GO:0032760

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Name positive regulation of tumor necrosis factor production
Categary Process
Go Slim No
Go Link GO:0032760
Unique Molecular Interactions 2097
Total Molecular Interactions 3112
Total Single Events 18377
Pain Genes Associated 72

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of tumor necrosis factor production. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of tumor necrosis factor production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
5 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
6 INT91649 Binding of Lbp and SPECC1 1 0.12 2.88 2.78
7 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
8 INT212505 Binding of pr and Lbp 1 0.01 4.26 2.62
9 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
10 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
11 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
12 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
13 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
14 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
15 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
16 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
17 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
18 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
19 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
20 INT149491 PNOC Negative_regulation of Gene_expression of CD14 1 0.40 0.37 1.76
21 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71
22 INT158302 Il23a Regulation of Gene_expression of Il17a 1 0.06 1.45 1.7
23 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
24 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
25 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
26 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
27 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
28 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
29 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
30 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
31 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
32 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
33 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
34 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
35 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
36 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
37 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
38 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
39 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
40 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
41 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
42 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
43 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
44 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26
45 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
46 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
47 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24
48 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
49 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
50 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
51 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
52 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
53 INT227324 Binding of fd and Cd14 1 0.01 2.8 1.13
54 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
55 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
56 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
57 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
58 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
59 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
60 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04
61 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
62 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
63 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
64 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
65 INT203178 IL18 Positive_regulation of Gene_expression of Lts1 1 0.01 1.98 1.02
66 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
67 INT174910 Binding of LBP and IFIH1 1 0.04 1.01 1.01
68 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
69 INT317584 Binding of Lbp and Pgp 1 0.24 1.08 0.99
70 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
71 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
72 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
73 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
74 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97
75 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97
76 INT133617 Fas Positive_regulation of Fadd 1 0.48 0.07 0.96
77 INT275097 Twist1 Regulation of Ltp 1 0.01 0.37 0.96
78 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
79 INT142709 Binding of TWIST1 and CEBPZ 2 0.17 1.16 0.95
80 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
81 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93
82 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
83 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
84 INT227325 Binding of IRF6 and Cd14 1 0.01 2.51 0.93
85 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
86 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
87 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92
88 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
89 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
90 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
91 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9
92 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89
93 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
94 INT116771 Binding of MAVS and MRGPRX1 1 0.00 0.51 0.89
95 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
96 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
97 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
98 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
99 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87
100 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
