GO:0032269

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Name negative regulation of cellular protein metabolic process
Categary Process
Go Slim No
Go Link GO:0032269
Unique Molecular Interactions 457
Total Molecular Interactions 698
Total Single Events 4237
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cellular protein metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of cellular protein metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
3 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
4 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
5 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
6 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
7 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
8 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
9 INT116092 TFF2 Positive_regulation of NFKB1 1 0.17 0.06 1.77
10 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
11 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
12 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
13 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
14 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
15 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
16 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
17 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
18 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
19 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
20 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
21 INT147448 ADCYAP1 Regulation of Localization of NFKB1 1 0.47 1.12 1.15
22 INT101715 PLAT Positive_regulation of NFKB1 2 0.11 0.99 1.09
23 INT105113 Plat Positive_regulation of NFKB1 1 0.03 1.06 1.06
24 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
25 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
26 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
27 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
28 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
29 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
30 INT152388 Binding of NFKB1 and OPRM1 1 0.04 0.14 0.94
31 INT152389 Negative_regulation of Binding of NFKB1 and OPRM1 1 0.05 0.14 0.94
32 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
33 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
34 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87
35 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
36 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
37 INT161305 NFKB1 Positive_regulation of IL2 1 0.25 0.25 0.83
38 INT106312 NFKB1 Regulation of S100A4 1 0.14 1.1 0.83
39 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
40 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
41 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
42 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
43 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
44 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
45 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
46 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
47 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
48 INT140966 NFKB1 Positive_regulation of Positive_regulation of CPOX 1 0.08 0.66 0.8
49 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
50 INT146463 TNFSF10 Positive_regulation of NFKB1 2 0.08 2.45 0.71
51 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
52 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
53 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
54 INT103134 DCSTAMP Positive_regulation of NFKB1 2 0.07 1.43 0.7
55 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
56 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
57 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
58 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
59 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
60 INT153921 Positive_regulation of Adra2a Regulation of Ednrb 1 0.01 0 0.66
61 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
62 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
63 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64
