GO:0032700

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Name negative regulation of interleukin-17 production
Categary Process
Go Slim No
Go Link GO:0032700
Unique Molecular Interactions 974
Total Molecular Interactions 1412
Total Single Events 9133
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of interleukin-17 production. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of interleukin-17 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
5 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
6 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26
7 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
8 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
9 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
10 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
11 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
12 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
13 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
14 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
15 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
16 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
17 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52
18 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
19 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
20 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
21 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
22 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
23 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
24 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
25 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26
26 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
27 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
28 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
29 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
30 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
31 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 0.04 1.42 1.21
32 INT70044 IL12A Regulation of PRF1 1 0.04 1.42 1.21
33 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
34 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
35 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
36 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
37 INT156545 Il13 Positive_regulation of Gene_expression of Il12a 1 0.27 1.56 1.13
38 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
39 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
40 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
41 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
42 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
43 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
44 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
45 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
46 INT128700 BBS9 Negative_regulation of Il12a 1 0.47 0.76 1.03
47 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
48 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
49 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99
50 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
51 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
52 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
53 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
54 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
55 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
56 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92
57 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
58 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
59 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
60 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89
61 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
62 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
63 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
64 INT133176 Regulation of Mastl Negative_regulation of Il12a 1 0.01 0.24 0.86
65 INT133177 Mastl Negative_regulation of Il12a 1 0.01 0.24 0.86
66 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
67 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
68 INT249656 tm Positive_regulation of Il12a 1 0.07 1.17 0.84
69 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
70 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
71 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
72 INT113240 Il12a Regulation of Transcription of Tacr1 1 0.21 0.79 0.82
73 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79
74 INT113238 Il12a Positive_regulation of Transcription of Tacr1 1 0.38 0.78 0.79
75 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
76 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
77 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
78 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
79 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
80 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
81 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72
82 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
83 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72
84 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
85 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72
86 INT146460 IFNG Positive_regulation of Gene_expression of TNFRSF10D 1 0.03 1.46 0.72
87 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
88 INT151679 Ifng Negative_regulation of Oas1b 1 0.12 1.24 0.71
89 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
90 INT151676 Ifng Negative_regulation of Art2a-ps 1 0.00 1.25 0.71
91 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
92 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7
93 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
94 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
95 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
96 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
97 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
98 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
99 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
100 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
101 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64
102 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64
