GO:0032728

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Name positive regulation of interferon-beta production
Categary Process
Go Slim No
Go Link GO:0032728
Unique Molecular Interactions 723
Total Molecular Interactions 1093
Total Single Events 5341
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interferon-beta production. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interferon-beta production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
5 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
6 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
7 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
8 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
9 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
10 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
11 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
12 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
13 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
14 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
15 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
16 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
17 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
18 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
19 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
20 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
21 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
22 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
23 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
24 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04
25 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
26 INT174910 Binding of LBP and IFIH1 1 0.04 1.01 1.01
27 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
28 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94
29 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
30 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
31 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
32 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
33 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
34 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89
35 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
36 INT116771 Binding of MAVS and MRGPRX1 1 0.00 0.51 0.89
37 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
38 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
39 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
40 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83
41 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
42 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79
43 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
44 INT296787 Tbrs1 Positive_regulation of Gene_expression of Tlr9 1 0.06 1.37 0.78
45 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
46 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
47 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
48 INT296788 Tlr9 Regulation of Positive_regulation of Il1 1 0.07 1.37 0.77
49 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
50 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
51 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
52 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
53 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
54 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
55 INT116020 Positive_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
56 INT116021 Binding of Il4 and Mavs 1 0.02 0.08 0.7
57 INT116019 Negative_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
58 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
59 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
60 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
61 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
62 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
63 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
64 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
65 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
66 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64
67 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
68 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
69 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
70 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
71 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
72 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
73 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59
74 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
75 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
76 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
77 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
78 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57
79 INT263975 NR4A3 Negative_regulation of Positive_regulation of TBK1 1 0.02 1.2 0.57
80 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
81 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
82 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56