64 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
65 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
66 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
67 INT120851 NFKB1 Positive_regulation of Localization of TNF 3 0.04 2.05 0.62
68 INT66207 Positive_regulation of TNF Positive_regulation of NFKB1 1 0.42 0.08 0.61
69 INT144248 CGA Regulation of Positive_regulation of NFKB1 1 0.15 1.66 0.61
70 INT144256 CGA Regulation of Gene_expression of NFKB1 1 0.21 1.66 0.61
71 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6
72 INT131642 Edn1 Positive_regulation of Positive_regulation of Insrr 1 0.01 0.44 0.6
73 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
74 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
75 INT147071 NFKB1 Regulation of Gene_expression of PTGES 1 0.36 0.35 0.57
76 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
77 INT113548 NFKB1 Regulation of Localization of PLAU 1 0.26 1.93 0.55
78 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
79 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
80 INT156246 NFKB1 Regulation of Gene_expression of TNF 1 0.17 0.35 0.54
81 INT105111 Negative_regulation of Plat Positive_regulation of NFKB1 1 0.03 0.53 0.54
82 INT105110 Cxcl12 Positive_regulation of NFKB1 1 0.06 0.54 0.53
83 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53
84 INT105108 Negative_regulation of Cxcl12 Positive_regulation of NFKB1 1 0.05 0.54 0.53
85 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
86 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
87 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
88 INT130157 Pomc Regulation of Gene_expression of Ednrb 1 0.14 0 0.52
89 INT139834 NFKB1 Regulation of Gene_expression of SELE 1 0.18 0.49 0.5
90 INT139835 NFKB1 Regulation of SELE 1 0.41 0.49 0.5
91 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
92 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
93 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
94 INT106072 NFKB1 Positive_regulation of Gene_expression of A2M 1 0.19 0.75 0.49
95 INT135588 Positive_regulation of IKBKE Positive_regulation of NFKB1 1 0.18 1.29 0.48
96 INT135587 IKBKE Positive_regulation of NFKB1 1 0.18 1.28 0.48
97 INT191948 NFKB1 Regulation of Gene_expression of NOS2 1 0.38 1 0.47
98 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
99 INT106073 IL1B Positive_regulation of Positive_regulation of NFKB1 1 0.41 0.7 0.47
100 INT253997 Binding of Cd200r1 and Mif 1 0.03 1.02 0.46
101 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
102 INT50497 Edn1 Positive_regulation of Pla2g1b 1 0.01 0.23 0.45
103 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
104 INT144245 CGA Negative_regulation of Positive_regulation of NFKB1 1 0.13 0.79 0.45
105 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
106 INT103128 Positive_regulation of DCSTAMP Positive_regulation of NFKB1 1 0.07 0.73 0.43
107 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
108 INT153766 Edn1 Positive_regulation of Gtf3a 1 0.04 1.25 0.41
109 INT107699 IL1B Positive_regulation of Localization of NFKB1 1 0.03 0.13 0.41
110 INT84516 NFKB1 Positive_regulation of Gene_expression of TF 1 0.10 0.09 0.41
111 INT103131 Positive_regulation of NFKB1 Regulation of Gene_expression of IL8 1 0.27 0.68 0.4
112 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
113 INT166788 HRAS Negative_regulation of Phosphorylation of NFKB1 1 0.08 0.5 0.39
114 INT99399 Penk Positive_regulation of Edn1 1 0.00 0 0.38
115 INT99400 Gast Positive_regulation of Edn1 1 0.00 0 0.38
116 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
117 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
118 INT103795 Negative_regulation of SLC9A1 Negative_regulation of Positive_regulation of NFKB1 1 0.12 0.47 0.37
119 INT107705 DCSTAMP Positive_regulation of Localization of NFKB1 1 0.07 0.07 0.36
120 INT152315 Ifng Regulation of Ednrb 1 0.19 0.22 0.36
121 INT152313 Il18 Regulation of Ednrb 1 0.30 0.22 0.36
122 INT152314 Il18 Regulation of Edn1 1 0.02 0.22 0.36
123 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
