GO:0032252

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Name secretory granule localization
Categary Process
Go Slim No
Go Link GO:0032252
Unique Molecular Interactions 60
Total Molecular Interactions 74
Total Single Events 375
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for secretory granule localization. They are ordered first by their pain relevance and then by number of times they were reported for secretory granule localization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132228 Negative_regulation of Binding of Pik3cg and Sh2d6 1 0.07 1.96 3.6
2 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
3 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
4 INT132227 Binding of Pik3cg and Sh2d6 1 0.06 0.49 0.9
5 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87
6 INT190178 PIK3CG Regulation of MMP12 1 0.09 0 0.65
7 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
8 INT117707 Oprm1 Positive_regulation of PIK3CG 1 0.00 0.08 0.6
9 INT335594 Myo5a Regulation of Hmmr 1 0.00 0.39 0.45
10 INT303948 LEPR Positive_regulation of PIK3CG 1 0.02 0.22 0.28
11 INT121581 Negative_regulation of PIK3CG Positive_regulation of GDF15 1 0.36 0.59 0.24
12 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
13 INT121580 PIK3CG Regulation of Gene_expression of GDF15 1 0.48 0.4 0.18
14 INT265892 IGF1 Positive_regulation of PIK3CG 1 0.18 1.96 0.16
15 INT203591 Positive_regulation of PIK3CG Positive_regulation of Protein_catabolism of LAMB2 1 0.00 0.46 0.14
16 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
17 INT129073 Binding of GRP and PIK3CG 1 0.00 0.49 0.12
18 INT257873 Ins1 Positive_regulation of Pik3cg 1 0.13 1.05 0.11
19 INT343855 Binding of MYD88 and PIK3CG 1 0.03 0.26 0.1
20 INT224021 PIK3CG Negative_regulation of EPHB2 1 0.03 0.5 0.09
21 INT57965 Myo5a Negative_regulation of Cyp2e1 1 0.01 0.09 0.07
22 INT267012 Pik3cg Positive_regulation of Arc 1 0.01 0.1 0.06
23 INT267013 Pik3cg Positive_regulation of Egr2 1 0.01 0.1 0.06
24 INT257875 Agt Positive_regulation of Pik3cg 1 0.06 0.37 0.04
25 INT257866 Phosphorylation of Rraga Positive_regulation of Pik3cg 1 0.03 0.63 0.03
26 INT257876 Rraga Positive_regulation of Pik3cg 1 0.03 0.63 0.03
27 INT265880 IGF1 Regulation of PIK3CG 1 0.10 1.23 0.03
28 INT267011 Pik3cg Regulation of Bdnf 1 0.06 0.07 0.03
29 INT176131 Binding of AKT1 and PIK3CG 2 0.15 1.08 0
30 INT201767 Igf1 Positive_regulation of PIK3CG 1 0.00 0.84 0
31 INT336033 PIK3CG Regulation of AKT1 1 0.03 0.43 0
32 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0
33 INT176137 Negative_regulation of Binding of AKT1 and PIK3CG 1 0.17 0.25 0
34 INT240420 Myo5a Positive_regulation of CD4 1 0.06 0.27 0
35 INT354122 MIR126 Regulation of PIK3CG 1 0.03 2.01 0
36 INT308352 Binding of Ctnnd2 and Tcf7l2 1 0.15 0.74 0
37 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0
38 INT262759 PIK3CG Positive_regulation of MTOR 1 0.38 0.54 0
39 INT225903 Binding of GAB1 and PIK3CG 1 0.01 0.13 0
40 INT201773 Binding of BCL2L1 and Positive_regulation of Negative_regulation of PIK3CG 1 0.01 0.3 0
41 INT225876 PIK3CG Positive_regulation of Ilk 1 0.00 0 0
42 INT293806 AR Positive_regulation of PIK3CG 1 0.06 0.12 0
43 INT304015 Binding of PIK3CA and PIK3CG 1 0.09 0.67 0
44 INT287269 Binding of ERBB3 and PIK3CG 1 0.11 0.74 0
45 INT293802 PTEN Regulation of PIK3CG 1 0.03 0.07 0