83 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
84 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
85 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
86 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
87 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54
88 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54
89 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
90 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
91 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52
92 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
93 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51
94 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51
95 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
96 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49
97 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49
98 INT158599 Tlr3 Positive_regulation of Binding of Fas 1 0.55 0.86 0.48
99 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
100 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48
101 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47
102 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
103 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
104 INT284300 Tlr4 Positive_regulation of Gene_expression of Mir155 1 0.18 0.91 0.47
105 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
106 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46
107 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46
108 INT310769 Pam Regulation of Tlr4 1 0.01 0.69 0.46
109 INT296795 Binding of Tlr9 and Tlr3 2 0.22 1.29 0.45
110 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44
111 INT304281 IL8 Positive_regulation of TBK1 1 0.01 2.35 0.44
112 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
113 INT230461 Binding of TLR1 and TLR2 3 0.33 2.06 0.43
114 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
115 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
116 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42
117 INT185381 TNF Regulation of TLR2 2 0.31 1.9 0.41
118 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41
119 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41
120 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41
121 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
122 INT348031 Binding of Irf3 and Tbk1 1 0.17 2.82 0.4
123 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
124 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
125 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39
126 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
127 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
128 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
129 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
130 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38
131 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
132 INT204893 Regulation of Tlr4 Positive_regulation of gr 1 0.11 0.9 0.38
133 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
134 INT147969 Binding of Ly86 and Tlr4 1 0.30 0.37 0.38
135 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
136 INT215275 Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 1.37 0.38
137 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
138 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
139 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38
140 INT204905 Tlr4 Positive_regulation of gr 1 0.18 0.9 0.38
141 INT324821 Tlr4 Positive_regulation of Gene_expression of Maob 1 0.07 0.44 0.37
142 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
143 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37
144 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
145 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
146 INT110135 Tlr4 Regulation of Localization of Gnrh1 1 0.01 0.2 0.36
147 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
148 INT337304 PTAFR Positive_regulation of Gene_expression of TLR4 1 0.62 1.99 0.36
149 INT306254 Binding of TLR2 and LY96 1 0.25 1.29 0.36
150 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36
151 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35
152 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35
153 INT118743 Tlr4 Positive_regulation of Itgam 1 0.39 0.41 0.35
154 INT110132 Tlr4 Regulation of Localization of LH 1 0.01 0.2 0.35
155 INT310765 Binding of Pam and Tlr2 1 0.01 0.57 0.35
156 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34
157 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34
158 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34
159 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34
160 INT288200 Tlr2 Positive_regulation of Pik3r1 1 0.05 0.24 0.33
161 INT110134 Tlr4 Regulation of Regulation of Gnrh1 1 0.01 0.15 0.33
162 INT224691 Positive_regulation of Tlr4 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
163 INT224681 Tlr2 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
164 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32