124 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
125 INT54570 Positive_regulation of NFKB1 Positive_regulation of Gene_expression of IL8 1 0.24 0.77 0.35
126 INT90388 NFKB1 Positive_regulation of CPOX 1 0.32 0.18 0.35
127 INT32212 POMC Regulation of Gene_expression of Mif 1 0.00 1.01 0.35
128 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
129 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
130 INT72953 Mif Positive_regulation of Localization of Prl 1 0.42 0 0.34
131 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
132 INT83347 GSR Negative_regulation of NFKB1 1 0.25 0.72 0.33
133 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
134 INT201484 Negative_regulation of Prkcg Negative_regulation of Positive_regulation of Ednrb 1 0.34 0.96 0.32
135 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
136 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32
137 INT72951 Mif Regulation of Prl 1 0.41 0 0.32
138 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32
139 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
140 INT182262 EDN1 Positive_regulation of Gene_expression of NOS2 1 0.28 0.79 0.31
141 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
142 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31
143 INT144251 TNF Positive_regulation of Gene_expression of NFKB1 1 0.43 0.65 0.3
144 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3
145 INT80029 Binding of FAS and Positive_regulation of NFKB1 1 0.34 0.92 0.3
146 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3
147 INT140386 Spp1 Positive_regulation of NFKB1 1 0.21 1.29 0.3
148 INT166789 HRAS Regulation of Positive_regulation of NFKB1 1 0.05 0.31 0.3
149 INT80031 FAS Positive_regulation of Positive_regulation of NFKB1 1 0.50 0.93 0.3
150 INT113558 Negative_regulation of NFKB1 Negative_regulation of Localization of PLAU 1 0.41 0.97 0.29
151 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28
152 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
153 INT196631 PTGER2 Negative_regulation of NFKB1 1 0.00 0.32 0.28
154 INT144237 Negative_regulation of DCSTAMP Positive_regulation of NFKB1 1 0.06 0.72 0.28
155 INT144255 EGF Regulation of Positive_regulation of NFKB1 1 0.41 0.66 0.27
156 INT144239 CTSG Regulation of Positive_regulation of NFKB1 1 0.00 0.67 0.27
157 INT72952 Mif Regulation of Localization of Prl 1 0.28 0 0.27
158 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27
159 INT56071 NFKB1 Positive_regulation of Gene_expression of IL1B 1 0.36 0.4 0.27
160 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26
161 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26
162 INT125514 Positive_regulation of PRKDC Positive_regulation of Positive_regulation of NFKB1 1 0.07 0.44 0.26
163 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
164 INT125512 Gene_expression of NFKB1 Positive_regulation of GDF15 1 0.32 0.42 0.25
165 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
166 INT321224 TLR4 Positive_regulation of NFKB1 1 0.04 1.02 0.25
167 INT120849 PRL Positive_regulation of NFKB1 1 0.07 0.49 0.25
168 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
169 INT321223 CXCR1 Positive_regulation of NFKB1 1 0.00 1.02 0.25
170 INT178095 EDN1 Positive_regulation of MMP3 1 0.04 0.88 0.24
171 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
172 INT178085 EDN1 Positive_regulation of MMP7 1 0.06 0.89 0.24
173 INT321222 Binding of NFKB1 and NFKBIZ 1 0.02 1.11 0.24
174 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24
175 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
176 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
177 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
178 INT125518 Binding of NFKB1 and GDF15 1 0.33 0.41 0.24
179 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24
180 INT125519 Regulation of PLAT Positive_regulation of NFKB1 1 0.07 0.44 0.24
181 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
182 INT143950 Negative_regulation of NFKB1 Positive_regulation of Gene_expression of RELA 1 0.45 0.46 0.23
183 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