46 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0
47 INT223579 PTEN Negative_regulation of PIK3CG 1 0.18 0.56 0
48 INT293816 Binding of AR and PIK3CG 1 0.03 0.27 0
49 INT225894 Binding of MET and PIK3CG 1 0.00 0.13 0
50 INT201759 Ngf Positive_regulation of PIK3CG 1 0.01 0.84 0
51 INT262753 Binding of MTOR and PIK3CG 1 0.20 0.82 0
52 INT223578 INS Positive_regulation of PIK3CG 1 0.05 0.87 0
53 INT223576 PIK3CG Regulation of MTOR 1 0.15 0.37 0
54 INT223580 Positive_regulation of PIK3CG Regulation of MTOR 1 0.25 0.42 0
55 INT131787 Binding of Myo5a and Pon1 1 0.02 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for secretory granule localization. They are ordered first by their pain relevance and then by number of times they were reported in secretory granule localization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25
2 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
3 INT118274 Positive_regulation of Positive_regulation of PIK3CG 8 0.64 4.81 4.62
4 INT86919 Negative_regulation of PIK3CG 40 0.57 21.16 3.97
5 INT91887 Negative_regulation of Pik3cg 12 0.41 5.01 3.67
6 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16
7 INT148025 Localization of Pik3cg 1 0.58 0.69 2.34
8 INT148026 Positive_regulation of Pik3cg 4 0.45 0.54 1.46
9 INT311241 Transcription of Myo5a 1 0.50 1.61 1.37
10 INT155696 Gene_expression of PIK3CG 16 0.65 8.54 1.02
11 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93
12 INT57958 Positive_regulation of Myo5a 9 0.41 7.52 0.77
13 INT108204 Regulation of PIK3CG 9 0.12 4.16 0.75
14 INT190187 Regulation of Gene_expression of PIK3CG 1 0.13 0 0.65
15 INT132781 Phosphorylation of PIK3CG 8 0.52 4.83 0.53
16 INT133704 Regulation of Pik3cg 2 0.44 0.46 0.42
17 INT132780 Positive_regulation of Phosphorylation of PIK3CG 1 0.01 0.37 0.4
18 INT195574 Localization of Myo5a 4 0.34 1.1 0.36
19 INT176145 Positive_regulation of Gene_expression of PIK3CG 3 0.20 1.36 0.22
20 INT240411 Negative_regulation of Binding of Myo5a 1 0.09 0.97 0.21
21 INT114371 Negative_regulation of Tcf7l2 1 0.05 0.7 0.2
22 INT192783 Phosphorylation of Myo5a 1 0.04 2.01 0.12
23 INT160258 Negative_regulation of Myo5a 3 0.35 3.96 0.09
24 INT262775 Negative_regulation of Phosphorylation of PIK3CG 1 0.28 1.1 0.09
25 INT230866 Negative_regulation of Gene_expression of PIK3CG 2 0.28 1.37 0.07
26 INT192784 Positive_regulation of Gene_expression of Myo5a 2 0.45 3.39 0.04
27 INT341853 Negative_regulation of Negative_regulation of PIK3CG 1 0.14 0.85 0.04
28 INT257854 Positive_regulation of Positive_regulation of Pik3cg 1 0.27 0.11 0.04
29 INT257860 Regulation of Negative_regulation of Pik3cg 1 0.26 1.1 0.04
30 INT201693 Negative_regulation of Positive_regulation of PIK3CG 1 0.05 1.04 0.04
31 INT176162 Binding of PIK3CG 5 0.15 1.3 0.03
32 INT176151 Regulation of Negative_regulation of PIK3CG 2 0.28 0.92 0
33 INT210256 Positive_regulation of Tcf7l2 2 0.28 1.25 0
34 INT256098 Negative_regulation of Phosphorylation of Pik3cg 1 0.12 0.16 0
35 INT256090 Phosphorylation of Pik3cg 1 0.24 0.16 0
36 INT286005 Positive_regulation of Binding of Myo5a 1 0.41 0.97 0
37 INT286004 Positive_regulation of Positive_regulation of Myo5a 1 0.41 0.58 0
38 INT193985 Regulation of Phosphorylation of PIK3CG 1 0.03 0.32 0
39 INT176159 Regulation of Positive_regulation of PIK3CG 1 0.18 0.21 0
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