GO:0032320

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Name positive regulation of Ras GTPase activity
Categary Process
Go Slim No
Go Link GO:0032320
Unique Molecular Interactions 285
Total Molecular Interactions 441
Total Single Events 2387
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of Ras GTPase activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of Ras GTPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
2 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
3 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
4 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
5 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
6 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
7 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
8 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
9 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
10 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
11 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
12 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
13 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
14 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
15 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
16 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2
17 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
18 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
19 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
20 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
21 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
22 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
23 INT93614 Ngf Positive_regulation of Ntrk1 2 0.52 0.85 1.05
24 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
25 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
26 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
27 INT127672 Binding of NGFR and NTRK1 1 0.17 2.28 0.97
28 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
29 INT127673 NGF Regulation of Gene_expression of NTRK1 1 0.48 2.12 0.92
30 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
31 INT297463 Binding of Ntrk1 and Ngf 1 0.10 0.78 0.87
32 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
33 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
34 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83
35 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
36 INT78714 Ntrk1 Positive_regulation of Ngf 2 0.50 0.63 0.78
37 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78
38 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72
39 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
40 INT351376 Mir470 Negative_regulation of Ntrk1 1 0.01 1.54 0.7
41 INT118979 NGF Positive_regulation of Phosphorylation of NTRK1 1 0.56 0.67 0.67
42 INT114843 NTRK1 Regulation of Gene_expression of Lgals1 1 0.06 0.84 0.66
43 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
44 INT221847 Binding of Calca and Ntrk1 1 0.03 0.9 0.65
45 INT74395 Htr2b Negative_regulation of Pdyn 1 0.03 0 0.61
46 INT79747 Ntf3 Regulation of Positive_regulation of Ntrk1 1 0.35 0 0.6
47 INT142990 Serpinc1 Positive_regulation of Phosphorylation of S1pr1 1 0.03 0.05 0.59
48 INT144864 Htr2b Positive_regulation of Localization of Gh1 1 0.48 0 0.58
