GO:0032794

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Name GTPase activating protein binding
Categary Function
Go Slim No
Go Link GO:0032794
Unique Molecular Interactions 76
Total Molecular Interactions 92
Total Single Events 997
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for GTPase activating protein binding. They are ordered first by their pain relevance and then by number of times they were reported for GTPase activating protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17
2 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
3 INT202810 Pin1 Regulation of Csf2 1 0.03 0.82 0.36
4 INT202808 Binding of Pin1 and Hnrpd 1 0.08 0.84 0.22
5 INT130932 Negative_regulation of Cpox Positive_regulation of Gene_expression of TSC1 1 0.00 0.42 0.18
6 INT316482 Il6 Positive_regulation of Cdh1 1 0.03 0.33 0.15
7 INT202813 Pin1 Positive_regulation of Regulation of TH1L 1 0.50 0 0.14
8 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13
9 INT74014 Binding of TSC1 and XRCC1 1 0.02 1.98 0.09
10 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09
11 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09
12 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08
13 INT137251 BCL2L11 Regulation of CDH1 1 0.17 0.99 0.08
14 INT202807 Pin1 Regulation of Binding of Hnrpd 1 0.06 0.14 0.08
15 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07
16 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
17 INT349916 Binding of Ctnnd1 and Cdh1 1 0.17 0.47 0.07
18 INT269210 CDH1 Positive_regulation of Positive_regulation of ITK 1 0.06 0.84 0.06
19 INT251373 Binding of Cdh2 and Cdh1 1 0.17 0 0.04
20 INT246793 Binding of Tsc2 and Tsc1 1 0.04 0.71 0.04
21 INT269214 SNAI1 Positive_regulation of Positive_regulation of CDH1 1 0.35 0.71 0.04
22 INT269211 SNAI1 Positive_regulation of Gene_expression of CDH1 1 0.40 0.73 0.04
23 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03
24 INT272009 Binding of YWHAQ and Tsc1 1 0.37 0.14 0.03
25 INT341537 F2RL1 Positive_regulation of TSC1 1 0.01 0.76 0.03
26 INT251370 Cdh2 Regulation of Gene_expression of Cdh1 1 0.21 0.35 0
27 INT298450 Binding of CDH1 and Efs 1 0.03 0.96 0
28 INT246808 Tsc2 Regulation of Regulation of Tsc1 1 0.02 0.05 0
29 INT355588 Binding of CDH1 and CTNNA1 1 0.00 1.12 0
30 INT175624 Gene_expression of CDH2 Positive_regulation of CDH1 1 0.00 1.12 0
31 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0
32 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0
33 INT331222 Tsc1 Negative_regulation of Mtor 1 0.00 0.68 0
34 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
35 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0
36 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0
37 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0
38 INT312318 Binding of Cdh1 and Regulation of Transcription of Prl 1 0.30 0.39 0
39 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0
40 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0
41 INT259093 Binding of TSC1 and LMO4 1 0.02 0.74 0
42 INT310042 Binding of Cdh1 and Lsr1 1 0.01 0.09 0
43 INT287891 Binding of CDH1 and KRT20 1 0.00 0.5 0
44 INT217786 TSC1 Regulation of MITF 1 0.00 1.27 0
45 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
46 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0
47 INT259092 TSC1 Positive_regulation of Gene_expression of TCEAL1 1 0.01 4.58 0
48 INT268596 Mir10a Regulation of TSC1 1 0.01 0.44 0
49 INT272008 Tsc1 Negative_regulation of Binding of HERC1 1 0.01 0.32 0
50 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0
51 INT300337 Gene_expression of MITF Negative_regulation of Gene_expression of TSC1 1 0.00 0.65 0
52 INT269213 Binding of SNAI1 and Positive_regulation of Gene_expression of CDH1 1 0.37 1.03 0
53 INT312316 Gene_expression of Cdh1 Negative_regulation of Prl 1 0.29 0 0
54 INT217784 Binding of MITF and TSC1 1 0.00 1.21 0
