GO:0032611

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Name interleukin-1 beta production
Categary Process
Go Slim No
Go Link GO:0032611
Unique Molecular Interactions 554
Total Molecular Interactions 814
Total Single Events 5033
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-1 beta production. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-1 beta production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
2 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
3 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
4 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
5 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
6 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
7 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
8 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
9 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
10 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
11 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
12 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
13 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
14 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
15 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
16 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
17 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
18 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
19 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
20 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
21 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
22 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
23 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
24 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
25 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
26 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
27 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
28 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
29 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
30 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
31 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
32 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
33 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
34 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
35 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
36 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
37 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
38 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
39 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
40 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
41 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
42 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
43 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
44 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
45 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
46 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
47 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
48 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
49 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
50 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
51 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
52 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
53 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
54 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
55 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
56 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
57 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
58 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
59 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
60 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
61 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
62 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
63 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
64 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
65 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
66 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
67 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
68 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
69 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
70 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98
71 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
72 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
73 INT240123 MIR885 Negative_regulation of IL1B 1 0.01 1.57 0.96
74 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
75 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
76 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93
77 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
78 INT161655 Gsr Regulation of Gene_expression of Il1b 1 0.20 1.84 0.9
79 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
80 INT136349 Il1b Positive_regulation of Positive_regulation of Oprl1 1 0.22 0.27 0.88
81 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
82 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87
83 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84
84 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
85 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83
86 INT10275 Il1b Positive_regulation of Gene_expression of Penk 1 0.49 0.75 0.83
87 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
88 INT339293 Casp1 Regulation of Localization of Il1 1 0.07 1.87 0.83
89 INT84717 Il1b Regulation of Cpox 1 0.00 0.37 0.83
90 INT65011 IL1B Positive_regulation of PTGER2 4 0.08 0.92 0.82
91 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
92 INT83094 IL1B Positive_regulation of Positive_regulation of BDKRB1 1 0.45 0.2 0.81
93 INT339291 Casp1 Positive_regulation of Il1 2 0.12 1.63 0.8
94 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
95 INT161481 Slc7a12 Regulation of Gene_expression of Il1b 1 0.14 1.21 0.77
96 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76
97 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
98 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75
99 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
100 INT144299 Il1b Positive_regulation of Oprm1 1 0.42 0.4 0.74
101 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
102 INT150993 Sfpq Positive_regulation of Gene_expression of Il1b 1 0.04 0.7 0.72
103 INT74941 IL1B Positive_regulation of Gene_expression of PTGER2 1 0.08 0.48 0.72
104 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71
105 INT73822 TAC1 Positive_regulation of Localization of IL1B 1 0.04 0.56 0.71
106 INT73824 TFF2 Positive_regulation of Localization of IL1B 1 0.02 0.56 0.71
107 INT83838 Binding of CEACAM6 and Il1b 1 0.05 0 0.71
108 INT113500 IL1B Positive_regulation of Gene_expression of BHLHE23 1 0.18 0.1 0.71
109 INT95148 CEL Regulation of IL1B 1 0.24 0.88 0.7
110 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
111 INT250932 IL1B Regulation of Gene_expression of BDNF 1 0.06 0.24 0.69
112 INT346233 PREP Regulation of IL1B 1 0.05 1.44 0.69
113 INT172142 IL10 Positive_regulation of Protein_catabolism of IL1B 2 0.03 1.69 0.68
114 INT172132 IL4 Positive_regulation of Protein_catabolism of IL1B 2 0.02 1.69 0.68
115 INT66537 IL1B Positive_regulation of Gene_expression of Fos 1 0.02 0 0.68
116 INT70998 IL1B Regulation of Gene_expression of Icam1 1 0.44 0.95 0.67
117 INT150994 Sfpq Negative_regulation of Gene_expression of Il1b 1 0.03 0.69 0.66
118 INT88194 ZAK Positive_regulation of Gene_expression of IL1B 1 0.07 0.94 0.66
119 INT152111 IL1B Negative_regulation of Ltp 1 0.03 0.85 0.66
120 INT270763 IL1B Negative_regulation of IKBKB 1 0.04 1.13 0.66
121 INT116441 IL1B Positive_regulation of Gene_expression of CCL2 2 0.04 0.62 0.65
122 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65
123 INT97508 Negative_regulation of Il1b Positive_regulation of Crh 1 0.31 0.89 0.65
124 INT70161 Casp1 Regulation of Oprd1 1 0.03 0 0.65
125 INT70162 Casp1 Regulation of Penk 1 0.03 0 0.64
126 INT58229 Il1b Regulation of Gene_expression of Fam166a 1 0.01 0 0.64
127 INT172139 IL4 Negative_regulation of IL1B 1 0.02 0.85 0.63
128 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
129 INT71526 Regulation of Il1b Positive_regulation of Il6 1 0.17 0.14 0.62
130 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
131 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
132 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61
133 INT103214 Binding of Il1b and Pnoc 1 0.40 0.23 0.61
134 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61
135 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61
136 INT132731 Positive_regulation of Binding of Il1b and Il6 1 0.46 1.2 0.61
