GO:0032494

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Name response to peptidoglycan
Categary Process
Go Slim No
Go Link GO:0032494
Unique Molecular Interactions 772
Total Molecular Interactions 1199
Total Single Events 10362
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to peptidoglycan. They are ordered first by their pain relevance and then by number of times they were reported for response to peptidoglycan. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
2 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
3 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
4 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
5 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
6 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
7 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
8 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
9 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
10 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
11 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
12 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
13 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
14 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
15 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
16 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
17 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
18 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
19 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
20 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
21 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
22 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
23 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
24 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
25 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
26 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
27 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
28 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
29 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
30 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
31 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
32 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
33 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
34 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
35 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
36 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
37 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
38 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
39 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
40 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
41 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
42 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
43 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
44 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
45 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
46 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
47 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
48 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
49 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
50 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
51 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
52 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
53 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
54 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
55 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
56 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
57 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
58 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
59 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
60 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
61 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
62 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
63 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
64 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
65 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
66 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
67 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
68 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
69 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
70 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
71 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
72 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89
73 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
74 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
75 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
76 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
77 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
78 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
79 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
80 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
81 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
82 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
83 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
84 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
85 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79
86 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
87 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
88 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
89 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
90 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
91 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73
92 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
93 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
94 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
95 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
96 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
97 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
98 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
99 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
100 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
101 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
102 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
103 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
104 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
105 INT316690 Binding of Myd88 and Il1 2 0.06 1.75 0.66
106 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
107 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
108 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
109 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
110 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
111 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
112 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63
113 INT71526 Regulation of Il1b Positive_regulation of Il6 1 0.17 0.14 0.62
114 INT264335 Binding of IL-17 and Positive_regulation of Localization of Il6 1 0.13 1.62 0.62
115 INT71527 Negative_regulation of OPRD1 Negative_regulation of Positive_regulation of Il6 1 0.00 0.15 0.62
116 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
117 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
118 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
119 INT71525 Oprd1 Regulation of Il6 1 0.16 0.19 0.6
120 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6
121 INT91699 Il6 Regulation of Gene_expression of Oprl1 1 0.06 0 0.6
122 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
123 INT168416 MIR146A Regulation of Irak1 1 0.24 0.99 0.59
124 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
125 INT151461 Olr1745 Negative_regulation of Gene_expression of Il6 1 0.03 0.81 0.57
126 INT142312 Lalba Negative_regulation of Localization of Il6 1 0.23 0.73 0.57
127 INT231712 GAGE2C Regulation of Transcription of IL6 1 0.01 1.01 0.57
128 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
129 INT307016 IGKV1-17 Positive_regulation of Gene_expression of IL6 1 0.00 1.01 0.56
130 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56
131 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54
132 INT231711 GPR174 Regulation of Transcription of IL6 1 0.01 0.96 0.54
133 INT137016 Il6 Positive_regulation of Gene_expression of Acta2 1 0.01 0.75 0.54
134 INT100597 Regulation of RPL21P132 Positive_regulation of IL6 1 0.01 0.45 0.53
135 INT285940 Binding of IL6 and IL17A 1 0.11 1.42 0.53
136 INT50935 Mtr Regulation of Gene_expression of Il6 1 0.00 0 0.53
137 INT310532 IL6 Regulation of Regulation of TNF 1 0.34 0.73 0.52
138 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
139 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51
140 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51
141 INT348322 Il6 Positive_regulation of Localization of Crp 1 0.06 3.51 0.51
142 INT62446 Il6 Positive_regulation of Crh 1 0.22 0.05 0.5
143 INT64720 Regulation of IL1B Positive_regulation of IL6 1 0.36 0.65 0.5
144 INT97801 Gm5564 Regulation of Gene_expression of IL6 1 0.00 0.07 0.5
145 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
146 INT195220 Binding of CPB2 and IL6 1 0.04 0.5 0.49
147 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
148 INT100595 RPL21P132 Positive_regulation of IL6 1 0.01 0.43 0.49
149 INT61616 TNF Negative_regulation of Gene_expression of IL6 1 0.37 0.33 0.49
150 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48
151 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
152 INT286352 IL6 Positive_regulation of Gene_expression of IL8 2 0.24 1.32 0.48
153 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48
