GO:0032707

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Name negative regulation of interleukin-23 production
Categary Process
Go Slim No
Go Link GO:0032707
Unique Molecular Interactions 563
Total Molecular Interactions 853
Total Single Events 4193
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of interleukin-23 production. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of interleukin-23 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
5 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
6 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
7 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
8 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
9 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
10 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
11 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
12 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
13 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
14 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
15 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
16 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
17 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
18 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
19 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
20 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
21 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
22 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
23 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
24 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
25 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
26 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
27 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
28 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
29 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
30 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
31 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
32 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
33 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
34 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
35 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
36 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
37 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
38 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
39 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
40 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
41 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
42 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
43 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
44 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
45 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
46 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
47 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
48 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
49 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
50 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
51 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
52 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
53 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64
54 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
55 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
56 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
57 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
58 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
59 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
60 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
61 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59
62 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
63 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
64 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
65 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57
66 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
67 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
68 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
69 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
70 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
71 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
72 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54
73 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54
74 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
75 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52
76 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
77 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51
78 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51
79 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
80 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49
81 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49
82 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
83 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
84 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
85 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48
86 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47
87 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
88 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
89 INT284300 Tlr4 Positive_regulation of Gene_expression of Mir155 1 0.18 0.91 0.47
90 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
91 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46
92 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46