101 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86
102 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86
103 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
104 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
105 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
106 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83
107 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
108 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
109 INT289658 Tnfrsf1a Positive_regulation of Mcpt1 1 0.02 0.76 0.81
110 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79
111 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79
112 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
113 INT296787 Tbrs1 Positive_regulation of Gene_expression of Tlr9 1 0.06 1.37 0.78
114 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
115 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
116 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
117 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
118 INT296788 Tlr9 Regulation of Positive_regulation of Il1 1 0.07 1.37 0.77
119 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
120 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
121 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
122 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
123 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
124 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
125 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
126 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
127 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
128 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72
129 INT317585 Binding of Lbp and Ppap2b 1 0.03 0.78 0.72
130 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
131 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72
132 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
133 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72
134 INT146460 IFNG Positive_regulation of Gene_expression of TNFRSF10D 1 0.03 1.46 0.72
135 INT275285 Ros1 Positive_regulation of Tnfrsf1a 1 0.27 1.06 0.72
136 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
137 INT151679 Ifng Negative_regulation of Oas1b 1 0.12 1.24 0.71
138 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
139 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
140 INT151676 Ifng Negative_regulation of Art2a-ps 1 0.00 1.25 0.71
141 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
142 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
143 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7
144 INT116020 Positive_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
145 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
146 INT116021 Binding of Il4 and Mavs 1 0.02 0.08 0.7
147 INT116019 Negative_regulation of Binding of Il4 and Mavs 1 0.02 0.08 0.7
148 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
149 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
150 INT120019 IL8 Positive_regulation of CCL3 1 0.02 0.99 0.7
151 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
152 INT282665 Binding of Gfap and Ticam1 1 0.01 0 0.69
153 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
154 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
155 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67
156 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
157 INT316690 Binding of Myd88 and Il1 2 0.06 1.75 0.66
158 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
159 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
160 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
161 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65
162 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
163 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
164 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
165 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
166 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64
167 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64
168 INT171976 Il18 Positive_regulation of Gene_expression of IFNA1 1 0.01 1.37 0.64
169 INT288202 Negative_regulation of Cd14 Positive_regulation of Positive_regulation of Mapk14 1 0.09 1.08 0.64
170 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63
171 INT56235 Ifng Positive_regulation of Gene_expression of RT1-EC2 1 0.23 0.33 0.62
172 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
173 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61
174 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
175 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
176 INT154533 Ifng Negative_regulation of Il4 1 0.11 0.62 0.6
177 INT154531 Ifng Negative_regulation of Il10 1 0.30 0.61 0.6
178 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
179 INT306320 Binding of Cd14 and Ly96 1 0.10 0.65 0.59
180 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
181 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
182 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
183 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59
184 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58
185 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
186 INT299004 Binding of Il18 and Il1 1 0.04 1.16 0.58
187 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
188 INT283980 Binding of IL12A and IL23A 2 0.24 1.33 0.57
189 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
190 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
191 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
192 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57
193 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57
194 INT139189 Binding of Daxx and Fadd 1 0.03 0.27 0.57
195 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
196 INT176370 IL18BP Negative_regulation of IL18 1 0.15 0.76 0.56
197 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
198 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56
199 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
