GO:0032757

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Name positive regulation of interleukin-8 production
Categary Process
Go Slim No
Go Link GO:0032757
Unique Molecular Interactions 1878
Total Molecular Interactions 2878
Total Single Events 24683
Pain Genes Associated 43

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-8 production. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interleukin-8 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
5 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
6 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
7 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
8 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
9 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
10 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
11 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
12 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
13 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
14 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
15 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
16 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
17 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
18 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
19 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
20 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
21 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
22 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
23 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
24 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
25 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
26 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
27 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
28 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
29 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
30 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
31 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
32 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
33 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
34 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
35 INT91649 Binding of Lbp and SPECC1 1 0.12 2.88 2.78
36 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
37 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
38 INT212505 Binding of pr and Lbp 1 0.01 4.26 2.62
39 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
40 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
41 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
42 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
43 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
44 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
45 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
46 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
47 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
48 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
49 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
50 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
51 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
52 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
53 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
54 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
55 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
56 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
57 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
58 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
59 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
60 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
61 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
62 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
63 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
64 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
65 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
66 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
67 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
68 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
69 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
70 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
71 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
72 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
73 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
74 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71
75 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
76 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
77 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
78 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
79 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
80 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
81 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
82 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
83 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
84 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
85 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
86 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
87 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
88 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
89 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
90 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
91 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
92 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
93 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
94 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
95 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
96 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
97 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
98 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
99 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
100 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
101 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
102 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
103 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
104 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
105 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
106 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
107 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
108 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
109 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
110 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
111 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
112 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
113 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
114 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
115 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
116 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
117 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
118 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
119 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
120 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
121 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
122 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
123 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
124 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
125 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
126 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
127 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
128 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
129 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
130 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
131 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
132 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
133 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
134 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
135 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
136 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
137 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
138 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
139 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
140 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
141 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
142 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
143 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
144 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
145 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
146 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
147 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
148 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
149 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
150 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
151 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
152 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
153 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
154 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
155 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
156 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
157 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
158 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
159 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
160 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
161 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
162 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
163 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
164 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
165 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
166 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
167 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
168 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
169 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
170 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
171 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
172 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
173 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
174 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
175 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
176 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
177 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
178 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
179 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
180 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
181 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
182 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
183 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
184 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
185 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
186 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
187 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
188 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
189 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
190 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
191 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
192 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
193 INT70495 CALCA Positive_regulation of CALCB 2 0.40 0 1.08
194 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
195 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
196 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
197 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