93 INT310769 Pam Regulation of Tlr4 1 0.01 0.69 0.46
94 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
95 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
96 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
97 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
98 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42
99 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
100 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
101 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41
102 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
103 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
104 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
105 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
106 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39
107 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
108 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
109 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
110 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38
111 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
112 INT204893 Regulation of Tlr4 Positive_regulation of gr 1 0.11 0.9 0.38
113 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
114 INT147969 Binding of Ly86 and Tlr4 1 0.30 0.37 0.38
115 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
116 INT215275 Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 1.37 0.38
117 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
118 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
119 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38
120 INT204905 Tlr4 Positive_regulation of gr 1 0.18 0.9 0.38
121 INT324821 Tlr4 Positive_regulation of Gene_expression of Maob 1 0.07 0.44 0.37
122 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
123 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37
124 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
125 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
126 INT110135 Tlr4 Regulation of Localization of Gnrh1 1 0.01 0.2 0.36
127 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
128 INT337304 PTAFR Positive_regulation of Gene_expression of TLR4 1 0.62 1.99 0.36
129 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36
130 INT118743 Tlr4 Positive_regulation of Itgam 1 0.39 0.41 0.35
131 INT110132 Tlr4 Regulation of Localization of LH 1 0.01 0.2 0.35
132 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34
133 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
134 INT110134 Tlr4 Regulation of Regulation of Gnrh1 1 0.01 0.15 0.33
135 INT224691 Positive_regulation of Tlr4 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
136 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32
137 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
138 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
139 INT295198 Tlr4 Positive_regulation of Gene_expression of Ptger2 1 0.01 0.15 0.32
140 INT322016 Binding of IL1B and TLR4 1 0.05 0.18 0.32
141 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32
142 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32
143 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
144 INT276604 Tlr4 Positive_regulation of Gene_expression of Paf 1 0.22 0.37 0.31
145 INT276605 Tlr4 Positive_regulation of Gene_expression of Mthfd1 1 0.06 0.37 0.31
146 INT288198 Binding of Tlr4 and Mapk14 1 0.01 0.63 0.31
147 INT185319 Il6 Positive_regulation of Gene_expression of Tlr4 1 0.11 0.36 0.31
148 INT185322 TNF Positive_regulation of Gene_expression of Tlr4 1 0.01 0.36 0.31
149 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
150 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
151 INT306323 Tlr4 Positive_regulation of Ticam1 3 0.25 0.55 0.3
152 INT324832 Tlr4 Positive_regulation of IFNA1 1 0.05 0.46 0.3
153 INT229600 Tlr4 Positive_regulation of Il1a 1 0.00 0.41 0.3
154 INT223752 Tlr4 Positive_regulation of Il1 1 0.12 0.64 0.3
155 INT178342 Positive_regulation of Tlr4 Positive_regulation of Il6 1 0.13 0.25 0.3
156 INT306319 Cd14 Positive_regulation of Tlr4 1 0.48 0.29 0.3
157 INT168616 Tlr4 Negative_regulation of Localization of Tnf 1 0.33 0.44 0.3
158 INT354368 FGFR1 Positive_regulation of Tlr4 1 0.01 0.16 0.29
159 INT144862 Tlr4 Positive_regulation of PGE 2 0.13 0.35 0.28
160 INT215274 Tlr4 Positive_regulation of Ros1 2 0.02 1.48 0.28
161 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28
162 INT337293 PTAFR Positive_regulation of Positive_regulation of TLR4 1 0.62 1.43 0.28
163 INT339494 Eif2ak2 Positive_regulation of Tlr4 1 0.13 0.18 0.28
164 INT310255 Tlr4 Positive_regulation of Gene_expression of Cd86 2 0.18 0.06 0.27
165 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27
166 INT295197 Tlr4 Positive_regulation of Ptger2 1 0.01 0.05 0.27
167 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27
168 INT222428 Negative_regulation of Tlr4 Positive_regulation of Il6 1 0.01 0.26 0.27
169 INT222412 Cd14 Negative_regulation of Binding of Tlr4 1 0.02 0.26 0.27
170 INT222440 Tlr4 Positive_regulation of Localization of Pomc 1 0.01 0.35 0.27
171 INT118848 GNA14 Positive_regulation of RAC1 1 0.01 0.14 0.26
172 INT268766 Tlr4 Positive_regulation of Gene_expression of Ccr1 1 0.04 0.4 0.26
173 INT78067 Tlr4 Positive_regulation of Localization of Ptger2 1 0.01 0.07 0.26
174 INT290707 Binding of Tlr4 and Cd200r1 1 0.01 0.7 0.26
175 INT222422 Tlr4 Positive_regulation of Il6 1 0.01 0.25 0.26
176 INT310766 Tlr4 Positive_regulation of Cxcl2 1 0.29 0.28 0.26
177 INT306325 Tlr4 Positive_regulation of Localization of Cd14 1 0.39 0.37 0.26
