GO:0032651

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Name regulation of interleukin-1 beta production
Categary Process
Go Slim No
Go Link GO:0032651
Unique Molecular Interactions 67
Total Molecular Interactions 105
Total Single Events 546
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of interleukin-1 beta production. They are ordered first by their pain relevance and then by number of times they were reported for regulation of interleukin-1 beta production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
2 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
3 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
4 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
5 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92
6 INT338057 Positive_regulation of F2r Positive_regulation of Localization of Calca 1 0.05 0.28 0.71
7 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
8 INT167907 Binding of F2r and ITS 1 0.01 0.7 0.55
9 INT338038 Gopc Regulation of Gene_expression of F2r 1 0.08 0 0.52
10 INT338045 F2r Regulation of Localization of Calca 1 0.03 0.05 0.52
11 INT353331 Elane Positive_regulation of F2r 1 0.08 0.78 0.44
12 INT338059 Nrtn Positive_regulation of Gene_expression of F2r 1 0.12 0.45 0.41
13 INT156237 Binding of F2r and Tnfsf14 1 0.02 1.14 0.4
14 INT353332 Binding of F2r and Pawr 1 0.18 0.67 0.39
15 INT156235 Tnfsf14 Positive_regulation of F2r 1 0.03 1.03 0.35
16 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32
17 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32
18 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31
19 INT191799 PROC Negative_regulation of Binding of F2r 1 0.00 0.92 0.3
20 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28
21 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26
22 INT123663 F2R Positive_regulation of MAPK14 1 0.12 0.42 0.26
23 INT123662 Negative_regulation of F2R Positive_regulation of MAPK14 1 0.08 0.42 0.26
24 INT305686 Binding of Gfap and F2r 1 0.01 0 0.25
25 INT158621 Binding of SIGMAR1 and Sphk1 1 0.01 0 0.25
26 INT191792 Binding of F2r and Serpinc1 1 0.00 3.74 0.24
27 INT123660 F2R Positive_regulation of PAR1 2 0.10 1.96 0.22
28 INT338042 F2r Positive_regulation of Localization of Prkca 1 0.06 0.1 0.2
29 INT123664 F2R Positive_regulation of PAR4 1 0.03 0.51 0.19
30 INT195115 Gene_expression of Gopc Positive_regulation of Positive_regulation of F2r 1 0.17 1.67 0.18
31 INT195114 Gene_expression of Il1r1 Positive_regulation of Positive_regulation of F2r 1 0.38 1.67 0.18
32 INT207144 F2r Positive_regulation of Pawr 1 0.14 0.51 0.16
33 INT207117 Binding of VEGFA and F2r 1 0.02 0.56 0.15
34 INT338040 Ctsg Positive_regulation of F2r 1 0.29 0 0.15
35 INT338052 F2r Positive_regulation of F2rl3 1 0.12 0 0.15
36 INT338041 F2r Positive_regulation of Pard3 1 0.15 0.05 0.11
37 INT262255 Binding of APC and F2R 1 0.05 3 0.1
38 INT353341 F2r Positive_regulation of Negative_regulation of Mif 1 0.49 0 0.05
39 INT261728 PSMB6 Negative_regulation of Transcription of F2R 1 0.01 0.17 0.03
40 INT175628 F2R Positive_regulation of F2RL1 1 0.04 1.46 0.03
41 INT261729 COL5A2 Regulation of Gene_expression of F2R 1 0.18 0 0
42 INT287676 Negative_regulation of Sphk1 Negative_regulation of Pik3r1 1 0.14 0.42 0
43 INT287673 Negative_regulation of Sphk1 Negative_regulation of Akt1 1 0.20 0.42 0
44 INT261732 F2 Positive_regulation of F2R 1 0.14 0 0
45 INT338047 Binding of F2r and Pard3 1 0.11 0 0
46 INT142143 F2r Regulation of Plcg1 1 0.02 0.07 0
47 INT213015 Binding of S1pr1 and S1pr3 1 0.16 1.17 0
48 INT261730 ROCK1 Positive_regulation of Positive_regulation of F2R 1 0.37 0 0
49 INT142142 F2r Positive_regulation of Phosphorylation of Plcg1 1 0.03 0.08 0
50 INT353337 F2r Positive_regulation of Gene_expression of Mif 1 0.46 0 0
