GO:0032421

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Name stereocilium bundle
Categary Component
Go Slim No
Go Link GO:0032421
Unique Molecular Interactions 114
Total Molecular Interactions 168
Total Single Events 2058
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for stereocilium bundle. They are ordered first by their pain relevance and then by number of times they were reported for stereocilium bundle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
2 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
3 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69
4 INT154685 Syt17 Positive_regulation of Trpa1 1 0.32 0.71 1.4
5 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3
6 INT134384 Trpa1 Negative_regulation of Gene_expression of Trpm8 1 0.47 1.21 1.02
7 INT166625 Acer3 Positive_regulation of Trpa1 1 0.01 1.91 1
8 INT307100 Trpv1 Regulation of Binding of Trpa1 1 0.31 1.81 0.97
9 INT307103 Trpa1 Regulation of Binding of Trpv1 1 0.31 1.81 0.97
10 INT149389 Olfr1241 Positive_regulation of Trpa1 1 0.02 0.31 0.94
11 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
12 INT221916 RPS3AP18 Negative_regulation of Positive_regulation of Trpa1 1 0.00 0.75 0.93
13 INT149391 Trpa1 Positive_regulation of Positive_regulation of Olfr1241 1 0.03 0.26 0.88
14 INT150643 Binding of Bdkrb2 and Trpa1 1 0.36 0.55 0.78
15 INT166902 NPPB Positive_regulation of TRPA1 1 0.78 0.76 0.77
16 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74
17 INT142225 Urb1 Positive_regulation of Trpa1 1 0.04 0.59 0.71
18 INT307754 Ik Negative_regulation of Trpa1 1 0.07 0.08 0.71
19 INT221938 Binding of TRPA1 and Tceb1 1 0.02 0 0.71
20 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71
21 INT283049 Car2 Positive_regulation of Trpa1 1 0.20 1.33 0.67
22 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64
23 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63
24 INT252857 Binding of F2rl1 and Trpa1 1 0.22 0.84 0.63
25 INT252859 Binding of Ngf and Trpa1 1 0.19 0.84 0.62
26 INT284792 Binding of Trpa1 and DRGX 1 0.02 0.66 0.6
27 INT284790 Trpa1 Positive_regulation of Regulation of Napa 1 0.19 0 0.59
28 INT220051 Fcgr4 Positive_regulation of Gene_expression of Ido1 1 0.01 1.24 0.55
29 INT138352 Foxm1 Positive_regulation of Trpa1 1 0.05 0.33 0.51
30 INT142230 Urb1 Positive_regulation of Gene_expression of Trpa1 1 0.04 0.4 0.5
31 INT142226 Trpa1 Regulation of Trpv1 2 0.35 0.39 0.44
32 INT104447 Ido1 Negative_regulation of Binding of Atp7b 1 0.00 0.68 0.43
33 INT296231 Anxa1 Regulation of Gene_expression of Trpa1 1 0.03 0.57 0.43
34 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38
35 INT167045 TRPA1 Regulation of PTGS1 1 0.19 0.1 0.35
36 INT167047 TRPA1 Regulation of CNR1 1 0.12 0.1 0.35
37 INT167046 TRPA1 Regulation of TRPV1 1 0.48 0.1 0.35
38 INT146247 Pcbd1 Positive_regulation of Trpa1 1 0.02 0 0.31
39 INT166901 NPPB Positive_regulation of Gene_expression of TRPA1 1 0.68 0.33 0.3
40 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27
41 INT221939 Tceb1 Negative_regulation of Positive_regulation of TRPA1 1 0.02 0 0.26
42 INT284783 Napa Positive_regulation of Positive_regulation of Trpa1 1 0.20 0 0.25
43 INT196133 Binding of Gopc and Trpa1 1 0.12 0 0.22
44 INT284787 Napa Positive_regulation of Binding of Trpa1 1 0.22 0 0.2
45 INT284782 Napa Positive_regulation of Trpa1 1 0.30 0 0.2
46 INT242319 D12Pgn2 Positive_regulation of Trpa1 1 0.01 0.47 0.19