49 INT164457 Ngf Positive_regulation of NTRK1 1 0.15 0.57 0.58
50 INT164458 Negative_regulation of Ngf Positive_regulation of NTRK1 1 0.14 0.57 0.58
51 INT98035 Binding of Ntrk1 and Trpv1 1 0.54 0.41 0.57
52 INT242602 Binding of Ntf3 and Ntrk1 1 0.10 0.14 0.57
53 INT164973 Binding of RASA1 and Rgs7 1 0.00 0 0.54
54 INT164972 Binding of RASA1 and Rgs8 1 0.00 0 0.53
55 INT69343 Binding of NTRK1 and Igh-6 1 0.02 0.69 0.53
56 INT245553 Runx1 Positive_regulation of Gene_expression of Ntrk1 2 0.45 1.41 0.52
57 INT242631 Binding of Gfra2 and Ntrk1 1 0.01 0 0.52
58 INT256040 Ngf Regulation of Gene_expression of Ntrk1 1 0.36 0.73 0.5
59 INT242634 Binding of Gfra1 and Ntrk1 1 0.02 0 0.46
60 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
61 INT256042 Negative_regulation of Musk Negative_regulation of Ntrk1 1 0.08 0.48 0.44
62 INT226341 S1PR1 Regulation of MBTPS1 1 0.00 0.76 0.44
63 INT298284 Runx3 Negative_regulation of Gene_expression of Ntrk1 1 0.26 0.39 0.43
64 INT298263 Pou4f1 Regulation of Gene_expression of Ntrk1 1 0.34 0.61 0.43
65 INT127675 NGF Regulation of NTRK1 1 0.48 1.01 0.42
66 INT346222 Positive_regulation of Braf Positive_regulation of Map2k1 1 0.15 0.67 0.39
67 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
68 INT298266 Gene_expression of Runx1 Positive_regulation of Ntrk1 1 0.28 0.34 0.39
69 INT226381 S1PR1 Positive_regulation of Gene_expression of IK 1 0.00 0.64 0.38
70 INT166247 Ngf Regulation of Ntrk1 1 0.05 0.09 0.38
71 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
72 INT148241 Binding of Kit and Ntrk1 1 0.25 0.44 0.35
73 INT356366 S1pr1 Regulation of Gopc 1 0.19 1.22 0.33
74 INT135891 S1pr1 Regulation of Prps1 1 0.01 0.15 0.33
75 INT124475 MAP2K1 Positive_regulation of Positive_regulation of CPOX 1 0.04 0.68 0.33
76 INT302842 Binding of S1PR1 and S1pr1 1 0.24 0.92 0.32
77 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32
78 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
79 INT129022 Ngf Positive_regulation of Phosphorylation of Ntrk1 1 0.39 0.37 0.31
80 INT156151 POU4F1 Positive_regulation of Gene_expression of NTRK1 1 0.46 0.37 0.31
81 INT156163 POU4F1 Positive_regulation of NTRK1 1 0.46 0.37 0.31
82 INT156158 CREBZF Positive_regulation of Gene_expression of NTRK1 1 0.42 0.37 0.31
83 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3
84 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
85 INT156159 CREBZF Positive_regulation of NTRK1 1 0.63 0.36 0.3
86 INT242622 Binding of Bdnf and Ntrk1 1 0.05 0.07 0.29
87 INT245554 Tbx15 Positive_regulation of Gene_expression of Ntrk1 1 0.02 0.65 0.29
88 INT156152 POU4F1 Positive_regulation of Positive_regulation of NTRK1 1 0.31 0.38 0.29
89 INT118652 Positive_regulation of Bdnf Positive_regulation of Ntrk1 1 0.31 0.24 0.29
90 INT118654 Bdnf Positive_regulation of Ntrk1 1 0.43 0.24 0.28
91 INT156160 TFAM Regulation of Gene_expression of NTRK1 1 0.03 0.39 0.27
92 INT156150 POU4F1 Regulation of Gene_expression of NTRK1 1 0.18 0.39 0.27
93 INT159656 Binding of BDNF and NTRK1 1 0.26 0.34 0.26
94 INT245567 Tbx15 Positive_regulation of Ntrk1 1 0.02 0.9 0.24
95 INT302819 Regulation of S1pr1 Positive_regulation of Ptger2 1 0.02 0.35 0.22
96 INT298876 RAB7A Positive_regulation of Protein_catabolism of NTRK1 1 0.14 0.44 0.22
