GO:0032593

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Name insulin-responsive compartment
Categary Component
Go Slim No
Go Link GO:0032593
Unique Molecular Interactions 52
Total Molecular Interactions 62
Total Single Events 585
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for insulin-responsive compartment. They are ordered first by their pain relevance and then by number of times they were reported for insulin-responsive compartment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16438 Atp6v0d2 Regulation of Localization of Lnpep 1 0.01 0 0.81
2 INT16435 Ubqln1 Regulation of Localization of Lnpep 1 0.01 0 0.81
3 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53
4 INT116610 Positive_regulation of Lnpep Regulation of Nos2 1 0.16 0.62 0.44
5 INT116608 Lnpep Regulation of Nos2 1 0.14 0.62 0.44
6 INT116613 Lnpep Negative_regulation of Gene_expression of BAX 1 0.42 0.62 0.43
7 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
8 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
9 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
10 INT116612 Lnpep Negative_regulation of BAX 1 0.42 0.62 0.42
11 INT116611 Lnpep Positive_regulation of Binding of Nos2 1 0.16 0.62 0.42
12 INT337412 AKT3 Negative_regulation of Localization of AKT2 1 0.09 0.5 0.32
13 INT337418 AKT2 Negative_regulation of Localization of AKT3 1 0.09 0.5 0.32
14 INT337414 AKT2 Negative_regulation of AKT1 1 0.10 0.5 0.32
15 INT141871 Binding of Nos3 and Slc2a4 1 0.25 0.51 0.28
16 INT45544 Ncapg2 Regulation of Localization of Lnpep 1 0.00 0 0.28
17 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
18 INT45541 Agt Positive_regulation of Lnpep 1 0.03 0 0.27
19 INT120975 Ins1 Positive_regulation of Gene_expression of Slc2a4 1 0.19 0.75 0.27
20 INT256028 Binding of Agt and Lnpep 1 0.19 1.16 0.24
21 INT160464 Binding of Mme and Lnpep 1 0.31 0.37 0.24
22 INT55300 Slc2a1 Regulation of Gene_expression of Slc2a4 1 0.41 0.41 0.19
23 INT55296 Slc2a4 Regulation of Ins1 1 0.17 0.41 0.19
24 INT55299 Slc2a4 Regulation of Gene_expression of Slc2a1 1 0.41 0.41 0.19
25 INT306261 AKT2 Negative_regulation of Phosphorylation of FOXO1 1 0.25 0.41 0.17
26 INT207109 F2 Positive_regulation of Phosphorylation of Akt2 1 0.08 0.25 0.12
27 INT207112 Sh2b2 Positive_regulation of Phosphorylation of Akt2 1 0.68 0.24 0.12
28 INT207115 Sh2b2 Positive_regulation of Akt2 1 0.49 0.24 0.12
29 INT126922 Ins1 Positive_regulation of Localization of Slc2a4 1 0.23 0.75 0.11
30 INT256023 Lnpep Regulation of Gene_expression of Agt 1 0.18 0.14 0.1
31 INT256022 Lnpep Regulation of Oxt 1 0.15 0.14 0.1
32 INT256029 Lnpep Regulation of Agt 1 0.18 0.14 0.1
33 INT256017 Lnpep Regulation of Avp 1 0.01 0.14 0.1
34 INT229333 Binding of Nr1h2 and Positive_regulation of Gene_expression of SLC2A4 1 0.02 0.62 0.07
35 INT249987 Agt Negative_regulation of Lnpep 1 0.11 0.53 0.07
36 INT55297 Gene_expression of Slc2a4 Positive_regulation of Ins1 1 0.19 0.36 0.06
37 INT238314 Pik3cb Negative_regulation of Localization of Slc2a4 1 0.06 0.25 0.05
38 INT329219 Ins1 Positive_regulation of Gene_expression of Slc2a4 1 0.04 0.93 0.05
39 INT352519 INS Positive_regulation of Localization of Slc2a4 1 0.07 0.97 0.03
40 INT348225 Glp1r Regulation of Localization of Slc2a4 1 0.36 0.66 0.03
41 INT348223 Glp1r Regulation of Positive_regulation of Slc2a4 1 0.26 0.66 0.03
42 INT348224 Glp1r Regulation of Slc2a4 1 0.26 0.66 0.03
43 INT268187 Rab4a Regulation of Rab22a 1 0.15 0.12 0
44 INT255752 hs Positive_regulation of Phosphorylation of Slc2a4 1 0.08 1.32 0
45 INT256016 Binding of Oxt and Lnpep 1 0.11 0.64 0
