GO:0032741

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Name positive regulation of interleukin-18 production
Categary Process
Go Slim No
Go Link GO:0032741
Unique Molecular Interactions 284
Total Molecular Interactions 407
Total Single Events 3842
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-18 production. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interleukin-18 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
2 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
3 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
4 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
5 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
6 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
7 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
8 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
9 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
10 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
11 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
12 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
13 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
14 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
15 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
16 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
17 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
18 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
19 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04
20 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
21 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
22 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
23 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
24 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
25 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
26 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89
27 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
28 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
29 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
30 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
31 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79
32 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
33 INT296787 Tbrs1 Positive_regulation of Gene_expression of Tlr9 1 0.06 1.37 0.78
34 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
35 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
36 INT296788 Tlr9 Regulation of Positive_regulation of Il1 1 0.07 1.37 0.77
37 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
38 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
39 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
40 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
41 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
42 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
43 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
44 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
45 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
46 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
47 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
48 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
49 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
50 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
51 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
52 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
53 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
54 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
55 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
56 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
57 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
58 INT96241 Il13 Negative_regulation of Tnf 1 0.08 0.6 0.59
59 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
60 INT61827 Tnf Regulation of Lta 1 0.40 1.5 0.58
61 INT94506 Tnf Positive_regulation of Gene_expression of Avp 1 0.31 0.98 0.57
62 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
63 INT94507 Tnf Positive_regulation of Gene_expression of AVP 1 0.39 0.98 0.57
64 INT8402 Tnf Regulation of Gene_expression of Vip 1 0.02 0.38 0.56
65 INT8400 Tnf Regulation of Gene_expression of Nts 1 0.00 0.38 0.56
66 INT148922 Pdia4 Negative_regulation of Tnf 1 0.09 1.01 0.56
67 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