200 INT96089 Binding of F2 and Pf4 1 0.00 1.31 0.56

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of tumor necrosis factor production. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of tumor necrosis factor production. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
2 INT1026 Binding of Lbp 207 0.48 150.96 119.16
3 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
4 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
5 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
6 INT9664 Binding of LBP 127 0.48 94.9 63.42
7 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
8 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
9 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16
10 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05
11 INT9372 Negative_regulation of Lbp 86 0.58 46.54 41.71
12 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95
13 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
14 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
15 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
16 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23
17 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13
18 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
19 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
20 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73
21 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
22 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2
23 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15
24 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
25 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89
26 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
27 INT1030 Localization of Lbp 52 0.74 38.92 24.91
28 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
29 INT8518 Localization of Ifng 53 0.81 36.68 24.13
30 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03
31 INT134651 Binding of TLR4 89 0.48 66.96 23.19
32 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09
33 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
34 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54
35 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
36 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
37 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
38 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
39 INT19509 Localization of Ifng 55 0.78 28.25 18.67
40 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
41 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
42 INT52179 Regulation of Lbp 39 0.61 25.4 18.32
43 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16
44 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
45 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67
46 INT104550 Positive_regulation of Il18 67 0.70 55.14 17.48
47 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
48 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
49 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
50 INT68913 Gene_expression of Cd14 55 0.76 38.99 15.67
51 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
52 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
53 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
54 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
55 INT11069 Positive_regulation of Pf4 35 0.68 27.7 13.96
56 INT4931 Localization of IFNG 53 0.78 33.25 13.65
57 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
58 INT142621 Positive_regulation of Gene_expression of CD36 38 0.70 15.18 13.4
59 INT141014 Positive_regulation of Gene_expression of Il18 46 0.68 47.63 13.3
60 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
61 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
62 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
63 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
64 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
65 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
66 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32
67 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
68 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
69 INT14962 Gene_expression of Pf4 27 0.76 22.48 10.88
70 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68
71 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65
72 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
73 INT135022 Gene_expression of Cd14 79 0.76 36.37 10.63
74 INT87393 Gene_expression of Ccr5 19 0.65 11 10.51
75 INT150540 Binding of TLR2 50 0.45 35.86 10.43
76 INT57000 Localization of LBP 21 0.78 11.01 10.01
77 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53
78 INT155808 Gene_expression of Ccl4 24 0.65 21.36 9.18
79 INT226463 Positive_regulation of IL23A 23 0.45 21.58 9.18
80 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05
81 INT32624 Regulation of LBP 15 0.60 11.48 8.71
82 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
83 INT73234 Positive_regulation of Lbp 13 0.69 12.55 8.57
84 INT77790 Positive_regulation of Gene_expression of Tnfrsf1a 16 0.67 15.88 8.5
85 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47
86 INT209866 Regulation of Gene_expression of CD36 27 0.60 10.04 8.42
87 INT99163 Positive_regulation of Cd14 18 0.49 16.02 7.91
88 INT117543 Regulation of Gene_expression of CD14 21 0.59 6.66 7.67
89 INT94127 Positive_regulation of Il18 14 0.69 14 7.47
90 INT38503 Positive_regulation of Ripk2 11 0.67 2.9 7.47
91 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
92 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
93 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
94 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
95 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
96 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02
97 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
98 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67
99 INT117544 Regulation of CD14 24 0.45 5.85 6.66
100 INT207892 Binding of Tlr9 35 0.46 26.66 6.61
101 INT91721 Binding of IL18 21 0.48 21.17 6.56