184 INT144238 TNF Positive_regulation of Protein_catabolism of NFKB1 1 0.40 0.35 0.22
185 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
186 INT284139 EDNRB Positive_regulation of Gene_expression of EDNRA 1 0.12 0.45 0.22
187 INT182265 EDN1 Positive_regulation of NOS2 1 0.24 0.56 0.22
188 INT104838 Binding of NFKB1 and IGKV2OR2-1 1 0.01 0 0.22
189 INT182263 EDN1 Positive_regulation of MMP1 1 0.15 0.43 0.21
190 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
191 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
192 INT182258 EDN1 Positive_regulation of Positive_regulation of MMP1 1 0.15 0.47 0.19
193 INT55164 Binding of NFKB1 and WRAP53 1 0.02 0.11 0.19
194 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
195 INT219915 Edn1 Regulation of Positive_regulation of Trpv1 1 0.33 0 0.18
196 INT140096 Gtf3a Positive_regulation of Gene_expression of Edn1 1 0.02 0.44 0.18
197 INT171386 Edn1 Positive_regulation of Mapk1 1 0.05 0.13 0.18
198 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
199 INT284450 Edn1 Positive_regulation of Gene_expression of MMP9 1 0.01 0.3 0.18
200 INT140094 Ifng Regulation of Gene_expression of Edn1 1 0.18 0.44 0.18

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cellular protein metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of cellular protein metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32
2 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
3 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
4 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
5 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19
6 INT116737 Localization of Mif 63 0.81 52.97 28.11
7 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
8 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
9 INT55170 Gene_expression of NFKB1 97 0.77 52.75 23.04
10 INT66208 Positive_regulation of Positive_regulation of NFKB1 45 0.68 20.17 22.62
11 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
12 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
13 INT5048 Binding of Edn1 55 0.47 18.86 19.16
14 INT25517 Regulation of NFKB1 41 0.61 22.28 16.09
15 INT54572 Negative_regulation of Positive_regulation of NFKB1 46 0.58 21.45 15.47
16 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
17 INT9191 Localization of EDN1 94 0.81 57.01 14.78
18 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
19 INT39733 Localization of NFKB1 59 0.79 22.76 13.99
20 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
21 INT6365 Localization of Edn1 56 0.81 18.84 13.83
22 INT55168 Binding of NFKB1 55 0.48 22.94 13.15
23 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
24 INT72949 Binding of Mif 31 0.46 23.12 11.65
25 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
26 INT6361 Localization of Edn1 30 0.81 19.09 9.7
27 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68
28 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
29 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
30 INT10237 Binding of EDN1 40 0.48 16 8.48
31 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
32 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
33 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
34 INT66210 Regulation of Positive_regulation of NFKB1 16 0.60 9.46 7.08
35 INT517 Regulation of Mif 16 0.62 5.43 6.55
36 INT78178 Gene_expression of Ednrb 21 0.75 7.1 6.37
37 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
38 INT119523 Gene_expression of EDNRB 32 0.75 26.47 5.75
39 INT78728 Negative_regulation of Binding of NFKB1 18 0.58 6.89 5.39
40 INT66209 Negative_regulation of Localization of NFKB1 23 0.58 8.2 5.31
41 INT66211 Positive_regulation of Localization of NFKB1 20 0.68 8.18 5.01
42 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
43 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
44 INT29519 Gene_expression of Ednrb 8 0.66 1.99 4.55
45 INT92133 Negative_regulation of Ednrb 8 0.42 1.7 4.44
46 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
47 INT152312 Positive_regulation of Ednrb 7 0.49 1.46 4.04
48 INT56077 Protein_catabolism of NFKB1 16 0.98 8.03 3.94