137 INT128814 Ephb1 Negative_regulation of Gene_expression of Il1b 1 0.02 0.37 0.61
138 INT66766 Casp1 Positive_regulation of Transcription of Pla2g10 1 0.06 0.19 0.6
139 INT66768 Il1b Positive_regulation of Transcription of Pla2g10 1 0.05 0.22 0.6
140 INT105848 Il1b Positive_regulation of Gene_expression of Cpox 1 0.12 0.41 0.59
141 INT81915 HSF1 Negative_regulation of IL1B 1 0.51 0.65 0.59
142 INT128604 Casp1 Positive_regulation of Gene_expression of Fos 1 0.10 0.55 0.59
143 INT81917 HSF1 Positive_regulation of IL1B 1 0.41 0.65 0.59
144 INT128810 Il1b Positive_regulation of Gene_expression of Nos2 1 0.04 0.31 0.59
145 INT96240 Il13 Negative_regulation of Il1b 1 0.17 0.6 0.59
146 INT96242 Il13 Negative_regulation of Gene_expression of Il1b 1 0.15 0.67 0.59
147 INT128603 Il1b Positive_regulation of Gene_expression of Fos 1 0.50 0.59 0.58
148 INT58342 Calca Negative_regulation of Localization of IL1B 1 0.00 0.6 0.58
149 INT54620 IL1B Positive_regulation of Crh 1 0.01 0.39 0.58
150 INT176471 TNF Positive_regulation of Gene_expression of IL1B 1 0.02 0.61 0.57
151 INT108387 IL1B Positive_regulation of Localization of MMP1 1 0.27 0.3 0.57
152 INT143938 Il1rn Negative_regulation of Il1b 1 0.04 0.52 0.57
153 INT60665 Il1b Regulation of Oprd1 1 0.05 0 0.57
154 INT58805 Il1b Negative_regulation of LH 1 0.24 0 0.56
155 INT146112 Binding of Il1b and Tnf 1 0.32 1.19 0.56
156 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
157 INT339290 Casp1 Regulation of Gene_expression of Il1 1 0.11 1.38 0.55
158 INT297311 Casp1 Positive_regulation of Il18 1 0.09 1.02 0.55
159 INT80752 Binding of Il1b and El4 1 0.49 0.08 0.54
160 INT134488 Il1b Regulation of Oxt 1 0.30 0.08 0.54
161 INT80751 Negative_regulation of Binding of Il1b and El4 1 0.60 0.08 0.54
162 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
163 INT59601 Il1b Regulation of Localization of LH 1 0.18 0 0.54
164 INT66769 Negative_regulation of Il1b Positive_regulation of Pla2g10 1 0.04 0.25 0.53
165 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51
166 INT105849 Il1b Positive_regulation of Positive_regulation of Ptgs1 1 0.07 0.38 0.51
167 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51
168 INT254357 Binding of IFNA1 and IL1B 1 0.00 1.88 0.51
169 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51
170 INT58804 Il1b Negative_regulation of Negative_regulation of LH 1 0.24 0 0.51
171 INT250933 IL1B Positive_regulation of Gene_expression of BDNF 1 0.10 0.27 0.5
172 INT64720 Regulation of IL1B Positive_regulation of IL6 1 0.36 0.65 0.5
173 INT169400 Negative_regulation of IRF6 Positive_regulation of Gene_expression of Il1b 1 0.50 0.62 0.5
174 INT20546 IL1B Regulation of Gene_expression of SGCG 1 0.65 0.14 0.5
175 INT106074 IL1B Positive_regulation of Gene_expression of A2M 1 0.03 0.75 0.49
176 INT225025 IL1B Positive_regulation of Positive_regulation of Cxcl1 1 0.04 0.32 0.49
177 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
178 INT143939 Il1b Regulation of Gene_expression of Fos 1 0.10 0.44 0.49
179 INT10277 Il1b Positive_regulation of Transcription of Penk 1 0.46 0.26 0.49
180 INT94262 IL1B Positive_regulation of Localization of PTGER2 1 0.22 0.8 0.49
181 INT155621 Tnf Regulation of Transcription of Il1b 1 0.51 0.77 0.49
182 INT289462 Negative_regulation of IRF6 Positive_regulation of IL1B 2 0.04 0.31 0.48
183 INT114593 Il1b Positive_regulation of Gene_expression of Ppt1 1 0.05 0.06 0.48
184 INT85736 Positive_regulation of Il1b Positive_regulation of Tpgs2 1 0.02 0.2 0.48
185 INT300960 Il4 Negative_regulation of IL1B 1 0.03 0.37 0.48
186 INT289463 IRF6 Positive_regulation of Localization of IL1B 1 0.05 0.52 0.48
187 INT114595 Il1b Positive_regulation of Gene_expression of Rent1 1 0.00 0.06 0.48
188 INT130726 Negative_regulation of Binding of IL1B and Il1rn 1 0.01 0.6 0.48
189 INT62164 Il1b Positive_regulation of PTGS2 1 0.00 0.49 0.47
190 INT62163 Il1b Positive_regulation of Positive_regulation of PTGS2 1 0.00 0.49 0.47
191 INT148818 IL1B Regulation of Gene_expression of TNC 1 0.29 0.57 0.47
192 INT85735 Il1b Positive_regulation of Tpgs2 1 0.02 0.2 0.47
193 INT106073 IL1B Positive_regulation of Positive_regulation of NFKB1 1 0.41 0.7 0.47
194 INT138154 IL1B Positive_regulation of Transcription of Mmp2 1 0.04 0.23 0.46
195 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46
