GO:0032481

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Name positive regulation of type I interferon production
Categary Process
Go Slim No
Go Link GO:0032481
Unique Molecular Interactions 46
Total Molecular Interactions 63
Total Single Events 169
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of type I interferon production. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of type I interferon production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83
2 INT282665 Binding of Gfap and Ticam1 1 0.01 0 0.69
3 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56
4 INT158599 Tlr3 Positive_regulation of Binding of Fas 1 0.55 0.86 0.48
5 INT296795 Binding of Tlr9 and Tlr3 2 0.22 1.29 0.45
6 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35
7 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33
8 INT306323 Tlr4 Positive_regulation of Ticam1 3 0.25 0.55 0.3
9 INT324873 Binding of Jun and Tlr3 1 0.01 1.54 0.22
10 INT350006 Tlr4 Regulation of Positive_regulation of Tlr3 1 0.41 0.17 0.21
11 INT350005 Tlr3 Positive_regulation of Il17rb 1 0.09 0.32 0.21
12 INT343837 TICAM1 Positive_regulation of IRF3 1 0.03 0.19 0.19
13 INT343831 TICAM1 Positive_regulation of Gene_expression of TLR4 1 0.11 0.19 0.19
14 INT339505 Tlr3 Positive_regulation of Eif2ak2 1 0.14 0.09 0.19
15 INT343852 Binding of TRAF1 and TICAM1 1 0.03 0.19 0.17
16 INT343850 Binding of TRAF4 and TICAM1 1 0.03 0.19 0.17
17 INT343915 Binding of Traf1 and TICAM1 1 0.08 0.19 0.17
18 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15
19 INT324831 Binding of TRIM63 and Ticam1 1 0.01 0.09 0.12
20 INT254229 Binding of Ticam1 and Positive_regulation of Binding of IFNA1 1 0.02 0.3 0.12
21 INT254207 Ticam1 Positive_regulation of Ik 1 0.00 0.14 0.12
22 INT254227 Binding of Ripk1 and Ticam1 3 0.07 0.18 0.11
23 INT254215 Binding of Tlr4 and Ticam1 2 0.09 0.76 0.11
24 INT334264 Binding of Gtf3a and Ticam1 1 0.00 0.18 0.11
25 INT183702 Binding of Tlr3 and Pilra 1 0.02 0.64 0.11
26 INT254220 Binding of Ticam1 and Sarm1 1 0.09 0.22 0.11
27 INT183694 Ducm1 Positive_regulation of Gene_expression of Tlr3 1 0.03 0.23 0.11
28 INT324869 Binding of Jun and Ticam1 1 0.01 0.76 0.11
29 INT324870 Binding of Ticam1 and Tlr3 1 0.03 0.76 0.11
30 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1
31 INT343845 TICAM1 Positive_regulation of TIRAP 1 0.05 0.25 0.09
32 INT254223 Tlr3 Positive_regulation of Myd88 1 0.16 0.23 0.08
33 INT346499 Mal Positive_regulation of TICAM1 1 0.06 0.66 0.07
34 INT346449 TICAM1 Positive_regulation of TBK1 1 0.01 0.45 0.06
35 INT346454 TICAM1 Positive_regulation of IKBKE 1 0.01 0.45 0.06
36 INT350478 Tirap Regulation of Ticam1 1 0.07 0.06 0.05
37 INT329045 Binding of Unc93b1 and Tlr3 1 0.03 0.7 0.05
38 INT350800 Binding of TLR3 and TICAM1 1 0.01 0 0.04
39 INT348028 Binding of Traf3 and Ticam1 1 0.01 0.56 0.03
40 INT284563 Tlr3 Positive_regulation of Mat1a 1 0.22 2.43 0
41 INT348015 Binding of Tlr4 and Tlr3 1 0.19 0 0
42 INT343842 Binding of TRAM1 and TICAM1 1 0.01 0.12 0
43 INT343824 Binding of TICAM1 and TICAM2 1 0.03 0.12 0
44 INT284566 Tlr3 Positive_regulation of Mthfd1 1 0.17 2.43 0
45 INT254231 Binding of TRAM1 and Ticam1 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of type I interferon production. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of type I interferon production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54
2 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07
3 INT158596 Binding of Tlr3 24 0.47 11.66 3.69
4 INT134919 Binding of Ticam1 6 0.18 1.12 1.94
5 INT150730 Regulation of Tlr3 2 0.45 6.51 1.37
6 INT150729 Negative_regulation of Tlr3 3 0.43 3.26 1.14
7 INT288489 Transcription of Tlr3 1 0.51 3.85 1.05
8 INT134917 Localization of Ticam1 2 0.51 0.6 0.99
9 INT288483 Gene_expression of Tlr3 8 0.72 4.51 0.97
10 INT134912 Positive_regulation of Localization of Ticam1 1 0.24 0.32 0.87
11 INT255974 Transcription of Tlr3 10 0.49 6.11 0.7
12 INT288485 Regulation of Transcription of Tlr3 1 0.20 0.85 0.61
13 INT254177 Positive_regulation of Positive_regulation of Tlr3 3 0.41 2.06 0.58
14 INT183685 Positive_regulation of Gene_expression of Tlr3 4 0.61 1.5 0.53
15 INT237905 Positive_regulation of Binding of Tlr3 1 0.30 0.79 0.42
16 INT183680 Localization of Tlr3 6 0.71 1.69 0.39
17 INT250167 Negative_regulation of Ticam1 3 0.29 2.03 0.37
18 INT254195 Gene_expression of Ticam1 3 0.29 0.46 0.24
19 INT254194 Regulation of Positive_regulation of Tlr3 2 0.52 0.79 0.19
20 INT288491 Positive_regulation of Transcription of Tlr3 1 0.37 1.85 0.19
21 INT324768 Positive_regulation of Ticam1 2 0.16 0.14 0.18
22 INT336418 Negative_regulation of Binding of Tlr3 1 0.36 0.59 0.16
23 INT324781 Protein_catabolism of Ticam1 1 0.27 0.74 0.15
24 INT254190 Positive_regulation of Binding of Ticam1 1 0.22 0.32 0.15
25 INT255970 Regulation of Transcription of Tlr3 1 0.24 0.89 0.09
26 INT329066 Positive_regulation of Gene_expression of Tlr3 1 0.43 1.12 0.08
27 INT228376 Binding of Tlr3 2 0.45 2.2 0.07
28 INT254184 Positive_regulation of Gene_expression of Ticam1 1 0.22 0.11 0.06
29 INT329051 Positive_regulation of Tlr3 1 0.65 0.33 0.04
30 INT320335 Positive_regulation of Transcription of Tlr3 1 0.43 0.13 0.03
31 INT350784 Positive_regulation of TICAM1 1 0.05 0 0.03
32 INT329818 Binding of TICAM1 2 0.07 0.12 0
33 INT260426 Regulation of Gene_expression of Tlr3 1 0.23 0.77 0
34 INT254192 Regulation of Binding of Ticam1 1 0.20 0 0
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