GO:0032754

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Name positive regulation of interleukin-5 production
Categary Process
Go Slim No
Go Link GO:0032754
Unique Molecular Interactions 99
Total Molecular Interactions 135
Total Single Events 875
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-5 production. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interleukin-5 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT325267 Il33 Positive_regulation of Gene_expression of Il4 1 0.16 1.59 0.69
2 INT325263 Il33 Positive_regulation of Gene_expression of Il5 1 0.16 1.59 0.69
3 INT325270 Il33 Positive_regulation of Gene_expression of Il6 1 0.20 1.59 0.69
4 INT54304 Il1rl1 Regulation of Regulation of Pdyn 1 0.04 0.23 0.54
5 INT164902 Binding of IL1RL1 and IL33 4 0.37 1.2 0.53
6 INT325259 Il33 Positive_regulation of Gene_expression of Spg21 1 0.07 1.23 0.53
7 INT325269 Il33 Positive_regulation of Spg21 1 0.05 1.11 0.48
8 INT164890 Binding of IL1RAP and IL33 1 0.09 0.2 0.36
9 INT164904 Binding of IL1A and IL33 1 0.39 0.19 0.35
10 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34
11 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
12 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33
13 INT325266 Positive_regulation of Spg21 Positive_regulation of Il33 1 0.05 0.75 0.32
14 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
15 INT325265 Il33 Positive_regulation of Gene_expression of Ik 1 0.01 0.67 0.32
16 INT226512 Il1rl1 Positive_regulation of Jun 1 0.12 0.34 0.29
17 INT226505 Il1rl1 Positive_regulation of Mapk8 1 0.04 0.4 0.29
18 INT226509 Il1rl1 Positive_regulation of Gene_expression of Mapk8 1 0.05 0.4 0.29
19 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
20 INT311046 Binding of CSF2 and IL33 1 0.00 1.86 0.26
21 INT272997 Binding of CYP3A4 and IL33 1 0.03 0 0.25
22 INT272998 IL33 Negative_regulation of CYP2D6 1 0.04 0 0.25
23 INT328621 Gene_expression of Il1rl1 Positive_regulation of Cfp 1 0.00 0.06 0.23
24 INT325276 Il33 Positive_regulation of Gene_expression of TNF 1 0.04 0.82 0.23
25 INT108842 RARA Positive_regulation of Gene_expression of GDF15 1 0.52 0.68 0.23
26 INT169567 IL33 Regulation of Pscs 1 0.03 0.46 0.19
27 INT164892 IL33 Regulation of Gene_expression of IL1RAP 1 0.06 0.2 0.18
28 INT63443 Binding of Pomc and Il1rl1 1 0.04 0.06 0.18
29 INT164908 Binding of IL1RAP and IL1RL1 1 0.08 0.1 0.18
30 INT319381 Binding of ST2 and IL33 1 0.13 1.01 0.18
31 INT355566 IL1RL1 Positive_regulation of Gene_expression of NOS2 1 0.00 0.27 0.17
32 INT313023 Binding of Rara and Rxra 1 0.06 0.73 0.17
33 INT302381 Il33 Regulation of Gene_expression of Il4 1 0.01 0.76 0.16
34 INT226527 Il1rl1 Positive_regulation of Gene_expression of IK 1 0.00 0.42 0.15
35 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
36 INT226507 Il1rl1 Positive_regulation of Gene_expression of Jun 1 0.13 0.2 0.15
37 INT226518 Il1rl1 Positive_regulation of MAPK14 1 0.04 0.2 0.15
38 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
39 INT305371 Binding of IL1RL1 and MRI1 1 0.09 0.95 0.15
40 INT304169 Il33 Positive_regulation of Gene_expression of Itgam 1 0.02 1.18 0.15
41 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
42 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
43 INT226520 Il1rl1 Positive_regulation of Gene_expression of MAPK14 1 0.03 0.2 0.15