97 INT346224 Braf Negative_regulation of Phosphorylation of Map2k1 1 0.14 0.62 0.22
98 INT254687 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Mmp13 1 0.06 0.2 0.2
99 INT302835 S1pr1 Positive_regulation of Ptger2 1 0.03 0.3 0.2
100 INT280473 Binding of Ntrk1 and Ntf4 1 0.00 0.13 0.2
101 INT223477 Binding of Ntrk1 and Ntrk3 2 0.16 0.3 0.19
102 INT345172 Lpar1 Positive_regulation of S1pr1 1 0.21 0.19 0.19
103 INT254683 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Plaur 1 0.01 0.07 0.18
104 INT254698 Gopc Positive_regulation of Positive_regulation of Map2k1 1 0.06 0.07 0.18
105 INT302846 Negative_regulation of Binding of S1PR1 and S1pr1 1 0.28 0.41 0.18
106 INT159658 Positive_regulation of Binding of NGF and NTRK1 1 0.35 0.09 0.18
107 INT103197 Nf1 Negative_regulation of ras 1 0.04 1.19 0.17
108 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
109 INT191621 Binding of Drd3 and Nf1 1 0.32 0.53 0.17
110 INT304537 Map2k1 Positive_regulation of PRKG1 1 0.01 0.66 0.16
111 INT298256 Runx1 Positive_regulation of Negative_regulation of Ntrk1 1 0.30 0.55 0.16
112 INT304503 Map2k1 Positive_regulation of Nos1 1 0.07 0.66 0.16
113 INT103198 NF1 Negative_regulation of ras 1 0.05 1.19 0.16
114 INT349861 Gfra1 Negative_regulation of Ntrk1 1 0.01 0.36 0.15
115 INT349852 Gfra2 Negative_regulation of Ntrk1 1 0.27 0.3 0.15
116 INT245566 Runx1 Negative_regulation of Ntrk1 1 0.39 0.65 0.15
117 INT349859 Gfra2 Negative_regulation of Ntrk1 1 0.02 0.3 0.15
118 INT349862 Gfra3 Negative_regulation of Ntrk1 1 0.02 0.3 0.15
119 INT201728 Ntrk1 Regulation of Transcription of App 1 0.03 0.39 0.15
120 INT349856 Gfra3 Negative_regulation of Ntrk1 1 0.23 0.3 0.15
121 INT349854 Gfra1 Negative_regulation of Ntrk1 1 0.12 0.36 0.15
122 INT302844 Positive_regulation of Binding of S1PR1 and S1pr1 1 0.32 0.52 0.15
123 INT223475 Binding of Ntrk1 and Ntrk2 2 0.22 0.25 0.14
124 INT151925 Bdnf Negative_regulation of Ntrk1 1 0.10 0 0.14
125 INT304824 Binding of Rasa1 and Tnnc1 1 0.01 0 0.13
126 INT352073 Positive_regulation of Binding of ADAM11 and CCL19 1 0.22 1.27 0.13
127 INT352080 Binding of ADAM11 and CCL19 1 0.16 1.27 0.13
128 INT153620 Binding of Ntrk1 and WNK1 1 0.02 0.85 0.12
129 INT191612 Nf1 Positive_regulation of ras 1 0.25 2.6 0.11
130 INT280893 Gene_expression of Runx1 Positive_regulation of Gene_expression of Ntrk1 1 0.33 0.44 0.1
131 INT280492 Ntrk1 Regulation of Protein_catabolism of BDNF 1 0.03 0.14 0.1
132 INT304499 Map2k1 Positive_regulation of Mapk1 1 0.12 0.8 0.1
133 INT122927 Ntrk1 Positive_regulation of SPTLC1 1 0.00 0.65 0.09
134 INT224531 Positive_regulation of Map2k1 Positive_regulation of Positive_regulation of Ankh 1 0.07 0.54 0.09
135 INT191617 Binding of Nf1 and Rtcd1 1 0.01 0.95 0.08
136 INT137632 Rasa1 Regulation of Ednrb 1 0.05 0 0.08
137 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
138 INT233519 Binding of S1pr1 and S1pr2 1 0.13 0.2 0.08
139 INT345178 S1pr1 Positive_regulation of Lpar1 1 0.14 0.09 0.07
140 INT345160 S1pr1 Positive_regulation of P2ry10 1 0.11 0.09 0.07
141 INT280894 Runx1 Positive_regulation of Transcription of Ntrk1 1 0.38 0.36 0.07
142 INT263743 Rasgrf1 Positive_regulation of Positive_regulation of Mapk1 1 0.11 0 0.06