103 INT56235 Ifng Positive_regulation of Gene_expression of RT1-EC2 1 0.23 0.33 0.62
104 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
105 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61
106 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
107 INT176365 IL12A Positive_regulation of Gene_expression of IFNA1 1 0.13 1.35 0.6
108 INT154533 Ifng Negative_regulation of Il4 1 0.11 0.62 0.6
109 INT154531 Ifng Negative_regulation of Il10 1 0.30 0.61 0.6
110 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
111 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
112 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
113 INT250326 Binding of Il12a and Rpsa 1 0.09 0.93 0.59
114 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
115 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59
116 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58
117 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
118 INT283980 Binding of IL12A and IL23A 2 0.24 1.33 0.57
119 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
120 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
121 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57
122 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57
123 INT110032 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il12a 1 0.36 0 0.57
124 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
125 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
126 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
127 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
128 INT176371 LBR Positive_regulation of IL12A 1 0.04 1.22 0.55
129 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
130 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
131 INT137162 IFNG Positive_regulation of Gene_expression of CXCL9 1 0.45 0.62 0.54
132 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54
133 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54
134 INT88024 Ifng Positive_regulation of Gene_expression of Faslg 2 0.50 1.19 0.53
135 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
136 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52
137 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
138 INT138928 Ifng Positive_regulation of Transcription of Cxcl9 1 0.31 0.65 0.51
139 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51
140 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51
141 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51
142 INT143504 IFNG Positive_regulation of Gene_expression of Aif1 1 0.04 1.26 0.51
143 INT70925 Binding of Ifng and Il4 2 0.14 0.9 0.5
144 INT217037 Binding of IRF6 and Il12a 1 0.01 0.08 0.5
145 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
146 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49
147 INT240537 Binding of Il12a and Ebi3 1 0.08 1.23 0.49
148 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49
149 INT138927 Ifng Positive_regulation of Gene_expression of Stat1 1 0.29 0.7 0.49
150 INT142155 Ifng Positive_regulation of Il5 1 0.08 0 0.48
151 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
152 INT184117 Il12a Positive_regulation of Stat6 1 0.07 0.28 0.48
153 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48
154 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47
155 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
156 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
157 INT284300 Tlr4 Positive_regulation of Gene_expression of Mir155 1 0.18 0.91 0.47
158 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47
159 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
160 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46
161 INT99790 Ifng Positive_regulation of Cxcr2 1 0.12 0.28 0.46
162 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46
163 INT176364 IL12A Regulation of Positive_regulation of IFNA1 1 0.12 0.59 0.46
164 INT310769 Pam Regulation of Tlr4 1 0.01 0.69 0.46
165 INT95564 Positive_regulation of HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
166 INT95562 HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
167 INT222924 Negative_regulation of Pde4a Negative_regulation of Gene_expression of Il12a 1 0.01 0.59 0.45
168 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44
169 INT209049 Slc11a1 Positive_regulation of Localization of Il12a 1 0.04 0.09 0.44
170 INT126337 Pax3 Positive_regulation of Gene_expression of Ifng 1 0.05 0.56 0.44
171 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44
172 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
173 INT126340 Pax3 Regulation of Gene_expression of Ifng 1 0.03 0.56 0.44
174 INT126338 Insrr Regulation of Gene_expression of Ifng 1 0.00 0.56 0.43
175 INT189154 MTNR1B Positive_regulation of Gene_expression of IFNG 1 0.01 0.06 0.43
176 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
177 INT210225 Ptpn2 Positive_regulation of Gene_expression of Ifng 1 0.15 1.44 0.42
178 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
179 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42
180 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41
181 INT17305 Ifng Positive_regulation of RT1-CE1 1 0.06 0.46 0.41
182 INT231303 Binding of Prnp and Helt 1 0.02 3.23 0.41
183 INT17308 Ifng Positive_regulation of Atp8a1 1 0.64 0.45 0.41
184 INT231304 Prnp Negative_regulation of Grin2d 2 0.38 0.5 0.4
185 INT100598 PRNP Positive_regulation of Gene_expression of IL6 1 0.40 0.23 0.4
186 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
187 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
188 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
189 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39
190 INT292887 IL4 Regulation of IL12A 1 0.01 0.25 0.39
191 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
192 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
193 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
194 INT237778 Il12b Positive_regulation of Gene_expression of Eae1 1 0.01 1.51 0.39
195 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
196 INT292889 IL2 Regulation of IL12A 1 0.01 0.25 0.39
197 INT141016 Il18 Positive_regulation of Gene_expression of Ifng 1 0.39 0.27 0.39
198 INT292888 TNF Regulation of IL12A 1 0.02 0.25 0.39
199 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38
