GO:0032430

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Name positive regulation of phospholipase A2 activity
Categary Process
Go Slim No
Go Link GO:0032430
Unique Molecular Interactions 42
Total Molecular Interactions 65
Total Single Events 429
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of phospholipase A2 activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of phospholipase A2 activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
2 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
3 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
4 INT259776 Fbn2 Regulation of Negative_regulation of Agtr1a 1 0.00 1.42 0.66
5 INT259768 Positive_regulation of Agtr1a Regulation of Etf1 1 0.00 1.32 0.62
6 INT79809 Binding of Agtr1a and Adra1a 1 0.02 0.23 0.53
7 INT182489 Gene_expression of AGTR2 Positive_regulation of Gene_expression of AGTR1 1 0.26 0.92 0.4
8 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39
9 INT278932 Binding of Agtr1a and H3 1 0.00 0 0.39
10 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34
11 INT330121 Agtr1a Positive_regulation of Gene_expression of Bdkrb1 1 0.05 0.68 0.34
12 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32
13 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
14 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28
15 INT297257 Agtr1a Positive_regulation of Agtr2 1 0.27 0.59 0.22
16 INT229360 Agt Positive_regulation of Agtr1a 2 0.48 1.26 0.2
17 INT230749 Crp Regulation of Agtr1a 1 0.07 1.33 0.19
18 INT224086 Binding of Agtr1a and Hspa8 1 0.00 0.1 0.19
19 INT224126 Binding of Hspa8 and Agtr1a 1 0.00 0.09 0.17
20 INT352290 Binding of Agtr1a and P2ry1 1 0.00 0 0.16
21 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14
22 INT293119 Agtr1a Regulation of Positive_regulation of Crh 1 0.12 0.37 0.14
23 INT293123 Agtr1a Regulation of Negative_regulation of Agt 1 0.14 0.25 0.14
24 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13
25 INT110176 Nts Regulation of Negative_regulation of Agtr1a 1 0.24 0.09 0.12
26 INT229359 Agt Positive_regulation of Binding of Agtr1a 1 0.25 0.9 0.12
27 INT336990 Binding of AGTR1 and BDKRB2 1 0.03 0 0.1
28 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09
29 INT279707 Positive_regulation of AGTR1 Regulation of TYRP1 1 0.00 0 0.09
30 INT279706 Positive_regulation of AGTR1 Regulation of TRPC6 1 0.00 0 0.09
31 INT249994 Binding of Agtr1a and Igkv4-55 1 0.01 0.38 0.08
32 INT281900 Positive_regulation of Binding of AGT and AGTR1 1 0.12 0.16 0.07
33 INT200641 Binding of ACE and Agtr1a 1 0.12 0.92 0.06
34 INT281909 Binding of AGT and AGTR1 1 0.09 0.16 0.06
35 INT336132 Binding of AGTR1 and ANG 1 0.00 0.38 0.05
36 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04
37 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0
38 INT340504 Agtr1a Negative_regulation of Phosphorylation of Pik3cb 1 0.06 1.16 0
39 INT229362 Negative_regulation of Agtr1a Positive_regulation of Positive_regulation of Agtr2 1 0.05 1 0
40 INT333044 Positive_regulation of Binding of AGTR1 and Trpv4 1 0.48 0 0
41 INT333045 Binding of AGTR1 and Gopc 1 0.05 0 0
42 INT333043 Binding of AGTR1 and Trpv4 1 0.50 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of phospholipase A2 activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of phospholipase A2 activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79703 Gene_expression of Agtr1a 46 0.76 14.18 13.77
2 INT53038 Positive_regulation of Agtr1a 35 0.67 23.76 11.68
3 INT10982 Negative_regulation of Agtr1a 42 0.58 22.42 10.29
4 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27
5 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29
6 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15
7 INT53040 Binding of Agtr1a 22 0.47 7.36 4.15
8 INT111195 Negative_regulation of Gene_expression of Agtr1a 7 0.58 3.2 3.16
9 INT63418 Regulation of Agtr1a 8 0.44 3.67 2.43
10 INT182505 Positive_regulation of Gene_expression of AGTR1 12 0.65 13.18 1.77
11 INT182514 Binding of AGTR1 18 0.47 13.35 1.48
12 INT182511 Regulation of AGTR1 7 0.44 8.25 1.4
13 INT83553 Positive_regulation of Positive_regulation of Agtr1a 3 0.59 4.12 1.37
14 INT148072 Gene_expression of Agtr1a 5 0.75 9.41 1.13
15 INT182512 Positive_regulation of Positive_regulation of AGTR1 5 0.47 4.88 0.97
16 INT229710 Localization of Agtr1a 3 0.60 0.57 0.84
17 INT102894 Localization of AGTR1 5 0.73 1.75 0.74
18 INT111196 Negative_regulation of Negative_regulation of Agtr1a 2 0.42 0.49 0.65
19 INT267971 Regulation of Localization of AGTR1 1 0.16 1.46 0.57
20 INT159150 Negative_regulation of Positive_regulation of Agtr1a 1 0.38 0.72 0.56
21 INT107385 Regulation of Negative_regulation of AGTR1 2 0.15 1.26 0.42
22 INT182507 Negative_regulation of Gene_expression of AGTR1 1 0.40 1.13 0.4
23 INT330125 Transcription of AGTR1 1 0.52 1.29 0.39
24 INT224111 Phosphorylation of Agtr1a 1 0.01 0 0.35
25 INT102889 Positive_regulation of Localization of AGTR1 3 0.38 0.43 0.34
26 INT263255 Negative_regulation of Negative_regulation of AGTR1 2 0.30 2.88 0.25
27 INT63417 Regulation of Negative_regulation of Agtr1a 1 0.26 0.1 0.25
28 INT247022 Transcription of Agtr1a 2 0.46 1.47 0.21
29 INT230740 Regulation of Agtr1a 2 0.15 3.5 0.19
30 INT209796 Positive_regulation of Agtr1a 1 0.15 0.56 0.15
31 INT288916 Negative_regulation of Positive_regulation of AGTR1 2 0.44 1.2 0.13
32 INT355657 Negative_regulation of Transcription of Agtr1a 1 0.38 1.17 0.13
33 INT355655 Regulation of Transcription of Agtr1a 1 0.29 1.15 0.13
34 INT99725 Negative_regulation of Agtr1a 5 0.57 1.03 0.12
35 INT229356 Negative_regulation of Binding of Agtr1a 1 0.36 0.89 0.12
36 INT242222 Positive_regulation of Negative_regulation of AGTR1 1 0.35 1.77 0.1
37 INT247024 Positive_regulation of Transcription of Agtr1a 1 0.19 0.33 0.09
38 INT209797 Regulation of Positive_regulation of Agtr1a 1 0.10 0.29 0.08
39 INT333041 Regulation of Positive_regulation of AGTR1 1 0.44 0 0.07
40 INT182487 Positive_regulation of Gene_expression of Agtr1a 2 0.19 1.32 0.04
41 INT179198 Regulation of Gene_expression of AGTR1 2 0.25 2.04 0.04
42 INT288912 Protein_catabolism of AGTR1 1 0.66 0.29 0
43 INT333040 Regulation of Binding of AGTR1 1 0.44 0 0
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