143 INT263770 Rasgrf1 Positive_regulation of Positive_regulation of Grin1 1 0.24 0 0.06
144 INT263727 Binding of Grin2b and Rasgrf1 1 0.18 0 0.05
145 INT263730 Binding of Grin2a and Rasgrf1 1 0.23 0 0.05
146 INT194699 MAP2K1 Positive_regulation of MAPK8 1 0.05 0 0.04
147 INT194703 MAP2K1 Positive_regulation of MAP2K6 1 0.21 0 0.04
148 INT194677 Binding of GADD45A and MAP2K1 1 0.27 0 0.04
149 INT194719 MAP2K1 Positive_regulation of MAPK1 1 0.27 0 0.04
150 INT194701 MAP2K1 Positive_regulation of MAP2K4 1 0.21 0 0.04
151 INT194732 MAP2K1 Positive_regulation of Gene_expression of MAPK1 1 0.27 0 0.04
152 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 0.11 2.26 0.04
153 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04
154 INT194691 MAP2K1 Positive_regulation of MAP2K3 1 0.23 0 0.04
155 INT295479 PRKCA Positive_regulation of MAP2K1 1 0.14 0.35 0.03
156 INT345147 Binding of S1pr1 and Gpbar1 1 0.03 0.07 0.03
157 INT345167 Binding of S1pr1 and Lpar1 1 0.13 0.07 0.03
158 INT269502 Lta Negative_regulation of Map2k1 1 0.17 0.48 0.03
159 INT352074 ADAM11 Positive_regulation of Gene_expression of CCL19 1 0.17 0.74 0.03
160 INT295474 IRF6 Positive_regulation of MAP2K1 1 0.18 0.41 0.03
161 INT191613 Binding of Nf1 and Rasa1 1 0.06 0.88 0.03
162 INT298873 RAB7A Regulation of Protein_catabolism of NTRK1 1 0.12 0.25 0.03
163 INT121225 Positive_regulation of Ngf Positive_regulation of Ntrk1 2 0.49 0 0
164 INT258203 S1PR1 Positive_regulation of GTPBP4 1 0.00 0.29 0
165 INT300874 Ngf Positive_regulation of NTRK1 1 0.07 0 0
166 INT254689 Gene_expression of Map2k2 Positive_regulation of Map2k1 1 0.30 0.4 0
167 INT291753 ALDOA Positive_regulation of ALDH1A1 1 0.00 0 0
168 INT225892 Binding of GAB1 and RASA1 1 0.01 0.06 0
169 INT254707 Positive_regulation of Map2k1 Regulation of Gene_expression of BAK1 1 0.05 0.67 0
170 INT254692 Positive_regulation of Map2k1 Regulation of Gene_expression of Mdk 1 0.05 0.42 0
171 INT321180 Ntrk2 Regulation of Ntrk1 1 0.16 0 0
172 INT258207 S1PR1 Positive_regulation of Phosphorylation of IFI44 1 0.13 0 0
173 INT331235 RASA1 Positive_regulation of Mtor 1 0.00 0.32 0
174 INT258206 S1PR1 Positive_regulation of Phosphorylation of MAPK1 1 0.12 0 0
175 INT271966 Phosphorylation of Rasa1 Positive_regulation of Tsc2 1 0.01 0.31 0
176 INT254693 Gene_expression of Map2k1 Regulation of Map2k2 1 0.29 0.78 0
177 INT254686 Gene_expression of Map2k1 Regulation of Gene_expression of Mdk 1 0.08 0.42 0
178 INT254703 Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 0.91 0
179 INT254696 Map2k2 Regulation of Map2k1 1 0.18 0.78 0
180 INT213015 Binding of S1pr1 and S1pr3 1 0.16 1.17 0
181 INT254706 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
182 INT124074 Binding of Ntrk1 and Ugt1a10 1 0.06 0 0
183 INT254704 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 1.43 0
184 INT293795 Binding of RASA1 and ras 1 0.00 0.08 0
185 INT254702 Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
186 INT300873 Positive_regulation of Ngf Positive_regulation of NTRK1 1 0.07 0 0
187 INT206843 Binding of ALDH1A1 and ESR1 1 0.07 0 0
188 INT331229 Rasa1 Positive_regulation of Mtor 1 0.00 0.32 0
189 INT254684 Map2k2 Positive_regulation of Map2k1 1 0.45 0.4 0
190 INT331233 Binding of Mtor and Rasa1 1 0.00 0.32 0