46 INT268191 Rab4a Regulation of Gene_expression of Prnp 1 0.23 0.22 0
47 INT249992 Binding of Lnpep and Igkv4-55 1 0.01 0.47 0
48 INT246787 Akt2 Positive_regulation of Phosphorylation of Tsc2 1 0.10 0.16 0
49 INT296959 NRIP1 Regulation of SLC2A4 1 0.22 0.54 0
50 INT200651 AKT2 Regulation of AKT1 1 0.31 0.21 0
51 INT268177 Rab4a Regulation of Prnp 1 0.14 0.22 0
52 INT255749 Ptch1 Positive_regulation of Phosphorylation of Slc2a4 1 0.15 1.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for insulin-responsive compartment. They are ordered first by their pain relevance and then by number of times they were reported in insulin-responsive compartment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16431 Localization of Lnpep 62 0.70 6.28 23.94
2 INT48131 Gene_expression of Slc2a4 32 0.78 14.64 10.16
3 INT10627 Positive_regulation of Lnpep 24 0.69 3.36 7.85
4 INT99430 Positive_regulation of Gene_expression of Slc2a4 18 0.66 10.45 7.79
5 INT10624 Regulation of Lnpep 13 0.61 3.27 5.6
6 INT16432 Positive_regulation of Localization of Lnpep 12 0.32 1.15 5.05
7 INT39786 Transcription of Lnpep 3 0.69 0.52 3.61
8 INT32340 Negative_regulation of Lnpep 14 0.49 2.63 3.26
9 INT17673 Negative_regulation of Localization of Lnpep 8 0.09 2.63 3.12
10 INT200670 Gene_expression of AKT2 25 0.75 16.25 3
11 INT12903 Gene_expression of Lnpep 14 0.71 1.3 2.78
12 INT115250 Positive_regulation of Slc2a4 16 0.67 8.13 2.64
13 INT48130 Transcription of Slc2a4 9 0.69 5.58 2.46
14 INT16433 Regulation of Localization of Lnpep 6 0.11 0.32 2.45
15 INT10626 Regulation of Positive_regulation of Lnpep 2 0.11 0.1 2.31
16 INT115256 Localization of Slc2a4 13 0.77 8.06 1.72
17 INT48126 Negative_regulation of Gene_expression of Slc2a4 5 0.59 1.79 1.63
18 INT48128 Regulation of Gene_expression of Slc2a4 5 0.62 1.25 1.59
19 INT230805 Localization of Slc2a4 23 0.46 11 1.48
20 INT48129 Negative_regulation of Slc2a4 7 0.59 3.19 1.21
21 INT160054 Localization of AKT2 4 0.73 1.93 1.18
22 INT39785 Positive_regulation of Transcription of Lnpep 2 0.50 0.47 1.18
23 INT55294 Gene_expression of Slc2a4 17 0.70 6.84 1.11
24 INT256006 Negative_regulation of Lnpep 1 0.48 2.61 0.9
25 INT160056 Positive_regulation of AKT2 3 0.48 1.43 0.88
26 INT141865 Positive_regulation of Transcription of Slc2a4 3 0.45 2.78 0.87
27 INT271605 Regulation of Gene_expression of AKT2 1 0.44 0.81 0.87
28 INT115249 Binding of Slc2a4 7 0.36 2.63 0.8
29 INT141115 Negative_regulation of Transcription of Lnpep 1 0.31 0 0.76
30 INT200669 Negative_regulation of AKT2 2 0.42 0.94 0.72
31 INT230808 Positive_regulation of Localization of Slc2a4 12 0.40 5.42 0.7
32 INT48133 Regulation of Slc2a4 2 0.45 0.23 0.6
33 INT30783 Positive_regulation of Gene_expression of Lnpep 3 0.64 0.66 0.53
34 INT142911 Binding of Lnpep 5 0.31 0.36 0.52
35 INT55293 Positive_regulation of Gene_expression of Slc2a4 7 0.63 4.18 0.51
36 INT141117 Regulation of Transcription of Lnpep 1 0.14 0 0.51
37 INT57943 Protein_catabolism of Lnpep 2 0.89 0.09 0.5
38 INT48132 Negative_regulation of Transcription of Slc2a4 1 0.43 0 0.48
39 INT271604 Positive_regulation of Gene_expression of AKT2 2 0.49 0.22 0.47
40 INT256014 Binding of Lnpep 1 0.31 0.64 0.39
41 INT126919 Regulation of Localization of Slc2a4 3 0.40 2.24 0.37
42 INT253118 Negative_regulation of Localization of Slc2a4 3 0.25 2.47 0.33
43 INT126920 Phosphorylation of Slc2a4 3 0.73 1.98 0.31
44 INT323118 Positive_regulation of Localization of AKT2 2 0.49 0.48 0.31
45 INT207096 Phosphorylation of Akt2 1 0.72 0.51 0.27
46 INT62808 Positive_regulation of SLC2A4 7 0.50 3.3 0.24
47 INT62810 Localization of SLC2A4 5 0.81 0.77 0.22