51 INT261735 Positive_regulation of F2 Positive_regulation of F2R 1 0.14 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of interleukin-1 beta production. They are ordered first by their pain relevance and then by number of times they were reported in regulation of interleukin-1 beta production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118512 Gene_expression of F2r 33 0.63 26.56 18.26
2 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36
3 INT117497 Positive_regulation of F2r 18 0.57 14.45 8.13
4 INT90852 Gene_expression of F2r 26 0.78 5.5 4.66
5 INT46754 Localization of F2r 7 0.78 2.36 3.24
6 INT58433 Negative_regulation of F2r 9 0.59 2.77 3.08
7 INT82653 Regulation of F2r 8 0.36 3.78 2.62
8 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61
9 INT150339 Gene_expression of F2R 10 0.73 3.59 2.46
10 INT82652 Negative_regulation of F2r 4 0.37 3.5 2.19
11 INT138439 Positive_regulation of Gene_expression of Sphk1 14 0.48 5.93 1.86
12 INT154816 Negative_regulation of Sphk1 19 0.41 11.38 1.84
13 INT156231 Binding of F2r 9 0.23 3.78 1.57
14 INT117498 Regulation of Positive_regulation of F2r 1 0.18 0.91 1.24
15 INT98976 Regulation of F2r 7 0.60 0.71 1.22
16 INT338033 Localization of F2r 1 0.41 0.62 1.2
17 INT138434 Positive_regulation of Sphk1 10 0.48 2.18 1.18
18 INT195105 Negative_regulation of Gene_expression of F2r 3 0.37 1.41 0.91
19 INT24372 Negative_regulation of Sphk1 1 0.59 0 0.85
20 INT195099 Positive_regulation of Gene_expression of F2r 7 0.57 5.31 0.78
21 INT353325 Positive_regulation of Localization of F2r 1 0.49 1.31 0.76
22 INT62192 Regulation of Localization of F2r 2 0.60 0.59 0.7
23 INT24373 Gene_expression of Sphk1 3 0.67 0 0.68
24 INT207089 Regulation of Negative_regulation of F2r 1 0.17 1.49 0.62
25 INT353321 Regulation of Positive_regulation of F2r 1 0.60 0.6 0.62
26 INT123672 Positive_regulation of F2R 9 0.47 0.77 0.58
27 INT142983 Positive_regulation of S1pr3 2 0.57 1.66 0.57
28 INT191777 Binding of F2r 2 0.02 0.89 0.54
29 INT338026 Regulation of Localization of F2r 1 0.25 0.05 0.52
30 INT24375 Regulation of Sphk1 1 0.62 0 0.5
31 INT24371 Positive_regulation of Sphk1 2 0.41 2.37 0.46
32 INT144981 Binding of F2R 3 0.36 1.66 0.35
33 INT353324 Negative_regulation of Positive_regulation of F2r 1 0.41 0.24 0.35
34 INT24374 Regulation of Gene_expression of Sphk1 1 0.45 0 0.31
35 INT62191 Negative_regulation of Localization of F2r 1 0.35 0 0.26
36 INT195091 Negative_regulation of Positive_regulation of F2r 1 0.48 1.69 0.25
37 INT302791 Negative_regulation of Gene_expression of Sphk1 1 0.23 0.34 0.24
38 INT305682 Positive_regulation of Positive_regulation of F2r 1 0.03 0 0.24
39 INT195112 Positive_regulation of Positive_regulation of F2r 1 0.41 0.97 0.18
40 INT261745 Regulation of F2R 1 0.43 0.22 0.16
41 INT261739 Regulation of Gene_expression of F2R 1 0.26 0.22 0.16
42 INT98700 Regulation of Gene_expression of F2r 1 0.45 0 0.15
43 INT287672 Positive_regulation of Positive_regulation of Sphk1 1 0.48 0.38 0.14
44 INT207087 Negative_regulation of Binding of F2r 1 0.27 0.06 0.14
45 INT158618 Binding of Sphk1 1 0.01 0 0.13
46 INT287665 Regulation of Negative_regulation of Sphk1 1 0.43 0.11 0.1
47 INT307530 Negative_regulation of Binding of F2R 1 0.03 0 0.09
48 INT145503 Protein_catabolism of F2r 1 0.66 0.46 0.07
49 INT195082 Regulation of Gene_expression of F2r 1 0.37 0.67 0.07
50 INT261737 Transcription of F2R 1 0.50 0.31 0.05
51 INT345101 Gene_expression of S1pr3 1 0.31 0.05 0.03
52 INT353327 Transcription of F2r 1 0.67 0.21 0.03
53 INT191771 Positive_regulation of Gene_expression of F2r 1 0.01 0.31 0.03
54 INT338031 Transcription of F2r 1 0.39 0 0
55 INT287663 Localization of Sphk1 1 0.72 0.84 0
56 INT287668 Regulation of Sphk1 1 0.43 0.66 0
57 INT287664 Binding of Sphk1 1 0.36 0.97 0
58 INT353323 Negative_regulation of Gene_expression of F2r 1 0.41 0 0
59 INT261741 Negative_regulation of Positive_regulation of F2R 1 0.40 0 0
60 INT261743 Positive_regulation of Positive_regulation of F2R 1 0.44 0 0
61 INT287661 Regulation of Positive_regulation of Sphk1 1 0.43 0 0
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