196 INT138160 IL1B Positive_regulation of Gene_expression of Mmp3 1 0.03 0.23 0.46
197 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46
198 INT57983 Il1b Regulation of Crh 1 0.37 0.09 0.44
199 INT197113 RETNLB Regulation of IL1B 1 0.00 1.27 0.44
200 INT57981 Regulation of Il1b Positive_regulation of Crh 1 0.22 0.1 0.44

Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-1 beta production. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-1 beta production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
2 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
3 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
4 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
5 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
6 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
7 INT6849 Localization of IL1B 229 0.81 112.56 69.63
8 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
9 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
10 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
11 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
12 INT6484 Binding of IL1B 122 0.47 75.84 35.07
13 INT9347 Localization of Il1b 58 0.81 26.13 31.53
14 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
15 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
16 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
17 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
18 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
19 INT48081 Localization of Il1b 46 0.80 21.59 22.4
20 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
21 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
22 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
23 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
24 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
25 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
26 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
27 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67
28 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
29 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
30 INT70848 Gene_expression of Casp1 24 0.77 10.97 8.52
31 INT66926 Transcription of Il1b 15 0.69 13.16 7.81
32 INT48077 Positive_regulation of Localization of Il1b 17 0.69 8.8 7.68
33 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
34 INT69033 Negative_regulation of Casp1 21 0.58 13.15 7.52
35 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
36 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
37 INT48076 Negative_regulation of Localization of Il1b 10 0.59 3.46 6.58
38 INT81586 Negative_regulation of Casp1 11 0.57 6.55 6.45
39 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
40 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
41 INT84716 Negative_regulation of Positive_regulation of Il1b 9 0.57 5.34 6.27
42 INT90077 Gene_expression of Casp1 29 0.76 20.79 6.26
43 INT80750 Binding of Il1b 11 0.47 7.97 5.95
44 INT71220 Positive_regulation of Casp1 15 0.38 10.23 5.84
45 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
46 INT10705 Binding of Il1b 9 0.36 2.8 5.53
47 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
48 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
49 INT48080 Positive_regulation of Positive_regulation of Il1b 5 0.50 4.3 4.19
50 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12
51 INT66922 Positive_regulation of Transcription of Il1b 7 0.49 6.58 3.14
52 INT6479 Negative_regulation of Binding of IL1B 10 0.43 5.1 2.78
53 INT112147 Positive_regulation of Negative_regulation of Il1b 3 0.49 3.42 2.77
54 INT10350 Negative_regulation of Regulation of Il1b 3 0.41 0.58 2.69
55 INT11379 Positive_regulation of Negative_regulation of IL1B 9 0.49 7.2 2.64
56 INT107433 Localization of Casp1 6 0.56 2.44 2.64
57 INT15144 Protein_catabolism of IL1B 11 0.92 4.67 2.58
58 INT156876 Positive_regulation of Gene_expression of Casp1 10 0.50 10.25 2.58
59 INT205692 Positive_regulation of Positive_regulation of Casp1 5 0.46 3 2.44
60 INT36055 Positive_regulation of Transcription of IL1B 9 0.49 6.24 2.21
61 INT73906 Regulation of Transcription of IL1B 5 0.56 3.46 2.1
62 INT55035 Negative_regulation of Negative_regulation of Il1b 4 0.43 1.46 2.02
63 INT168275 Phosphorylation of Il1b 1 0.79 2.39 2.01
64 INT171323 Phosphorylation of IL1B 5 0.57 4.13 1.94