198 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
199 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
200 INT79372 Calca Regulation of Pnoc 1 0.34 0 1.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-8 production. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interleukin-8 production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
8 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
9 INT626 Localization of CALCA 289 0.81 125.39 221.15
10 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
11 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
12 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
13 INT2541 Binding of Calca 200 0.48 67.14 134.62
14 INT5008 Localization of Calca 204 0.81 80.35 125.16
15 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
16 INT1026 Binding of Lbp 207 0.48 150.96 119.16
17 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
18 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
19 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
20 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
21 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
22 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
23 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
24 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
25 INT6849 Localization of IL1B 229 0.81 112.56 69.63
26 INT9664 Binding of LBP 127 0.48 94.9 63.42
27 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
28 INT6761 Binding of CALCA 100 0.48 26.71 62.05
29 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
30 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
31 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
32 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16
33 INT4891 Transcription of Calca 81 0.72 35.27 53.75
34 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
35 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
36 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
37 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
38 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05
39 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
40 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
41 INT9372 Negative_regulation of Lbp 86 0.58 46.54 41.71
42 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
43 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
44 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
45 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95
46 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
47 INT6484 Binding of IL1B 122 0.47 75.84 35.07
48 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
49 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
50 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
51 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23
52 INT9347 Localization of Il1b 58 0.81 26.13 31.53
53 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
54 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
55 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
56 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
57 INT22499 Regulation of Calca 42 0.62 17.32 28.02
58 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97
59 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73
60 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
61 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
62 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89
63 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
64 INT1030 Localization of Lbp 52 0.74 38.92 24.91
65 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
66 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
67 INT134651 Binding of TLR4 89 0.48 66.96 23.19
68 INT48081 Localization of Il1b 46 0.80 21.59 22.4
69 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
70 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
71 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
72 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
73 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
74 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
75 INT52179 Regulation of Lbp 39 0.61 25.4 18.32
76 INT104550 Positive_regulation of Il18 67 0.70 55.14 17.48
77 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
78 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
79 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
80 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
81 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
82 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
83 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8
84 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
85 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
86 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
87 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
88 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
89 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67
90 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
91 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
92 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4
93 INT141014 Positive_regulation of Gene_expression of Il18 46 0.68 47.63 13.3
94 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
95 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
96 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
97 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61
98 INT26217 Binding of Calca 22 0.48 5.22 12.57
99 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
100 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
101 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
102 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
103 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
104 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
105 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
106 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
107 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
108 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65
109 INT150540 Binding of TLR2 50 0.45 35.86 10.43
110 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
111 INT57000 Localization of LBP 21 0.78 11.01 10.01
112 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9
113 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53
114 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
115 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05
116 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
117 INT32624 Regulation of LBP 15 0.60 11.48 8.71
118 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
119 INT73234 Positive_regulation of Lbp 13 0.69 12.55 8.57
120 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
121 INT66926 Transcription of Il1b 15 0.69 13.16 7.81
122 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72
123 INT48077 Positive_regulation of Localization of Il1b 17 0.69 8.8 7.68
124 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
125 INT94127 Positive_regulation of Il18 14 0.69 14 7.47
126 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
127 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
128 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
129 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
130 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
131 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
132 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
133 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
134 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67
135 INT207892 Binding of Tlr9 35 0.46 26.66 6.61
136 INT48076 Negative_regulation of Localization of Il1b 10 0.59 3.46 6.58
137 INT91721 Binding of IL18 21 0.48 21.17 6.56
138 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
139 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
140 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4
141 INT84716 Negative_regulation of Positive_regulation of Il1b 9 0.57 5.34 6.27
142 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
143 INT183910 Negative_regulation of Gene_expression of Lbp 10 0.35 9.78 6.15
144 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
145 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12
146 INT104547 Negative_regulation of Il18 24 0.59 17.89 6.01
147 INT97797 Localization of TLR4 18 0.77 13.78 6
148 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
149 INT80750 Binding of Il1b 11 0.47 7.97 5.95
150 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89
151 INT86982 Transcription of Calca 9 0.69 2.98 5.74
152 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
153 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61
154 INT124705 Binding of Il18 29 0.47 19.02 5.59
155 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
156 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53
157 INT10705 Binding of Il1b 9 0.36 2.8 5.53
158 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
159 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43
160 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
161 INT5778 Regulation of Transcription of Calca 4 0.45 2.47 5.37
162 INT174688 Binding of Tlr2 45 0.42 36.65 5.25
163 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
164 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2
165 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18
166 INT1029 Positive_regulation of Gene_expression of Lbp 17 0.50 11.03 5.18
167 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
168 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08
169 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
170 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98
171 INT15941 Negative_regulation of Serpine1 42 0.58 21.07 4.95
172 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89
173 INT185398 Negative_regulation of Gene_expression of TLR2 34 0.55 27.21 4.73
174 INT52251 Negative_regulation of Binding of CALCA 3 0.41 0.57 4.71
175 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
176 INT104549 Localization of Il18 16 0.78 13.01 4.64
177 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59
178 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54
179 INT11106 Gene_expression of Lbp 10 0.67 10.29 4.52
180 INT188672 Positive_regulation of Tlr9 15 0.67 13.1 4.48
181 INT11354 Regulation of Gene_expression of SERPINE1 11 0.61 8.66 4.42
182 INT165891 Transcription of Il18 5 0.69 7.63 4.37
183 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
184 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26
185 INT11634 Regulation of SERPINE1 24 0.62 20.06 4.26
186 INT48080 Positive_regulation of Positive_regulation of Il1b 5 0.50 4.3 4.19
187 INT149986 Positive_regulation of Gene_expression of Tlr9 5 0.67 8.18 4.15
188 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12
189 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07
190 INT133602 Positive_regulation of Fadd 2 0.54 0.38 4.02
191 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99
192 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93
193 INT24677 Regulation of Negative_regulation of Calca 6 0.44 0.73 3.9
194 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
195 INT35175 Localization of IL18 18 0.80 12.96 3.83
196 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
197 INT141015 Regulation of Il18 14 0.59 6.3 3.73
198 INT158596 Binding of Tlr3 24 0.47 11.66 3.69
199 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
200 INT133733 Positive_regulation of Localization of Lbp 6 0.43 9.19 3.61
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