191 INT331236 Binding of RASA1 and Mtor 1 0.00 0.32 0
192 INT223478 Binding of Ntrk1 and Dok5 1 0.18 0.17 0
193 INT180836 Binding of CTD and NF1 1 0.15 0.2 0
194 INT336606 Binding of Mapk8 and Map2k1 1 0.09 0.72 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of Ras GTPase activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of Ras GTPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
2 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
3 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24
4 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
5 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
6 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09
7 INT66041 Positive_regulation of NTRK1 24 0.70 16.12 8.42
8 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
9 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
10 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
11 INT50973 Negative_regulation of Gene_expression of Ntrk1 22 0.56 11.12 7.38
12 INT116163 Gene_expression of S1pr1 29 0.78 14.11 7.27
13 INT93137 Negative_regulation of Map2k1 17 0.42 4.51 6.49
14 INT129020 Phosphorylation of Ntrk1 17 0.80 5.97 6.37
15 INT79737 Positive_regulation of Ntrk1 12 0.49 3.98 6.24
16 INT71151 Regulation of NTRK1 10 0.62 6.65 6.21
17 INT48313 Binding of NTRK1 19 0.47 14.44 6.12
18 INT71152 Negative_regulation of NTRK1 15 0.59 10.28 5.5
19 INT135440 Positive_regulation of Phosphorylation of Map2k1 5 0.49 1.32 5.22
20 INT68216 Binding of NF1 40 0.48 51.24 4.59
21 INT78981 Regulation of Ntrk1 6 0.44 3.89 4.52
22 INT81750 Regulation of Ntrk1 13 0.52 6.03 4.37
23 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2
24 INT79736 Negative_regulation of Ntrk1 11 0.57 2.31 4.14
25 INT106065 Negative_regulation of MAP2K1 27 0.57 12.69 3.97
26 INT28983 Regulation of Htr2b 3 0.22 0.26 3.96
27 INT142984 Positive_regulation of S1pr1 13 0.70 7.9 3.84
28 INT56768 Positive_regulation of Gene_expression of Ntrk1 5 0.67 3.91 3.83
29 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
30 INT83411 Binding of Ntrk1 6 0.19 3.7 3.74
31 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
32 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02
33 INT93109 Phosphorylation of NTRK1 5 0.80 3.22 2.99
34 INT156189 Positive_regulation of Gene_expression of Ntrk1 11 0.49 2.81 2.89
35 INT62610 Phosphorylation of Ntrk1 5 0.56 1.64 2.68
36 INT119518 Positive_regulation of Gene_expression of NTRK1 5 0.67 3.47 2.66
37 INT17993 Negative_regulation of RASA1 8 0.41 7.34 2.62
38 INT116164 Positive_regulation of Gene_expression of S1pr1 5 0.66 4.72 2.42
39 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
40 INT64700 Binding of Nf1 14 0.45 15.24 2.29
41 INT144580 Regulation of S1pr1 1 0.44 0.32 2.1
42 INT127756 Negative_regulation of Map2k1 10 0.41 6.69 2.04
43 INT43900 Gene_expression of RASA1 13 0.58 12 2.03
44 INT66941 Localization of NTRK1 8 0.78 5.89 1.96
45 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93
46 INT68181 Binding of Nf1 6 0.48 8.14 1.88
47 INT107477 Positive_regulation of Phosphorylation of Ntrk1 3 0.30 0.88 1.86
48 INT223447 Regulation of Gene_expression of Ntrk1 7 0.34 1.29 1.82
49 INT108486 Positive_regulation of Gene_expression of CCL19 2 0.45 6.2 1.79
