GO:0032402

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Name melanosome transport
Categary Process
Go Slim No
Go Link GO:0032402
Unique Molecular Interactions 108
Total Molecular Interactions 130
Total Single Events 1052
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for melanosome transport. They are ordered first by their pain relevance and then by number of times they were reported for melanosome transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT211710 Binding of Mc1r and a 7 0.44 0.37 4.78
2 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
3 INT145072 ASIP Negative_regulation of MC1R 1 0.29 0 1.52
4 INT69871 ASIP Negative_regulation of TYRP1 1 0.36 0 1.07
5 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
6 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
7 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
8 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
9 INT113224 Binding of ASIP and MC1R 1 0.00 0 0.75
10 INT288371 Binding of Atrn and a 1 0.39 0 0.74
11 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
12 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
13 INT250054 Positive_regulation of Binding of Gpr143 and Spdya 1 0.04 0.52 0.59
14 INT250053 Binding of Gpr143 and Spdya 1 0.03 0.51 0.59
15 INT93508 Binding of ASIP and Mc1r 1 0.02 0 0.47
16 INT69873 ASIP Negative_regulation of Binding of POMC 1 0.35 0 0.45
17 INT335594 Myo5a Regulation of Hmmr 1 0.00 0.39 0.45
18 INT288370 a Positive_regulation of Mc1r 1 0.39 0 0.44
19 INT346222 Positive_regulation of Braf Positive_regulation of Map2k1 1 0.15 0.67 0.39
20 INT28237 BBS2 Positive_regulation of Localization of Cck 1 0.04 0.33 0.39
21 INT107726 BIRC2 Regulation of ASIP 1 0.03 0.24 0.35
22 INT124475 MAP2K1 Positive_regulation of Positive_regulation of CPOX 1 0.04 0.68 0.33
23 INT172465 Binding of Rab27a and Rab27b 2 0.41 1.71 0.27
24 INT346224 Braf Negative_regulation of Phosphorylation of Map2k1 1 0.14 0.62 0.22
25 INT254687 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Mmp13 1 0.06 0.2 0.2
26 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
27 INT288372 Atrn Positive_regulation of a 1 0.52 0 0.19
28 INT288368 Atrn Positive_regulation of Binding of a 1 0.48 0 0.19
29 INT254683 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Plaur 1 0.01 0.07 0.18
30 INT254698 Gopc Positive_regulation of Positive_regulation of Map2k1 1 0.06 0.07 0.18
31 INT275318 Binding of Gpr143 and Adamts4 1 0.00 0.6 0.17
32 INT275319 Tg(Ngf)47Kma Positive_regulation of Gpr143 1 0.00 0.59 0.17
33 INT275317 Binding of Gpr143 and Adamts5 1 0.01 0.61 0.17
34 INT178269 Slc11a2 Regulation of a 1 0.06 0.97 0.16
35 INT304537 Map2k1 Positive_regulation of PRKG1 1 0.01 0.66 0.16
36 INT304503 Map2k1 Positive_regulation of Nos1 1 0.07 0.66 0.16
37 INT178266 Raly Regulation of a 1 0.14 0.97 0.16
38 INT97541 Gtf3a Negative_regulation of a 1 0.03 0.08 0.15
39 INT97544 Pomc Negative_regulation of a 1 0.19 0.07 0.15
40 INT97548 KITLG Negative_regulation of a 1 0.01 0.08 0.15
41 INT304499 Map2k1 Positive_regulation of Mapk1 1 0.12 0.8 0.1
42 INT224531 Positive_regulation of Map2k1 Positive_regulation of Positive_regulation of Ankh 1 0.07 0.54 0.09
43 INT47719 Gpr143 Regulation of Grhpr 1 0.00 0.08 0.08
44 INT232897 Binding of Rab27a and SAMSN1 1 0.00 0.73 0.08
45 INT107722 ASIP Negative_regulation of EIF4E1B 1 0.02 0.43 0.07
46 INT57965 Myo5a Negative_regulation of Cyp2e1 1 0.01 0.09 0.07