47 INT220053 Il10 Positive_regulation of Ido1 1 0.14 0.74 0.19
48 INT242632 Ret Positive_regulation of Gene_expression of Trpa1 1 0.33 0.09 0.18
49 INT149797 RGD1565648 Positive_regulation of Trpa1 1 0.00 0.18 0.17
50 INT149798 Atp7b Positive_regulation of Trpa1 1 0.23 0.18 0.17
51 INT163273 H2BFM Regulation of TRPA1 1 0.23 0.42 0.17
52 INT137869 Gene_expression of Artn Positive_regulation of Gene_expression of Trpa1 1 0.52 0.16 0.17
53 INT142229 Trpa1 Regulation of Trpv4 1 0.15 0.1 0.17
54 INT142223 Trpa1 Negative_regulation of Trpm8 1 0.20 0.1 0.17
55 INT242318 Ptgds Positive_regulation of Trpa1 1 0.29 0.06 0.16
56 INT260059 AKTIP Positive_regulation of TRPA1 1 0.02 0 0.15
57 INT221937 Negative_regulation of Binding of TRPA1 and Tceb1 1 0.02 0 0.14
58 INT141497 Pyroxd1 Positive_regulation of Trpa1 1 0.01 0.18 0.14
59 INT141496 Negative_regulation of Pyroxd1 Positive_regulation of Trpa1 1 0.01 0.18 0.14
60 INT296233 Binding of Anxa1 and Trpa1 1 0.03 0.78 0.14
61 INT323345 Ido1 Positive_regulation of Gene_expression of Tlr4 1 0.14 0.69 0.13
62 INT268083 Ido1 Negative_regulation of Tyrp1 1 0.22 0 0.13
63 INT150061 Binding of TRPV1 and Trpa1 1 0.24 0.1 0.13
64 INT268082 Ido1 Positive_regulation of Gpr35 1 0.04 0 0.13
65 INT296238 Trpm8 Regulation of Trpa1 1 0.30 0.21 0.12
66 INT146244 Trpa1 Regulation of HalphaSS 1 0.01 0 0.11
67 INT146242 Trpa1 Regulation of Trpv1 1 0.24 0 0.11
68 INT146246 HalphaSS Positive_regulation of Trpa1 1 0.02 0 0.1
69 INT151094 Binding of TRPA1 and TRPM8 1 0.41 0.2 0.1
70 INT170330 Regulation of Regulation of Gene_expression of Ido1 1 0.01 0.38 0.08
71 INT226906 Binding of Ido1 and Il6 1 0.07 0.67 0.08
72 INT284786 Trpv1 Positive_regulation of Gene_expression of Trpa1 1 0.45 0.36 0.07
73 INT167271 Binding of Ezr and Clic5 1 0.54 0.07 0.06
74 INT268088 Tdo2 Positive_regulation of Gene_expression of Ido1 1 0.41 0.09 0.04
75 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
76 INT170337 Gene_expression of Ido1 Positive_regulation of MRXS5 1 0.01 0.12 0.03
77 INT170326 Ido1 Positive_regulation of Cpox 1 0.07 0.12 0.03
78 INT170338 Gene_expression of Ido1 Positive_regulation of IGHD2-15 1 0.02 0.12 0.03
79 INT170327 Ido1 Positive_regulation of Gene_expression of Cpox 1 0.07 0.12 0.03
80 INT321781 Whrn Positive_regulation of Gopc 1 0.18 0 0
81 INT321770 Binding of Myo15 and Whrn 1 0.43 0.08 0
82 INT321778 Binding of P4hb and Whrn 1 0.33 0.06 0
83 INT321776 Whrn Regulation of Localization of Gsn 1 0.23 0.07 0
84 INT286422 Binding of Cdc42ep5 and Dock4 1 0.01 0.84 0
85 INT355221 Binding of Espn and Ocln 1 0.01 0 0
86 INT355223 Binding of Espn and Tjp2 1 0.01 0 0
87 INT321779 Whrn Positive_regulation of Myo15 1 0.39 0 0
88 INT276582 Binding of Espn and Plce1 1 0.01 0.34 0
89 INT321775 Binding of Whrn and Gsn 1 0.46 0.42 0
90 INT330384 IER3 Regulation of USH2A 1 0.00 0.87 0
91 INT321767 Myo15 Positive_regulation of Gopc 1 0.16 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for stereocilium bundle. They are ordered first by their pain relevance and then by number of times they were reported in stereocilium bundle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65
2 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9
3 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98
4 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14
5 INT149387 Negative_regulation of Trpa1 55 0.59 21.91 28.31
6 INT127499 Positive_regulation of TRPA1 72 0.70 21.7 26.86