50 INT144581 Gene_expression of S1pr1 4 0.77 1.64 1.77
51 INT135444 Regulation of Map2k1 4 0.44 1.15 1.77
52 INT230668 Gene_expression of Rasa1 9 0.68 3.25 1.74
53 INT85046 Positive_regulation of Positive_regulation of NTRK1 2 0.50 0.63 1.51
54 INT14916 Binding of RASA1 15 0.37 13.64 1.44
55 INT129017 Negative_regulation of Phosphorylation of Ntrk1 3 0.41 1.5 1.42
56 INT104121 Positive_regulation of MAP2K1 8 0.61 4.84 1.41
57 INT167952 Regulation of S1pr1 5 0.26 2.96 1.4
58 INT175525 Positive_regulation of Phosphorylation of Map2k1 8 0.33 7.02 1.37
59 INT71782 Gene_expression of MAP2K1 7 0.68 3.17 1.37
60 INT245532 Negative_regulation of Positive_regulation of Ntrk1 2 0.34 1.56 1.34
61 INT108601 Negative_regulation of Gene_expression of NTRK1 2 0.41 0.28 1.31
62 INT85047 Positive_regulation of Negative_regulation of NTRK1 3 0.47 2.13 1.3
63 INT93612 Transcription of Ntrk1 2 0.52 1.31 1.26
64 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24
65 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23
66 INT152010 Positive_regulation of Ccr7 3 0.47 1.46 1.15
67 INT93610 Negative_regulation of Gene_expression of Ntrk1 2 0.41 0.84 1.15
68 INT226466 Gene_expression of S1PR1 2 0.56 4.51 1.14
69 INT124069 Localization of Ntrk1 9 0.59 3.32 1.13
70 INT211723 Binding of Rasa1 3 0.07 0.85 1.03
71 INT138287 Gene_expression of Map2k1 69 0.65 46.14 1.02
72 INT181354 Binding of Ccr7 2 0.23 1.94 1.01
73 INT142989 Negative_regulation of S1pr1 2 0.43 0.72 0.99
74 INT30157 Gene_expression of Htr2b 2 0.48 0 0.94
75 INT201635 Positive_regulation of Positive_regulation of Ntrk1 3 0.40 1.15 0.85
76 INT71778 Positive_regulation of Gene_expression of MAP2K1 2 0.36 0.37 0.81
77 INT343139 Transcription of S1pr1 1 0.67 0.74 0.77
78 INT304823 Negative_regulation of Rasa1 6 0.10 0.39 0.76
79 INT211909 Regulation of Positive_regulation of Map2k1 1 0.21 0.47 0.76
80 INT258247 Positive_regulation of S1PR1 1 0.50 0.65 0.73
81 INT93609 Positive_regulation of Transcription of Ntrk1 1 0.45 0.86 0.69
82 INT62608 Negative_regulation of Phosphorylation of Ntrk1 1 0.40 0.24 0.69
83 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68
84 INT179133 Localization of Nf1 2 0.80 2.18 0.68
85 INT49650 Gene_expression of Nf1 4 0.76 3.38 0.67
86 INT233464 Binding of S1pr1 2 0.28 1.81 0.66
87 INT118981 Positive_regulation of Phosphorylation of NTRK1 1 0.49 0.66 0.66
88 INT142986 Phosphorylation of S1pr1 2 0.43 1.62 0.64
89 INT85049 Negative_regulation of Positive_regulation of NTRK1 1 0.59 0.56 0.64
90 INT57127 Binding of Htr2b 2 0.36 0.05 0.63
91 INT93613 Regulation of Gene_expression of Ntrk1 1 0.60 0.8 0.59
92 INT116165 Localization of S1pr1 4 0.80 2.2 0.58
93 INT118730 Regulation of Transcription of Ntrk1 1 0.43 0.45 0.57
94 INT90416 Positive_regulation of RASA1 3 0.67 1.58 0.56
95 INT298887 Protein_catabolism of NTRK1 1 0.25 1.1 0.56
96 INT142982 Negative_regulation of Gene_expression of S1pr1 1 0.23 0 0.56
97 INT213000 Binding of S1PR1 9 0.47 2.33 0.54
98 INT104120 Positive_regulation of Positive_regulation of MAP2K1 1 0.49 0 0.54
99 INT135887 Localization of S1pr1 1 0.80 0.52 0.52
100 INT61992 Positive_regulation of Gene_expression of NF1 3 0.50 4.47 0.51
101 INT236915 Binding of Map2k1 2 0.15 1.51 0.49
102 INT7248 Localization of RASA1 4 0.61 2.52 0.47