47 INT107727 ASIP Negative_regulation of RRM2 1 0.29 0.43 0.07
48 INT107725 ASIP Negative_regulation of EVI2B 1 0.41 0.43 0.06
49 INT107724 ASIP Negative_regulation of NR4A3 1 0.15 0.43 0.06
50 INT47717 Gpr143 Regulation of Cyp3a62 1 0.02 0.05 0.05
51 INT194699 MAP2K1 Positive_regulation of MAPK8 1 0.05 0 0.04
52 INT194703 MAP2K1 Positive_regulation of MAP2K6 1 0.21 0 0.04
53 INT194677 Binding of GADD45A and MAP2K1 1 0.27 0 0.04
54 INT194719 MAP2K1 Positive_regulation of MAPK1 1 0.27 0 0.04
55 INT194701 MAP2K1 Positive_regulation of MAP2K4 1 0.21 0 0.04
56 INT194732 MAP2K1 Positive_regulation of Gene_expression of MAPK1 1 0.27 0 0.04
57 INT194691 MAP2K1 Positive_regulation of MAP2K3 1 0.23 0 0.04
58 INT295479 PRKCA Positive_regulation of MAP2K1 1 0.14 0.35 0.03
59 INT269502 Lta Negative_regulation of Map2k1 1 0.17 0.48 0.03
60 INT295474 IRF6 Positive_regulation of MAP2K1 1 0.18 0.41 0.03
61 INT47720 Gpr143 Regulation of Nqo1 1 0.01 0 0
62 INT254689 Gene_expression of Map2k2 Positive_regulation of Map2k1 1 0.30 0.4 0
63 INT339113 Binding of ASIP and ERBB2 1 0.00 0.64 0
64 INT254707 Positive_regulation of Map2k1 Regulation of Gene_expression of BAK1 1 0.05 0.67 0
65 INT254692 Positive_regulation of Map2k1 Regulation of Gene_expression of Mdk 1 0.05 0.42 0
66 INT240420 Myo5a Positive_regulation of CD4 1 0.06 0.27 0
67 INT232890 Binding of Rab27a and Gopc 1 0.01 0.3 0
68 INT290482 GPR143 Regulation of Gene_expression of Mitf 1 0.36 0.64 0
69 INT234800 RAB27A Positive_regulation of INS 1 0.02 1.26 0
70 INT215246 Binding of Rab27a and Rph3a 1 0.07 0.26 0
71 INT172464 Binding of Rab27a and Myc 1 0.13 0.69 0
72 INT313802 Binding of ASIP and YOD1 1 0.00 0.19 0
73 INT290483 RAB27A Regulation of Gene_expression of Mitf 1 0.25 0.64 0
74 INT178267 Alb Positive_regulation of Gene_expression of a 1 0.19 0.9 0
75 INT178268 Alb Regulation of Gene_expression of a 1 0.18 0.9 0
76 INT290046 RAB27A Regulation of RPE 1 0.03 0.75 0
77 INT254693 Gene_expression of Map2k1 Regulation of Map2k2 1 0.29 0.78 0
78 INT186401 Binding of MKKS and MKS1 1 0.09 0.07 0
79 INT215239 Binding of Rab27a and Sytl4 1 0.26 0.26 0
80 INT254686 Gene_expression of Map2k1 Regulation of Gene_expression of Mdk 1 0.08 0.42 0
81 INT254703 Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 0.91 0
82 INT254696 Map2k2 Regulation of Map2k1 1 0.18 0.78 0
83 INT290045 RAB27A Positive_regulation of CHM 1 0.16 0.92 0
84 INT311816 CD79A Positive_regulation of RAB27A 1 0.01 0.47 0
85 INT234793 RAB27A Positive_regulation of Localization of INS 1 0.03 1.26 0
86 INT254706 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
87 INT215242 Binding of Rab27a and Noc2l 1 0.07 0.26 0
88 INT254704 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 1.43 0
89 INT254702 Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0
90 INT254684 Map2k2 Positive_regulation of Map2k1 1 0.45 0.4 0
91 INT339100 Binding of ASIP and EGFR 1 0.00 0.58 0
92 INT232894 Binding of ABR and Rab27a 1 0.08 0.3 0
93 INT234795 Negative_regulation of CHM Negative_regulation of RAB27A 1 0.01 0.8 0
94 INT131787 Binding of Myo5a and Pon1 1 0.02 0.06 0
95 INT336606 Binding of Mapk8 and Map2k1 1 0.09 0.72 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for melanosome transport. They are ordered first by their pain relevance and then by number of times they were reported in melanosome transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT55251 Gene_expression of a 142 0.67 81.21 23.03