200 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of interleukin-17 production. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of interleukin-17 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
2 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
3 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
4 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
5 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
6 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
7 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
8 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97
9 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
10 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
11 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
12 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
13 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
14 INT8518 Localization of Ifng 53 0.81 36.68 24.13
15 INT134651 Binding of TLR4 89 0.48 66.96 23.19
16 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
17 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5
18 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
19 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
20 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
21 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85
22 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98
23 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
24 INT19509 Localization of Ifng 55 0.78 28.25 18.67
25 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
26 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
27 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
28 INT93948 Negative_regulation of Gene_expression of Il12a 48 0.55 27.77 16.87
29 INT103757 Negative_regulation of Il12a 37 0.55 21.62 16.38
30 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
31 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
32 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
33 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
34 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
35 INT4931 Localization of IFNG 53 0.78 33.25 13.65
36 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
37 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34
38 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
39 INT61624 Positive_regulation of Gene_expression of IL12A 50 0.56 33.07 13.07
40 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
41 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
42 INT87239 Localization of Il12a 51 0.75 31.95 12.05
43 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
44 INT67401 Gene_expression of Il12a 25 0.55 20.04 11.12
45 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
46 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
47 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68
48 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16
49 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25
50 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
51 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
52 INT91667 Localization of IL12A 39 0.74 25.51 7.36
53 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
54 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
55 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11
56 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
57 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67
58 INT77945 Regulation of Gene_expression of Il12a 19 0.58 6.55 6.4
59 INT74154 Transcription of Ifng 14 0.67 10.33 6.21
60 INT97797 Localization of TLR4 18 0.77 13.78 6
61 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
62 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
63 INT5186 Regulation of Ifng 11 0.45 8.78 5.9
64 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
65 INT83119 Negative_regulation of Gene_expression of IL12A 24 0.42 17.52 5.69
66 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
67 INT69572 Localization of Prnp 96 0.81 38.11 5.45
68 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43
69 INT106189 Regulation of Il12a 18 0.44 12.4 5.3
70 INT174688 Binding of Tlr2 45 0.42 36.65 5.25
71 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
72 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18
73 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
74 INT102254 Positive_regulation of Gene_expression of Prnp 72 0.70 38.11 4.81
75 INT62132 Regulation of Gene_expression of Ifng 12 0.62 1.28 4.77
76 INT98251 Binding of IL12A 20 0.37 16.03 4.51
77 INT69570 Binding of Prnp 75 0.48 44.26 4.37
78 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89
79 INT71374 Positive_regulation of Gene_expression of Il12a 5 0.22 7.49 3.8
80 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
81 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
82 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65
83 INT133169 Positive_regulation of Il12b 25 0.49 13 3.64
84 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
85 INT174160 Binding of Il12a 19 0.24 12.61 3.4
86 INT70051 Transcription of IL12A 7 0.25 5.61 3.39
87 INT87027 Positive_regulation of Localization of IFNG 12 0.67 5.78 3.35
88 INT102255 Regulation of Prnp 35 0.62 18.97 3.25
89 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
90 INT79553 Localization of Il12a 9 0.31 5.85 3.16
91 INT78467 Negative_regulation of IL12A 18 0.38 11.29 2.98
92 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
93 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
94 INT133174 Positive_regulation of Gene_expression of Il12b 29 0.15 13.04 2.92
95 INT114181 Negative_regulation of Positive_regulation of Il12a 7 0.34 3.65 2.82
96 INT67078 Binding of Ifng 7 0.48 4.84 2.73
97 INT15197 Regulation of Gene_expression of Ifng 8 0.34 2.66 2.69
98 INT102253 Negative_regulation of Prnp 75 0.59 24.23 2.62
99 INT111145 Negative_regulation of Positive_regulation of Ifng 7 0.41 2.21 2.61
100 INT91669 Negative_regulation of Localization of IFNG 5 0.57 4.1 2.58
101 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
102 INT135040 Regulation of Gene_expression of Prnp 30 0.62 10.52 2.45
103 INT16964 Binding of IFNG 27 0.48 14.31 2.45
104 INT73980 Transcription of Ifng 12 0.72 5.42 2.4
105 INT70918 Positive_regulation of Localization of Ifng 5 0.45 2.79 2.33