103 INT354384 Regulation of CCL19 1 0.23 1.89 0.47
104 INT316933 Transcription of Nf1 1 0.18 0.49 0.47
105 INT316939 Positive_regulation of Transcription of Nf1 1 0.16 0.49 0.47
106 INT167953 Positive_regulation of Regulation of S1pr1 1 0.42 0.83 0.46
107 INT206880 Gene_expression of ALDH1A1 5 0.45 5.02 0.45
108 INT97723 Negative_regulation of Regulation of Ntrk1 1 0.37 0.52 0.45
109 INT55893 Gene_expression of Rasa1 5 0.52 1.04 0.44
110 INT247798 Negative_regulation of Rasa1 3 0.09 1.05 0.44
111 INT181358 Transcription of Ccr7 1 0.43 1.33 0.43
112 INT230653 Phosphorylation of Rasa1 3 0.55 0.6 0.42
113 INT297454 Negative_regulation of Negative_regulation of Ntrk1 1 0.09 0.23 0.41
114 INT76874 Negative_regulation of Htr2b 1 0.07 0 0.41
115 INT138282 Positive_regulation of Gene_expression of Map2k1 13 0.49 7.46 0.39
116 INT142987 Negative_regulation of Positive_regulation of S1pr1 1 0.31 0.19 0.39
117 INT242553 Positive_regulation of Negative_regulation of Ntrk1 1 0.21 0 0.39
118 INT304528 Gene_expression of Map2k1 3 0.58 1.76 0.37
119 INT129343 Positive_regulation of Rasa1 2 0.10 1.03 0.37
120 INT71153 Regulation of Negative_regulation of NTRK1 1 0.27 0.29 0.37
121 INT112334 Regulation of NF1 18 0.52 15.85 0.34
122 INT148814 Localization of Ntrk1 1 0.78 0.16 0.34
123 INT84923 Transcription of NTRK1 2 0.67 1.65 0.33
124 INT304526 Binding of Map2k1 1 0.11 0.6 0.32
125 INT240205 Regulation of MAP2K1 3 0.26 0.44 0.28
126 INT55894 Positive_regulation of Gene_expression of Rasa1 1 0.47 0.19 0.28
127 INT244625 Negative_regulation of Localization of Ntrk1 1 0.04 0.56 0.28
128 INT156165 Regulation of Gene_expression of NTRK1 2 0.37 1.91 0.27
129 INT305840 Positive_regulation of Gene_expression of Ccr7 1 0.27 0.25 0.24
130 INT57126 Transcription of Htr2b 1 0.33 0 0.24
131 INT175506 Regulation of Positive_regulation of Map2k1 2 0.32 1.58 0.23
132 INT129342 Positive_regulation of Positive_regulation of Nf1 1 0.50 0.79 0.23
133 INT68180 Regulation of Nf1 2 0.27 2.02 0.22
134 INT298922 Negative_regulation of Protein_catabolism of NTRK1 1 0.11 0.44 0.22
135 INT304519 Positive_regulation of Gene_expression of Map2k1 1 0.15 0.41 0.22
136 INT280460 Positive_regulation of Localization of Ntrk1 2 0.11 0.32 0.21
137 INT258243 Regulation of Gene_expression of S1PR1 1 0.32 0 0.21
138 INT258232 Positive_regulation of Gene_expression of S1PR1 1 0.50 0.61 0.21
139 INT177938 Negative_regulation of NF1 9 0.43 10.3 0.2
140 INT129341 Negative_regulation of Gene_expression of Nf1 2 0.43 1.67 0.2
141 INT220167 Localization of Ccr7 1 0.31 0.39 0.18
142 INT242558 Transcription of Ntrk1 2 0.37 0.66 0.17
143 INT155285 Positive_regulation of Nf1 1 0.16 0.55 0.17
144 INT201013 Regulation of Gene_expression of RASA1 1 0.05 0.16 0.16
145 INT103196 Negative_regulation of Gene_expression of Nf1 1 0.57 1.21 0.16
146 INT55892 Negative_regulation of Gene_expression of Rasa1 1 0.29 0.1 0.15
147 INT302794 Negative_regulation of Binding of S1pr1 1 0.25 0.34 0.15
148 INT302812 Positive_regulation of Binding of S1PR1 1 0.45 0.52 0.15
149 INT254671 Regulation of Map2k1 5 0.43 1.83 0.14
150 INT265533 Negative_regulation of Phosphorylation of Map2k1 1 0.41 0 0.14
151 INT304822 Regulation of Negative_regulation of Rasa1 1 0.05 0 0.14