55 INT272014 Binding of RB1CC1 and Tsc1 1 0.05 0.44 0
56 INT331223 Negative_regulation of Tsc1 Positive_regulation of Positive_regulation of Mtor 1 0.01 0.33 0
57 INT337407 MIR200A Positive_regulation of CDH1 1 0.00 0.29 0
58 INT217774 TP53 Regulation of TSC1 1 0.02 1.28 0
59 INT251372 Cdh1 Regulation of Gene_expression of Cdh2 1 0.21 0.35 0
60 INT217791 TP53 Positive_regulation of TSC1 1 0.04 0.61 0
61 INT300631 Binding of TSC1 and TSC2 1 0.15 2.59 0
62 INT271998 Cdk1 Positive_regulation of Phosphorylation of Tsc1 1 0.17 0.3 0
63 INT310039 Binding of Cdh1 and Slc30a4 1 0.04 0.46 0
64 INT268509 MIR146B Regulation of TSC1 1 0.03 0.44 0
65 INT298438 Binding of CDH1 and SNAI1 1 0.14 1.16 0
66 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0
67 INT271986 Tsc1 Regulation of Skp2 1 0.13 0.14 0
68 INT232594 CDH1 Regulation of HEPACAM 1 0.01 1.02 0
69 INT312317 Cdh1 Regulation of Transcription of Prl 1 0.41 0.39 0
70 INT331221 Binding of Akt1 and Tsc1 1 0.03 0.33 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for GTPase activating protein binding. They are ordered first by their pain relevance and then by number of times they were reported in GTPase activating protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
2 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77
3 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
4 INT146350 Phosphorylation of Rgs14 1 0.80 0.79 3.77
5 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
6 INT202792 Negative_regulation of Pin1 1 0.56 3.77 2.37
7 INT169705 Negative_regulation of Gene_expression of Cdh1 10 0.57 8.8 2.1
8 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
9 INT111603 Positive_regulation of Gene_expression of CDH1 14 0.49 11.17 1.72
10 INT126276 Regulation of Rgs14 1 0.39 0.71 1.63
11 INT214073 Binding of TSC1 9 0.37 22 1.34
12 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28
13 INT146351 Positive_regulation of Phosphorylation of Rgs14 1 0.45 0.27 1.23
14 INT122103 Negative_regulation of Cdh1 5 0.49 2.05 1.18
15 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15
16 INT111605 Positive_regulation of CDH1 12 0.50 7.95 1.15
17 INT169704 Regulation of Gene_expression of Cdh1 4 0.35 1.75 1.09
18 INT126279 Gene_expression of Rgs14 1 0.67 0.34 0.98
19 INT73465 Transcription of TSC1 4 0.07 3.47 0.96
20 INT202790 Binding of Pin1 1 0.46 3.02 0.88
21 INT276620 Negative_regulation of Cdh1 7 0.57 6.48 0.86
22 INT202786 Regulation of Pin1 1 0.43 2.16 0.83
23 INT74019 Regulation of TSC1 27 0.35 23.61 0.79
24 INT235069 Localization of Cdh1 9 0.74 3.81 0.71
25 INT86370 Regulation of CDH1 10 0.54 13.89 0.7
26 INT189877 Gene_expression of Cdh1 55 0.58 9.36 0.66
27 INT202806 Gene_expression of Pin1 1 0.74 1.87 0.66
28 INT285478 Negative_regulation of Rgs14 1 0.27 1.25 0.6
29 INT105959 Positive_regulation of Gene_expression of Cdh1 5 0.49 2.65 0.57
30 INT202801 Positive_regulation of Pin1 1 0.67 1.37 0.52
31 INT301995 Regulation of Cdh1 5 0.44 3.8 0.48
32 INT271939 Regulation of Tsc1 2 0.41 1.16 0.47
33 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45
34 INT202805 Negative_regulation of Negative_regulation of Pin1 1 0.41 0.77 0.43
35 INT172558 Positive_regulation of Cdh1 11 0.49 8.92 0.42
36 INT163489 Binding of CDH1 13 0.19 8.63 0.35
37 INT127871 Regulation of Gene_expression of CDH1 4 0.44 2.34 0.34
38 INT184803 Localization of TSC1 5 0.37 6.13 0.32
39 INT256540 Regulation of Gene_expression of TSC1 4 0.07 4.74 0.3
40 INT202791 Phosphorylation of Pin1 1 0.78 0.61 0.28
41 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26
42 INT234858 Binding of Cdh1 11 0.47 4.58 0.22
43 INT215000 Transcription of Cdh1 4 0.40 1.17 0.22
44 INT202789 Positive_regulation of Gene_expression of Pin1 1 0.67 0.62 0.22
45 INT217832 Negative_regulation of Gene_expression of TSC1 5 0.04 5.45 0.21
46 INT254701 Transcription of CDH1 6 0.67 2.5 0.17
