT124918 Binding of PLEK and Maob 1 0.10 1.05 0.98
2 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
3 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
4 INT81968 Binding of PLEK and Adra2a 1 0.07 0.1 0.7
5 INT310600 Tbxa2r Positive_regulation of PLEK 1 0.53 0.45 0.38
6 INT139566 Binding of PLEK and Tbxa2r 1 0.01 1.14 0.38
7 INT139565 Negative_regulation of Binding of PLEK and Tbxa2r 1 0.01 0.57 0.19
8 INT251347 Binding of Bmpr2 and Limk1 1 0.18 1.51 0.16
9 INT293698 Positive_regulation of Binding of Akt1 and Plek 1 0.05 0.12 0.15
10 INT293695 Binding of Akt1 and Plek 1 0.03 0.12 0.15
11 INT293699 Regulation of Binding of Akt1 and Plek 1 0.04 0.12 0.15
12 INT265919 Binding of PLEK and Adp 1 0.01 0.38 0.11
13 INT61385 FANCB Negative_regulation of PLEK 1 0.42 0.13 0.07
14 INT213060 Hdl1 Negative_regulation of Gene_expression of PLEK 1 0.25 1.33 0.05
15 INT347465 Binding of PLEK and ST7L 1 0.01 0 0.04
16 INT192227 VEGFA Positive_regulation of Phosphorylation of LIMK1 1 0.03 0.05 0
17 INT308131 PLEK Positive_regulation of F2 1 0.12 0.08 0
18 INT281320 Binding of PLEK and St8sia2 1 0.06 0.38 0
19 INT281322 Binding of PLEK and Tlr4 1 0.15 1.41 0
20 INT286682 Maob Positive_regulation of Positive_regulation of PLEK 1 0.51 0.89 0
21 INT354487 Binding of F9 and PLEK 1 0.52 0.14 0
22 INT275985 Binding of PLEK and Gp6 1 0.29 0 0
23 INT270084 Binding of PLEK and PSMG1 1 0.09 0.26 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of actin filament bundle assembly. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of actin filament bundle assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9296 Negative_regulation of PLEK 100 0.57 36.65 27.52
2 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47
3 INT18412 Binding of PLEK 49 0.47 17.82 10.72
4 INT3366 Localization of PLEK 44 0.78 15.83 9.55
5 INT10969 Positive_regulation of PLEK 33 0.67 16.96 8.35
6 INT12975 Regulation of PLEK 21 0.60 13.62 8.28
7 INT251332 Negative_regulation of Limk1 1 0.59 16.43 4.66
8 INT30001 Negative_regulation of Gene_expression of PLEK 8 0.57 3.31 2.47
9 INT33393 Positive_regulation of Gene_expression of PLEK 9 0.67 7.35 1.65
10 INT80086 Regulation of Gene_expression of PLEK 5 0.60 2.79 1.29
11 INT30002 Negative_regulation of Negative_regulation of PLEK 3 0.42 0.76 1.12
12 INT81220 Negative_regulation of Binding of PLEK 5 0.42 2.03 0.84
13 INT36881 Regulation of Positive_regulation of PLEK 2 0.44 1.77 0.84
14 INT18413 Positive_regulation of Binding of PLEK 3 0.49 1.06 0.77
15 INT3368 Positive_regulation of Localization of PLEK 3 0.45 0.51 0.77
16 INT42121 Negative_regulation of Localization of PLEK 4 0.42 1.92 0.61
17 INT251322 Positive_regulation of Limk1 1 0.50 2.05 0.55
18 INT45916 Regulation of Negative_regulation of PLEK 1 0.44 0 0.54
19 INT3367 Regulation of Localization of PLEK 1 0.44 0.34 0.52
20 INT251323 Negative_regulation of Gene_expression of Limk1 1 0.43 1.26 0.5
21 INT251326 Gene_expression of Limk1 1 0.67 1.87 0.47
22 INT182136 Regulation of Regulation of PLEK 1 0.44 0.4 0.44
23 INT323021 Positive_regulation of Regulation of PLEK 1 0.49 0.58 0.37
24 INT44345 Positive_regulation of Negative_regulation of PLEK 1 0.45 0.05 0.35
25 INT19700 Positive_regulation of Protein_catabolism of PLEK 1 0.49 0.59 0.3
26 INT19699 Protein_catabolism of PLEK 1 0.86 0.58 0.29
27 INT251325 Regulation of Negative_regulation of Limk1 1 0.62 2.3 0.29
28 INT251317 Binding of Limk1 1 0.37 1.69 0.23
29 INT42592 Negative_regulation of Transcription of PLEK 1 0.41 0 0.21
30 INT42593 Transcription of PLEK 1 0.67 0 0.2
31 INT108192 Regulation of Binding of PLEK 1 0.60 0.17 0.17
32 INT251318 Localization of Limk1 1 0.71 0.46 0.16
33 INT149305 Regulation of LIMK1 1 0.21 1 0.14
34 INT149304 Binding of LIMK1 1 0.13 1.05 0.14
35 INT16719 Positive_regulation of Positive_regulation of PLEK 1 0.45 0.13 0.14
36 INT251330 Regulation of Binding of Limk1 1 0.45 1.06 0.13
37 INT192242 Phosphorylation of LIMK1 4 0.61 0.34 0.04
38 INT343552 Gene_expression of LIMK1 1 0.65 0.15 0.04
39 INT251333 Regulation of Limk1 1 0.45 0 0
40 INT180099 Binding of Plek 1 0.02 0 0
41 INT192240 Positive_regulation of Phosphorylation of LIMK1 1 0.22 0.17 0
42 INT192241 Negative_regulation of Phosphorylation of LIMK1 1 0.14 0.06 0
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