68 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
69 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55
70 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54
71 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54
72 INT8397 Tnf Regulation of Nts 1 0.00 0.38 0.53
73 INT8398 Tnf Regulation of Vip 1 0.01 0.38 0.53
74 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
75 INT206960 Lipg Regulation of Tnf 1 0.02 0.85 0.51
76 INT23090 Tnf Positive_regulation of Localization of Prl 1 0.18 0.15 0.5
77 INT23091 Tnf Positive_regulation of Localization of Ggh 1 0.05 0.15 0.5
78 INT23092 Tnf Positive_regulation of Prl 1 0.08 0.15 0.5
79 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5
80 INT23089 Tnf Positive_regulation of Ggh 1 0.04 0.15 0.5
81 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
82 INT285344 Il10 Negative_regulation of Gene_expression of Tnf 1 0.15 1.91 0.49
83 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
84 INT155621 Tnf Regulation of Transcription of Il1b 1 0.51 0.77 0.49
85 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
86 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
87 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
88 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46
89 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46
90 INT296795 Binding of Tlr9 and Tlr3 2 0.22 1.29 0.45
91 INT96245 Negative_regulation of Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
92 INT96246 Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
93 INT148635 Abat Negative_regulation of Gene_expression of Tnf 1 0.10 0.53 0.44
94 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44
95 INT230461 Binding of TLR1 and TLR2 3 0.33 2.06 0.43
96 INT107694 Tnf Positive_regulation of Gene_expression of Cxcl1 1 0.60 0.63 0.43
97 INT142273 KITLG Positive_regulation of Gene_expression of Tnf 1 0.07 0.9 0.43
98 INT51475 Binding of Il6 and Tnf 1 0.15 0.61 0.43
99 INT185381 TNF Regulation of TLR2 2 0.31 1.9 0.41
100 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41
101 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41
102 INT134761 Ghrl Regulation of Localization of Tnf 1 0.20 0.76 0.4
103 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
104 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
105 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37
106 INT138515 Drd3 Negative_regulation of Localization of Tnf 1 0.06 0.4 0.36
107 INT306254 Binding of TLR2 and LY96 1 0.25 1.29 0.36
108 INT112618 Pdpk1 Regulation of Tnf 1 0.03 1.11 0.36
109 INT112620 Mapk9 Regulation of Tnf 1 0.16 1.11 0.36
110 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35
111 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35
112 INT334393 IL6 Positive_regulation of Tnf 1 0.16 1.41 0.35
113 INT310765 Binding of Pam and Tlr2 1 0.01 0.57 0.35
114 INT288200 Tlr2 Positive_regulation of Pik3r1 1 0.05 0.24 0.33
115 INT224681 Tlr2 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
116 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32
117 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32
118 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32
119 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32
120 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31
121 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31
122 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31
123 INT9162 Tnf Negative_regulation of Localization of Penk 1 0.34 0.85 0.3
124 INT9161 Tnf Negative_regulation of Localization of Ifng 1 0.20 0.85 0.3
125 INT137159 Binding of TLR7 and TLR9 1 0.27 0.33 0.29
126 INT137163 Binding of TLR5 and TLR9 1 0.25 0.33 0.29
127 INT159964 Tnf Positive_regulation of Phosphorylation of Mapk8 1 0.11 0.94 0.29
128 INT193479 TLR2 Regulation of Binding of IRF6 1 0.04 0.75 0.28
129 INT276953 Positive_regulation of Tlr2 Positive_regulation of Phosphorylation of Stat3 1 0.38 0.93 0.27
130 INT276979 Positive_regulation of Tlr2 Positive_regulation of Gene_expression of Stat3 1 0.38 0.93 0.27
131 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27
132 INT288497 Binding of Tlr7 and Tlr9 1 0.21 0.97 0.27
133 INT114389 Csf3 Negative_regulation of Localization of Tnf 1 0.02 0.46 0.26
134 INT135965 Calca Negative_regulation of Gene_expression of Tnf 1 0.33 0.72 0.26