49 INT56075 Transcription of NFKB1 13 0.71 9.03 3.83
50 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
51 INT79231 Positive_regulation of Gene_expression of NFKB1 18 0.67 9.16 3.66
52 INT134149 Negative_regulation of Gene_expression of NFKB1 7 0.55 4.25 3.63
53 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
54 INT84222 Regulation of Ednrb 4 0.45 2.24 3.25
55 INT139801 Phosphorylation of NFKB1 9 0.66 5.2 3.13
56 INT130226 Positive_regulation of Gene_expression of Mif 4 0.58 15.75 3.03
57 INT53374 Binding of Edn1 17 0.43 11.66 2.98
58 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
59 INT203137 Binding of Mif 6 0.31 9.46 2.71
60 INT128774 Regulation of Gene_expression of Ednrb 3 0.46 1 2.56
61 INT40748 Negative_regulation of Mif 6 0.56 8.33 2.46
62 INT71305 Regulation of Gene_expression of NFKB1 9 0.61 5.41 2.44
63 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
64 INT78177 Negative_regulation of Gene_expression of Ednrb 4 0.41 1.04 2.16
65 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
66 INT103304 Positive_regulation of Mif 6 0.48 8.66 2.05
67 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
68 INT76834 Negative_regulation of Gene_expression of Edn1 4 0.43 1.76 1.88
69 INT178130 Binding of EDNRB 12 0.36 6.18 1.84
70 INT56078 Negative_regulation of Protein_catabolism of NFKB1 7 0.42 4.44 1.83
71 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
72 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
73 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
74 INT76608 Regulation of Negative_regulation of NFKB1 1 0.33 0.53 1.75
75 INT201475 Negative_regulation of Positive_regulation of Ednrb 6 0.42 3.74 1.66
76 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
77 INT165446 Positive_regulation of Phosphorylation of NFKB1 3 0.56 1.88 1.66
78 INT44149 Regulation of Gene_expression of Mif 6 0.54 2.45 1.63
79 INT353326 Negative_regulation of Localization of Mif 1 0.45 1.28 1.59
80 INT139514 Localization of EDNRB 7 0.73 4.63 1.52
81 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
82 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49
83 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
84 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48
85 INT114298 Positive_regulation of Gene_expression of Ednrb 4 0.36 0.79 1.42
86 INT60772 Negative_regulation of Ednrb 8 0.41 4.56 1.39
87 INT66214 Regulation of Binding of NFKB1 2 0.35 0.55 1.28
88 INT253987 Regulation of Localization of Mif 3 0.43 1.65 1.27
89 INT41418 Regulation of Mif 2 0.40 3.86 1.24
90 INT17802 Transcription of Edn1 6 0.24 6.31 1.18
91 INT121368 Transcription of Mif 5 0.72 2.71 1.15
92 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
93 INT102827 Protein_catabolism of Mif 1 0.33 0 1.06
94 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
95 INT78181 Negative_regulation of EDNRB 6 0.57 4.46 0.95
96 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
97 INT69422 Positive_regulation of Negative_regulation of EDN1 2 0.43 0.96 0.95
98 INT49254 Transcription of EDN1 5 0.69 2.42 0.94
99 INT139515 Positive_regulation of EDNRB 15 0.67 10.35 0.93
100 INT152081 Phosphorylation of Edn1 1 0.53 0.39 0.9
101 INT88600 Positive_regulation of Binding of NFKB1 9 0.59 2.1 0.88
102 INT61591 Negative_regulation of Localization of EDN1 11 0.59 2.09 0.85
103 INT57433 Positive_regulation of Binding of EDN1 3 0.49 0.62 0.82
104 INT353328 Regulation of Positive_regulation of Mif 1 0.40 0.89 0.81
105 INT76609 Regulation of Regulation of NFKB1 2 0.20 0.97 0.79
106 INT178127 Positive_regulation of Gene_expression of EDNRB 7 0.51 5.24 0.78
107 INT56073 Positive_regulation of Transcription of NFKB1 4 0.46 1.88 0.77
108 INT61121 Regulation of Regulation of Edn1 1 0.43 0.2 0.75
109 INT2108 Localization of Mif 5 0.77 2.7 0.73
110 INT59970 Positive_regulation of Binding of Edn1 2 0.40 1.11 0.71
111 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69
112 INT49252 Positive_regulation of Localization of EDN1 17 0.69 6.55 0.66
113 INT100396 Transcription of Edn1 7 0.69 2.48 0.66
114 INT32209 Regulation of Gene_expression of Mif 3 0.59 3.41 0.66