44 INT226516 Il1rl1 Positive_regulation of Phosphorylation of Jun 1 0.02 0.19 0.14
45 INT192106 Regulation of Binding of Rara and Retsat 1 0.00 0.83 0.13
46 INT169562 PDGFD Positive_regulation of Gene_expression of IL33 1 0.03 0.35 0.13
47 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
48 INT192105 Binding of Rara and Retsat 1 0.00 0.83 0.13
49 INT325272 Il1rl1 Positive_regulation of Gene_expression of TNF 1 0.02 0.41 0.12
50 INT325268 Il1rl1 Positive_regulation of Gene_expression of Spg21 1 0.05 0.41 0.12
51 INT192104 Binding of Rara and Rxrg 1 0.00 0.82 0.1
52 INT25285 CBS Negative_regulation of Localization of IL1RL1 1 0.05 0 0.09
53 INT226515 Binding of Il1rl1 and Il33 1 0.02 0.36 0.08
54 INT201380 RARA Positive_regulation of Regulation of CPOX 1 0.07 0.21 0.08
55 INT303997 IL1RL1 Positive_regulation of Lep 1 0.01 0.2 0.07
56 INT197727 Binding of RARA and Positive_regulation of PPARA 1 0.02 0.96 0.05
57 INT325256 Chchd8 Regulation of Il1rl1 1 0.00 0.33 0.05
58 INT325255 Chchd8 Regulation of Il33 1 0.00 0.33 0.05
59 INT325261 Ralbp1 Positive_regulation of Gene_expression of Il33 1 0.01 0 0.05
60 INT291714 Binding of RARA and Rxra 3 0.07 0.2 0.03
61 INT182924 Binding of RARA and NR1H4 3 0.02 1.9 0
62 INT182918 Binding of DR1 and RARA 2 0.08 0 0
63 INT182949 Binding of RARA and VDR 1 0.20 0 0
64 INT164899 IL33 Positive_regulation of IFNG 1 0.25 0.05 0
65 INT285996 Binding of ACAT1 and IL1RL1 1 0.00 0 0
66 INT164907 IFNG Positive_regulation of Gene_expression of IL1RL1 1 0.31 0.11 0
67 INT204927 Binding of LGMN and IL33 1 0.00 0.52 0
68 INT164895 IL33 Positive_regulation of Gene_expression of CCL2 1 0.16 0.05 0
69 INT164901 IL33 Positive_regulation of Gene_expression of CXCL10 1 0.16 0.05 0
70 INT164906 IL33 Positive_regulation of Gene_expression of IL4 1 0.43 0.05 0
71 INT164910 IL33 Positive_regulation of Gene_expression of CXCL1 1 0.12 0.05 0
72 INT164900 STAT6 Positive_regulation of Gene_expression of IL1RL1 1 0.42 0.06 0
73 INT182919 TGFBI Regulation of RARA 1 0.29 0.08 0
74 INT276606 Binding of DBT and IL33 1 0.01 0 0
75 INT164891 STAT1 Positive_regulation of Gene_expression of IL1RL1 1 0.41 0.06 0
76 INT342366 Binding of Rara and OSBPL1A 1 0.16 0 0
77 INT182961 Binding of RARA and KCNIP3 1 0.21 0.76 0
78 INT164911 Binding of IL1RL1 and ITS 1 0.48 0 0
79 INT291682 Positive_regulation of Binding of RARA and TNFRSF10B 1 0.03 0 0
80 INT164897 IL4 Positive_regulation of Gene_expression of IL1RL1 1 0.54 0.06 0
81 INT291683 Binding of RARA and TNFRSF10B 1 0.03 0 0
82 INT234440 Binding of PROC and RARA 1 0.00 0.73 0
83 INT325271 Positive_regulation of Il33 Regulation of Gene_expression of Il1rl1 1 0.22 0 0
84 INT164912 IL33 Positive_regulation of Gene_expression of IL8 1 0.45 0.05 0
85 INT164903 IL33 Positive_regulation of Gene_expression of CXCL2 1 0.12 0.05 0
86 INT164889 IL33 Positive_regulation of Gene_expression of IFNG 1 0.25 0.05 0
87 INT164909 IL33 Positive_regulation of Phosphorylation of NFKBIA 1 0.53 0.05 0
88 INT342362 Binding of Irs1 and Rara 1 0.15 0 0
89 INT276608 Binding of UBE2S and IL33 1 0.00 0.32 0
90 INT225504 Binding of gr and Rara 1 0.02 0 0
91 INT182948 KCNIP3 Regulation of Transcription of RARA 1 0.23 0.55 0
92 INT291681 Positive_regulation of Binding of DR1 and RARA 1 0.06 0 0