178 INT295200 Hspg2 Positive_regulation of Tlr4 1 0.00 0 0.25
179 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25
180 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25
181 INT350074 Binding of Tlr4 and Myadm 1 0.00 0.5 0.25
182 INT343864 EDA Positive_regulation of Gene_expression of TLR4 1 0.11 0.44 0.25
183 INT222421 Tlr4 Negative_regulation of Localization of Prl 1 0.02 0.45 0.25
184 INT343931 Hapln1 Negative_regulation of Tlr4 1 0.12 0.42 0.25
185 INT350079 Tlr4 Positive_regulation of Ptger2 1 0.01 0.57 0.25
186 INT321224 TLR4 Positive_regulation of NFKB1 1 0.04 1.02 0.25
187 INT324694 Tlr4 Positive_regulation of Gene_expression of Pnoc 1 0.05 0.56 0.24
188 INT242875 INS Negative_regulation of Gene_expression of TLR4 1 0.11 1.41 0.24
189 INT221383 Tlr4 Positive_regulation of Localization of Ptger2 1 0.00 1.78 0.23
190 INT339509 Tlr4 Regulation of Eif2ak2 1 0.08 0.16 0.23
191 INT110133 Tlr4 Regulation of Gene_expression of Fos 1 0.01 0.23 0.23
192 INT292561 MAP3K5 Positive_regulation of Positive_regulation of RAC1 1 0.03 0 0.23
193 INT238383 Tlr4 Positive_regulation of Ppara 1 0.17 0.41 0.23
194 INT175317 Hsp90b1 Positive_regulation of Tlr4 1 0.02 0.66 0.23
195 INT191885 Tlr4 Regulation of Phosphorylation of Mapk3 1 0.01 0.24 0.23
196 INT266418 Binding of HMGB1 and Tlr4 1 0.09 0.37 0.23
197 INT165919 Tlr4 Positive_regulation of Positive_regulation of Nfkb1 1 0.16 0.55 0.23
198 INT339501 Binding of Eif2ak2 and Tlr4 1 0.14 0.19 0.23
199 INT208084 Tlr4 Positive_regulation of Eps8l1 1 0.00 0.5 0.23
200 INT292556 Binding of F2RL1 and TLR4 1 0.05 0.52 0.22

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of interleukin-23 production. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of interleukin-23 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
2 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
3 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
4 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
5 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
6 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
7 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
8 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
9 INT134651 Binding of TLR4 89 0.48 66.96 23.19
10 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
11 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
12 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
13 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
14 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
15 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
16 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
17 INT27627 Binding of Rac1 41 0.41 22.88 13.68
18 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
19 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
20 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
21 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
22 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
23 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
24 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
25 INT97797 Localization of TLR4 18 0.77 13.78 6
26 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
27 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
28 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54
29 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
30 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
31 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
32 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75
33 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
34 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
35 INT121967 Regulation of RAC1 9 0.45 6.14 3.41
36 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
37 INT58475 Localization of Rac1 12 0.75 5.94 3.2
38 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
39 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
40 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
41 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
42 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
43 INT70987 Binding of RAC1 14 0.37 12.14 2.13
44 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
45 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
46 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
47 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
48 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
49 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74
50 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
51 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4
52 INT179497 Positive_regulation of Binding of Tlr4 12 0.50 6.49 1.27
53 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21
54 INT98062 Regulation of Gene_expression of Rac1 4 0.39 1.41 1.21
55 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13
56 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12
57 INT118738 Transcription of Tlr4 4 0.70 1.39 1
58 INT67174 Negative_regulation of Rac1 22 0.56 10.72 0.99
59 INT81211 Transcription of Rac1 4 0.54 1.05 0.89
60 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
61 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
62 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
63 INT175904 Localization of RAC1 7 0.41 5.05 0.86
64 INT208243 Positive_regulation of Phosphorylation of Tlr4 5 0.31 3.74 0.86
65 INT111943 Negative_regulation of Positive_regulation of RAC1 2 0.46 1.33 0.86
66 INT330097 Positive_regulation of Positive_regulation of Rac1 1 0.37 2.47 0.86
67 INT264629 Localization of Rac1 8 0.72 5.7 0.79
