GO:0032375

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Name negative regulation of cholesterol transport
Categary Process
Go Slim No
Go Link GO:0032375
Unique Molecular Interactions 144
Total Molecular Interactions 207
Total Single Events 1078
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cholesterol transport. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of cholesterol transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
2 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
3 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
4 INT116092 TFF2 Positive_regulation of NFKB1 1 0.17 0.06 1.77
5 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
6 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
7 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
8 INT147448 ADCYAP1 Regulation of Localization of NFKB1 1 0.47 1.12 1.15
9 INT101715 PLAT Positive_regulation of NFKB1 2 0.11 0.99 1.09
10 INT105113 Plat Positive_regulation of NFKB1 1 0.03 1.06 1.06
11 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
12 INT152388 Binding of NFKB1 and OPRM1 1 0.04 0.14 0.94
13 INT152389 Negative_regulation of Binding of NFKB1 and OPRM1 1 0.05 0.14 0.94
14 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87
15 INT161305 NFKB1 Positive_regulation of IL2 1 0.25 0.25 0.83
16 INT106312 NFKB1 Regulation of S100A4 1 0.14 1.1 0.83
17 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
18 INT140966 NFKB1 Positive_regulation of Positive_regulation of CPOX 1 0.08 0.66 0.8
19 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
20 INT146463 TNFSF10 Positive_regulation of NFKB1 2 0.08 2.45 0.71
21 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
22 INT103134 DCSTAMP Positive_regulation of NFKB1 2 0.07 1.43 0.7
23 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64
24 INT120851 NFKB1 Positive_regulation of Localization of TNF 3 0.04 2.05 0.62
25 INT66207 Positive_regulation of TNF Positive_regulation of NFKB1 1 0.42 0.08 0.61
26 INT144248 CGA Regulation of Positive_regulation of NFKB1 1 0.15 1.66 0.61
27 INT144256 CGA Regulation of Gene_expression of NFKB1 1 0.21 1.66 0.61
28 INT147071 NFKB1 Regulation of Gene_expression of PTGES 1 0.36 0.35 0.57
29 INT113548 NFKB1 Regulation of Localization of PLAU 1 0.26 1.93 0.55
30 INT156246 NFKB1 Regulation of Gene_expression of TNF 1 0.17 0.35 0.54
31 INT105111 Negative_regulation of Plat Positive_regulation of NFKB1 1 0.03 0.53 0.54
32 INT105110 Cxcl12 Positive_regulation of NFKB1 1 0.06 0.54 0.53
33 INT105108 Negative_regulation of Cxcl12 Positive_regulation of NFKB1 1 0.05 0.54 0.53
34 INT139834 NFKB1 Regulation of Gene_expression of SELE 1 0.18 0.49 0.5
35 INT139835 NFKB1 Regulation of SELE 1 0.41 0.49 0.5
36 INT106072 NFKB1 Positive_regulation of Gene_expression of A2M 1 0.19 0.75 0.49
37 INT135588 Positive_regulation of IKBKE Positive_regulation of NFKB1 1 0.18 1.29 0.48
38 INT135587 IKBKE Positive_regulation of NFKB1 1 0.18 1.28 0.48
39 INT191948 NFKB1 Regulation of Gene_expression of NOS2 1 0.38 1 0.47