48 INT126921 Positive_regulation of Phosphorylation of Slc2a4 2 0.41 1.26 0.21
49 INT256005 Localization of Lnpep 1 0.66 0.97 0.21
50 INT229317 Gene_expression of SLC2A4 10 0.69 6.88 0.2
51 INT200676 Phosphorylation of AKT2 1 0.53 1.01 0.19
52 INT256009 Positive_regulation of Lnpep 1 0.41 0.15 0.19
53 INT231256 Regulation of Slc2a4 3 0.21 0.76 0.18
54 INT142910 Negative_regulation of Negative_regulation of Lnpep 1 0.15 0 0.18
55 INT207705 Positive_regulation of Rab4a 1 0.33 0.94 0.17
56 INT179260 Binding of AKT2 2 0.27 1.8 0.15
57 INT256007 Negative_regulation of Localization of Lnpep 1 0.35 0.88 0.15
58 INT277389 Positive_regulation of Gene_expression of SLC2A4 4 0.61 2.87 0.14
59 INT62809 Positive_regulation of Localization of SLC2A4 3 0.70 0.8 0.14
60 INT286401 Gene_expression of Akt2 8 0.72 1.36 0.13
61 INT71534 Negative_regulation of Positive_regulation of Lnpep 1 0.05 0.06 0.13
62 INT115251 Positive_regulation of Localization of Slc2a4 2 0.66 0.9 0.11
63 INT229102 Regulation of Phosphorylation of Slc2a4 1 0.00 0.53 0.11
64 INT236581 Regulation of Gene_expression of Slc2a4 3 0.36 0.5 0.09
65 INT352512 Regulation of Localization of Slc2a4 1 0.06 0.66 0.08
66 INT256011 Gene_expression of Lnpep 1 0.64 0.05 0.08
67 INT258085 Regulation of Localization of SLC2A4 1 0.22 0.75 0.06
68 INT238308 Negative_regulation of Localization of Slc2a4 1 0.12 0.25 0.05
69 INT207067 Localization of Akt2 2 0.69 0.59 0.04
70 INT286411 Binding of Akt2 1 0.34 0.23 0.04
71 INT200687 Positive_regulation of Phosphorylation of AKT2 1 0.33 0.43 0.04
72 INT253101 Binding of Slc2a4 1 0.21 0 0.03
73 INT286386 Positive_regulation of Akt2 2 0.61 0.45 0
74 INT246763 Gene_expression of Akt2 2 0.53 1.22 0
75 INT268154 Gene_expression of Rab4a 1 0.27 0.45 0
76 INT200678 Transcription of AKT2 1 0.47 0.57 0
77 INT296979 Regulation of Gene_expression of SLC2A4 1 0.19 0.56 0
78 INT296970 Positive_regulation of Transcription of SLC2A4 1 0.32 0.99 0
79 INT256012 Positive_regulation of Gene_expression of Lnpep 1 0.41 0.05 0
80 INT268312 Negative_regulation of Negative_regulation of Slc2a4 1 0.26 0.31 0
81 INT317361 Negative_regulation of Gene_expression of Slc2a4 1 0.40 0.15 0
82 INT277382 Negative_regulation of SLC2A4 1 0.38 0.48 0
83 INT286374 Positive_regulation of Transcription of Akt2 1 0.64 0 0
84 INT296971 Binding of SLC2A4 1 0.26 1.13 0
85 INT286375 Positive_regulation of Gene_expression of Akt2 1 0.43 0 0
86 INT200685 Negative_regulation of Gene_expression of AKT2 1 0.38 6.09 0
87 INT286404 Negative_regulation of Gene_expression of Akt2 1 0.39 0.06 0
88 INT286414 Transcription of Akt2 1 0.66 0 0
89 INT336105 Positive_regulation of Slc2a4 1 0.39 0.63 0
90 INT286376 Positive_regulation of Positive_regulation of Akt2 1 0.43 0.17 0
91 INT127442 Regulation of Gene_expression of Lnpep 1 0.07 0.17 0
92 INT246746 Positive_regulation of Gene_expression of Akt2 1 0.23 0.32 0
93 INT348217 Regulation of Akt2 1 0.13 0.25 0
94 INT200686 Negative_regulation of Transcription of AKT2 1 0.28 0.58 0
95 INT268302 Negative_regulation of Slc2a4 1 0.26 0.31 0
96 INT327031 Negative_regulation of Akt2 1 0.38 0.27 0
97 INT348213 Positive_regulation of Akt2 1 0.32 0.58 0
98 INT323119 Protein_catabolism of AKT2 1 0.96 0 0
99 INT296961 Positive_regulation of Binding of SLC2A4 1 0.35 1.14 0
100 INT348210 Negative_regulation of Binding of Slc2a4 1 0.25 0.5 0
101 INT42698 Regulation of Negative_regulation of Lnpep 1 0.22 0 0
102 INT296983 Transcription of SLC2A4 1 0.37 1.56 0
103 INT255722 Phosphorylation of Slc2a4 1 0.46 1.3 0
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