93 INT164893 IL33 Positive_regulation of Gene_expression of IL6 1 0.46 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-5 production. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interleukin-5 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11854 Gene_expression of Il1rl1 57 0.77 30.19 38.25
2 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
3 INT11855 Positive_regulation of Gene_expression of Il1rl1 19 0.69 12.22 14.57
4 INT65638 Negative_regulation of Gene_expression of Il1rl1 12 0.58 7.86 11.7
5 INT226402 Gene_expression of Il33 60 0.77 23.82 8.67
6 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
7 INT87432 Regulation of Gene_expression of Il1rl1 6 0.58 4.5 6.62
8 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28
9 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
10 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2
11 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
12 INT15299 Gene_expression of IL1RL1 37 0.69 10.09 3.43
13 INT164920 Gene_expression of IL33 22 0.76 13.63 3.16
14 INT45014 Regulation of IL1RL1 12 0.14 1.87 2.67
15 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
16 INT52601 Positive_regulation of Il1rl1 12 0.66 1.34 2.22
17 INT325254 Positive_regulation of Il33 19 0.69 6.56 2.09
18 INT25286 Localization of IL1RL1 7 0.56 3.17 2.07
19 INT325244 Localization of Il33 1 0.80 4.17 1.8
20 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
21 INT116022 Positive_regulation of Positive_regulation of RARA 3 0.11 0.94 1.68
22 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
23 INT28681 Gene_expression of Il1rl1 4 0.55 3.04 1.46
24 INT67457 Binding of Rara 12 0.24 8.28 1.45
25 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
26 INT116008 Binding of Gata3 2 0.34 1.37 1.41
27 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
28 INT81400 Binding of RARA 25 0.36 12.93 1.27
29 INT182985 Transcription of RARA 9 0.60 3.52 1.12
30 INT28493 Positive_regulation of IL1RL1 10 0.47 3.44 1.11
31 INT69758 Negative_regulation of Positive_regulation of Rara 2 0.32 0.24 0.97
32 INT192090 Localization of Rara 6 0.46 4.15 0.89
33 INT48251 Regulation of Positive_regulation of Rara 2 0.33 0 0.88
34 INT7552 Negative_regulation of IL1RL1 12 0.42 1.68 0.87
35 INT63442 Localization of Il1rl1 2 0.12 0.05 0.87
36 INT120366 Negative_regulation of Rara 2 0.35 0.15 0.86
37 INT48250 Regulation of Rara 3 0.29 2.47 0.83
38 INT48249 Positive_regulation of Positive_regulation of Rara 2 0.26 0 0.83
39 INT325230 Positive_regulation of Gene_expression of Il33 1 0.50 1.47 0.83
40 INT212109 Localization of RARA 5 0.65 3.17 0.79
41 INT112386 Positive_regulation of Gene_expression of IL1RL1 4 0.47 2.72 0.77
42 INT28682 Negative_regulation of Gene_expression of Il1rl1 2 0.42 0.31 0.75
43 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
44 INT204929 Binding of IL33 18 0.08 4.74 0.7
45 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
46 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
47 INT226421 Regulation of Il33 2 0.45 2.7 0.68
48 INT91398 Regulation of RARA 7 0.59 5.84 0.67
49 INT164916 Binding of IL1RL1 9 0.33 1.84 0.66
50 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
51 INT226403 Regulation of Gene_expression of Il33 2 0.61 1.94 0.63
52 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
53 INT234472 Positive_regulation of Transcription of RARA 2 0.44 0.13 0.58