154 INT155921 PARP1 Positive_regulation of Gene_expression of IL6 1 0.49 0.44 0.48
155 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48
156 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48
157 INT132448 MIR3607 Negative_regulation of IL6 1 0.01 2.45 0.48
158 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48
159 INT135589 CSF2 Regulation of IL6 1 0.08 1.27 0.48
160 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47
161 INT114754 Il6 Positive_regulation of Gene_expression of Crp 2 0.08 1.67 0.47
162 INT189151 MTNR1B Positive_regulation of Gene_expression of IL6 1 0.01 0.35 0.47
163 INT231340 INCENP Regulation of Gene_expression of IL6 1 0.01 1.09 0.47
164 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
165 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
166 INT138159 IL6 Positive_regulation of Gene_expression of Mmp3 1 0.00 0.23 0.46
167 INT280614 Il6 Regulation of Transcription of Irs1 1 0.26 0.4 0.46
168 INT67528 PTGER2 Positive_regulation of Gene_expression of IL6 2 0.10 1.38 0.45
169 INT67527 MRXS5 Positive_regulation of Gene_expression of IL6 1 0.21 1.5 0.45
170 INT224282 Binding of Bdnf and Il6 1 0.08 0.26 0.45
171 INT355568 MIF Positive_regulation of IL6 1 0.05 1.05 0.44
172 INT246023 IL6 Positive_regulation of SOCS2 1 0.18 0.99 0.43
173 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43
174 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
175 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43
176 INT51475 Binding of Il6 and Tnf 1 0.15 0.61 0.43
177 INT264326 IL-17 Positive_regulation of Gene_expression of Il6 1 0.13 0.83 0.43
178 INT169288 TRPV1 Positive_regulation of Localization of IL6 1 0.24 0 0.42
179 INT83913 Il1b Positive_regulation of Gene_expression of IL6 1 0.01 0.5 0.41
180 INT83916 Il1b Positive_regulation of IL6 1 0.02 0.5 0.41
181 INT100594 DCSTAMP Positive_regulation of Gene_expression of IL6 1 0.03 0.24 0.41
182 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41
183 INT339493 Binding of Irak1 and Irak3 1 0.02 0.17 0.41
184 INT100598 PRNP Positive_regulation of Gene_expression of IL6 1 0.40 0.23 0.4
185 INT343919 Hspa1a Positive_regulation of Gene_expression of IL6 1 0.02 1.17 0.4
186 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
187 INT330598 Binding of Il6 and Fig4 1 0.11 1.78 0.4
188 INT188336 IL6 Positive_regulation of Localization of POMC 1 0.01 0.83 0.4
189 INT294780 IL6 Positive_regulation of IL10 2 0.10 1.26 0.39
190 INT285746 IL6 Regulation of Localization of PRL 1 0.08 1.51 0.39
191 INT285749 IL6 Positive_regulation of Localization of PRL 1 0.08 1.51 0.39
192 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
193 INT140574 Ifnb1 Positive_regulation of Il6 1 0.05 0.9 0.39
194 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
195 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
196 INT203140 Binding of C5ar1 and C5 1 0.39 0.81 0.38
197 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
198 INT328819 Binding of Il6 and Jak1 1 0.08 0 0.38
199 INT328826 Binding of Il6 and TYK2 1 0.04 0 0.38
200 INT328818 Regulation of Il6 Positive_regulation of Stat3 1 0.04 0 0.38

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to peptidoglycan. They are ordered first by their pain relevance and then by number of times they were reported in response to peptidoglycan. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
3 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
4 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
5 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
6 INT12082 Localization of IL6 365 0.81 241.78 105.78
7 INT19511 Localization of Il6 212 0.81 118.17 67.67
8 INT10706 Regulation of Il6 150 0.62 93.23 62.34
9 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
10 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
11 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
12 INT9210 Regulation of IL6 166 0.62 125.61 49.95
13 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
14 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
15 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
16 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
17 INT86437 Binding of IL6 154 0.48 121.22 29.3
18 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
19 INT51474 Binding of Il6 55 0.48 44.99 20.52
20 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
21 INT61626 Transcription of IL6 73 0.72 42.04 17.86
22 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
23 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
24 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
25 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
26 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
27 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
28 INT50933 Transcription of Il6 38 0.72 24.31 11.58