40 INT106073 IL1B Positive_regulation of Positive_regulation of NFKB1 1 0.41 0.7 0.47
41 INT144245 CGA Negative_regulation of Positive_regulation of NFKB1 1 0.13 0.79 0.45
42 INT103128 Positive_regulation of DCSTAMP Positive_regulation of NFKB1 1 0.07 0.73 0.43
43 INT107699 IL1B Positive_regulation of Localization of NFKB1 1 0.03 0.13 0.41
44 INT84516 NFKB1 Positive_regulation of Gene_expression of TF 1 0.10 0.09 0.41
45 INT103131 Positive_regulation of NFKB1 Regulation of Gene_expression of IL8 1 0.27 0.68 0.4
46 INT166788 HRAS Negative_regulation of Phosphorylation of NFKB1 1 0.08 0.5 0.39
47 INT103795 Negative_regulation of SLC9A1 Negative_regulation of Positive_regulation of NFKB1 1 0.12 0.47 0.37
48 INT107705 DCSTAMP Positive_regulation of Localization of NFKB1 1 0.07 0.07 0.36
49 INT54570 Positive_regulation of NFKB1 Positive_regulation of Gene_expression of IL8 1 0.24 0.77 0.35
50 INT90388 NFKB1 Positive_regulation of CPOX 1 0.32 0.18 0.35
51 INT83347 GSR Negative_regulation of NFKB1 1 0.25 0.72 0.33
52 INT144251 TNF Positive_regulation of Gene_expression of NFKB1 1 0.43 0.65 0.3
53 INT80029 Binding of FAS and Positive_regulation of NFKB1 1 0.34 0.92 0.3
54 INT140386 Spp1 Positive_regulation of NFKB1 1 0.21 1.29 0.3
55 INT166789 HRAS Regulation of Positive_regulation of NFKB1 1 0.05 0.31 0.3
56 INT80031 FAS Positive_regulation of Positive_regulation of NFKB1 1 0.50 0.93 0.3
57 INT113558 Negative_regulation of NFKB1 Negative_regulation of Localization of PLAU 1 0.41 0.97 0.29
58 INT196631 PTGER2 Negative_regulation of NFKB1 1 0.00 0.32 0.28
59 INT144237 Negative_regulation of DCSTAMP Positive_regulation of NFKB1 1 0.06 0.72 0.28
60 INT144255 EGF Regulation of Positive_regulation of NFKB1 1 0.41 0.66 0.27
61 INT144239 CTSG Regulation of Positive_regulation of NFKB1 1 0.00 0.67 0.27
62 INT56071 NFKB1 Positive_regulation of Gene_expression of IL1B 1 0.36 0.4 0.27
63 INT125514 Positive_regulation of PRKDC Positive_regulation of Positive_regulation of NFKB1 1 0.07 0.44 0.26
64 INT125512 Gene_expression of NFKB1 Positive_regulation of GDF15 1 0.32 0.42 0.25
65 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
66 INT321224 TLR4 Positive_regulation of NFKB1 1 0.04 1.02 0.25
67 INT120849 PRL Positive_regulation of NFKB1 1 0.07 0.49 0.25
68 INT321223 CXCR1 Positive_regulation of NFKB1 1 0.00 1.02 0.25
69 INT321222 Binding of NFKB1 and NFKBIZ 1 0.02 1.11 0.24
70 INT125518 Binding of NFKB1 and GDF15 1 0.33 0.41 0.24
71 INT125519 Regulation of PLAT Positive_regulation of NFKB1 1 0.07 0.44 0.24
72 INT143950 Negative_regulation of NFKB1 Positive_regulation of Gene_expression of RELA 1 0.45 0.46 0.23
73 INT144238 TNF Positive_regulation of Protein_catabolism of NFKB1 1 0.40 0.35 0.22
74 INT104838 Binding of NFKB1 and IGKV2OR2-1 1 0.01 0 0.22
75 INT55164 Binding of NFKB1 and WRAP53 1 0.02 0.11 0.19
76 INT102805 NFKB1 Regulation of TCEAL1 1 0.25 0.77 0.17
77 INT116442 CD8B Negative_regulation of Positive_regulation of NFKB1 1 0.02 0 0.17
78 INT144252 CGA Positive_regulation of Positive_regulation of NFKB1 1 0.17 0.38 0.17