7 INT127500 Gene_expression of TRPA1 79 0.78 24.58 23.3
8 INT134596 Regulation of Trpa1 32 0.62 18.78 17.02
9 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98
10 INT120432 Regulation of Trpa1 22 0.61 9.65 12.36
11 INT134597 Binding of Trpa1 21 0.48 9.41 9.74
12 INT146346 Negative_regulation of Gene_expression of Trpa1 15 0.59 11.76 8.83
13 INT146241 Positive_regulation of Gene_expression of Trpa1 23 0.69 8.07 8.74
14 INT130502 Negative_regulation of Trpa1 17 0.59 5.75 8.06
15 INT170295 Positive_regulation of Ido1 40 0.67 28.89 7.61
16 INT134379 Binding of Trpa1 13 0.48 7.16 7.27
17 INT131745 Positive_regulation of Gene_expression of Trpa1 13 0.69 8.07 6.95
18 INT126484 Localization of Trpa1 15 0.80 4.08 6.64
19 INT131744 Transcription of Trpa1 9 0.68 7.67 6.47
20 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06
21 INT169687 Regulation of Gene_expression of Trpa1 10 0.60 7.02 5.94
22 INT147869 Positive_regulation of Gene_expression of TRPA1 5 0.70 5.33 5.21
23 INT11298 Gene_expression of Ido1 6 0.58 6.71 4.85
24 INT170311 Negative_regulation of Ido1 16 0.48 14.47 4.81
25 INT143557 Positive_regulation of Ido1 6 0.40 5.34 4.8
26 INT147870 Binding of TRPA1 11 0.48 3.12 4.77
27 INT159899 Localization of Trpa1 9 0.75 1.9 3.4
28 INT136891 Negative_regulation of TRPA1 7 0.43 2.45 3.06
29 INT147542 Negative_regulation of Positive_regulation of Trpa1 6 0.59 2.63 3
30 INT168745 Negative_regulation of Regulation of Trpa1 1 0.43 3.26 2.87
31 INT142500 Transcription of Trpa1 11 0.67 5.27 2.78
32 INT151865 Regulation of TRPA1 5 0.45 2.78 2.7
33 INT138351 Negative_regulation of Gene_expression of Trpa1 6 0.43 2.77 2.44
34 INT147543 Positive_regulation of Positive_regulation of Trpa1 7 0.69 2.24 2.38
35 INT170323 Regulation of Gene_expression of Ido1 11 0.60 8.74 2.33
36 INT269695 Negative_regulation of Negative_regulation of Trpa1 3 0.43 1.94 2.25
37 INT151818 Negative_regulation of Positive_regulation of TRPA1 3 0.58 0.56 1.96
38 INT143561 Positive_regulation of Positive_regulation of Ido1 1 0.36 1.84 1.89
39 INT150248 Positive_regulation of Gene_expression of Ido1 2 0.43 2.68 1.77
40 INT304624 Positive_regulation of Regulation of Trpa1 1 0.44 2.64 1.76
41 INT134382 Positive_regulation of Transcription of Trpa1 2 0.46 2.48 1.71
42 INT147224 Negative_regulation of Positive_regulation of Trpa1 2 0.58 2.92 1.66
43 INT151096 Localization of TRPA1 8 0.80 2.06 1.65
44 INT131743 Regulation of Gene_expression of Trpa1 2 0.44 1.76 1.58
45 INT127323 Positive_regulation of Positive_regulation of Trpa1 8 0.69 0.96 1.42
46 INT269692 Regulation of Negative_regulation of Trpa1 1 0.45 0.17 1.39
47 INT154487 Regulation of Positive_regulation of TRPA1 2 0.27 1.18 1.19
48 INT220046 Positive_regulation of Negative_regulation of Ido1 1 0.41 2.98 1.12
49 INT265086 Regulation of Negative_regulation of Trpa1 1 0.44 1.44 1.09
50 INT88177 Negative_regulation of Ido1 3 0.25 0.51 1.02
51 INT125903 Gene_expression of Espn 2 0.06 0.77 0.94
52 INT220043 Positive_regulation of Positive_regulation of Ido1 2 0.41 1.94 0.83
53 INT143559 Positive_regulation of Protein_catabolism of Ido1 1 0.29 0.93 0.79
54 INT143560 Protein_catabolism of Ido1 1 0.52 0.93 0.79
55 INT221914 Negative_regulation of Binding of Trpa1 1 0.18 0.65 0.77
56 INT143558 Negative_regulation of Negative_regulation of Ido1 1 0.25 0.49 0.76
57 INT148471 Negative_regulation of Transcription of Trpa1 1 0.38 0.29 0.69