65 INT116033 Negative_regulation of Transcription of Il1b 4 0.42 2.05 1.94
66 INT14246 Regulation of Positive_regulation of IL1B 7 0.44 3.04 1.77
67 INT116498 Negative_regulation of Negative_regulation of IL1B 7 0.41 3.08 1.7
68 INT73901 Negative_regulation of Transcription of IL1B 3 0.53 0.46 1.57
69 INT69034 Regulation of Casp1 3 0.27 3.56 1.36
70 INT96073 Localization of Casp1 11 0.78 4.91 1.29
71 INT73590 Positive_regulation of Positive_regulation of Casp1 2 0.19 1.94 1.28
72 INT94744 Regulation of Transcription of Il1b 3 0.44 2.83 1.26
73 INT173114 Positive_regulation of Binding of IL1B 6 0.49 2.56 1.22
74 INT209912 Gene_expression of Pycard 17 0.22 12.04 1.04
75 INT9348 Regulation of Localization of Il1b 2 0.27 0.14 1.04
76 INT267750 Binding of Casp1 4 0.35 1.53 1.02
77 INT25264 Regulation of Negative_regulation of IL1B 3 0.27 1.17 1.02
78 INT50989 Regulation of Positive_regulation of Il1b 2 0.42 0.86 1.02
79 INT346201 Negative_regulation of Phosphorylation of IL1B 1 0.20 1.69 1.01
80 INT168280 Positive_regulation of Phosphorylation of Il1b 1 0.49 1.1 0.93
81 INT115238 Positive_regulation of Gene_expression of Casp1 5 0.68 1.78 0.88
82 INT96074 Negative_regulation of Gene_expression of Casp1 4 0.57 2.77 0.87
83 INT205685 Regulation of Positive_regulation of Casp1 3 0.11 1.62 0.78
84 INT182049 Protein_catabolism of Casp1 3 0.20 1.64 0.73
85 INT163783 Transcription of Casp1 1 0.58 0.88 0.73
86 INT163785 Positive_regulation of Transcription of Casp1 1 0.42 0.89 0.73
87 INT127822 Negative_regulation of Transcription of Il1b 2 0.42 1.2 0.72
88 INT70156 Regulation of Casp1 2 0.15 0.79 0.7
89 INT138237 Negative_regulation of Negative_regulation of Casp1 1 0.30 0.56 0.69
90 INT138235 Positive_regulation of Pycard 2 0.33 1.66 0.62
91 INT71172 Negative_regulation of Gene_expression of Casp1 2 0.58 1.3 0.58
92 INT83618 Regulation of Positive_regulation of Il1b 2 0.44 1.04 0.58
93 INT81352 Negative_regulation of Regulation of IL1B 2 0.41 0.51 0.58
94 INT138239 Localization of Pycard 2 0.53 1.05 0.58
95 INT138238 Positive_regulation of Localization of Pycard 1 0.33 0.66 0.58
96 INT138236 Positive_regulation of Localization of Casp1 2 0.48 0.82 0.54
97 INT90078 Negative_regulation of Positive_regulation of Casp1 2 0.42 1.38 0.53
98 INT254317 Negative_regulation of Pycard 5 0.42 3.13 0.45
99 INT107432 Negative_regulation of Localization of Casp1 1 0.03 0 0.42
100 INT117939 Transcription of Casp1 1 0.27 0.89 0.4
101 INT117938 Negative_regulation of Transcription of Casp1 1 0.22 0.89 0.4
102 INT91975 Regulation of Binding of IL1B 2 0.14 0.66 0.38
103 INT153878 Negative_regulation of Negative_regulation of Il1b 1 0.42 0.78 0.36
104 INT209911 Protein_catabolism of Pycard 2 0.11 1.58 0.33
105 INT209937 Negative_regulation of Protein_catabolism of IL1B 2 0.24 1.15 0.32
106 INT273978 Gene_expression of Pycard 2 0.10 1.96 0.29
107 INT298971 Positive_regulation of Localization of Casp1 2 0.06 0.97 0.28
108 INT317821 Regulation of Gene_expression of Casp1 1 0.05 1.74 0.24
109 INT216978 Binding of Pycard 6 0.25 2.93 0.22
110 INT155532 Regulation of Regulation of IL1B 2 0.26 0.32 0.22
111 INT281991 Regulation of Negative_regulation of Il1b 1 0.03 0.77 0.2
112 INT117736 Regulation of Localization of Il1b 1 0.02 1.33 0.18
113 INT262796 Positive_regulation of Pycard 12 0.22 6.5 0.14
114 INT97512 Binding of Pycard 1 0.01 0.78 0.14
115 INT134981 Positive_regulation of Regulation of IL1B 2 0.49 0.69 0.1
116 INT267759 Negative_regulation of Binding of Casp1 1 0.04 0.09 0.1
117 INT326432 Regulation of Positive_regulation of Pycard 1 0.07 0.31 0.04
118 INT262801 Regulation of Gene_expression of Pycard 1 0.08 1.8 0.04
119 INT349816 Regulation of Pycard 1 0.26 0.56 0.04
120 INT192301 Positive_regulation of Protein_catabolism of IL1B 1 0.18 0.15 0.03
121 INT262795 Localization of Pycard 2 0.26 1.61 0
122 INT262800 Positive_regulation of Binding of Pycard 1 0.09 0.75 0
123 INT16046 Regulation of Regulation of Il1b 1 0.45 0 0
124 INT353117 Negative_regulation of Positive_regulation of Casp1 1 0.06 1.25 0
125 INT270800 Positive_regulation of Gene_expression of Pycard 1 0.04 0.2 0
126 INT326434 Regulation of Pycard 1 0.07 0.38 0
127 INT278333 Phosphorylation of Pycard 1 0.11 0 0
128 INT326433 Protein_catabolism of Pycard 1 0.10 0 0
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