GO:0032444

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Name activin responsive factor complex
Categary Component
Go Slim No
Go Link GO:0032444
Unique Molecular Interactions 33
Total Molecular Interactions 33
Total Single Events 365
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for activin responsive factor complex. They are ordered first by their pain relevance and then by number of times they were reported for activin responsive factor complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137023 Gene_expression of SMAD2 Negative_regulation of Gene_expression of Acta2 1 0.00 0.43 0.29
2 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
3 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
4 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12
5 INT316823 Sparc Positive_regulation of Phosphorylation of Smad2 1 0.44 0.49 0.1
6 INT311906 Binding of Smad4 and Insrr 1 0.00 0.18 0.06
7 INT353284 Prdx2 Negative_regulation of Gene_expression of Smad2 1 0.16 0.07 0.05
8 INT353290 Binding of Smad2 and Smad4 1 0.20 0.08 0.04
9 INT353294 Binding of Smad2 and Smad3 1 0.15 0.08 0.04
10 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04
11 INT353289 Prdx2 Negative_regulation of Positive_regulation of Smad2 1 0.18 0.17 0.04
12 INT353293 Prdx2 Negative_regulation of Localization of Smad2 1 0.16 0 0.04
13 INT311904 Smad2 Positive_regulation of Gene_expression of Smad1 1 0.13 0.44 0.03
14 INT319218 Bmpr2 Negative_regulation of Smad2 1 0.17 0.12 0.03
15 INT353286 Prdx2 Positive_regulation of Phosphorylation of Smad2 1 0.24 0.06 0.03
16 INT280263 Binding of Smad4 and Proc 1 0.00 1.26 0.03
17 INT277927 WIF1 Negative_regulation of SMAD4 1 0.23 0.37 0
18 INT269915 Binding of Smad2 and Sox17 1 0.21 0.07 0
19 INT218669 Olr811 Negative_regulation of Phosphorylation of Smad2 1 0.01 0.18 0
20 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0
21 INT269936 Smad2 Positive_regulation of Cdkn2b 1 0.15 0.07 0
22 INT268341 SMAD2 Positive_regulation of SMAD4 1 0.31 0.56 0
23 INT337914 sb Negative_regulation of Phosphorylation of Smad2 1 0.00 0.13 0
24 INT337918 sb Positive_regulation of Negative_regulation of Smad2 1 0.00 0.15 0
25 INT218670 Olr811 Regulation of Phosphorylation of Smad2 1 0.00 0.33 0
26 INT269938 Smad2 Positive_regulation of Tpt1 1 0.14 0.07 0
27 INT268344 SMAD3 Positive_regulation of SMAD4 1 0.17 0.56 0
28 INT172981 PAN3 Negative_regulation of SMAD4 1 0.01 0.98 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for activin responsive factor complex. They are ordered first by their pain relevance and then by number of times they were reported in activin responsive factor complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
2 INT127113 Positive_regulation of Phosphorylation of Smad2 1 0.68 2.38 2.51
3 INT194504 Gene_expression of Smad2 27 0.65 7.45 2.25
4 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
5 INT127115 Regulation of Phosphorylation of Smad2 1 0.60 1.74 1.53
6 INT255251 Negative_regulation of Smad2 12 0.32 5.69 1.44
7 INT129619 Phosphorylation of Smad2 34 0.61 11.6 1.34
8 INT218696 Negative_regulation of Phosphorylation of Smad2 3 0.42 4.36 0.92
9 INT267095 Regulation of Gene_expression of Smad2 3 0.44 1.77 0.8