102 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4
103 INT275265 Negative_regulation of Positive_regulation of Tnfrsf1a 1 0.56 4.41 6.35
104 INT150023 Positive_regulation of Il23a 25 0.38 18.33 6.32
105 INT74154 Transcription of Ifng 14 0.67 10.33 6.21
106 INT183910 Negative_regulation of Gene_expression of Lbp 10 0.35 9.78 6.15
107 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12
108 INT104547 Negative_regulation of Il18 24 0.59 17.89 6.01
109 INT97797 Localization of TLR4 18 0.77 13.78 6
110 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
111 INT19941 Negative_regulation of Pf4 13 0.42 10.35 5.97
112 INT275272 Positive_regulation of Positive_regulation of Tnfrsf1a 8 0.48 6.44 5.97
113 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
114 INT15132 Gene_expression of TNFRSF1A 33 0.75 20.09 5.93
115 INT120089 Negative_regulation of Ccr5 7 0.58 10.36 5.91
116 INT5186 Regulation of Ifng 11 0.45 8.78 5.9
117 INT94118 Localization of Tnfrsf1a 9 0.72 7.24 5.81
118 INT103847 Positive_regulation of Ccr5 11 0.55 6.04 5.79
119 INT181406 Binding of Ccr5 16 0.45 17 5.78
120 INT135028 Positive_regulation of Cd14 34 0.59 16.19 5.73
121 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
122 INT105538 Negative_regulation of Tnfrsf1a 16 0.56 12.51 5.61
123 INT124705 Binding of Il18 29 0.47 19.02 5.59
124 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53
125 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
126 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43
127 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41
128 INT111520 Regulation of Tnfrsf1a 10 0.61 7.25 5.41
129 INT164656 Negative_regulation of Gene_expression of CD36 24 0.57 6.51 5.39
130 INT94028 Regulation of Twist1 37 0.44 22.41 5.33
131 INT197491 Gene_expression of Myd88 32 0.74 14.59 5.29
132 INT174688 Binding of Tlr2 45 0.42 36.65 5.25
133 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
134 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18
135 INT1029 Positive_regulation of Gene_expression of Lbp 17 0.50 11.03 5.18
136 INT170470 Binding of CD14 27 0.35 14.89 5.16
137 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
138 INT175312 Positive_regulation of Gene_expression of IL23A 17 0.45 14.8 5.05
139 INT37976 Binding of Ripk2 6 0.47 0.27 5.01
140 INT166878 Regulation of Ccl3 9 0.44 8.21 4.81
141 INT62132 Regulation of Gene_expression of Ifng 12 0.62 1.28 4.77
142 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
143 INT185398 Negative_regulation of Gene_expression of TLR2 34 0.55 27.21 4.73
144 INT153269 Binding of Ccl3 10 0.48 8.87 4.69
145 INT104549 Localization of Il18 16 0.78 13.01 4.64
146 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54
147 INT20459 Regulation of Ripk2 5 0.44 0 4.53
148 INT11106 Gene_expression of Lbp 10 0.67 10.29 4.52
149 INT92821 Positive_regulation of Gene_expression of Cd14 15 0.66 9.82 4.5
150 INT188672 Positive_regulation of Tlr9 15 0.67 13.1 4.48
151 INT93739 Positive_regulation of Gene_expression of Tnfrsf1a 11 0.66 11.17 4.44
152 INT204783 Positive_regulation of Gene_expression of Il23a 17 0.36 15.53 4.42
153 INT142752 Positive_regulation of Myd88 26 0.66 12.07 4.4
154 INT118230 Binding of Tnfrsf1a 15 0.42 7.63 4.39
155 INT165891 Transcription of Il18 5 0.69 7.63 4.37
156 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
157 INT187836 Binding of Tnfrsf1a 19 0.46 18.08 4.33
158 INT97131 Positive_regulation of CD14 25 0.67 12.03 4.21
159 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2
160 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15
161 INT149986 Positive_regulation of Gene_expression of Tlr9 5 0.67 8.18 4.15
162 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07
163 INT133602 Positive_regulation of Fadd 2 0.54 0.38 4.02
164 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99
165 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
166 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89
167 INT103843 Positive_regulation of Gene_expression of Ccr5 5 0.42 2.31 3.89
168 INT35175 Localization of IL18 18 0.80 12.96 3.83
169 INT144083 Positive_regulation of Gene_expression of Ccl3 10 0.50 8.16 3.81
170 INT142754 Binding of Myd88 20 0.36 9.61 3.8
171 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
172 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
173 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
174 INT141015 Regulation of Il18 14 0.59 6.3 3.73
175 INT158596 Binding of Tlr3 24 0.47 11.66 3.69
176 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65
177 INT133169 Positive_regulation of Il12b 25 0.49 13 3.64
178 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
179 INT133733 Positive_regulation of Localization of Lbp 6 0.43 9.19 3.61
180 INT77786 Negative_regulation of Tnfrsf1a 5 0.56 5.03 3.58
181 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
182 INT77788 Regulation of Tnfrsf1a 14 0.57 11.24 3.53
183 INT148151 Regulation of Il18 7 0.28 5.4 3.5
184 INT133604 Negative_regulation of Fadd 4 0.57 0.81 3.5
185 INT26702 Transcription of CD36 17 0.70 3.56 3.49
186 INT11101 Regulation of Gene_expression of Lbp 6 0.61 5.43 3.49
187 INT96700 Positive_regulation of Positive_regulation of Tnfrsf1a 6 0.69 3.93 3.42
188 INT11107 Binding of Lbp 12 0.42 4.42 3.41
189 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4
190 INT181357 Negative_regulation of Ccl3 12 0.59 13.09 3.38
191 INT264970 Positive_regulation of Localization of TLR2 1 0.11 4.21 3.37
192 INT97138 Positive_regulation of Gene_expression of CD14 17 0.48 9.07 3.35
193 INT87027 Positive_regulation of Localization of IFNG 12 0.67 5.78 3.35
194 INT52899 Positive_regulation of TNFRSF1A 16 0.46 19.04 3.34
195 INT56601 Positive_regulation of Ccl4 9 0.47 6.27 3.28
196 INT185738 Binding of Cd14 28 0.45 14.41 3.25
197 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
198 INT250884 Binding of IL23A 5 0.19 7.17 3.17
199 INT163269 Binding of Il23a 11 0.44 7.2 3.14
200 INT153346 Binding of Cd14 11 0.31 8.64 3.06
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