GO:0032755

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Name positive regulation of interleukin-6 production
Categary Process
Go Slim No
Go Link GO:0032755
Unique Molecular Interactions 5201
Total Molecular Interactions 7678
Total Single Events 52953
Pain Genes Associated 71

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-6 production. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interleukin-6 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
3 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
4 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
5 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
6 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
7 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
8 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
9 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
10 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
11 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
12 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
13 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
14 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
15 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
16 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
17 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
18 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
19 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
20 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
21 INT91649 Binding of Lbp and SPECC1 1 0.12 2.88 2.78
22 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
23 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
24 INT212505 Binding of pr and Lbp 1 0.01 4.26 2.62
25 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
26 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
27 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
28 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
29 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
30 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
31 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
32 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
33 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
34 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
35 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
36 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
37 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
38 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
39 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
40 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
41 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
42 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
43 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
44 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
45 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
46 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
47 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
48 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
49 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
50 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
51 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
52 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
53 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
54 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
55 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
56 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
57 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
58 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
59 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
60 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
61 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
62 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
63 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
64 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
65 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
66 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
67 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
68 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
69 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
70 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
71 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
72 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
73 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
74 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
75 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
76 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
77 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
78 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
79 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
80 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
81 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
82 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
83 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
84 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
85 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
86 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
87 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
88 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
89 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
90 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
91 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
92 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
93 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
94 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
95 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
96 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
97 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
98 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
99 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
100 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
101 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
102 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
103 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
104 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
105 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
106 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
107 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
108 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
109 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
110 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
111 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
112 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
113 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
114 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
115 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
116 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
117 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
118 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
119 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
120 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
121 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
122 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
123 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
124 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
125 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
126 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
127 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
128 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
129 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
130 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
131 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
132 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
133 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
134 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
135 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
136 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
137 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
138 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
139 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
140 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
141 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
142 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
143 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
144 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
145 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
146 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
147 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
148 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
149 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
150 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
151 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
152 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
153 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
154 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
155 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
156 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
157 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
158 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
159 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
160 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
161 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
162 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
163 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
164 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
165 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
166 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
167 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
168 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
169 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
170 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
171 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
172 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
173 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
174 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
175 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
176 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
177 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
178 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
179 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
180 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
181 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
182 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
183 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
184 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
185 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
186 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
187 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
188 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
189 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1
190 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
191 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
192 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
193 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
194 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
195 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