10 INT137007 Gene_expression of SMAD2 6 0.75 2.53 0.75
11 INT265318 Negative_regulation of Gene_expression of Smad2 8 0.26 2.16 0.72
12 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
13 INT269896 Positive_regulation of Gene_expression of Smad2 9 0.40 2.15 0.69
14 INT137009 Negative_regulation of Gene_expression of SMAD2 4 0.42 1.76 0.66
15 INT268377 Phosphorylation of SMAD2 7 0.80 0.85 0.65
16 INT302664 Positive_regulation of SMAD2 2 0.49 0.85 0.64
17 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
18 INT158889 Gene_expression of Smad2 5 0.65 1.25 0.51
19 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43
20 INT117564 Gene_expression of SMAD4 12 0.71 8.7 0.37
21 INT92100 Binding of Smad4 5 0.31 2.23 0.3
22 INT129908 Positive_regulation of Smad2 5 0.45 2.13 0.3
23 INT137008 Positive_regulation of Gene_expression of SMAD2 2 0.49 0.51 0.3
24 INT224877 Positive_regulation of Gene_expression of Smad2 1 0.12 0.16 0.29
25 INT172978 Negative_regulation of SMAD2 4 0.42 0.89 0.27
26 INT129907 Regulation of Smad2 1 0.40 0.87 0.23
27 INT265311 Localization of Smad2 5 0.50 1.57 0.21
28 INT265334 Regulation of Phosphorylation of Smad2 2 0.17 0.96 0.2
29 INT277935 Binding of SMAD4 4 0.28 1.12 0.17
30 INT268365 Binding of SMAD2 2 0.47 0.56 0.17
31 INT139977 Regulation of Smad4 1 0.16 1.41 0.15
32 INT135490 Localization of Smad2 1 0.51 0.08 0.14
33 INT158893 Negative_regulation of Gene_expression of Smad2 1 0.30 0.13 0.13
34 INT129616 Negative_regulation of Phosphorylation of Smad2 4 0.38 0.78 0.12
35 INT311892 Regulation of Positive_regulation of Smad2 1 0.23 0.24 0.12
36 INT325505 Transcription of Smad2 1 0.67 0.16 0.09
37 INT325510 Transcription of Smad4 1 0.67 0.16 0.09
38 INT254790 Localization of Smad4 2 0.37 0.54 0.06
39 INT254814 Positive_regulation of Phosphorylation of Smad2 7 0.33 3.74 0.04
40 INT337908 Binding of Smad2 3 0.24 1.06 0.04
41 INT353261 Negative_regulation of Localization of Smad2 1 0.33 0 0.04
42 INT334291 Positive_regulation of Gene_expression of SMAD4 1 0.18 0 0.04
43 INT353263 Positive_regulation of Localization of Smad2 1 0.33 0.15 0.04
44 INT268360 Positive_regulation of SMAD4 3 0.55 1.55 0.03
45 INT254799 Transcription of Smad2 1 0.19 0.52 0.03
46 INT353266 Negative_regulation of Negative_regulation of Smad2 1 0.28 0 0.03
47 INT296618 Negative_regulation of Smad2 1 0.37 1.42 0.03
48 INT117563 Negative_regulation of Gene_expression of SMAD4 6 0.54 3.87 0
49 INT268378 Positive_regulation of Phosphorylation of SMAD2 3 0.67 1.22 0
50 INT271411 Positive_regulation of Positive_regulation of Smad2 2 0.45 0.9 0
51 INT334327 Regulation of SMAD4 2 0.35 1.73 0
52 INT268368 Transcription of SMAD4 1 0.54 1.7 0
53 INT296615 Positive_regulation of Smad2 1 0.50 1.51 0
54 INT173000 Negative_regulation of Localization of SMAD4 1 0.22 0.98 0
55 INT173008 Localization of SMAD4 1 0.38 0.97 0
56 INT334289 Regulation of Binding of SMAD4 1 0.16 0 0
57 INT334288 Regulation of Negative_regulation of SMAD4 1 0.16 0 0
58 INT228250 Positive_regulation of Smad4 1 0.45 1.93 0
59 INT295579 Negative_regulation of Phosphorylation of SMAD2 1 0.42 0.08 0
60 INT228247 Regulation of Positive_regulation of Smad4 1 0.26 0.97 0
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