106 INT67437 Negative_regulation of Localization of Ifng 7 0.47 2.23 2.28
107 INT85878 Negative_regulation of Il12a 4 0.58 2.88 2.21
108 INT92648 Positive_regulation of IL12B 7 0.20 4.55 2.19
109 INT204775 Regulation of Tlr2 21 0.41 13.6 2.18
110 INT112784 Positive_regulation of Positive_regulation of IFNG 11 0.49 7.84 2.18
111 INT105378 Regulation of IL12A 6 0.26 8.82 2.15
112 INT85877 Positive_regulation of Il12a 6 0.43 4.87 2.11
113 INT140818 Positive_regulation of Positive_regulation of Ifng 2 0.47 4.2 2.06
114 INT74156 Positive_regulation of Il12b 3 0.49 1.54 2.04
115 INT111530 Positive_regulation of Regulation of Ifng 1 0.41 0.32 2.01
116 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
117 INT91663 Positive_regulation of Localization of IL12A 9 0.27 5.91 1.95
118 INT92056 Transcription of Il12b 8 0.69 4.75 1.95
119 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
120 INT11136 Positive_regulation of Localization of Ifng 4 0.49 3.13 1.89
121 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
122 INT258781 Regulation of Regulation of Il12a 1 0.17 1.54 1.87
123 INT133170 Negative_regulation of Il12b 12 0.05 5.32 1.86
124 INT140906 Negative_regulation of Gene_expression of Il12a 4 0.38 5.28 1.86
125 INT167203 Binding of PRNP 25 0.48 20.09 1.84
126 INT61627 Transcription of IFNG 6 0.69 4.28 1.83
127 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
128 INT91659 Negative_regulation of Localization of IL12A 8 0.14 3.9 1.75
129 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74
130 INT228195 Negative_regulation of Gene_expression of Tlr2 14 0.40 12.17 1.74
131 INT110950 Positive_regulation of Negative_regulation of Il12a 2 0.44 1.75 1.73
132 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
133 INT113716 Positive_regulation of Transcription of Ifng 1 0.53 2.56 1.61
134 INT128699 Regulation of Il12a 3 0.45 3.36 1.59
135 INT87241 Positive_regulation of Localization of Il12a 8 0.50 1.3 1.58
136 INT22785 Negative_regulation of PRNP 12 0.57 5.09 1.57
137 INT174230 Positive_regulation of Gene_expression of IL12B 6 0.49 3.2 1.56
138 INT110028 Transcription of Il12a 6 0.49 1.48 1.51
139 INT67398 Transcription of Il12a 3 0.26 3.16 1.49
140 INT97142 Localization of IL12B 5 0.73 1.73 1.46
141 INT95566 Positive_regulation of Positive_regulation of IL12A 10 0.41 7.47 1.43
142 INT174683 Transcription of Tlr2 12 0.58 5.95 1.4
143 INT56228 Positive_regulation of Positive_regulation of Ifng 2 0.43 2.83 1.4
144 INT141131 Positive_regulation of Gene_expression of PRNP 12 0.61 16.6 1.36
145 INT221131 Localization of Tlr2 17 0.80 13.82 1.28
146 INT179497 Positive_regulation of Binding of Tlr4 12 0.50 6.49 1.27
147 INT11137 Negative_regulation of Localization of Ifng 3 0.38 2.45 1.26
148 INT19923 Regulation of Localization of Ifng 3 0.22 1.1 1.25
149 INT79554 Negative_regulation of Localization of Il12a 2 0.09 1.14 1.24
150 INT109243 Regulation of Positive_regulation of IFNG 1 0.45 1.27 1.23
151 INT236329 Regulation of IL12B 3 0.02 0.78 1.2
152 INT111536 Positive_regulation of Negative_regulation of Ifng 1 0.41 0.35 1.18
153 INT190804 Positive_regulation of Tlr2 6 0.66 3.7 1.16
154 INT92055 Positive_regulation of Transcription of Il12b 4 0.49 2.77 1.16
155 INT85621 Regulation of PRNP 16 0.60 8.7 1.15
156 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12
157 INT233357 Localization of Il12b 7 0.16 3.4 1.12
158 INT67399 Negative_regulation of Transcription of Il12a 2 0.03 2.63 1.05
159 INT204737 Negative_regulation of Gene_expression of Prnp 32 0.59 18.96 1.03
160 INT122884 Positive_regulation of Transcription of Ifng 1 0.39 1.08 1.03
161 INT144232 Negative_regulation of Gene_expression of Il12b 4 0.41 2.26 1.01
162 INT118738 Transcription of Tlr4 4 0.70 1.39 1
163 INT233349 Regulation of Il12b 5 0.05 3.71 0.98
164 INT110949 Negative_regulation of Negative_regulation of Il12a 1 0.41 0 0.98
165 INT133173 Regulation of Negative_regulation of Il12b 2 0.04 0.52 0.97
166 INT77947 Regulation of Gene_expression of IL12A 6 0.24 5.23 0.94
167 INT288493 Positive_regulation of Gene_expression of Tlr2 4 0.66 4.38 0.94
168 INT145760 Binding of Tlr2 5 0.46 3.59 0.89
169 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
170 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
171 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
172 INT208243 Positive_regulation of Phosphorylation of Tlr4 5 0.31 3.74 0.86
173 INT92649 Negative_regulation of Gene_expression of IL12B 3 0.03 2.23 0.86
174 INT110027 Regulation of Localization of Il12a 3 0.41 0.6 0.85
175 INT136634 Transcription of Prnp 9 0.72 3.34 0.83
176 INT103303 Negative_regulation of Transcription of Ifng 6 0.43 2.7 0.83
177 INT43488 Regulation of Positive_regulation of Ifng 1 0.42 0.71 0.83
178 INT64635 Binding of Ifng 2 0.36 0.57 0.81
179 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
180 INT11138 Regulation of Localization of Ifng 2 0.56 0.8 0.77
181 INT73240 Negative_regulation of Transcription of IFNG 1 0.41 0.92 0.76
182 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
183 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
184 INT186283 Negative_regulation of Gene_expression of Il12b 2 0.13 7.92 0.74
185 INT224630 Positive_regulation of Positive_regulation of Tlr2 6 0.46 4.14 0.73
186 INT100601 Localization of PRNP 17 0.66 13.61 0.71
187 INT254115 Negative_regulation of Phosphorylation of Tlr4 5 0.27 3.91 0.71
188 INT228188 Regulation of Gene_expression of Tlr2 5 0.45 6.96 0.71
189 INT190662 Regulation of Positive_regulation of Prnp 4 0.24 1.15 0.7
190 INT240523 Phosphorylation of Il12a 2 0.29 1.32 0.7
191 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
192 INT69571 Positive_regulation of Positive_regulation of Prnp 6 0.70 5.88 0.67
193 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
194 INT116009 Regulation of Negative_regulation of Ifng 1 0.44 0.09 0.67
195 INT74155 Transcription of Il12b 3 0.60 1.45 0.66
196 INT156544 Regulation of Il12b 2 0.44 1.29 0.66
197 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
198 INT61622 Positive_regulation of Transcription of IFNG 1 0.26 0.29 0.63
199 INT56231 Regulation of Positive_regulation of Ifng 1 0.39 0.33 0.62
200 INT95567 Negative_regulation of Positive_regulation of IL12A 2 0.34 1.83 0.59
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