2 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
3 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
4 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
5 INT93507 Gene_expression of ASIP 14 0.60 3.98 7.55
6 INT250050 Gene_expression of Gpr143 1 0.48 5.76 6.53
7 INT93137 Negative_regulation of Map2k1 17 0.42 4.51 6.49
8 INT250048 Positive_regulation of Gpr143 12 0.43 5.85 6.1
9 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
10 INT94652 Binding of a 15 0.48 4.18 5.4
11 INT135440 Positive_regulation of Phosphorylation of Map2k1 5 0.49 1.32 5.22
12 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22
13 INT178261 Positive_regulation of Gene_expression of a 23 0.55 14.67 4.07
14 INT106065 Negative_regulation of MAP2K1 27 0.57 12.69 3.97
15 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16
16 INT211708 Regulation of a 4 0.42 1.92 3.15
17 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02
18 INT199798 Positive_regulation of BBS2 2 0.50 5.85 2.55
19 INT178246 Negative_regulation of Gene_expression of a 8 0.43 4.27 2.19
20 INT178260 Positive_regulation of a 6 0.50 3.09 2.08
21 INT127756 Negative_regulation of Map2k1 10 0.41 6.69 2.04
22 INT91608 Negative_regulation of ASIP 3 0.40 0.51 2.04
23 INT88269 Binding of ASIP 4 0.19 0.41 1.82
24 INT135444 Regulation of Map2k1 4 0.44 1.15 1.77
25 INT104121 Positive_regulation of MAP2K1 8 0.61 4.84 1.41
26 INT178249 Regulation of Gene_expression of a 4 0.35 2.3 1.39
27 INT175525 Positive_regulation of Phosphorylation of Map2k1 8 0.33 7.02 1.37
28 INT71782 Gene_expression of MAP2K1 7 0.68 3.17 1.37
29 INT311241 Transcription of Myo5a 1 0.50 1.61 1.37
30 INT250046 Regulation of Gene_expression of Gpr143 1 0.28 0.87 1.23
31 INT178255 Localization of a 4 0.65 0.72 1.1
32 INT177481 Negative_regulation of BBS2 6 0.31 5.34 1.06
33 INT90898 Negative_regulation of Rab27a 5 0.43 1.99 1.04
34 INT138287 Gene_expression of Map2k1 69 0.65 46.14 1.02
35 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93
36 INT178252 Transcription of a 3 0.67 0.73 0.9
37 INT250045 Positive_regulation of Positive_regulation of Gpr143 1 0.31 0.4 0.85
38 INT28236 Localization of BBS2 2 0.54 1.9 0.83
39 INT145073 Regulation of Gene_expression of ASIP 1 0.27 0 0.83
40 INT274178 Binding of BBS2 1 0.27 2.12 0.82
41 INT71778 Positive_regulation of Gene_expression of MAP2K1 2 0.36 0.37 0.81
42 INT118986 Positive_regulation of Gene_expression of ASIP 1 0.39 0.97 0.8
43 INT57958 Positive_regulation of Myo5a 9 0.41 7.52 0.77
44 INT211909 Regulation of Positive_regulation of Map2k1 1 0.21 0.47 0.76
45 INT90899 Gene_expression of Rab27a 49 0.78 26.71 0.74
46 INT163222 Protein_catabolism of a 2 1.00 1.17 0.56
47 INT211707 Positive_regulation of Transcription of a 2 0.51 0.27 0.55
48 INT104120 Positive_regulation of Positive_regulation of MAP2K1 1 0.49 0 0.54
49 INT90897 Regulation of Rab27a 6 0.45 3.28 0.5
50 INT305031 Positive_regulation of GPR143 1 0.49 0.41 0.5
51 INT236915 Binding of Map2k1 2 0.15 1.51 0.49
52 INT274177 Positive_regulation of Gene_expression of BBS2 2 0.36 1.55 0.49
53 INT178248 Negative_regulation of a 4 0.43 1 0.46
54 INT250043 Positive_regulation of Gene_expression of Gpr143 1 0.29 0.56 0.4
55 INT138282 Positive_regulation of Gene_expression of Map2k1 13 0.49 7.46 0.39
56 INT304528 Gene_expression of Map2k1 3 0.58 1.76 0.37
57 INT195574 Localization of Myo5a 4 0.34 1.1 0.36