29 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
30 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
31 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67
32 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
33 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43
34 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
35 INT197491 Gene_expression of Myd88 32 0.74 14.59 5.29
36 INT174688 Binding of Tlr2 45 0.42 36.65 5.25
37 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
38 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18
39 INT142752 Positive_regulation of Myd88 26 0.66 12.07 4.4
40 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37
41 INT25503 Gene_expression of C5AR1 22 0.75 21.88 4.16
42 INT142754 Binding of Myd88 20 0.36 9.61 3.8
43 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
44 INT81403 Positive_regulation of Regulation of Il6 4 0.44 1.81 3.37
45 INT64715 Phosphorylation of Il6 7 0.81 4.24 3.36
46 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04
47 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
48 INT33219 Positive_regulation of C5AR1 14 0.67 7.75 2.74
49 INT45109 Binding of C5AR1 10 0.37 5.77 2.69
50 INT64714 Positive_regulation of Phosphorylation of Il6 4 0.50 3.22 2.67
51 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
52 INT204775 Regulation of Tlr2 21 0.41 13.6 2.18
53 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
54 INT145196 Gene_expression of Irak3 5 0.23 4.23 2.13
55 INT145195 Positive_regulation of Irak3 4 0.15 3.65 2.12
56 INT208890 Gene_expression of Irak1 7 0.65 2.42 1.87
57 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
58 INT155455 Negative_regulation of Phosphorylation of Il6 1 0.31 2.5 1.76
59 INT228195 Negative_regulation of Gene_expression of Tlr2 14 0.40 12.17 1.74
60 INT233975 Positive_regulation of Gene_expression of Myd88 7 0.66 4.17 1.65
61 INT98448 Regulation of Binding of Il6 3 0.39 2.6 1.46
62 INT77368 Regulation of Regulation of Il6 3 0.35 1.86 1.45
63 INT98449 Positive_regulation of Binding of Il6 3 0.44 2.96 1.44
64 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
65 INT174683 Transcription of Tlr2 12 0.58 5.95 1.4
66 INT246928 Negative_regulation of Myd88 12 0.38 6.16 1.3
67 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
68 INT221131 Localization of Tlr2 17 0.80 13.82 1.28
69 INT233970 Regulation of Myd88 7 0.45 5.2 1.28
70 INT190075 Regulation of Transcription of Il6 2 0.45 2.17 1.18
71 INT190804 Positive_regulation of Tlr2 6 0.66 3.7 1.16
72 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
73 INT17692 Negative_regulation of C5AR1 5 0.57 2.99 1.04
74 INT134260 Negative_regulation of Transcription of Il6 2 0.25 1.39 0.99
75 INT152021 Regulation of Negative_regulation of IL6 3 0.32 1.38 0.98
76 INT288493 Positive_regulation of Gene_expression of Tlr2 4 0.66 4.38 0.94
77 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92
78 INT153292 Localization of C5AR1 2 0.68 0.79 0.91
79 INT237858 Positive_regulation of MYD88 5 0.49 2.93 0.9
80 INT145760 Binding of Tlr2 5 0.46 3.59 0.89
81 INT250171 Localization of Myd88 4 0.72 1.95 0.88
82 INT254188 Positive_regulation of Irak1 7 0.44 3.46 0.87
83 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84
84 INT166126 Gene_expression of MYD88 5 0.54 2.67 0.84
85 INT264973 Binding of MYD88 4 0.35 1.2 0.74
86 INT224630 Positive_regulation of Positive_regulation of Tlr2 6 0.46 4.14 0.73
87 INT228188 Regulation of Gene_expression of Tlr2 5 0.45 6.96 0.71
88 INT158354 Negative_regulation of Binding of Il6 2 0.20 2.21 0.71
89 INT168411 Binding of Irak1 1 0.18 1.08 0.68
90 INT334226 Positive_regulation of Localization of Myd88 1 0.36 0.54 0.67
91 INT233973 Negative_regulation of Gene_expression of Myd88 4 0.38 1.32 0.61
92 INT323751 Gene_expression of IRAK1 3 0.44 1.33 0.6
93 INT264490 Regulation of Negative_regulation of Il6 2 0.23 1.18 0.6
94 INT188433 Negative_regulation of Binding of IL6 6 0.42 2.03 0.56
95 INT61025 Negative_regulation of Negative_regulation of Il6 3 0.43 1.15 0.56
96 INT334219 Phosphorylation of Irak1 6 0.73 1.21 0.55
97 INT234597 Negative_regulation of Positive_regulation of Tlr2 2 0.30 2.25 0.52
98 INT264963 Positive_regulation of Binding of MYD88 1 0.17 0.18 0.52
99 INT234587 Positive_regulation of Transcription of Tlr2 3 0.36 1.84 0.51
100 INT334230 Negative_regulation of Irak1 2 0.38 0.3 0.51
101 INT115189 Regulation of Phosphorylation of IL6 1 0.04 0 0.48
102 INT204781 Positive_regulation of Nod2 6 0.45 2.79 0.46
103 INT240020 Regulation of Binding of IL6 4 0.36 4.38 0.46
104 INT98447 Positive_regulation of Negative_regulation of Il6 1 0.44 0.75 0.45
105 INT323739 Regulation of IRAK1 3 0.23 1.73 0.43
106 INT270000 Localization of IRAK1 3 0.73 0.82 0.43
107 INT343891 Positive_regulation of Gene_expression of IRAK1 1 0.23 0.3 0.42
