GO:0032808

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Name lacrimal gland development
Categary Process
Go Slim No
Go Link GO:0032808
Unique Molecular Interactions 26
Total Molecular Interactions 35
Total Single Events 218
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lacrimal gland development. They are ordered first by their pain relevance and then by number of times they were reported for lacrimal gland development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
2 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
3 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
4 INT214615 FOXC1 Positive_regulation of Gene_expression of Ang 1 0.01 0.29 0.28
5 INT214594 Binding of FOXC1 and IBD9 1 0.00 1.81 0.28
6 INT214591 FOXC1 Regulation of ICAM1 1 0.05 0.29 0.19
7 INT214593 Binding of FOXC1 and OAP 1 0.01 0.25 0.13
8 INT223535 Binding of HAND1 and Pax6 1 0.33 0.92 0.13
9 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
10 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
11 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07
12 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
13 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
14 INT303558 Binding of Fgfr2 and Dysf 1 0.01 0.44 0.03
15 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03
16 INT183091 Binding of FGF2 and FGFR2 1 0.03 0.79 0
17 INT185271 Pax6 Regulation of Psmd1 1 0.02 0 0
18 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
19 INT326729 Foxc1 Positive_regulation of Gene_expression of Ehf 1 0.23 0.26 0
20 INT183089 Positive_regulation of Binding of FGF2 and FGFR2 1 0.04 0.4 0
21 INT283716 Neurod1 Positive_regulation of Pax6 1 0.23 0.46 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for lacrimal gland development. They are ordered first by their pain relevance and then by number of times they were reported in lacrimal gland development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT39711 Negative_regulation of FOXC1 4 0.41 4.29 1.2
2 INT81311 Gene_expression of FOXC1 9 0.44 3.46 1.18
3 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
4 INT156427 Localization of FOXC1 2 0.73 1.36 1.07
5 INT214609 Positive_regulation of Gene_expression of FOXC1 1 0.08 1.78 1
6 INT46334 Binding of FOXC1 2 0.36 2.66 0.99
7 INT43131 Regulation of FOXC1 3 0.36 1.09 0.98
8 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
9 INT169421 Positive_regulation of FOXC1 4 0.49 2.42 0.7
10 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
11 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
12 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
13 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
14 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
15 INT128754 Binding of Foxc1 1 0.01 0.43 0.32
16 INT214611 Positive_regulation of Localization of FOXC1 1 0.07 0.34 0.26
17 INT176080 Gene_expression of Fgfr2 4 0.68 2.34 0.24
18 INT223739 Binding of Fgfr2 3 0.30 0.94 0.22
19 INT185254 Gene_expression of Pax6 14 0.72 1.77 0.16
20 INT185203 Regulation of Regulation of FOXC1 1 0.16 0 0.15
21 INT99718 Positive_regulation of Gene_expression of FGFR2 9 0.49 4.47 0.12
22 INT143835 Gene_expression of Foxc1 2 0.39 1.17 0.09
23 INT143833 Positive_regulation of Foxc1 2 0.42 1.02 0.09
24 INT143836 Negative_regulation of Foxc1 1 0.35 0.92 0.09
25 INT303546 Binding of Fgfr2 1 0.46 0.74 0.06
26 INT260760 Positive_regulation of Fgf10 2 0.53 0.43 0.03
27 INT206481 Transcription of Pax6 2 0.41 0.19 0.03
28 INT185206 Transcription of FOXC1 1 0.31 0 0.03
29 INT303535 Positive_regulation of Gene_expression of Fgf10 1 0.53 0.34 0.03
30 INT303525 Localization of Fgfr2 1 0.72 0.28 0.03
31 INT336419 Negative_regulation of Gene_expression of Pax6 1 0.45 0.12 0.03
32 INT185204 Positive_regulation of Transcription of FOXC1 1 0.27 0 0.03
33 INT303547 Positive_regulation of Negative_regulation of Fgfr2 1 0.48 1.07 0.03
34 INT185208 Positive_regulation of Positive_regulation of FOXC1 1 0.29 0 0.03
35 INT207729 Regulation of FGFR2 4 0.22 2.35 0
36 INT238985 Positive_regulation of FGFR2 3 0.49 1.19 0
37 INT99716 Transcription of FGFR2 2 0.34 0.22 0
38 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0
39 INT99715 Regulation of Gene_expression of FGFR2 2 0.22 0.19 0
40 INT303555 Negative_regulation of Gene_expression of FGFR2 2 0.41 0.31 0
41 INT248544 Transcription of Foxc1 2 0.67 0.48 0
42 INT291889 Negative_regulation of Pax6 2 0.45 0.39 0
43 INT202623 Negative_regulation of Gene_expression of Fgfr2 1 0.32 0 0
44 INT319036 Gene_expression of Fgfr2 1 0.48 0.08 0
45 INT324196 Positive_regulation of Gene_expression of Pax6 1 0.36 0 0
46 INT291888 Regulation of Gene_expression of Pax6 1 0.33 0 0
47 INT336416 Binding of Pax6 1 0.28 0 0
48 INT99717 Positive_regulation of Transcription of FGFR2 1 0.10 0.08 0
49 INT336420 Positive_regulation of Binding of Pax6 1 0.38 0 0
50 INT183117 Positive_regulation of Binding of FGFR2 1 0.09 0.81 0
51 INT291885 Regulation of Pax6 1 0.15 0 0
52 INT303524 Positive_regulation of Fgfr2 1 0.66 0.22 0
53 INT200852 Positive_regulation of Pax6 1 0.11 0 0
54 INT208927 Localization of Pax6 1 0.11 0 0
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