79 INT334106 APC Negative_regulation of NFKB1 1 0.25 1.37 0.17
80 INT116443 LY9 Negative_regulation of Positive_regulation of NFKB1 1 0.12 0 0.17
81 INT102806 NFKB1 Regulation of Gene_expression of TCEAL1 1 0.25 0.77 0.17
82 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
83 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
84 INT296030 Binding of NFKB1 and FOXP3 1 0.17 1.18 0.16
85 INT350013 ARID1B Regulation of Positive_regulation of NFKB1 1 0.00 1.77 0.16
86 INT43510 Apoa2 Positive_regulation of Localization of POMC 1 0.03 0 0.16
87 INT296078 Binding of NFKB1 and Gtf3a 1 0.00 1.18 0.16
88 INT104832 Binding of IL10 and NFKB1 1 0.15 0 0.15
89 INT139822 ZNF833P Negative_regulation of Transcription of NFKB1 1 0.03 0.11 0.15
90 INT61360 Regulation of TNF Positive_regulation of NFKB1 2 0.21 1.34 0.14
91 INT182780 NFKB1 Positive_regulation of IL1B 1 0.00 1.8 0.14
92 INT214480 SELPLG Negative_regulation of Positive_regulation of NFKB1 1 0.00 0.6 0.14
93 INT182782 NFKB1 Positive_regulation of IL6 1 0.00 1.8 0.14
94 INT139791 PRSS53 Negative_regulation of NFKB1 1 0.09 0.71 0.13
95 INT128281 Binding of JUND and NFKB1 1 0.36 0.39 0.13
96 INT306262 NFKB1 Positive_regulation of Transcription of PTGS2 1 0.42 0.31 0.12
97 INT33752 Apoa2 Regulation of Localization of POMC 1 0.06 0 0.12
98 INT33750 Apoa2 Regulation of Agt 1 0.07 0 0.12
99 INT33751 Apoa2 Positive_regulation of Positive_regulation of POMC 1 0.09 0 0.11
100 INT2458 Apoa2 Positive_regulation of Localization of Avp 1 0.10 0 0.11
101 INT306265 Binding of NFKB1 and NFKBIA 1 0.21 0.48 0.11
102 INT147073 NFKB1 Regulation of PTGS2 1 0.37 0 0.11
103 INT147072 NFKB1 Regulation of PTGES 1 0.36 0 0.11
104 INT139784 PRSS53 Negative_regulation of Positive_regulation of NFKB1 1 0.09 0.9 0.11
105 INT139785 TNFAIP8 Positive_regulation of Positive_regulation of NFKB1 1 0.19 0.89 0.11
106 INT294681 Tlr4 Positive_regulation of Positive_regulation of NFKB1 1 0.02 0.27 0.1
107 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
108 INT43121 Apoa2 Regulation of Smc1b 1 0.02 0 0.08
109 INT190885 Binding of Apoa2 and Hdl1 1 0.02 0.73 0.07
110 INT208218 NFKB1 Regulation of IRF6 1 0.01 0.07 0.07
111 INT296023 Positive_regulation of Apoa2 Negative_regulation of APOA1 1 0.50 0.35 0.05
112 INT296024 Apoa2 Negative_regulation of CETP 1 0.39 0.35 0.05
113 INT43124 Apoa2 Positive_regulation of Positive_regulation of NA 1 0.07 0 0.05
114 INT296025 Apoa2 Negative_regulation of APOA1 1 0.47 0.35 0.05
115 INT325025 Apoa2 Positive_regulation of Hdl1 1 0.05 1.03 0.04
116 INT172716 Binding of BCL3 and NFKB1 1 0.06 0.15 0.03
117 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03
118 INT139004 Mtpn Regulation of NFKB1 1 0.33 0.55 0
119 INT103286 Negative_regulation of IRF6 Positive_regulation of NFKB1 1 0.18 0 0
120 INT103287 IRF6 Positive_regulation of NFKB1 1 0.19 0 0
121 INT10903 Apoa2 Positive_regulation of Nppb 1 0.08 0.17 0
122 INT165509 CYBB Regulation of Gene_expression of NFKB1 1 0.02 0 0
123 INT156450 ANGPTL5 Positive_regulation of Positive_regulation of NFKB1 1 0.03 0 0