165 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32
166 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
167 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32
168 INT295198 Tlr4 Positive_regulation of Gene_expression of Ptger2 1 0.01 0.15 0.32
169 INT322016 Binding of IL1B and TLR4 1 0.05 0.18 0.32
170 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32
171 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32
172 INT276604 Tlr4 Positive_regulation of Gene_expression of Paf 1 0.22 0.37 0.31
173 INT276605 Tlr4 Positive_regulation of Gene_expression of Mthfd1 1 0.06 0.37 0.31
174 INT288198 Binding of Tlr4 and Mapk14 1 0.01 0.63 0.31
175 INT185319 Il6 Positive_regulation of Gene_expression of Tlr4 1 0.11 0.36 0.31
176 INT185322 TNF Positive_regulation of Gene_expression of Tlr4 1 0.01 0.36 0.31
177 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31
178 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
179 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31
180 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31
181 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
182 INT306323 Tlr4 Positive_regulation of Ticam1 3 0.25 0.55 0.3
183 INT324832 Tlr4 Positive_regulation of IFNA1 1 0.05 0.46 0.3
184 INT229600 Tlr4 Positive_regulation of Il1a 1 0.00 0.41 0.3
185 INT223752 Tlr4 Positive_regulation of Il1 1 0.12 0.64 0.3
186 INT178342 Positive_regulation of Tlr4 Positive_regulation of Il6 1 0.13 0.25 0.3
187 INT306319 Cd14 Positive_regulation of Tlr4 1 0.48 0.29 0.3
188 INT168616 Tlr4 Negative_regulation of Localization of Tnf 1 0.33 0.44 0.3
189 INT137159 Binding of TLR7 and TLR9 1 0.27 0.33 0.29
190 INT137163 Binding of TLR5 and TLR9 1 0.25 0.33 0.29
191 INT354368 FGFR1 Positive_regulation of Tlr4 1 0.01 0.16 0.29
192 INT144862 Tlr4 Positive_regulation of PGE 2 0.13 0.35 0.28
193 INT215274 Tlr4 Positive_regulation of Ros1 2 0.02 1.48 0.28
194 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28
195 INT337293 PTAFR Positive_regulation of Positive_regulation of TLR4 1 0.62 1.43 0.28
196 INT339494 Eif2ak2 Positive_regulation of Tlr4 1 0.13 0.18 0.28
197 INT193479 TLR2 Regulation of Binding of IRF6 1 0.04 0.75 0.28
198 INT310255 Tlr4 Positive_regulation of Gene_expression of Cd86 2 0.18 0.06 0.27
199 INT276953 Positive_regulation of Tlr2 Positive_regulation of Phosphorylation of Stat3 1 0.38 0.93 0.27
200 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interferon-beta production. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interferon-beta production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
2 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
3 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
4 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
5 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
6 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
7 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
8 INT134651 Binding of TLR4 89 0.48 66.96 23.19
9 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
10 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
11 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
12 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
13 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
14 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
15 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
16 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
17 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
18 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
19 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
20 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65
21 INT150540 Binding of TLR2 50 0.45 35.86 10.43
22 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05
23 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
24 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
25 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
26 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
27 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67
28 INT207892 Binding of Tlr9 35 0.46 26.66 6.61
29 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4
30 INT97797 Localization of TLR4 18 0.77 13.78 6
31 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
32 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
33 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
34 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43
35 INT97145 Positive_regulation of TBK1 14 0.12 15.32 5.43
36 INT183467 Negative_regulation of TBK1 6 0.12 9.89 5.41
37 INT174688 Binding of Tlr2 45 0.42 36.65 5.25
38 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
39 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18
40 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
41 INT185398 Negative_regulation of Gene_expression of TLR2 34 0.55 27.21 4.73
42 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54
43 INT188672 Positive_regulation of Tlr9 15 0.67 13.1 4.48