135 INT296794 Positive_regulation of Tlr2 Positive_regulation of Pik3r1 1 0.10 1.02 0.26
136 INT230460 Binding of TLR2 and TLR6 2 0.07 1.9 0.25
137 INT114388 Csf3 Negative_regulation of Tnf 1 0.02 0.46 0.25
138 INT66257 Negative_regulation of Ptgs1 Positive_regulation of Gene_expression of Tnf 1 0.03 0.44 0.25
139 INT136364 Cpz Positive_regulation of Localization of Tnf 1 0.29 0.36 0.25
140 INT114390 Regulation of Csf3 Negative_regulation of Tnf 1 0.02 0.46 0.25
141 INT276974 Tlr2 Positive_regulation of Gene_expression of Ccr8 1 0.27 0.16 0.24
142 INT308817 Ldha Positive_regulation of Tnf 1 0.06 0.71 0.24
143 INT308818 Got1 Positive_regulation of Tnf 1 0.08 0.71 0.24
144 INT334256 Binding of Tlr9 and Iars 1 0.02 0.68 0.24
145 INT276952 Tlr2 Positive_regulation of Localization of Hspd1 1 0.25 0.16 0.24
146 INT308816 Gpt Positive_regulation of Tnf 1 0.08 0.72 0.24
147 INT175324 Hsp90b1 Positive_regulation of TLR2 1 0.00 0.65 0.23
148 INT290378 NOD2 Negative_regulation of TLR2 1 0.27 0.83 0.23
149 INT290377 NOD2 Negative_regulation of Positive_regulation of TLR2 1 0.24 0.95 0.23
150 INT285341 Mtx1 Regulation of Gene_expression of Tnf 1 0.03 0.78 0.22
151 INT133163 Nos2 Regulation of Tnf 1 0.36 0.97 0.22
152 INT285340 Mtx1 Regulation of Tnf 1 0.03 0.78 0.22
153 INT133166 ELANE Regulation of Tnf 1 0.01 0.98 0.22
154 INT133164 Ptgs2 Regulation of Tnf 1 0.14 0.98 0.22
155 INT88023 Tnf Negative_regulation of Gene_expression of Fas 1 0.29 0.74 0.22
156 INT136366 MCPH1 Regulation of Localization of Tnf 1 0.01 0.26 0.22
157 INT266380 Binding of Tlr2 and Il1 1 0.01 0.76 0.21
158 INT260440 Negative_regulation of Tlr9 Negative_regulation of Positive_regulation of IFNA1 1 0.03 0.96 0.21
159 INT163096 Tlr2 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.16 0.21
160 INT254219 Binding of Myd88 and Tlr2 2 0.16 0.6 0.2
161 INT88022 Tnf Positive_regulation of Gene_expression of Faslg 1 0.26 0.76 0.2
162 INT348032 Fndc3b Positive_regulation of Tlr2 1 0.01 1.3 0.2
163 INT260436 Positive_regulation of Tlr9 Negative_regulation of Positive_regulation of Tlr7 1 0.14 0.65 0.2
164 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19
165 INT339503 Tlr2 Positive_regulation of Eif2ak2 1 0.12 0.09 0.19
166 INT123922 asa Positive_regulation of Tnf 1 0.04 1.96 0.19
167 INT329068 Tlr9 Positive_regulation of Localization of IFNA1 1 0.03 1.54 0.19
168 INT153461 Tnf Positive_regulation of Gene_expression of Ctgf 1 0.48 1.13 0.19
169 INT231763 Binding of HSPD1 and TLR2 1 0.12 2 0.19
170 INT66036 FOLR2 Negative_regulation of Tnf 1 0.00 0.56 0.18
171 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18
172 INT276946 Hspd1 Positive_regulation of Tlr2 2 0.37 1.01 0.17
173 INT61976 TBP Negative_regulation of Tnf 1 0.24 1.17 0.17
174 INT229245 Positive_regulation of Binding of FAS and Tnf 1 0.25 0.92 0.17
175 INT324820 Hsp90b1 Positive_regulation of Tlr2 1 0.16 0.42 0.17
176 INT229246 Binding of FAS and Tnf 1 0.19 0.91 0.17
177 INT146841 Tnf Positive_regulation of Trib3 1 0.03 0.77 0.16
178 INT221353 Tnf Positive_regulation of Gene_expression of RT1-CE1 1 0.05 0.39 0.16
179 INT350020 ARID1B Regulation of Positive_regulation of Tnf 1 0.04 1.78 0.16
180 INT316124 TLR2 Positive_regulation of Gene_expression of HLA-DRA 1 0.14 0.34 0.16
181 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16
182 INT146845 Tnf Positive_regulation of Positive_regulation of Trib3 1 0.03 0.77 0.16
183 INT204789 Binding of Tlr2 and Nod2 1 0.23 0.44 0.16
184 INT276958 Binding of Tlr2 and Clec7a 1 0.09 0.58 0.15
185 INT228216 Positive_regulation of Mapk14 Regulation of Gene_expression of Tlr2 1 0.09 1.11 0.15
186 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15
187 INT324874 Positive_regulation of Tlr2 Positive_regulation of Gene_expression of Mif 1 0.05 0.66 0.15
188 INT324860 Tlr2 Positive_regulation of Gene_expression of Mif 1 0.05 0.66 0.15
189 INT221352 Tnf Negative_regulation of Il1a 1 0.05 0.3 0.15
190 INT276948 Tlr2 Negative_regulation of Gene_expression of Tlr4 1 0.25 1.06 0.14
191 INT333270 Tlr2 Positive_regulation of Localization of Ccl20 1 0.24 0.16 0.14
192 INT139340 Il1b Positive_regulation of Positive_regulation of Tnf 1 0.09 1.26 0.14
193 INT348040 TNF Positive_regulation of Gene_expression of Tlr2 1 0.02 0.98 0.14