196 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
197 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
198 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
199 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
200 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-6 production. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interleukin-6 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
5 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
6 INT6852 Localization of TNF 883 0.81 705.95 270.84
7 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
8 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
9 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
10 INT6481 Binding of TNF 624 0.48 510.2 214.82
11 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
12 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
13 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
14 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
15 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
16 INT9660 Regulation of TNF 363 0.62 312.94 139.99
17 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
18 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
19 INT1026 Binding of Lbp 207 0.48 150.96 119.16
20 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
21 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
22 INT12082 Localization of IL6 365 0.81 241.78 105.78
23 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
24 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
25 INT10166 Localization of Tnf 237 0.81 153.95 88.64
26 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
27 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
28 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
29 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
30 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
31 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
32 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
33 INT6849 Localization of IL1B 229 0.81 112.56 69.63
34 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
35 INT19511 Localization of Il6 212 0.81 118.17 67.67
36 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
37 INT11937 Localization of Il6 228 0.81 139.83 64.39
38 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
39 INT9664 Binding of LBP 127 0.48 94.9 63.42
40 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
41 INT10706 Regulation of Il6 150 0.62 93.23 62.34
42 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
43 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
44 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
45 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16
46 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
47 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
48 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
49 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
50 INT9210 Regulation of IL6 166 0.62 125.61 49.95
51 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
52 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
53 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05
54 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
55 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
56 INT13354 Transcription of TNF 108 0.72 85.81 42.32
57 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
58 INT9372 Negative_regulation of Lbp 86 0.58 46.54 41.71
59 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
60 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
61 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
62 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
63 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
64 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
65 INT6484 Binding of IL1B 122 0.47 75.84 35.07
66 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
67 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
68 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
69 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23
70 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
71 INT9655 Regulation of Il6 98 0.62 70.92 31.95
72 INT35406 Localization of Tnf 94 0.81 64.63 31.65
73 INT9347 Localization of Il1b 58 0.81 26.13 31.53
74 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
75 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
76 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
77 INT86437 Binding of IL6 154 0.48 121.22 29.3
78 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
79 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
80 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73
81 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
82 INT5966 Localization of Il1a 50 0.78 22.91 26.54
83 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
84 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89
85 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
86 INT1030 Localization of Lbp 52 0.74 38.92 24.91
87 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
88 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
89 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
90 INT134651 Binding of TLR4 89 0.48 66.96 23.19
91 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
92 INT48081 Localization of Il1b 46 0.80 21.59 22.4
93 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
94 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
95 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
96 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
97 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
98 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
99 INT51474 Binding of Il6 55 0.48 44.99 20.52
100 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
101 INT49985 Transcription of Il6 62 0.72 40.13 20.29
102 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
103 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
104 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
105 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
106 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
107 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
108 INT52179 Regulation of Lbp 39 0.61 25.4 18.32
109 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
110 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
111 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16
112 INT61626 Transcription of IL6 73 0.72 42.04 17.86
113 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
114 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
115 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
116 INT125947 Gene_expression of Adora2b 57 0.75 23.69 17
117 INT54077 Gene_expression of Adcyap1 62 0.78 23.17 16.75
118 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
119 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
120 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
121 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
122 INT216751 Gene_expression of ADORA2B 36 0.60 3.42 15.6
123 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
124 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
125 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
126 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
127 INT58896 Localization of Adcyap1 35 0.81 4.57 14.77
128 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
129 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
130 INT48259 Positive_regulation of Adcyap1 33 0.67 10.94 14.39
131 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
132 INT10173 Binding of Tnf 45 0.48 35.6 14.32
133 INT194850 Positive_regulation of Adora2b 43 0.61 20.57 13.89
134 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
135 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
136 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
137 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
138 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
139 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
140 INT142621 Positive_regulation of Gene_expression of CD36 38 0.70 15.18 13.4
141 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
142 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14
143 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
144 INT54763 Binding of Il6 82 0.48 63.27 12.89
145 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
146 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
147 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
148 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
149 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35
150 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
151 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
152 INT50933 Transcription of Il6 38 0.72 24.31 11.58
153 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58
154 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
155 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
156 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
157 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65
158 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
159 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59
160 INT87393 Gene_expression of Ccr5 19 0.65 11 10.51
161 INT150540 Binding of TLR2 50 0.45 35.86 10.43
162 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
163 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
164 INT57000 Localization of LBP 21 0.78 11.01 10.01
165 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
166 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
167 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
168 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
169 INT106199 Positive_regulation of Adcyap1 32 0.68 13.68 9.14
170 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05
171 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
172 INT15768 Gene_expression of Il1a 20 0.71 9.31 8.78
173 INT32624 Regulation of LBP 15 0.60 11.48 8.71
174 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
175 INT226402 Gene_expression of Il33 60 0.77 23.82 8.67
176 INT73234 Positive_regulation of Lbp 13 0.69 12.55 8.57
177 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
178 INT209866 Regulation of Gene_expression of CD36 27 0.60 10.04 8.42
179 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
180 INT52116 Regulation of Adcyap1 20 0.53 6.1 8.14
181 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
182 INT66926 Transcription of Il1b 15 0.69 13.16 7.81
183 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76
184 INT48077 Positive_regulation of Localization of Il1b 17 0.69 8.8 7.68
185 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
186 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
187 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57
188 INT65964 Regulation of Adcyap1 13 0.45 10.1 7.54
189 INT68299 Binding of Tnf 17 0.39 12.55 7.49
190 INT38503 Positive_regulation of Ripk2 11 0.67 2.9 7.47
191 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
192 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
193 INT216752 Binding of ADORA2B 17 0.36 0.76 7.36
194 INT5308 Regulation of Il1a 17 0.44 10.8 7.31
195 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
196 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
197 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
198 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02
199 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
200 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
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