GO:0032435

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Name negative regulation of proteasomal ubiquitin-dependent protein catabolic process
Categary Process
Go Slim No
Go Link GO:0032435
Unique Molecular Interactions 62
Total Molecular Interactions 82
Total Single Events 500
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of proteasomal ubiquitin-dependent protein catabolic process. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of proteasomal ubiquitin-dependent protein catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38
2 INT4915 Binding of Tac2 and Gipc1 1 0.01 0 0.74
3 INT281083 Binding of Gria1 and Gipc1 1 0.01 0 0.65
4 INT165844 Binding of ATF4 and HSP90AB1 1 0.15 0.34 0.61
5 INT111184 Binding of GIPC1 and CHCHD8 1 0.00 0 0.59
6 INT77394 Binding of ARRB1 and GIPC1 1 0.01 0 0.56
7 INT117589 Binding of C5AR1 and GIPC1 1 0.10 0.39 0.34
8 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33
9 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
10 INT123194 Bmp6 Positive_regulation of TAF9 1 0.18 0.61 0.14
11 INT123193 Bmp6 Positive_regulation of Negative_regulation of TAF9 1 0.18 0.61 0.14
12 INT81789 Binding of MC1R and GIPC1 1 0.01 0 0.13
13 INT81786 Binding of AGRP and GIPC1 1 0.01 0 0.13
14 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
15 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
16 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
17 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
18 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
19 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
20 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
21 INT129331 Binding of Trpv1 and Gipc1 1 0.01 0 0.03
22 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
23 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
24 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
25 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
26 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
27 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
28 INT220456 Binding of VCAN and BAG6 1 0.01 3.46 0
29 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
30 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
31 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
32 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
33 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
34 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
35 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
36 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
37 INT252900 PTTG1 Regulation of Gene_expression of TAF9 1 0.20 0.84 0
38 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
39 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
40 INT220455 BAG6 Regulation of INCENP 1 0.00 0.32 0
41 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
42 INT220460 VEGFA Regulation of BAG6 1 0.02 1.28 0
43 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
44 INT252893 PTTG1 Positive_regulation of Gene_expression of TAF9 1 0.21 0.9 0
45 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
46 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
47 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
48 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
49 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
50 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of proteasomal ubiquitin-dependent protein catabolic process. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of proteasomal ubiquitin-dependent protein catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68
2 INT252999 Gene_expression of TAF9 12 0.75 12.65 2.92
3 INT211733 Phosphorylation of Gipc1 2 0.01 0 2.68
4 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16
5 INT262317 Binding of TAF9 7 0.31 9.67 2.15
6 INT161978 Positive_regulation of Localization of GIPC1 1 0.19 1.98 2.12
7 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
8 INT161979 Positive_regulation of Gene_expression of GIPC1 1 0.19 1.96 1.93
9 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
10 INT42277 Gene_expression of GIPC1 6 0.25 2.06 1.61
11 INT111186 Positive_regulation of GIPC1 4 0.67 1.44 1.46
12 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
13 INT220465 Binding of BAG6 7 0.30 6.41 1.07
14 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
15 INT59995 Localization of GIPC1 2 0.28 0.66 0.87
16 INT165847 Positive_regulation of HSP90AB1 1 0.60 0.31 0.6
17 INT165849 Protein_catabolism of HSP90AB1 1 0.56 0.28 0.56
18 INT77397 Phosphorylation of GIPC1 1 0.01 0 0.56
19 INT323004 Transcription of TAF9 1 0.05 0.79 0.54
20 INT52920 Phosphorylation of Gipc1 1 0.04 0 0.5
21 INT206484 Localization of Shh 2 0.75 1.14 0.46
22 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
23 INT322997 Localization of TAF9 1 0.05 1.2 0.4
24 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
25 INT46545 Binding of Gipc1 2 0.02 0 0.38
26 INT119612 Positive_regulation of Gipc1 1 0.01 0 0.35
27 INT252969 Positive_regulation of Gene_expression of TAF9 5 0.67 5.22 0.32
28 INT129812 Gene_expression of HSP90AB1 1 0.75 0.72 0.27
29 INT42278 Binding of GIPC1 3 0.03 0.33 0.26
30 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
31 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
32 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
33 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
34 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
35 INT253190 Localization of Shh 2 0.77 1.06 0.13
36 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
37 INT220472 Gene_expression of BAG6 1 0.11 13.93 0.12
38 INT40116 Regulation of Gipc1 1 0.01 0 0.09
39 INT270442 Transcription of Shh 1 0.53 0.25 0.09
40 INT213515 Binding of Shh 8 0.37 1.92 0.08
41 INT252991 Regulation of TAF9 2 0.44 3.54 0.08
42 INT270453 Regulation of Shh 1 0.27 0.83 0.08
43 INT263690 Negative_regulation of Gipc1 1 0.01 0 0.08
44 INT205973 Binding of SHH 3 0.35 1.03 0.07
45 INT256862 Regulation of Shh 1 0.25 0 0.07
46 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
47 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
48 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
49 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
50 INT253181 Transcription of Shh 1 0.68 0.54 0.03
51 INT220466 Regulation of BAG6 1 0.04 1.58 0
52 INT175049 Gene_expression of Gipc1 1 0.07 0.07 0
53 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
54 INT293680 Positive_regulation of Localization of HSP90AB1 1 0.45 0 0
55 INT220467 Positive_regulation of Gene_expression of BAG6 1 0.07 1.47 0
56 INT293675 Localization of HSP90AB1 1 0.68 0 0
57 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
58 INT151246 Regulation of GIPC1 1 0.01 0.22 0
59 INT290929 Binding of Shh 1 0.31 0.1 0
60 INT252984 Regulation of Gene_expression of TAF9 1 0.26 0.99 0
61 INT220468 Positive_regulation of Binding of BAG6 1 0.07 1.28 0
62 INT260516 Localization of Gipc1 1 0.01 0.83 0
63 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
64 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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