194 INT333271 Tlr9 Positive_regulation of Localization of Ccl20 1 0.24 0.16 0.14
195 INT146846 Tnf Negative_regulation of Plin1 1 0.59 0.66 0.13
196 INT276950 Hspd1 Positive_regulation of Positive_regulation of Tlr2 1 0.22 1.25 0.13
197 INT342520 HSP90B1 Positive_regulation of Gene_expression of TLR2 1 0.06 0.4 0.13
198 INT139342 Cts8 Regulation of Gene_expression of Tnf 1 0.06 0.96 0.13
199 INT345280 Binding of Tlr2 and Tlr7 1 0.05 0.49 0.12
200 INT230463 Binding of MT1JP and TLR2 1 0.02 0.44 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-18 production. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interleukin-18 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
2 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
3 INT10166 Localization of Tnf 237 0.81 153.95 88.64
4 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
5 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
6 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
7 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
8 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
9 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
10 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
11 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
12 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
13 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
14 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
15 INT10173 Binding of Tnf 45 0.48 35.6 14.32
16 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
17 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
18 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
19 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65
20 INT150540 Binding of TLR2 50 0.45 35.86 10.43
21 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05
22 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
23 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
24 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67
25 INT207892 Binding of Tlr9 35 0.46 26.66 6.61
26 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4
27 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43
28 INT174688 Binding of Tlr2 45 0.42 36.65 5.25
29 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18
30 INT185398 Negative_regulation of Gene_expression of TLR2 34 0.55 27.21 4.73
31 INT188672 Positive_regulation of Tlr9 15 0.67 13.1 4.48
32 INT149986 Positive_regulation of Gene_expression of Tlr9 5 0.67 8.18 4.15
33 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99
34 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
35 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
36 INT264970 Positive_regulation of Localization of TLR2 1 0.11 4.21 3.37
37 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
38 INT186805 Transcription of TLR2 12 0.63 9.66 3.04
39 INT260424 Negative_regulation of Tlr9 8 0.41 8.19 2.92
40 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
41 INT204524 Binding of TLR9 17 0.43 11.69 2.76
42 INT133029 Regulation of TLR2 18 0.56 11.31 2.62
43 INT186799 Localization of TLR2 5 0.68 2.51 2.58
44 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
45 INT204775 Regulation of Tlr2 21 0.41 13.6 2.18
46 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
47 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
48 INT228195 Negative_regulation of Gene_expression of Tlr2 14 0.40 12.17 1.74
49 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
50 INT175307 Regulation of Gene_expression of TLR2 9 0.56 7.08 1.58
51 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
52 INT204530 Positive_regulation of Gene_expression of TLR9 14 0.70 6.85 1.48
53 INT174683 Transcription of Tlr2 12 0.58 5.95 1.4
54 INT221131 Localization of Tlr2 17 0.80 13.82 1.28
55 INT151567 Gene_expression of Tlr9 6 0.72 3.63 1.26
56 INT146914 Negative_regulation of TLR2 12 0.53 7.41 1.23
57 INT190804 Positive_regulation of Tlr2 6 0.66 3.7 1.16
58 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
59 INT288493 Positive_regulation of Gene_expression of Tlr2 4 0.66 4.38 0.94
60 INT145760 Binding of Tlr2 5 0.46 3.59 0.89
61 INT188575 Positive_regulation of Transcription of TLR2 1 0.30 1.37 0.88
62 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
63 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
64 INT294787 Localization of TLR9 2 0.67 2.35 0.75