115 INT130229 Regulation of Negative_regulation of Mif 1 0.39 1.36 0.66
116 INT353322 Negative_regulation of Positive_regulation of Mif 1 0.38 0.35 0.66
117 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65
118 INT44148 Negative_regulation of Gene_expression of Mif 6 0.41 0.95 0.64
119 INT56074 Negative_regulation of Transcription of NFKB1 3 0.58 1.53 0.64
120 INT139513 Negative_regulation of Localization of EDNRB 2 0.41 0 0.62
121 INT114299 Transcription of Ednrb 2 0.19 0.32 0.59
122 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57
123 INT135715 Negative_regulation of Localization of Edn1 5 0.42 1.7 0.56
124 INT63910 Regulation of Positive_regulation of Edn1 2 0.43 0.64 0.54
125 INT107106 Positive_regulation of Negative_regulation of NFKB1 1 0.33 1.26 0.54
126 INT131641 Negative_regulation of Negative_regulation of Edn1 1 0.37 0.31 0.52
127 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51
128 INT337079 Negative_regulation of Gene_expression of Mif 1 0.41 4.17 0.51
129 INT55372 Regulation of Localization of Edn1 2 0.38 0.64 0.46
130 INT201478 Regulation of Positive_regulation of Ednrb 1 0.35 0.68 0.44
131 INT57434 Regulation of Regulation of EDN1 1 0.40 0.47 0.44
132 INT131106 Positive_regulation of Positive_regulation of Ednrb 1 0.15 0.91 0.4
133 INT81433 Negative_regulation of Positive_regulation of Edn1 4 0.39 0.81 0.38
134 INT166794 Regulation of Localization of NFKB1 2 0.36 0.49 0.38
135 INT166795 Regulation of Phosphorylation of NFKB1 1 0.36 0.49 0.38
136 INT116735 Positive_regulation of Positive_regulation of Mif 1 0.70 0.61 0.38
137 INT201476 Positive_regulation of Negative_regulation of Ednrb 1 0.49 0.62 0.36
138 INT113368 Regulation of Negative_regulation of Edn1 1 0.45 0.71 0.35
139 INT141013 Regulation of Gene_expression of Edn1 2 0.24 0.55 0.34
140 INT253977 Positive_regulation of Binding of Mif 1 0.48 0.97 0.32
141 INT16368 Protein_catabolism of Edn1 2 0.72 0.18 0.31
142 INT350971 Negative_regulation of Binding of EDNRB 1 0.13 0.86 0.29
143 INT139512 Positive_regulation of Localization of EDNRB 3 0.37 0.69 0.26
144 INT84038 Protein_catabolism of Edn1 2 0.86 0.69 0.26
145 INT121366 Regulation of Transcription of Mif 1 0.02 0.61 0.24
146 INT121367 Negative_regulation of Transcription of Mif 1 0.02 0.59 0.24
147 INT337077 Positive_regulation of Localization of Mif 1 0.58 0.96 0.21
148 INT67265 Positive_regulation of Negative_regulation of Edn1 1 0.61 0.05 0.21
149 INT143955 Negative_regulation of Negative_regulation of NFKB1 1 0.35 0.48 0.2
150 INT156920 Phosphorylation of EDN1 4 0.61 0.66 0.19
151 INT53372 Positive_regulation of Regulation of Edn1 1 0.50 0 0.19
152 INT100397 Regulation of Transcription of Edn1 1 0.00 0.1 0.19
153 INT55013 Localization of Ednrb 2 0.16 0.98 0.18
154 INT274098 Regulation of EDNRB 1 0.33 2.41 0.18
155 INT242342 Regulation of Ednrb 1 0.09 2.03 0.15
156 INT256229 Protein_catabolism of EDNRB 3 0.64 0.96 0.14
157 INT284152 Regulation of Transcription of EDN1 1 0.32 0.44 0.13
158 INT6362 Negative_regulation of Localization of Edn1 3 0.16 1.92 0.12
159 INT337076 Positive_regulation of Negative_regulation of Mif 1 0.48 1.44 0.12
160 INT15391 Negative_regulation of Positive_regulation of Edn1 2 0.07 0.1 0.1
161 INT170744 Positive_regulation of Transcription of Edn1 2 0.20 1.3 0.1
162 INT49257 Positive_regulation of Transcription of EDN1 2 0.46 1.1 0.08
163 INT126441 Negative_regulation of Transcription of Edn1 1 0.40 0.17 0.08
164 INT324892 Binding of Ednrb 1 0.06 0.32 0.06
165 INT174340 Protein_catabolism of Mif 1 0.89 0.09 0.04
166 INT264273 Localization of Ednrb 1 0.01 0 0.03
167 INT353329 Positive_regulation of Regulation of Mif 1 0.36 0 0
168 INT280682 Positive_regulation of Transcription of Edn1 1 0.34 0 0
169 INT49261 Negative_regulation of Protein_catabolism of EDN1 1 0.58 0 0
170 INT337082 Phosphorylation of Mif 1 0.68 0.97 0
171 INT284148 Positive_regulation of Positive_regulation of EDNRB 1 0.29 0.54 0
172 INT181578 Negative_regulation of Phosphorylation of Edn1 1 0.37 0.1 0
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