58 INT221915 Positive_regulation of Localization of Trpa1 1 0.21 0.5 0.63
59 INT265087 Regulation of Binding of Trpa1 1 0.44 0.61 0.58
60 INT151819 Positive_regulation of Positive_regulation of TRPA1 3 0.50 0.15 0.51
61 INT170299 Negative_regulation of Gene_expression of Ido1 12 0.57 2.59 0.5
62 INT220048 Protein_catabolism of Ido1 1 0.81 1.03 0.47
63 INT135078 Positive_regulation of Localization of Trpa1 2 0.49 0.14 0.43
64 INT270034 Negative_regulation of Positive_regulation of Ido1 1 0.19 2.23 0.42
65 INT283042 Regulation of Transcription of Trpa1 1 0.43 1.31 0.4
66 INT270027 Regulation of Positive_regulation of Ido1 1 0.23 1.17 0.39
67 INT260061 Positive_regulation of Binding of TRPA1 1 0.45 0.18 0.39
68 INT170318 Regulation of Ido1 6 0.38 2.63 0.38
69 INT284781 Positive_regulation of Binding of Trpa1 1 0.45 0 0.36
70 INT307753 Positive_regulation of Negative_regulation of Trpa1 1 0.50 0 0.25
71 INT139301 Regulation of Espn 1 0.02 0.38 0.24
72 INT113855 Regulation of Phosphorylation of Espn 1 0.04 0.06 0.2
73 INT113856 Phosphorylation of Espn 1 0.08 0.06 0.2
74 INT113857 Positive_regulation of Phosphorylation of Espn 1 0.06 0.06 0.2
75 INT244266 Gene_expression of USH2A 2 0.04 0.19 0.17
76 INT223459 Gene_expression of Dock4 2 0.71 1.5 0.16
77 INT151866 Transcription of TRPA1 1 0.69 0.09 0.16
78 INT283041 Positive_regulation of Transcription of Trpa1 1 0.48 0.87 0.16
79 INT223465 Regulation of Dock4 1 0.08 0.13 0.16
80 INT223463 Regulation of Gene_expression of Dock4 1 0.31 0.13 0.16
81 INT11299 Binding of Ido1 1 0.31 0.15 0.15
82 INT213080 Gene_expression of Clic5 1 0.04 0.51 0.15
83 INT334876 Negative_regulation of Transcription of Trpa1 1 0.23 0.25 0.13
84 INT241880 Regulation of Regulation of Trpa1 1 0.37 0.28 0.11
85 INT170320 Binding of Ido1 1 0.36 0.19 0.11
86 INT170297 Positive_regulation of Regulation of Ido1 1 0.39 0.29 0.1
87 INT167268 Positive_regulation of Clic5 1 0.44 0.15 0.1
88 INT168526 Localization of USH2A 1 0.20 0.17 0.1
89 INT339608 Localization of Ido1 1 0.14 0.41 0.08
90 INT208274 Negative_regulation of Espn 1 0.03 0.66 0.08
91 INT167269 Transcription of Clic5 1 0.72 0.07 0.07
92 INT321729 Binding of Whrn 1 0.45 0 0.06
93 INT141282 Regulation of Positive_regulation of Trpa1 1 0.45 0 0.06
94 INT261869 Regulation of Positive_regulation of Trpa1 1 0.35 0 0.06
95 INT277552 Gene_expression of Whrn 2 0.57 0.75 0.04
96 INT150246 Negative_regulation of Gene_expression of Ido1 1 0.07 0 0
97 INT330356 Regulation of USH2A 1 0.01 0.86 0
98 INT321745 Regulation of Whrn 1 0.42 0.14 0
99 INT175837 Negative_regulation of USH2A 1 0.01 0 0
100 INT286398 Positive_regulation of Transcription of Dock4 1 0.46 0 0
101 INT321732 Localization of Whrn 1 0.66 0.08 0
102 INT170301 Negative_regulation of Negative_regulation of Ido1 1 0.36 0.32 0
103 INT246977 Positive_regulation of Gene_expression of USH2A 1 0.01 0 0
104 INT170310 Transcription of Ido1 1 0.61 0.52 0
105 INT150247 Transcription of Ido1 1 0.10 0 0
106 INT321749 Regulation of Myo15 1 0.37 0.14 0
107 INT321744 Negative_regulation of Whrn 1 0.40 0.13 0
108 INT150249 Negative_regulation of Transcription of Ido1 1 0.08 0 0
109 INT244265 Binding of USH2A 1 0.02 0.06 0
110 INT286408 Transcription of Dock4 1 0.66 0 0
111 INT321757 Negative_regulation of Myo15 1 0.31 0.13 0
112 INT321736 Gene_expression of Myo15 1 0.49 0 0
113 INT321752 Localization of Myo15 1 0.66 0.16 0
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