54 INT273000 Localization of IL33 5 0.45 1.77 0.56
55 INT82749 Negative_regulation of Gene_expression of IL1RL1 4 0.40 2 0.52
56 INT201392 Negative_regulation of RARA 8 0.30 2.99 0.5
57 INT273003 Positive_regulation of IL33 4 0.26 3.27 0.49
58 INT325251 Positive_regulation of Localization of Il33 1 0.69 1.03 0.45
59 INT182966 Regulation of Gene_expression of RARA 2 0.39 0.12 0.42
60 INT211982 Negative_regulation of Binding of Rara 1 0.28 0.24 0.42
61 INT325250 Regulation of Positive_regulation of Il33 2 0.45 1.16 0.39
62 INT273005 Negative_regulation of IL33 4 0.07 2.4 0.38
63 INT80742 Regulation of Il1rl1 1 0.08 0.09 0.37
64 INT325234 Negative_regulation of Il33 1 0.43 0.67 0.37
65 INT164919 Transcription of IL1RL1 2 0.64 2.74 0.35
66 INT325231 Negative_regulation of Negative_regulation of Il33 1 0.43 0.67 0.34
67 INT226389 Localization of Il1rl1 2 0.53 0.93 0.31
68 INT319433 Positive_regulation of Localization of IL1RL1 1 0.35 1.39 0.26
69 INT226397 Positive_regulation of Il1rl1 2 0.31 1.04 0.25
70 INT10375 Negative_regulation of Gene_expression of RARA 1 0.57 0.97 0.22
71 INT325238 Negative_regulation of Il1rl1 1 0.27 0.55 0.17
72 INT325246 Regulation of Localization of Il33 1 0.27 0.23 0.16
73 INT325252 Positive_regulation of Gene_expression of Il1rl1 1 0.36 0.43 0.15
74 INT319410 Positive_regulation of Transcription of IL1RL1 1 0.48 1.49 0.14
75 INT169566 Positive_regulation of Gene_expression of IL33 1 0.41 0.38 0.14
76 INT192091 Regulation of Localization of Rara 1 0.04 0.67 0.13
77 INT325249 Binding of Il33 1 0.37 0.72 0.13
78 INT319432 Positive_regulation of Localization of IL33 1 0.26 1.02 0.13
79 INT116052 Phosphorylation of Il1rl1 1 0.05 0.1 0.13
80 INT164918 Regulation of Gene_expression of IL33 2 0.44 1.09 0.12
81 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
82 INT169564 Negative_regulation of Gene_expression of IL33 1 0.38 0.3 0.11
83 INT25287 Negative_regulation of Localization of IL1RL1 1 0.04 0 0.09
84 INT214071 Negative_regulation of Transcription of RARA 3 0.37 1.77 0.07
85 INT182975 Phosphorylation of RARA 2 0.58 0.23 0.07
86 INT72901 Negative_regulation of Il1rl1 2 0.27 0.59 0.06
87 INT211317 Positive_regulation of Positive_regulation of IL1RL1 1 0.25 0.09 0.04
88 INT325253 Negative_regulation of Positive_regulation of Il33 1 0.42 0 0.03
89 INT325247 Negative_regulation of Gene_expression of Il33 1 0.42 0 0.03
90 INT182990 Positive_regulation of Gene_expression of RARA 5 0.40 3.45 0
91 INT182965 Positive_regulation of Phosphorylation of RARA 1 0.29 0 0
92 INT325237 Transcription of Il33 1 0.68 0.15 0
93 INT325243 Regulation of Gene_expression of Il1rl1 1 0.44 0 0
94 INT335229 Regulation of Transcription of RARA 1 0.15 0.95 0
95 INT183002 Positive_regulation of Binding of RARA 1 0.29 1.08 0
96 INT276617 Negative_regulation of Localization of IL33 1 0.03 0.28 0
97 INT286002 Negative_regulation of Binding of IL1RL1 1 0.02 0 0
98 INT335226 Negative_regulation of Negative_regulation of RARA 1 0.24 0.71 0
99 INT193363 Regulation of Binding of IL1RL1 1 0.02 0 0
100 INT325235 Transcription of Il1rl1 1 0.49 0.15 0
101 INT325245 Positive_regulation of Localization of Il1rl1 1 0.31 0 0
102 INT164914 Regulation of Gene_expression of IL1RL1 1 0.40 0.09 0
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