58 INT346261 Gene_expression of MKKS 1 0.40 0.66 0.34
59 INT14382 Regulation of BBS2 3 0.43 2.07 0.33
60 INT304526 Binding of Map2k1 1 0.11 0.6 0.32
61 INT346249 Phosphorylation of MKKS 1 0.43 0.61 0.31
62 INT274176 Negative_regulation of Gene_expression of BBS2 1 0.31 0.94 0.29
63 INT240205 Regulation of MAP2K1 3 0.26 0.44 0.28
64 INT53212 Negative_regulation of RAB27A 4 0.57 2.46 0.26
65 INT250049 Positive_regulation of Localization of Gpr143 1 0.31 0.31 0.25
66 INT250044 Localization of Gpr143 1 0.46 0.31 0.25
67 INT175506 Regulation of Positive_regulation of Map2k1 2 0.32 1.58 0.23
68 INT304519 Positive_regulation of Gene_expression of Map2k1 1 0.15 0.41 0.22
69 INT172442 Binding of Rab27a 3 0.37 1.5 0.21
70 INT284157 Regulation of Negative_regulation of BBS2 1 0.08 1.08 0.21
71 INT240411 Negative_regulation of Binding of Myo5a 1 0.09 0.97 0.21
72 INT129672 Positive_regulation of Rab27a 2 0.69 2.72 0.19
73 INT272845 Transcription of BBS2 1 0.04 0.42 0.16
74 INT178256 Negative_regulation of Binding of a 1 0.33 0.94 0.15
75 INT254671 Regulation of Map2k1 5 0.43 1.83 0.14
76 INT265533 Negative_regulation of Phosphorylation of Map2k1 1 0.41 0 0.14
77 INT175527 Localization of Map2k1 4 0.31 2.41 0.13
78 INT192783 Phosphorylation of Myo5a 1 0.04 2.01 0.12
79 INT254673 Positive_regulation of Positive_regulation of Map2k1 3 0.35 1.65 0.11
80 INT160258 Negative_regulation of Myo5a 3 0.35 3.96 0.09
81 INT276280 Regulation of Localization of a 1 0.37 0.33 0.09
82 INT215418 Positive_regulation of Phosphorylation of MAP2K1 1 0.03 0.51 0.08
83 INT215420 Phosphorylation of MAP2K1 1 0.05 0.51 0.08
84 INT183818 Positive_regulation of MKKS 1 0.01 1.82 0.05
85 INT192784 Positive_regulation of Gene_expression of Myo5a 2 0.45 3.39 0.04
86 INT281764 Negative_regulation of Gene_expression of Map2k1 1 0.18 1.11 0.04
87 INT172463 Gene_expression of RAB27A 6 0.65 3.95 0.03
88 INT172449 Positive_regulation of Gene_expression of Rab27a 4 0.50 2.37 0.03
89 INT329571 Binding of MAP2K1 2 0.11 0.4 0
90 INT172459 Localization of Rab27a 2 0.75 1.57 0
91 INT290075 Regulation of RAB27A 2 0.44 1.31 0
92 INT178259 Positive_regulation of Binding of a 1 0.39 0.39 0
93 INT47713 Negative_regulation of Gpr143 1 0.03 0 0
94 INT215223 Regulation of Localization of Rab27a 1 0.45 0.73 0
95 INT281758 Positive_regulation of Protein_catabolism of Map2k1 1 0.29 0.13 0
96 INT290467 Gene_expression of GPR143 1 0.21 0.32 0
97 INT286005 Positive_regulation of Binding of Myo5a 1 0.41 0.97 0
98 INT290465 Regulation of GPR143 1 0.19 0.58 0
99 INT234815 Phosphorylation of RAB27A 1 0.37 0.77 0
100 INT281756 Protein_catabolism of Map2k1 1 0.42 0.13 0
101 INT177482 Negative_regulation of Negative_regulation of BBS2 1 0.03 0.73 0
102 INT172455 Protein_catabolism of Rab27a 1 1.00 2.11 0
103 INT311859 Positive_regulation of RAB27A 1 0.19 2.95 0
104 INT175533 Regulation of Gene_expression of Map2k1 1 0.20 1.55 0
105 INT286004 Positive_regulation of Positive_regulation of Myo5a 1 0.41 0.58 0
106 INT172443 Negative_regulation of Transcription of Rab27a 1 0.43 0.4 0
107 INT172457 Positive_regulation of Localization of Rab27a 1 0.50 0.38 0
108 INT178254 Regulation of Transcription of a 1 0.35 0.47 0
109 INT172450 Regulation of Gene_expression of Rab27a 1 0.45 0.37 0
110 INT172446 Transcription of Rab27a 1 0.69 0.39 0
111 INT311860 Binding of RAB27A 1 0.10 0.52 0
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