GO:0032496

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Name response to lipopolysaccharide
Categary Process
Go Slim No
Go Link GO:0032496
Unique Molecular Interactions 8168
Total Molecular Interactions 11652
Total Single Events 106480
Pain Genes Associated 302

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to lipopolysaccharide. They are ordered first by their pain relevance and then by number of times they were reported for response to lipopolysaccharide. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
3 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
4 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18
5 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
6 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
7 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
8 INT31439 Penk Positive_regulation of Localization of Prl 8 0.55 0.23 6.24
9 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
10 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
11 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87
12 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
13 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
14 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44
15 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96
16 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
17 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
18 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
19 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
20 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
21 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
22 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39
23 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29
24 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
25 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19
26 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18
27 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
28 INT31440 Penk Positive_regulation of Prl 7 0.76 0 4.1
29 INT2169 Penk Regulation of Localization of Prl 6 0.48 0 4.03
30 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
31 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
32 INT107801 Ugt1a5 Positive_regulation of Localization of Prl 3 0.76 1 3.9
33 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
34 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
35 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
36 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
37 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
38 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
39 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
40 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
41 INT64883 Ptger2 Positive_regulation of Ina 1 0.03 1.26 3.64
42 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
43 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
44 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
45 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
46 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
47 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
48 INT3434 Vip Positive_regulation of Localization of Prl 6 0.76 0.16 3.21
49 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
50 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
51 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
52 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
53 INT40660 Pdyn Positive_regulation of Localization of Prl 1 0.27 0 3.01
54 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
55 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96
56 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
57 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
58 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
59 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
60 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
61 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
62 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
63 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
64 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
65 INT91649 Binding of Lbp and SPECC1 1 0.12 2.88 2.78
66 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
67 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
68 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
69 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
70 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
71 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
72 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
73 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
74 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
75 INT212505 Binding of pr and Lbp 1 0.01 4.26 2.62
76 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
77 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
78 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
79 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
80 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54
81 INT104218 SCD Positive_regulation of CNR2 1 0.01 2.67 2.54
82 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53
83 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
84 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
85 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
86 INT143272 Binding of CNR1 and Gprasp1 1 0.01 0.17 2.42
87 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
88 INT318998 IFNA1 Positive_regulation of Localization of CXCL10 1 0.15 2.09 2.39
89 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
90 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
91 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
92 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
93 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
94 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
95 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
96 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
97 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
98 INT131257 ITIH4 Positive_regulation of Gene_expression of Nfkbia 1 0.23 1.41 2.3
99 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
100 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26
101 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
102 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
103 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24
104 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
105 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
106 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
107 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
108 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
109 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
110 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
111 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
112 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
113 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
114 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
115 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
116 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
117 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
118 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
119 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
120 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12
121 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
122 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
123 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
124 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
125 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
126 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
127 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
128 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
129 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
130 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
131 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
132 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
133 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
134 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
135 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
136 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
137 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
138 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
139 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
140 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
141 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
142 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
143 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
144 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
145 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
146 INT14991 SFTPA1 Positive_regulation of Localization of MPO 1 0.11 1.65 1.92
147 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92
148 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
149 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
150 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
151 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
152 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
153 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
154 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
155 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
156 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
157 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
158 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
159 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
160 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
161 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
162 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
163 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
164 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
165 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
166 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
167 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
168 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
169 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
170 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
171 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73
172 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
173 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
174 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71
175 INT119413 SEMA6A Positive_regulation of TNFRSF11A 1 0.10 2.48 1.7
176 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
177 INT30134 Binding of TPP1 and S100A9 1 0.13 0.74 1.69
178 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
179 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
180 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
181 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
182 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
183 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
184 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67
185 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
186 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
187 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
188 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
189 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
190 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65
191 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
192 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
193 INT169441 TAC1 Positive_regulation of Tac1 1 0.01 1.7 1.64
194 INT182563 Ptger2 Positive_regulation of Ptger1 1 0.22 1.4 1.64
195 INT147258 Binding of Tac1 and Penk 1 0.35 0 1.64