65 INT224630 Positive_regulation of Positive_regulation of Tlr2 6 0.46 4.14 0.73
66 INT228188 Regulation of Gene_expression of Tlr2 5 0.45 6.96 0.71
67 INT331594 Localization of Tlr9 1 0.41 1.66 0.71
68 INT331595 Positive_regulation of Localization of Tlr9 1 0.28 1.66 0.71
69 INT186801 Positive_regulation of Binding of TLR2 3 0.42 2.05 0.67
70 INT290394 Negative_regulation of Positive_regulation of TLR2 4 0.34 2.8 0.65
71 INT296782 Phosphorylation of Tlr9 1 0.61 0.53 0.63
72 INT180531 Positive_regulation of Positive_regulation of TLR2 4 0.32 4.28 0.62
73 INT234597 Negative_regulation of Positive_regulation of Tlr2 2 0.30 2.25 0.52
74 INT234587 Positive_regulation of Transcription of Tlr2 3 0.36 1.84 0.51
75 INT288490 Binding of Tlr9 1 0.25 1.88 0.51
76 INT188677 Positive_regulation of Positive_regulation of Tlr9 2 0.29 1.22 0.49
77 INT325457 Negative_regulation of Binding of TLR2 1 0.04 1.3 0.43
78 INT204533 Regulation of Gene_expression of TLR9 8 0.55 2.81 0.4
79 INT72086 Regulation of Regulation of Tnf 1 0.45 0.3 0.4
80 INT219171 Negative_regulation of Positive_regulation of TLR9 1 0.18 1.3 0.39
81 INT182134 Transcription of TLR9 2 0.72 1.21 0.37
82 INT284455 Regulation of Gene_expression of Tlr9 1 0.30 1.19 0.37
83 INT143535 Protein_catabolism of Tnf 2 0.86 3.43 0.33
84 INT329061 Positive_regulation of Tlr9 1 0.47 2.05 0.29
85 INT288189 Negative_regulation of Negative_regulation of Tlr2 1 0.26 0.43 0.28
86 INT331590 Negative_regulation of Binding of Tlr9 1 0.24 1.52 0.28
87 INT204528 Negative_regulation of Gene_expression of TLR9 5 0.52 4.47 0.27
88 INT236357 Negative_regulation of Positive_regulation of Tlr9 2 0.33 3.1 0.27
89 INT288186 Regulation of Binding of Tlr2 2 0.32 1.72 0.26
90 INT224614 Regulation of Positive_regulation of Tlr2 1 0.13 0.56 0.26
91 INT204531 Negative_regulation of TLR9 1 0.43 1.29 0.25
92 INT145758 Regulation of Tlr2 3 0.43 0.94 0.23
93 INT145761 Negative_regulation of Tlr2 2 0.41 1.97 0.23
94 INT294788 Regulation of Positive_regulation of TLR2 2 0.36 1.41 0.21
95 INT294633 Positive_regulation of Binding of Tlr2 1 0.44 0.42 0.16
96 INT350779 Positive_regulation of Positive_regulation of TLR9 1 0.08 0.8 0.15
97 INT145759 Regulation of Gene_expression of Tlr2 3 0.43 0.98 0.14
98 INT301958 Positive_regulation of Regulation of Tlr2 1 0.21 0.32 0.13
99 INT170142 Regulation of Protein_catabolism of Tnf 1 0.44 1.53 0.13
100 INT204527 Regulation of TLR9 7 0.40 2.88 0.12
101 INT151569 Transcription of Tlr9 3 0.69 0.75 0.11
102 INT151566 Positive_regulation of Transcription of Tlr9 2 0.47 0.67 0.11
103 INT329058 Positive_regulation of Transcription of Tlr2 1 0.48 0.62 0.11
104 INT329049 Transcription of Tlr2 1 0.68 0.62 0.11
105 INT294789 Negative_regulation of Transcription of TLR2 2 0.39 0.73 0.1
106 INT295324 Regulation of Binding of Tnf 2 0.44 1.11 0.09
107 INT280015 Positive_regulation of Binding of TLR9 1 0.12 1.11 0.09
108 INT255976 Regulation of Transcription of Tlr2 1 0.22 0.89 0.09
109 INT269821 Regulation of Localization of Tlr2 1 0.27 1.04 0.07
110 INT246930 Negative_regulation of Transcription of Tlr2 1 0.36 0.92 0.04
111 INT145757 Negative_regulation of Gene_expression of Tlr2 2 0.41 0.68 0.03
112 INT276939 Positive_regulation of Phosphorylation of Tlr2 1 0.46 0.6 0.03
113 INT204526 Positive_regulation of Transcription of TLR9 1 0.50 0.06 0.03
114 INT276931 Phosphorylation of Tlr2 1 0.75 0.6 0.03
115 INT246929 Positive_regulation of Localization of Tlr2 2 0.42 0.26 0
116 INT246927 Negative_regulation of Binding of Tlr2 1 0.31 0 0
117 INT294790 Regulation of Localization of TLR9 1 0.40 0 0
118 INT285438 Regulation of Regulation of TLR9 1 0.40 0 0
119 INT161253 Regulation of Gene_expression of Tlr9 1 0.09 0.18 0
120 INT324755 Positive_regulation of Binding of Tlr9 1 0.26 0.17 0
121 INT161254 Regulation of Tlr9 1 0.09 0.18 0
122 INT341500 Regulation of Binding of TLR2 1 0.12 0.25 0
123 INT294786 Regulation of Localization of TLR2 1 0.41 0 0
124 INT294781 Negative_regulation of Negative_regulation of TLR2 1 0.39 0.08 0
125 INT329056 Positive_regulation of Gene_expression of Tlr9 1 0.43 0.09 0
126 INT151568 Negative_regulation of Transcription of Tlr9 1 0.41 0.08 0
127 INT341498 Negative_regulation of Gene_expression of Tlr9 1 0.11 0.38 0
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