68 INT111945 Protein_catabolism of RAC1 1 0.31 0.67 0.79
69 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
70 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
71 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
72 INT254115 Negative_regulation of Phosphorylation of Tlr4 5 0.27 3.91 0.71
73 INT115596 Regulation of Regulation of Rac1 1 0.36 0.29 0.7
74 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
75 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
76 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
77 INT147734 Phosphorylation of RAC1 3 0.64 1.33 0.58
78 INT228103 Positive_regulation of Rac1 25 0.67 18.92 0.57
79 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57
80 INT204864 Negative_regulation of Negative_regulation of Tlr4 3 0.30 2.05 0.56
81 INT16012 Binding of Rac1 17 0.37 6.9 0.53
82 INT127736 Regulation of Gene_expression of RAC1 2 0.27 2 0.53
83 INT246926 Negative_regulation of Transcription of Tlr4 3 0.41 1.78 0.49
84 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49
85 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47
86 INT152229 Positive_regulation of Regulation of Tlr4 2 0.40 0.29 0.46
87 INT164267 Negative_regulation of Phosphorylation of RAC1 1 0.33 0.96 0.46
88 INT81212 Negative_regulation of Transcription of Rac1 1 0.01 0 0.46
89 INT164266 Positive_regulation of Phosphorylation of RAC1 1 0.39 0.95 0.45
90 INT87847 Regulation of Positive_regulation of Rac1 2 0.36 1.49 0.43
91 INT185313 Regulation of Transcription of Tlr4 3 0.20 0.49 0.39
92 INT178182 Negative_regulation of Binding of Tlr4 3 0.33 2.13 0.38
93 INT118736 Positive_regulation of Transcription of Tlr4 1 0.49 0.42 0.35
94 INT124986 Positive_regulation of Localization of Rac1 3 0.50 1.22 0.33
95 INT230494 Regulation of Binding of Tlr4 3 0.45 2.97 0.31
96 INT112551 Protein_catabolism of Rac1 2 0.66 0.29 0.3
97 INT116729 Regulation of Localization of Rac1 1 0.01 0.07 0.29
98 INT99682 Phosphorylation of Rac1 1 0.54 0.72 0.28
99 INT157768 Negative_regulation of Binding of TLR4 1 0.43 0.29 0.27
100 INT162873 Negative_regulation of Negative_regulation of Rac1 1 0.34 0.35 0.26
101 INT204866 Regulation of Localization of Tlr4 3 0.37 0.66 0.25
102 INT330090 Regulation of Negative_regulation of Rac1 1 0.36 0.53 0.25
103 INT330093 Negative_regulation of Positive_regulation of Rac1 1 0.34 0.88 0.23
104 INT215080 Positive_regulation of Negative_regulation of Tlr4 1 0.31 0.05 0.23
105 INT301950 Regulation of Regulation of Tlr4 1 0.40 0.32 0.23
106 INT348772 Positive_regulation of Positive_regulation of Tlr4 1 0.61 0.72 0.21
107 INT334246 Positive_regulation of Protein_catabolism of Tlr4 1 0.07 0.18 0.18
108 INT306008 Positive_regulation of Transcription of Tlr4 2 0.50 1.41 0.16
109 INT168055 Regulation of Transcription of Rac1 1 0.36 0.34 0.16
110 INT133599 Positive_regulation of Binding of Rac1 2 0.40 0.4 0.15
111 INT330085 Regulation of Binding of Rac1 1 0.36 0.28 0.15
112 INT285435 Protein_catabolism of TLR4 2 0.62 0.9 0.14
113 INT246424 Negative_regulation of Transcription of TLR4 2 0.41 0.52 0.14
114 INT282160 Regulation of Binding of RAC1 1 0.18 0.45 0.13
115 INT285441 Regulation of Localization of TLR4 2 0.38 0.15 0.12
116 INT302613 Positive_regulation of Gene_expression of Rac1 14 0.67 3.7 0.08
117 INT176593 Positive_regulation of Gene_expression of RAC1 2 0.17 0.97 0.08
118 INT334443 Positive_regulation of Positive_regulation of Rac1 1 0.33 1.1 0.08
119 INT159858 Negative_regulation of Negative_regulation of RAC1 1 0.40 0.17 0.07
120 INT302624 Negative_regulation of Gene_expression of Rac1 1 0.56 3.67 0.06
121 INT276930 Regulation of Regulation of Tlr4 1 0.17 0.45 0.05
122 INT242899 Negative_regulation of Negative_regulation of TLR4 1 0.20 0.09 0.05
123 INT323949 Negative_regulation of Positive_regulation of Rac1 1 0.23 0.53 0.05
124 INT184726 Negative_regulation of Protein_catabolism of Tlr4 2 0.36 0.21 0.04
125 INT334445 Regulation of Positive_regulation of Rac1 1 0.40 1.73 0.04
126 INT254550 Negative_regulation of Gene_expression of RAC1 1 0.13 0.63 0.04
127 INT254537 Negative_regulation of Binding of RAC1 1 0.13 0.64 0.04
128 INT231780 Regulation of Transcription of TLR4 1 0.19 0.62 0.04
129 INT302611 Regulation of Gene_expression of Rac1 1 0.43 4.5 0.03
130 INT206165 Positive_regulation of Localization of RAC1 1 0.16 0.07 0.03
131 INT302615 Transcription of Rac1 5 0.66 1.1 0
132 INT334450 Regulation of Localization of Rac1 1 0.30 0.65 0
133 INT228095 Phosphorylation of Rac1 1 0.34 0.21 0
134 INT302609 Positive_regulation of Transcription of Rac1 1 0.48 0.27 0
135 INT302631 Regulation of Transcription of Rac1 1 0.43 0.47 0
136 INT257362 Negative_regulation of Localization of RAC1 1 0.24 0.58 0
137 INT302621 Regulation of Negative_regulation of Rac1 1 0.43 0 0
138 INT302627 Negative_regulation of Localization of Rac1 1 0.41 0.28 0
139 INT337311 Negative_regulation of Positive_regulation of TLR4 1 0.35 0 0
140 INT302620 Negative_regulation of Transcription of Rac1 1 0.41 0 0
141 INT334438 Positive_regulation of Localization of Rac1 1 0.33 2.37 0
142 INT295687 Positive_regulation of Binding of RAC1 1 0.25 0 0
143 INT295678 Regulation of Positive_regulation of RAC1 1 0.23 1.55 0
144 INT254786 Positive_regulation of Negative_regulation of Rac1 1 0.26 0.95 0
145 INT302614 Positive_regulation of Binding of Rac1 1 0.48 0.31 0
146 INT151565 Negative_regulation of Transcription of Tlr4 1 0.41 0.08 0
147 INT184727 Regulation of Protein_catabolism of Tlr4 1 0.38 0.17 0
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