196 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
197 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
198 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
199 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62
200 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to lipopolysaccharide. They are ordered first by their pain relevance and then by number of times they were reported in response to lipopolysaccharide. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT158 Localization of Prl 2431 0.81 378.96 952.2
3 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
4 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
5 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82
6 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
7 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
8 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78
9 INT162 Regulation of Prl 794 0.62 165.01 322.24
10 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
11 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
12 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66
13 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
14 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
15 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
16 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
17 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
18 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
19 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
20 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
21 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
22 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
23 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24
24 INT528 Gene_expression of Prl 693 0.78 217.18 192.2
25 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
26 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
27 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
28 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8
29 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
30 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
31 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
32 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
33 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
34 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
35 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
36 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
37 INT1026 Binding of Lbp 207 0.48 150.96 119.16
38 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
39 INT7327 Regulation of Th 164 0.62 29.67 110.14
40 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34
41 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
42 INT12082 Localization of IL6 365 0.81 241.78 105.78
43 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
44 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
45 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
46 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
47 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
48 INT5587 Regulation of Fos 191 0.62 40.81 99.7
49 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
50 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
51 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
52 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49
53 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7
54 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
55 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
56 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
57 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
58 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
59 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71
60 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
61 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
62 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47
63 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
64 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
65 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
66 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
67 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
68 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
69 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
70 INT3034 Localization of Ngf 126 0.81 50.81 72.84
71 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68
72 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
73 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
74 INT6849 Localization of IL1B 229 0.81 112.56 69.63
75 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
76 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26
77 INT19511 Localization of Il6 212 0.81 118.17 67.67
78 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33
79 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
80 INT9664 Binding of LBP 127 0.48 94.9 63.42
81 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1
82 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84
83 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
84 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
85 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42
86 INT10706 Regulation of Il6 150 0.62 93.23 62.34
87 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
88 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
89 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
90 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
91 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
92 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74
93 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
94 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
95 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72
96 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59
97 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
98 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
99 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
100 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16
101 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
102 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
103 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
104 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
105 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
106 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
107 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
108 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
109 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75
110 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
111 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51
112 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
113 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
114 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
115 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14
116 INT9210 Regulation of IL6 166 0.62 125.61 49.95
117 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
118 INT1977 Negative_regulation of Positive_regulation of Prl 98 0.59 17.06 47.88
119 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
120 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05
121 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
122 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
123 INT4776 Localization of TAC1 82 0.78 16.89 45.21
124 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06
125 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
126 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
127 INT63383 Binding of Cnr1 77 0.48 22.28 44.61
128 INT19078 Binding of Ngf 78 0.48 31.03 44.33
129 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
130 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
131 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97
132 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
133 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78
134 INT9372 Negative_regulation of Lbp 86 0.58 46.54 41.71
135 INT350 Localization of Th 79 0.80 10.26 41.17
136 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49
137 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
138 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
139 INT49643 Gene_expression of Bdkrb1 39 0.78 46.49 40.21
140 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
141 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
142 INT16194 Binding of CNR1 82 0.48 20.75 39.59
143 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57
144 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
145 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03
146 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
147 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
148 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
149 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
150 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
151 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
152 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
153 INT12608 Regulation of CNR1 62 0.60 24.36 36.02
154 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36
155 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97
156 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55
157 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5
158 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39
159 INT7326 Transcription of Th 83 0.72 13.5 35.33
160 INT6484 Binding of IL1B 122 0.47 75.84 35.07
161 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
162 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52
163 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
164 INT17381 Gene_expression of Tbxa2r 146 0.78 65.01 34.15
165 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
166 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
167 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
168 INT50308 Binding of Cnr1 61 0.48 14.41 33.52
169 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
170 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23
171 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
172 INT4727 Regulation of TAC1 60 0.47 6.74 32.83
173 INT99610 Localization of MMP9 126 0.79 48.46 32.67
174 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
175 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
176 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26
177 INT6053 Transcription of Fos 107 0.72 20.97 31.88
178 INT9347 Localization of Il1b 58 0.81 26.13 31.53
179 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41
180 INT47764 Binding of Jun 106 0.48 22.62 31.39
181 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
182 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
183 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
184 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
185 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
186 INT6058 Localization of Fos 73 0.81 16.7 30.84
187 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46
188 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
189 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
190 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
191 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
192 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
193 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
194 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
195 INT86437 Binding of IL6 154 0.48 121.22 29.3
196 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
197 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58
198 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
199 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
200 INT116737 Localization of Mif 63 0.81 52.97 28.11
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