124 INT155918 NFKB1 Positive_regulation of Gene_expression of TNF 1 0.34 0 0
125 INT155173 NFKB1 Regulation of Gene_expression of NOS1 1 0.12 0.08 0
126 INT150957 STK16 Positive_regulation of Positive_regulation of NFKB1 1 0.04 0.08 0
127 INT352793 Binding of APOC1 and FGF21 1 0.01 2.76 0
128 INT47454 ras Positive_regulation of Apoa2 1 0.12 0.21 0
129 INT197816 Binding of MEN1 and NFKB1 1 0.05 0.07 0
130 INT10907 Apoa2 Positive_regulation of Localization of Nppb 1 0.09 0.23 0
131 INT155926 PARP1 Regulation of Binding of NFKB1 1 0.24 0.16 0
132 INT315070 Binding of IL8 and NFKB1 1 0.26 0.34 0
133 INT165510 HSPG2 Negative_regulation of Gene_expression of NFKB1 1 0.01 0.06 0
134 INT335513 EDIL3 Regulation of NFKB1 1 0.26 0.2 0
135 INT170589 NFKB1 Regulation of Gene_expression of ICAM1 1 0.27 0 0
136 INT156451 Negative_regulation of NFKB1 Negative_regulation of Gene_expression of ANGPTL5 1 0.03 0 0
137 INT292152 Binding of NFKB1 and REL 1 0.03 0.4 0
138 INT155922 PARP1 Positive_regulation of Binding of NFKB1 1 0.42 0.06 0
139 INT155924 Binding of PARP1 and NFKB1 1 0.34 0.23 0
140 INT164070 AKT1 Positive_regulation of NFKB1 1 0.32 0.09 0
141 INT164071 AKT1 Regulation of Positive_regulation of NFKB1 1 0.17 0.09 0
142 INT185161 Binding of APOA2 and Retn 1 0.03 1.01 0
143 INT155917 NFKB1 Positive_regulation of Gene_expression of IL6 1 0.29 0 0
144 INT155925 PARP1 Positive_regulation of NFKB1 1 0.42 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cholesterol transport. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of cholesterol transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32
2 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19
3 INT55170 Gene_expression of NFKB1 97 0.77 52.75 23.04
4 INT66208 Positive_regulation of Positive_regulation of NFKB1 45 0.68 20.17 22.62
5 INT25517 Regulation of NFKB1 41 0.61 22.28 16.09
6 INT54572 Negative_regulation of Positive_regulation of NFKB1 46 0.58 21.45 15.47
7 INT39733 Localization of NFKB1 59 0.79 22.76 13.99
8 INT55168 Binding of NFKB1 55 0.48 22.94 13.15
9 INT66210 Regulation of Positive_regulation of NFKB1 16 0.60 9.46 7.08
10 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
11 INT78728 Negative_regulation of Binding of NFKB1 18 0.58 6.89 5.39
12 INT66209 Negative_regulation of Localization of NFKB1 23 0.58 8.2 5.31
13 INT66211 Positive_regulation of Localization of NFKB1 20 0.68 8.18 5.01
14 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
15 INT56077 Protein_catabolism of NFKB1 16 0.98 8.03 3.94
16 INT56075 Transcription of NFKB1 13 0.71 9.03 3.83
17 INT79231 Positive_regulation of Gene_expression of NFKB1 18 0.67 9.16 3.66
18 INT134149 Negative_regulation of Gene_expression of NFKB1 7 0.55 4.25 3.63
19 INT139801 Phosphorylation of NFKB1 9 0.66 5.2 3.13
20 INT10556 Regulation of Apoa2 5 0.44 0.51 2.8
21 INT71305 Regulation of Gene_expression of NFKB1 9 0.61 5.41 2.44
22 INT2452 Localization of Apoa2 9 0.55 0 2.3
23 INT56078 Negative_regulation of Protein_catabolism of NFKB1 7 0.42 4.44 1.83
