GO:0032355

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Name response to estradiol stimulus
Categary Process
Go Slim No
Go Link GO:0032355
Unique Molecular Interactions 3461
Total Molecular Interactions 4904
Total Single Events 55576
Pain Genes Associated 148

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to estradiol stimulus. They are ordered first by their pain relevance and then by number of times they were reported for response to estradiol stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
2 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
3 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18
4 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
5 INT31439 Penk Positive_regulation of Localization of Prl 8 0.55 0.23 6.24
6 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
7 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44
8 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96
9 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
10 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
11 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
12 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
13 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39
14 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29
15 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19
16 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
17 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
18 INT31440 Penk Positive_regulation of Prl 7 0.76 0 4.1
19 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
20 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
21 INT2169 Penk Regulation of Localization of Prl 6 0.48 0 4.03
22 INT107801 Ugt1a5 Positive_regulation of Localization of Prl 3 0.76 1 3.9
23 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
24 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
25 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
26 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
27 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
28 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
29 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
30 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
31 INT3434 Vip Positive_regulation of Localization of Prl 6 0.76 0.16 3.21
32 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2
33 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
34 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
35 INT40660 Pdyn Positive_regulation of Localization of Prl 1 0.27 0 3.01
36 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
37 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
38 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
39 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
40 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
41 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
42 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
43 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
44 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
45 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
46 INT314141 Binding of Tacr3 and SFTPA1 1 0.00 3.02 2.48
47 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
48 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
49 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
50 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
51 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25
52 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
53 INT91860 Npy Regulation of Npy1r 2 0.28 1.13 2.24
54 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
55 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
56 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
57 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
58 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18
59 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
60 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
61 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
62 INT3576 Sst Negative_regulation of Localization of Gh1 6 0.23 0 2.13
63 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
64 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
65 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
66 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
67 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
68 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
69 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
70 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
71 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
72 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
73 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
74 INT40238 Penk Regulation of Oxt 1 0.04 0 1.83
75 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82
76 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
77 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
78 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
79 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
80 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
81 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
82 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
83 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
84 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
85 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
86 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
87 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
88 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
89 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
90 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62
91 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
92 INT40827 Sstr1 Negative_regulation of Localization of Gh1 1 0.13 0 1.58
93 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
94 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
95 INT6768 Oprl1 Regulation of Localization of Prl 2 0.12 0 1.55
96 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
97 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
98 INT40887 Penk Regulation of Th 1 0.04 0 1.53
99 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
100 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
101 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
102 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
103 INT14375 Gal Positive_regulation of Localization of Prl 1 0.77 0 1.48
104 INT44504 Mt1a Positive_regulation of Prl 1 0.37 0 1.48
105 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
106 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
107 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
108 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
109 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
110 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
111 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
112 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
113 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4
114 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
115 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
116 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
117 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
118 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37
119 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
120 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
121 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
122 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
123 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
124 INT52568 HTR1D Regulation of Localization of Gh 2 0.20 0.16 1.34
125 INT87812 Penk Regulation of Prl 1 0.16 0 1.34
126 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
127 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
128 INT777 Prss12 Positive_regulation of Prl 1 0.19 0 1.33
129 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
130 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
131 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
132 INT90221 Binding of CYP2D6 and Cyp1a2 1 0.03 0.09 1.31
133 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
134 INT124925 Negative_regulation of Slc6a1 Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
135 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
136 INT95457 Nka1 Positive_regulation of Tacr1 1 0.63 0.29 1.3
137 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
138 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
139 INT48117 GH1 Positive_regulation of CGA 1 0.10 0 1.28
140 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
141 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
142 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
143 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
144 INT52205 Prl Positive_regulation of Gene_expression of Penk 1 0.52 0.15 1.25
145 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
146 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
147 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
148 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
149 INT202036 CAMK2N2 Negative_regulation of MMP3 1 0.00 0.73 1.24
150 INT70570 su Positive_regulation of Gh 1 0.01 0.15 1.24
151 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
152 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
153 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
154 INT63864 Oprd1 Regulation of Localization of Prl 2 0.16 0 1.23
155 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23
156 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
157 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
158 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
159 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
160 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
161 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
162 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
163 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
164 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
165 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
166 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
167 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
168 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
169 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
170 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
171 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
172 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
173 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
174 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
175 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
176 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
177 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
178 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
179 INT32480 Gh1 Positive_regulation of Gene_expression of Ghrh 1 0.35 0 1.15
180 INT69824 Negative_regulation of Binding of GHR and RYBP 1 0.01 0 1.14
181 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
182 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
183 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14
184 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
185 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13
186 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
187 INT86263 Binding of Tacr3 and Tac2 1 0.16 0.52 1.13
188 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
189 INT14199 GNRH1 Positive_regulation of Localization of Gh1 2 0.05 0 1.12
190 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 0.22 0.26 1.12
191 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
192 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
193 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11
194 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
195 INT29874 OXTR Negative_regulation of POMC 1 0.22 0 1.1