44 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
45 INT149986 Positive_regulation of Gene_expression of Tlr9 5 0.67 8.18 4.15
46 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07
47 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99
48 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
49 INT158596 Binding of Tlr3 24 0.47 11.66 3.69
50 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
51 INT264970 Positive_regulation of Localization of TLR2 1 0.11 4.21 3.37
52 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
53 INT186805 Transcription of TLR2 12 0.63 9.66 3.04
54 INT92335 Gene_expression of TBK1 11 0.28 8.98 3
55 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
56 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
57 INT260424 Negative_regulation of Tlr9 8 0.41 8.19 2.92
58 INT204524 Binding of TLR9 17 0.43 11.69 2.76
59 INT97132 Negative_regulation of Positive_regulation of TBK1 5 0.08 6.54 2.76
60 INT133029 Regulation of TLR2 18 0.56 11.31 2.62
61 INT186799 Localization of TLR2 5 0.68 2.51 2.58
62 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
63 INT183468 Localization of TBK1 6 0.32 4.35 2.36
64 INT99524 Gene_expression of IFIH1 34 0.64 23.38 2.24
65 INT204775 Regulation of Tlr2 21 0.41 13.6 2.18
66 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
67 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
68 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
69 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
70 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74
71 INT228195 Negative_regulation of Gene_expression of Tlr2 14 0.40 12.17 1.74
72 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
73 INT175307 Regulation of Gene_expression of TLR2 9 0.56 7.08 1.58
74 INT204530 Positive_regulation of Gene_expression of TLR9 14 0.70 6.85 1.48
75 INT258048 Regulation of TBK1 4 0.05 3.81 1.44
76 INT174683 Transcription of Tlr2 12 0.58 5.95 1.4
77 INT186810 Positive_regulation of TLR3 13 0.65 6.37 1.37
78 INT150730 Regulation of Tlr3 2 0.45 6.51 1.37
79 INT221131 Localization of Tlr2 17 0.80 13.82 1.28
80 INT179497 Positive_regulation of Binding of Tlr4 12 0.50 6.49 1.27
81 INT151567 Gene_expression of Tlr9 6 0.72 3.63 1.26
82 INT146914 Negative_regulation of TLR2 12 0.53 7.41 1.23
83 INT190804 Positive_regulation of Tlr2 6 0.66 3.7 1.16
84 INT183790 Binding of TBK1 2 0.04 2.97 1.16
85 INT150729 Negative_regulation of Tlr3 3 0.43 3.26 1.14
86 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12
87 INT186807 Positive_regulation of Gene_expression of TLR3 8 0.53 7.19 1.08
88 INT288489 Transcription of Tlr3 1 0.51 3.85 1.05
89 INT118738 Transcription of Tlr4 4 0.70 1.39 1
90 INT288483 Gene_expression of Tlr3 8 0.72 4.51 0.97
91 INT288493 Positive_regulation of Gene_expression of Tlr2 4 0.66 4.38 0.94
92 INT145760 Binding of Tlr2 5 0.46 3.59 0.89
93 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
94 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
95 INT188575 Positive_regulation of Transcription of TLR2 1 0.30 1.37 0.88
96 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
97 INT208243 Positive_regulation of Phosphorylation of Tlr4 5 0.31 3.74 0.86
98 INT263481 Regulation of Positive_regulation of TBK1 1 0.07 1.28 0.81
99 INT186804 Binding of TLR3 14 0.45 8.41 0.79
100 INT352771 Positive_regulation of Localization of TBK1 1 0.05 0.98 0.78
101 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
102 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
103 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
104 INT294787 Localization of TLR9 2 0.67 2.35 0.75
105 INT224630 Positive_regulation of Positive_regulation of Tlr2 6 0.46 4.14 0.73
106 INT254115 Negative_regulation of Phosphorylation of Tlr4 5 0.27 3.91 0.71
107 INT228188 Regulation of Gene_expression of Tlr2 5 0.45 6.96 0.71
108 INT331594 Localization of Tlr9 1 0.41 1.66 0.71
109 INT331595 Positive_regulation of Localization of Tlr9 1 0.28 1.66 0.71
110 INT255974 Transcription of Tlr3 10 0.49 6.11 0.7
111 INT186798 Regulation of TLR3 5 0.42 3.13 0.69
112 INT314571 Binding of Tbk1 3 0.24 2.88 0.69
113 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
114 INT116007 Negative_regulation of Mavs 1 0.03 0.08 0.69
115 INT186801 Positive_regulation of Binding of TLR2 3 0.42 2.05 0.67
116 INT333595 Negative_regulation of Gene_expression of TBK1 2 0.12 0.91 0.67
117 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
118 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
119 INT290394 Negative_regulation of Positive_regulation of TLR2 4 0.34 2.8 0.65
120 INT296782 Phosphorylation of Tlr9 1 0.61 0.53 0.63
121 INT180531 Positive_regulation of Positive_regulation of TLR2 4 0.32 4.28 0.62
122 INT188775 Binding of IFIH1 11 0.16 12.4 0.61
123 INT204525 Negative_regulation of Gene_expression of TLR3 2 0.54 1.8 0.61
124 INT288485 Regulation of Transcription of Tlr3 1 0.20 0.85 0.61
125 INT246423 Negative_regulation of TLR3 1 0.40 2.2 0.6
126 INT254177 Positive_regulation of Positive_regulation of Tlr3 3 0.41 2.06 0.58