152 INT175527 Localization of Map2k1 4 0.31 2.41 0.13
153 INT258223 Negative_regulation of Binding of S1PR1 1 0.31 0 0.13
154 INT304820 Transcription of Rasa1 1 0.10 0 0.12
155 INT201009 Transcription of RASA1 1 0.07 0.14 0.12
156 INT254673 Positive_regulation of Positive_regulation of Map2k1 3 0.35 1.65 0.11
157 INT349974 Positive_regulation of Rasa1 1 0.04 0.92 0.11
158 INT302783 Positive_regulation of Localization of S1pr1 1 0.29 0.42 0.1
159 INT302805 Regulation of Localization of S1pr1 1 0.26 0.42 0.1
160 INT242544 Positive_regulation of Transcription of Ntrk1 1 0.29 0.3 0.1
161 INT61991 Negative_regulation of Gene_expression of NF1 1 0.59 1.67 0.08
162 INT215418 Positive_regulation of Phosphorylation of MAP2K1 1 0.03 0.51 0.08
163 INT238567 Gene_expression of Syngap1 1 0.47 0.15 0.08
164 INT215420 Phosphorylation of MAP2K1 1 0.05 0.51 0.08
165 INT190026 Positive_regulation of Gene_expression of Nf1 3 0.53 2.45 0.07
166 INT298923 Positive_regulation of Protein_catabolism of NTRK1 1 0.13 0.5 0.07
167 INT302795 Regulation of Binding of S1pr1 1 0.26 0.36 0.07
168 INT352112 Transcription of CCL19 1 0.38 1.37 0.06
169 INT352100 Positive_regulation of Transcription of CCL19 1 0.37 1.38 0.06
170 INT247808 Negative_regulation of Localization of Rasa1 1 0.06 0.96 0.04
171 INT247815 Localization of Rasa1 1 0.10 1.69 0.04
172 INT281764 Negative_regulation of Gene_expression of Map2k1 1 0.18 1.11 0.04
173 INT206879 Positive_regulation of Gene_expression of ALDH1A1 1 0.25 1.32 0.03
174 INT352095 Regulation of Gene_expression of CCL19 1 0.21 0.68 0.03
175 INT206871 Regulation of Gene_expression of ALDH1A1 1 0.23 1.32 0.03
176 INT206873 Negative_regulation of Gene_expression of ALDH1A1 1 0.34 1.3 0.03
177 INT169558 Positive_regulation of NF1 13 0.59 13.58 0
178 INT258231 Phosphorylation of S1PR1 2 0.45 0.95 0
179 INT112333 Localization of NF1 2 0.51 0.63 0
180 INT216268 Positive_regulation of Positive_regulation of NF1 2 0.40 2.08 0
181 INT329571 Binding of MAP2K1 2 0.11 0.4 0
182 INT225851 Phosphorylation of RASA1 2 0.05 0.14 0
183 INT155405 Negative_regulation of Positive_regulation of Ntrk1 1 0.09 0.15 0
184 INT230655 Regulation of Gene_expression of Rasa1 1 0.54 0.26 0
185 INT294168 Regulation of Gene_expression of S1pr1 1 0.00 0.2 0
186 INT84922 Positive_regulation of Transcription of NTRK1 1 0.41 0.16 0
187 INT352113 Positive_regulation of Positive_regulation of CCL19 1 0.27 1.06 0
188 INT351372 Regulation of Localization of Ntrk1 1 0.34 0.92 0
189 INT281758 Positive_regulation of Protein_catabolism of Map2k1 1 0.29 0.13 0
190 INT247790 Regulation of Rasa1 1 0.05 1.44 0
191 INT258241 Transcription of S1PR1 1 0.38 0.13 0
192 INT230656 Positive_regulation of Gene_expression of Rasa1 1 0.61 0.24 0
193 INT281756 Protein_catabolism of Map2k1 1 0.42 0.13 0
194 INT270350 Positive_regulation of S1pr1 1 0.32 0.98 0
195 INT291974 Regulation of RASA1 1 0.03 0.29 0
196 INT346853 Binding of Rasa1 1 0.09 1.24 0
197 INT175533 Regulation of Gene_expression of Map2k1 1 0.20 1.55 0
198 INT286141 Negative_regulation of Negative_regulation of NF1 1 0.01 0.66 0
199 INT237279 Regulation of Binding of NF1 1 0.38 0.79 0
200 INT258245 Regulation of S1PR1 1 0.44 0.55 0
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