47 INT202796 Regulation of Negative_regulation of Pin1 1 0.59 0.23 0.15
48 INT202797 Negative_regulation of Binding of Pin1 1 0.41 0.74 0.15
49 INT164160 Localization of CDH1 8 0.66 3.39 0.14
50 INT202794 Negative_regulation of Protein_catabolism of Pin1 1 0.41 0.15 0.11
51 INT202793 Protein_catabolism of Pin1 1 0.63 0.15 0.11
52 INT296622 Positive_regulation of Gene_expression of Cdh1 3 0.52 2.24 0.09
53 INT296623 Positive_regulation of Cdh1 2 0.35 1.88 0.09
54 INT173222 Negative_regulation of Negative_regulation of TSC1 1 0.01 0.92 0.09
55 INT276619 Negative_regulation of Transcription of Cdh1 1 0.24 0.57 0.09
56 INT251364 Negative_regulation of Gene_expression of Cdh1 4 0.32 1.02 0.07
57 INT190703 Regulation of Negative_regulation of TSC1 3 0.06 3.08 0.07
58 INT271938 Binding of Tsc1 1 0.43 3.18 0.07
59 INT269223 Positive_regulation of Localization of CDH1 1 0.38 0.84 0.06
60 INT349912 Negative_regulation of Negative_regulation of Cdh1 1 0.42 1.04 0.05
61 INT189881 Binding of Cdh1 6 0.36 1.24 0.04
62 INT271914 Negative_regulation of Tsc1 5 0.38 3.08 0.04
63 INT251361 Transcription of Cdh1 1 0.36 0 0.04
64 INT349906 Negative_regulation of Localization of Cdh1 1 0.42 0.37 0.04
65 INT271930 Gene_expression of Tsc1 1 0.69 6.88 0.04
66 INT246758 Gene_expression of Tsc1 1 0.11 0.55 0.04
67 INT190057 Positive_regulation of Negative_regulation of TSC1 2 0.01 1.08 0.03
68 INT271960 Positive_regulation of Binding of TSC1 1 0.25 0.88 0.03
69 INT190054 Negative_regulation of Positive_regulation of TSC1 1 0.01 0.83 0.03
70 INT287933 Negative_regulation of Binding of CDH1 1 0.03 0.65 0.03
71 INT271936 Phosphorylation of Tsc1 4 0.73 1.76 0
72 INT287949 Positive_regulation of Positive_regulation of CDH1 3 0.06 1.4 0
73 INT175424 Regulation of Transcription of TSC1 2 0.05 1.39 0
74 INT251359 Regulation of Cdh1 2 0.34 0.47 0
75 INT189878 Localization of Cdh1 2 0.56 0.34 0
76 INT271963 Phosphorylation of TSC1 2 0.31 2.02 0
77 INT263281 Negative_regulation of Transcription of CDH1 2 0.41 1.84 0
78 INT251362 Regulation of Gene_expression of Cdh1 2 0.46 0.4 0
79 INT298446 Negative_regulation of Negative_regulation of CDH1 1 0.15 0.59 0
80 INT350778 Regulation of Binding of CDH1 1 0.02 0.29 0
81 INT271965 Negative_regulation of Binding of TSC1 1 0.33 0.44 0
82 INT246748 Regulation of Tsc1 1 0.04 0.05 0
83 INT189879 Positive_regulation of Binding of Cdh1 1 0.08 0.15 0
84 INT301987 Negative_regulation of Positive_regulation of Cdh1 1 0.07 1.28 0
85 INT312313 Protein_catabolism of Cdh1 1 0.75 0.21 0
86 INT287950 Negative_regulation of Positive_regulation of CDH1 1 0.03 0.56 0
87 INT259156 Protein_catabolism of CDH1 1 0.16 0.38 0
88 INT346315 Negative_regulation of Regulation of CDH1 1 0.04 0.47 0
89 INT246773 Phosphorylation of Tsc1 1 0.13 0.05 0
90 INT349911 Regulation of Negative_regulation of Cdh1 1 0.44 0.23 0
91 INT271913 Protein_catabolism of Tsc1 1 0.51 0.45 0
92 INT271906 Negative_regulation of Binding of Tsc1 1 0.38 0.06 0
93 INT324055 Regulation of Transcription of Cdh1 1 0.09 0.49 0
94 INT271927 Positive_regulation of Tsc1 1 0.44 0.4 0
95 INT189883 Negative_regulation of Localization of Cdh1 1 0.07 0.06 0
96 INT271931 Negative_regulation of Gene_expression of Tsc1 1 0.38 0.44 0
97 INT322758 Positive_regulation of Localization of TSC1 1 0.06 1.4 0
98 INT331195 Positive_regulation of Negative_regulation of Tsc1 1 0.18 0.15 0
99 INT296611 Positive_regulation of Negative_regulation of Cdh1 1 0.11 0.78 0
100 INT269224 Regulation of Transcription of CDH1 1 0.20 0.86 0
101 INT310014 Phosphorylation of Cdh1 1 0.16 0.24 0
102 INT301989 Positive_regulation of Binding of Cdh1 1 0.08 0.42 0
103 INT246757 Binding of Tsc1 1 0.06 0.19 0
104 INT349904 Regulation of Localization of Cdh1 1 0.44 0.05 0
105 INT337474 Positive_regulation of Binding of CDH1 1 0.07 0.54 0
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