GO:0032367

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Name intracellular cholesterol transport
Categary Process
Go Slim No
Go Link GO:0032367
Unique Molecular Interactions 58
Total Molecular Interactions 70
Total Single Events 353
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for intracellular cholesterol transport. They are ordered first by their pain relevance and then by number of times they were reported for intracellular cholesterol transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
2 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
3 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
4 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
5 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
6 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
7 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
8 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
9 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
10 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
11 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
12 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
13 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
14 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
15 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
16 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
17 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
18 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
19 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
20 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
21 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
22 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12
23 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
24 INT42224 ABCA1 Positive_regulation of CYBB 1 0.01 0 0.09
25 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
26 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07
27 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
28 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06
29 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06
30 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05
31 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05
32 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05
33 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05
34 INT307282 Binding of PMP2 and NPC2 1 0.21 0.08 0.04
35 INT239333 Abcg1 Positive_regulation of RCT 1 0.06 1.29 0.03
36 INT230136 OSBPL8 Regulation of Binding of ABCA1 1 0.07 0.17 0.03
37 INT207343 Negative_regulation of CPOX Negative_regulation of Gene_expression of ABCA1 1 0.09 0 0.03
38 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0
39 INT229927 CD59 Negative_regulation of Binding of ABCA1 1 0.01 0 0
40 INT229923 Binding of ABCA1 and C9 1 0.00 0.74 0
41 INT284372 Binding of ABCA1 and AMT 1 0.00 0 0
42 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0
43 INT297056 Binding of ABCA1 and Oas1b 1 0.00 0.13 0
44 INT117795 ABCA1 Regulation of GHRL 1 0.00 0 0
45 INT284393 Positive_regulation of Binding of ABCA1 and Vegfa 1 0.00 0.36 0
46 INT326085 Prkaca Regulation of Phosphorylation of ABCA1 1 0.02 0.44 0
47 INT229981 Binding of ABCA1 and Cdca3 1 0.00 0.74 0
48 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
49 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0
50 INT344711 Nr1h3 Regulation of Abcg1 1 0.03 1.67 0
51 INT320848 Binding of Npc1 and Npc2 1 0.39 0 0
52 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
53 INT307283 Binding of ABCA1 and PMP2 1 0.00 0 0
54 INT326084 Prkaca Positive_regulation of Phosphorylation of ABCA1 1 0.06 0.44 0
55 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
56 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0
57 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for intracellular cholesterol transport. They are ordered first by their pain relevance and then by number of times they were reported in intracellular cholesterol transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
2 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
3 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
4 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
5 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
6 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
7 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
8 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
9 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
10 INT190089 Binding of Abca1 5 0.36 2.21 0.83
11 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
12 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
13 INT239289 Gene_expression of Abcg1 3 0.31 2.27 0.5
14 INT167468 Regulation of Gene_expression of ABCA1 5 0.52 0.08 0.43
15 INT209180 Transcription of ABCA1 4 0.47 1.09 0.39
16 INT345322 Regulation of Transcription of ABCA1 1 0.01 0 0.39
17 INT344684 Positive_regulation of Gene_expression of Abcg1 1 0.10 0.95 0.38
18 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37
19 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
20 INT239279 Regulation of Gene_expression of Abca1 2 0.44 2.42 0.26
21 INT344685 Positive_regulation of Binding of Abca1 1 0.12 0.76 0.26
22 INT284385 Positive_regulation of Localization of ABCA1 2 0.02 0.22 0.25
23 INT239287 Transcription of Abca1 1 0.32 1.87 0.21
24 INT300227 Positive_regulation of Binding of ABCA1 1 0.41 1.85 0.19
25 INT277709 Regulation of Binding of ABCA1 1 0.04 0.52 0.19
26 INT239308 Positive_regulation of Transcription of Abca1 1 0.28 0.67 0.18
27 INT239307 Positive_regulation of Abcg1 1 0.24 0.73 0.17
28 INT217387 Regulation of Abca1 3 0.27 2.01 0.15
29 INT187880 Binding of Abcg1 3 0.33 2.07 0.1
30 INT42227 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0 0.09
31 INT42226 Positive_regulation of Positive_regulation of ABCA1 1 0.02 0 0.09
32 INT229152 Negative_regulation of Abcg1 2 0.19 1.35 0.08
33 INT262061 Negative_regulation of Gene_expression of Abca1 1 0.19 0.68 0.08
34 INT239296 Negative_regulation of Abca1 3 0.26 3.83 0.04
35 INT288082 Positive_regulation of Npc2 2 0.48 0.67 0.04
36 INT288081 Positive_regulation of Positive_regulation of Npc2 1 0.47 0.67 0.04
37 INT253595 Localization of Abca1 2 0.37 0.35 0.03
38 INT239270 Transcription of Abcg1 1 0.27 1.21 0.03
39 INT320842 Localization of Npc2 1 0.76 1.01 0.03
40 INT288078 Gene_expression of Npc2 2 0.64 1.01 0
41 INT326077 Positive_regulation of Transcription of ABCA1 1 0.41 0.22 0
42 INT326076 Phosphorylation of ABCA1 1 0.73 0.66 0
43 INT307297 Binding of NPC2 1 0.34 0 0
44 INT326083 Positive_regulation of Phosphorylation of ABCA1 1 0.61 0.66 0
45 INT320844 Regulation of Npc2 1 0.43 0 0
46 INT320840 Binding of Npc2 1 0.46 1.81 0
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