24 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81
25 INT76608 Regulation of Negative_regulation of NFKB1 1 0.33 0.53 1.75
26 INT165446 Positive_regulation of Phosphorylation of NFKB1 3 0.56 1.88 1.66
27 INT66214 Regulation of Binding of NFKB1 2 0.35 0.55 1.28
28 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89
29 INT88600 Positive_regulation of Binding of NFKB1 9 0.59 2.1 0.88
30 INT76609 Regulation of Regulation of NFKB1 2 0.20 0.97 0.79
31 INT56073 Positive_regulation of Transcription of NFKB1 4 0.46 1.88 0.77
32 INT25374 Negative_regulation of Negative_regulation of Apoa2 1 0.30 0.24 0.67
33 INT56074 Negative_regulation of Transcription of NFKB1 3 0.58 1.53 0.64
34 INT107106 Positive_regulation of Negative_regulation of NFKB1 1 0.33 1.26 0.54
35 INT10983 Binding of Apoa2 7 0.45 4.21 0.52
36 INT43397 Positive_regulation of Localization of Apoa2 1 0.09 0 0.48
37 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41
38 INT166794 Regulation of Localization of NFKB1 2 0.36 0.49 0.38
39 INT166795 Regulation of Phosphorylation of NFKB1 1 0.36 0.49 0.38
40 INT47453 Positive_regulation of Positive_regulation of Apoa2 3 0.31 1.17 0.32
41 INT43396 Regulation of Localization of Apoa2 1 0.09 0 0.3
42 INT297322 Binding of Apoa2 3 0.36 1.7 0.27
43 INT67227 Positive_regulation of Binding of Apoa2 2 0.26 1.31 0.25
44 INT2450 Negative_regulation of Positive_regulation of Apoa2 1 0.21 0 0.24
45 INT2449 Negative_regulation of Localization of Apoa2 1 0.19 0 0.22
46 INT323965 Protein_catabolism of Apoa2 1 0.01 0.34 0.22
47 INT180454 Negative_regulation of Apoa2 6 0.42 7.42 0.2
48 INT143955 Negative_regulation of Negative_regulation of NFKB1 1 0.35 0.48 0.2
49 INT10984 Negative_regulation of Binding of Apoa2 2 0.35 0.7 0.19
50 INT67225 Positive_regulation of Gene_expression of Apoa2 2 0.28 1.3 0.17
51 INT126804 Gene_expression of APOC1 1 0.75 1.06 0.14
52 INT264861 Regulation of Apoa2 5 0.44 4.25 0.11
53 INT279650 Transcription of Apoa2 1 0.02 0.79 0.1
54 INT279651 Positive_regulation of Transcription of Apoa2 1 0.02 0.84 0.1
55 INT180452 Localization of Apoa2 2 0.73 2.83 0.09
56 INT268708 Phosphorylation of APOC1 1 0.38 1.02 0.09
57 INT67224 Negative_regulation of Gene_expression of Apoa2 1 0.32 0.47 0.08
58 INT282084 Negative_regulation of Gene_expression of Apoa2 1 0.04 1.17 0.07
59 INT67226 Regulation of Gene_expression of Apoa2 1 0.15 0.51 0.07
60 INT35232 Regulation of Positive_regulation of Apoa2 1 0.48 0.18 0.05
61 INT335124 Positive_regulation of APOA2 1 0.15 0.43 0.05
62 INT199220 Negative_regulation of APOC1 1 0.02 1.89 0.03
63 INT325024 Regulation of Gene_expression of Apoa2 1 0.21 1.23 0.03
64 INT308624 Positive_regulation of Gene_expression of Apoa2 1 0.49 0.49 0
65 INT180453 Positive_regulation of Localization of Apoa2 1 0.49 1.84 0
66 INT309803 Negative_regulation of Binding of Apoa2 1 0.41 1.02 0
67 INT308631 Negative_regulation of Positive_regulation of Apoa2 1 0.42 0.5 0
68 INT309802 Positive_regulation of Binding of Apoa2 1 0.49 1.03 0
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