108 INT339480 Negative_regulation of Positive_regulation of Irak3 1 0.05 0.12 0.41
109 INT246422 Transcription of MYD88 2 0.52 0.77 0.38
110 INT334241 Binding of Irak1 1 0.43 1.09 0.38
111 INT203145 Binding of C5ar1 1 0.35 0.81 0.38
112 INT256056 Positive_regulation of Binding of Myd88 2 0.48 0.36 0.36
113 INT82552 Negative_regulation of Regulation of Il6 2 0.38 1.43 0.36
114 INT324756 Regulation of Irak1 5 0.40 0.87 0.35
115 INT203076 Positive_regulation of Positive_regulation of Myd88 1 0.19 0.65 0.32
116 INT203072 Positive_regulation of Myd88 1 0.19 0.65 0.32
117 INT143536 Protein_catabolism of Il6 2 0.69 1.89 0.31
118 INT288189 Negative_regulation of Negative_regulation of Tlr2 1 0.26 0.43 0.28
119 INT346895 Positive_regulation of Gene_expression of Nod2 1 0.33 0.74 0.28
120 INT197492 Regulation of Gene_expression of Myd88 2 0.39 1.95 0.27
121 INT288186 Regulation of Binding of Tlr2 2 0.32 1.72 0.26
122 INT224614 Regulation of Positive_regulation of Tlr2 1 0.13 0.56 0.26
123 INT346896 Binding of Nod2 1 0.21 0.72 0.26
124 INT298665 Positive_regulation of Protein_catabolism of IL6 1 0.09 2.03 0.25
125 INT25505 Protein_catabolism of C5AR1 2 0.64 1.29 0.24
126 INT145758 Regulation of Tlr2 3 0.43 0.94 0.23
127 INT145761 Negative_regulation of Tlr2 2 0.41 1.97 0.23
128 INT346899 Regulation of Positive_regulation of Nod2 1 0.18 0.75 0.22
129 INT242901 Regulation of Gene_expression of MYD88 2 0.18 0.19 0.19
130 INT242897 Positive_regulation of Gene_expression of MYD88 2 0.20 0.27 0.19
131 INT334224 Positive_regulation of Phosphorylation of Irak1 1 0.44 0.12 0.19
132 INT324780 Localization of Irak1 1 0.33 1.03 0.19
133 INT15992 Regulation of C5AR1 5 0.60 0.91 0.17
134 INT233971 Transcription of Myd88 2 0.60 1.01 0.17
135 INT66121 Negative_regulation of C5ar1 1 0.09 0 0.17
136 INT294633 Positive_regulation of Binding of Tlr2 1 0.44 0.42 0.16
137 INT145759 Regulation of Gene_expression of Tlr2 3 0.43 0.98 0.14
138 INT298988 Positive_regulation of Gene_expression of Irak1 2 0.44 0.25 0.14
139 INT188222 Positive_regulation of Regulation of IL6 2 0.29 0.51 0.13
140 INT301958 Positive_regulation of Regulation of Tlr2 1 0.21 0.32 0.13
141 INT53222 Regulation of Negative_regulation of C5AR1 1 0.26 0.61 0.13
142 INT298669 Negative_regulation of Protein_catabolism of IL6 1 0.08 1.02 0.13
143 INT323746 Phosphorylation of IRAK1 1 0.46 0.81 0.12
144 INT334237 Negative_regulation of Binding of Myd88 1 0.30 1.16 0.12
145 INT323732 Regulation of Gene_expression of IRAK1 1 0.26 0.82 0.12
146 INT306310 Positive_regulation of Positive_regulation of Myd88 1 0.38 0.41 0.12
147 INT242898 Regulation of MYD88 2 0.33 0.88 0.11
148 INT329055 Gene_expression of Myd88 1 0.72 1.18 0.11
149 INT329058 Positive_regulation of Transcription of Tlr2 1 0.48 0.62 0.11
150 INT346495 Positive_regulation of Irak1 1 0.45 0.33 0.11
151 INT335789 Negative_regulation of Transcription of IRAK1 1 0.22 0.45 0.11
152 INT335817 Transcription of IRAK1 1 0.35 0.45 0.11
153 INT329049 Transcription of Tlr2 1 0.68 0.62 0.11
154 INT74579 Positive_regulation of Gene_expression of C5AR1 2 0.67 5.57 0.1
155 INT335806 Negative_regulation of IRAK1 1 0.30 0.36 0.1
156 INT270150 Positive_regulation of Positive_regulation of Irak1 3 0.25 0.91 0.09
157 INT204777 Negative_regulation of Localization of Nod2 1 0.28 0.61 0.09
158 INT270154 Regulation of Positive_regulation of Irak1 1 0.19 0.48 0.09
159 INT334238 Positive_regulation of Binding of Irak1 1 0.44 0.14 0.09
160 INT255976 Regulation of Transcription of Tlr2 1 0.22 0.89 0.09
161 INT204779 Localization of Nod2 1 0.48 0.6 0.08
162 INT334227 Positive_regulation of Regulation of Myd88 1 0.36 0.63 0.08
163 INT334231 Positive_regulation of Regulation of Irak1 1 0.44 0.63 0.08
164 INT269821 Regulation of Localization of Tlr2 1 0.27 1.04 0.07
165 INT204770 Regulation of Nod2 1 0.29 0.66 0.07
166 INT329054 Negative_regulation of Gene_expression of Myd88 1 0.54 0.13 0.06
167 INT329067 Positive_regulation of Gene_expression of Myd88 1 0.64 0.12 0.05
168 INT334235 Negative_regulation of Binding of Irak1 1 0.38 0.33 0.04
169 INT246930 Negative_regulation of Transcription of Tlr2 1 0.36 0.92 0.04
170 INT346893 Negative_regulation of Gene_expression of Nod2 1 0.28 0.13 0.04
171 INT145757 Negative_regulation of Gene_expression of Tlr2 2 0.41 0.68 0.03
172 INT276939 Positive_regulation of Phosphorylation of Tlr2 1 0.46 0.6 0.03
173 INT276931 Phosphorylation of Tlr2 1 0.75 0.6 0.03
174 INT246929 Positive_regulation of Localization of Tlr2 2 0.42 0.26 0
175 INT246927 Negative_regulation of Binding of Tlr2 1 0.31 0 0
176 INT284053 Positive_regulation of Positive_regulation of Nod2 1 0.25 0.08 0
177 INT279567 Transcription of C5AR1 1 0.67 1.53 0
178 INT279583 Negative_regulation of Transcription of C5AR1 1 0.41 1.53 0
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