127 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57
128 INT204864 Negative_regulation of Negative_regulation of Tlr4 3 0.30 2.05 0.56
129 INT183685 Positive_regulation of Gene_expression of Tlr3 4 0.61 1.5 0.53
130 INT190864 Positive_regulation of Phosphorylation of Tbk1 1 0.08 0.68 0.53
131 INT234597 Negative_regulation of Positive_regulation of Tlr2 2 0.30 2.25 0.52
132 INT190859 Phosphorylation of Tbk1 1 0.12 0.68 0.52
133 INT234587 Positive_regulation of Transcription of Tlr2 3 0.36 1.84 0.51
134 INT288490 Binding of Tlr9 1 0.25 1.88 0.51
135 INT246926 Negative_regulation of Transcription of Tlr4 3 0.41 1.78 0.49
136 INT188677 Positive_regulation of Positive_regulation of Tlr9 2 0.29 1.22 0.49
137 INT200677 Transcription of TBK1 2 0.14 0.74 0.49
138 INT84573 Regulation of Mavs 1 0.01 1.37 0.49
139 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49
140 INT313688 Regulation of IFIH1 3 0.19 4.2 0.48
141 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47
142 INT152229 Positive_regulation of Regulation of Tlr4 2 0.40 0.29 0.46
143 INT263479 Positive_regulation of Transcription of TBK1 1 0.12 0.32 0.46
144 INT183470 Positive_regulation of Negative_regulation of TBK1 1 0.08 0.46 0.46
145 INT166728 Regulation of MAVS 1 0.32 0.15 0.44
146 INT325457 Negative_regulation of Binding of TLR2 1 0.04 1.3 0.43
147 INT346479 Positive_regulation of DDX58 1 0.06 5.3 0.42
148 INT237905 Positive_regulation of Binding of Tlr3 1 0.30 0.79 0.42
149 INT204533 Regulation of Gene_expression of TLR9 8 0.55 2.81 0.4
150 INT183680 Localization of Tlr3 6 0.71 1.69 0.39
151 INT47625 Negative_regulation of IFIH1 4 0.51 1.68 0.39
152 INT185313 Regulation of Transcription of Tlr4 3 0.20 0.49 0.39
153 INT219171 Negative_regulation of Positive_regulation of TLR9 1 0.18 1.3 0.39
154 INT178182 Negative_regulation of Binding of Tlr4 3 0.33 2.13 0.38
155 INT182134 Transcription of TLR9 2 0.72 1.21 0.37
156 INT284455 Regulation of Gene_expression of Tlr9 1 0.30 1.19 0.37
157 INT188776 Positive_regulation of IFIH1 10 0.23 9.93 0.35
158 INT118736 Positive_regulation of Transcription of Tlr4 1 0.49 0.42 0.35
159 INT246419 Positive_regulation of Negative_regulation of TLR3 1 0.43 0.67 0.34
160 INT230494 Regulation of Binding of Tlr4 3 0.45 2.97 0.31
161 INT346492 Protein_catabolism of MAVS 1 0.06 1.74 0.31
162 INT329061 Positive_regulation of Tlr9 1 0.47 2.05 0.29
163 INT314573 Positive_regulation of Binding of Tbk1 1 0.30 0.14 0.29
164 INT152643 Positive_regulation of Gene_expression of IFIH1 5 0.42 5.2 0.28
165 INT288189 Negative_regulation of Negative_regulation of Tlr2 1 0.26 0.43 0.28
166 INT331590 Negative_regulation of Binding of Tlr9 1 0.24 1.52 0.28
167 INT204528 Negative_regulation of Gene_expression of TLR9 5 0.52 4.47 0.27
168 INT236357 Negative_regulation of Positive_regulation of Tlr9 2 0.33 3.1 0.27
169 INT157768 Negative_regulation of Binding of TLR4 1 0.43 0.29 0.27
170 INT288186 Regulation of Binding of Tlr2 2 0.32 1.72 0.26
171 INT224614 Regulation of Positive_regulation of Tlr2 1 0.13 0.56 0.26
172 INT204866 Regulation of Localization of Tlr4 3 0.37 0.66 0.25
173 INT112834 Regulation of Gene_expression of IFIH1 1 0.08 0.15 0.25
174 INT204531 Negative_regulation of TLR9 1 0.43 1.29 0.25
175 INT145758 Regulation of Tlr2 3 0.43 0.94 0.23
176 INT145761 Negative_regulation of Tlr2 2 0.41 1.97 0.23
177 INT215080 Positive_regulation of Negative_regulation of Tlr4 1 0.31 0.05 0.23
178 INT301950 Regulation of Regulation of Tlr4 1 0.40 0.32 0.23
179 INT294788 Regulation of Positive_regulation of TLR2 2 0.36 1.41 0.21
180 INT348772 Positive_regulation of Positive_regulation of Tlr4 1 0.61 0.72 0.21
181 INT186803 Transcription of TLR3 6 0.67 1.54 0.2
182 INT347982 Negative_regulation of Tbk1 1 0.28 1.41 0.2
183 INT347991 Gene_expression of Tbk1 1 0.43 1.42 0.2
184 INT254194 Regulation of Positive_regulation of Tlr3 2 0.52 0.79 0.19
185 INT288491 Positive_regulation of Transcription of Tlr3 1 0.37 1.85 0.19
186 INT334246 Positive_regulation of Protein_catabolism of Tlr4 1 0.07 0.18 0.18
187 INT306008 Positive_regulation of Transcription of Tlr4 2 0.50 1.41 0.16
188 INT294633 Positive_regulation of Binding of Tlr2 1 0.44 0.42 0.16
189 INT336418 Negative_regulation of Binding of Tlr3 1 0.36 0.59 0.16
190 INT204974 Positive_regulation of Mavs 1 0.02 3.77 0.16
191 INT204989 Gene_expression of Mavs 3 0.02 0.86 0.15
192 INT350779 Positive_regulation of Positive_regulation of TLR9 1 0.08 0.8 0.15
193 INT346493 Binding of MAVS 1 0.03 0.54 0.15
194 INT145759 Regulation of Gene_expression of Tlr2 3 0.43 0.98 0.14
195 INT285435 Protein_catabolism of TLR4 2 0.62 0.9 0.14
196 INT246424 Negative_regulation of Transcription of TLR4 2 0.41 0.52 0.14
197 INT301958 Positive_regulation of Regulation of Tlr2 1 0.21 0.32 0.13
198 INT204527 Regulation of TLR9 7 0.40 2.88 0.12
199 INT279781 Gene_expression of MAVS 4 0.15 3.51 0.12
200 INT285441 Regulation of Localization of TLR4 2 0.38 0.15 0.12
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