196 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
197 INT25036 TRH Regulation of Prl 4 0.27 1.75 1.09
198 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
199 INT40451 Cck Regulation of Prl 1 0.49 0 1.09
200 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to estradiol stimulus. They are ordered first by their pain relevance and then by number of times they were reported in response to estradiol stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158 Localization of Prl 2431 0.81 378.96 952.2
2 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82
3 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78
4 INT876 Localization of Gh1 843 0.80 67.75 340.82
5 INT162 Regulation of Prl 794 0.62 165.01 322.24
6 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
7 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66
8 INT3579 Localization of Oxt 555 0.81 43.35 292.44
9 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
10 INT1893 Localization of Gh 1041 0.79 340.23 256.58
11 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
12 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
13 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
14 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24
15 INT528 Gene_expression of Prl 693 0.78 217.18 192.2
16 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8
17 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18
18 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
19 INT880 Positive_regulation of Localization of Gh1 304 0.70 14.79 150.23
20 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
21 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
22 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
23 INT252 Localization of GH1 529 0.80 227.4 122.05
24 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
25 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
26 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
27 INT1530 Regulation of Gh 382 0.61 115.96 112.47
28 INT7327 Regulation of Th 164 0.62 29.67 110.14
29 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
30 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
31 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
32 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98
33 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5
34 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
35 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7
36 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
37 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43
38 INT875 Regulation of Localization of Gh1 166 0.62 12.87 84.97
39 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91
40 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
41 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16
42 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
43 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
44 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28
45 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71
46 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
47 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
48 INT6849 Localization of IL1B 229 0.81 112.56 69.63
49 INT451 Regulation of Oxt 142 0.62 22.07 69.42
50 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
51 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79
52 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47
53 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
54 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
55 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
56 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71
57 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
58 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
59 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45
60 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
61 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
62 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57
63 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
64 INT1782 Regulation of Gh1 125 0.62 22 55.74
65 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
66 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
67 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
68 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
69 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
70 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
71 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
72 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77
73 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
74 INT921 Regulation of GH1 172 0.60 52.88 51.04
75 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
76 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
77 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88
78 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75
79 INT531 Gene_expression of GH1 376 0.75 193.45 46.24
80 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06
81 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
82 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
83 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
84 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56
85 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
86 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78
87 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56
88 INT350 Localization of Th 79 0.80 10.26 41.17
89 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
90 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
91 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
92 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
93 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
94 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
95 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36
96 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39
97 INT7326 Transcription of Th 83 0.72 13.5 35.33
98 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3
99 INT6484 Binding of IL1B 122 0.47 75.84 35.07
100 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
101 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92
102 INT99610 Localization of MMP9 126 0.79 48.46 32.67
103 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39
104 INT9347 Localization of Il1b 58 0.81 26.13 31.53
105 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
106 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
107 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
108 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
109 INT8691 Localization of Insr 85 0.80 9.27 30.32
110 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
111 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
112 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
113 INT5300 Regulation of Insr 54 0.60 11.33 29.26
114 INT1166 Negative_regulation of Dbh 56 0.59 12.54 28.26
115 INT116737 Localization of Mif 63 0.81 52.97 28.11
116 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
117 INT37296 Binding of Esr1 117 0.43 62.51 27.33
118 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
119 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
120 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
121 INT20462 Binding of ESR1 210 0.44 102.7 26.34
122 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
123 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
124 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
125 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
126 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
127 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
128 INT93717 Gene_expression of Mmp3 85 0.78 33.95 24.89
129 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
130 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
131 INT4781 Gene_expression of TH 68 0.73 26.92 24.01
132 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
133 INT66026 Gene_expression of Cxcl1 74 0.78 31.87 23.37
134 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
135 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
136 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
137 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
138 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21
139 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
140 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15
141 INT39914 Negative_regulation of Cyp1a2 44 0.58 10.04 22
142 INT3382 Positive_regulation of Dbh 33 0.70 11.64 21.67
143 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
144 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
145 INT117527 Binding of Prkca 25 0.48 6.43 21.05
146 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
147 INT614 Gene_expression of Cxcl2 29 0.76 25.53 20.8
148 INT1512 Binding of Prl 73 0.48 26.22 20.63
149 INT17848 Binding of PTGS2 70 0.46 32.1 20.6
150 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
151 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
152 INT160 Regulation of Positive_regulation of Prl 37 0.62 7.56 20.09
153 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
154 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85
155 INT2960 Regulation of Dbh 32 0.47 10.32 18.94
156 INT1975 Regulation of Regulation of Prl 32 0.59 5.78 18.53
157 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49
158 INT5533 Binding of Oxt 43 0.48 8.69 18.35
159 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26
160 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
161 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
162 INT871 Negative_regulation of Gene_expression of Prl 53 0.58 18.89 17.79
163 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
164 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69
165 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
166 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
167 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
168 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
169 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96
170 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
171 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
172 INT51576 Positive_regulation of Cxcl1 42 0.69 20.12 16.41
173 INT4073 Localization of Dbh 28 0.81 6.06 16.37
174 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17
175 INT13716 Positive_regulation of TH 33 0.68 19.11 16
176 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
177 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
178 INT79458 Localization of Prkca 30 0.81 11.13 15.78
179 INT4242 Negative_regulation of Positive_regulation of Gh1 26 0.58 1.47 15.75
180 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
181 INT92354 Localization of ESR1 77 0.75 33.04 15.51
182 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
183 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
184 INT129 Localization of OXTR 51 0.80 11.08 15.36
185 INT81486 Localization of MMP3 31 0.81 12.94 15.21
186 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
187 INT12891 Negative_regulation of MMP3 41 0.58 17.99 15.06
188 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
189 INT129584 Positive_regulation of Stat3 97 0.68 87.07 14.86
190 INT49147 Gene_expression of Npy1r 27 0.76 6.57 14.75
191 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
192 INT7469 Positive_regulation of Gene_expression of Oxt 18 0.59 4.7 14.36
193 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
194 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
195 INT59870 Gene_expression of F3 51 0.65 51.83 14.01
196 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
197 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
198 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
199 INT24956 Gene_expression of Tacr3 22 0.74 7.21 13.37
200 INT95427 Positive_regulation of Mmp3 39 0.70 15.28 13.36
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